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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Design, Synthesis, Application and Mechanism of Functional Polymers

edited by Jingyuan Liu

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1302 | Submission Open

Keywords: functional polymers; polymer synthesis; structure–property relationship; molecular mode of actions; interfacial interaction; molecular design; smart materials; functional coatings; biomedical applications; energy storage

(This special issue belongs to the Section Materials Science)

Advanced Composite Materials: Innovative Molecular Design, Cross-Scale Materials Characterization and Integrated Engineering Applications

edited by

Zhengzhi Mu

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1272 | Submission Open

Keywords: composite materials; molecular design; cross-scale characterization; advanced synthesis; integrated applications

(This special issue belongs to the Section Materials Science)

Recent Advances in Rheumatic Diseases and Rheumatoid Arthritis

edited by

Ilaria Mormile

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1170 | Submission Open

Keywords: rheumatoid arthritis; systemic lupus erythematous; systemic sclerosis; Sjögren’s syndrome; psoriatic arthritis; rare autoimmune rheumatic diseases; vasculitis; biological therapies

(This special issue belongs to the Section Molecular Immunology)

Polymer Biocomposites: Synthesis, Applications and End-Life

edited by

Maria Chiara Mistretta

and

Manuela Ceraulo

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1154 | Submission Open

Keywords: polymer biocomposites; biodegradable polymers; molecular design and synthesis; functional modifications; biodegradation

(This special issue belongs to the Section Materials Science)

The Role of Toll-Like Receptors (TLRs) in Infection and Inflammation: 4th Edition

edited by

Ralf Kircheis

and

Oliver Planz

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1098 | Submission Open

Keywords: toll-like receptors (TLR); pathogen associated molecular patterns (PAMPs); sepsis; bacterial infections; viral infections; Myd88; TRIF; NF-kappaB; COVID-19; coagulopathies

(This special issue belongs to the Section Molecular Immunology)

Lung Cancer: Molecular Basis and Treatment Strategies

edited by

Hamada A.A. Noreldeen

submission deadline 20 Oct 2026 | Viewed by 1080 | Submission Open

Keywords: adenocarcinoma; oncogenic drivers; precision oncology; signal transduction; tumor microenvironment; targeted therapy; resistance mechanisms; epigenetics; biomarker discovery; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Pathophysiology of Nerve Regeneration

edited by Fabian Szepanowski and Mark Stettner

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1029 | Submission Open

Keywords: nerve injury; nerve inflammation; autoimmune neuropathies; immune-mediated neuropathies; polyneuropathies; peripheral neuroinflammation; nerve regeneration; Schwann cell; Schwann cell differentiation; repair Schwann cell

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Drug Discovery: Emerging Radiotracers and Small Molecule Inhibitors for Cancer and Neurological Disorders

edited by

Ramya Tokala

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1028 | Submission Open

Keywords: radiotracers; cytotoxic agents; drug discovery; molecular imaging; cancer therapy; neurological disorders; radiochemistry; medicinal chemistry; theranostics; drug development; molecular diagnostics

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Cell Adhesion

edited by

Surajit Bhattacharjya

submission deadline 20 Oct 2026 | Viewed by 989 | Submission Open

Keywords: cell adhesion; cell–cell communication; structures; drug discovery; integrins; cadherins; selectins

(This special issue belongs to the Section Molecular Biophysics)

Neural Stem Cells as Tools for Therapies: Challenges and Future Perspectives

edited by

Daniele Bottai

submission deadline 20 Oct 2026 | 1 articles | Viewed by 975 | Submission Open

Keywords: spinal cord injury; spinal muscular atrophy; amyotrophic lateral sclerosis; neurological diseases; neural stem cell differentiation; cellular models; transplantation; trophic factor release

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Amyloid-β: An Antimicrobial Defense Peptide

edited by

Anna Lia Asti

submission deadline 20 Oct 2026 | 1 articles | Viewed by 833 | Submission Open

Keywords: amyloid (Aß); aggregation prone regions (ARPs); lipopolysaccharide (LPS); amphipathic molecules; LL-37 peptide; neurodegeneration; aggregation inhibition; Alzheimer's disease (AD)

(This special issue belongs to the Section Molecular Biology)

Advanced Research in Crops: From Physiology to Breeding

edited by

Guang Chen

and Edyta Zdunek-Zastocka

submission deadline 20 Oct 2026 | 1 articles | Viewed by 807 | Submission Open

Keywords: crops; stress; cultivation measures; molecular mechanisms; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

The Plant Phenotyping and Phenomics for Breeding

edited by

Jaeil Lyu

submission deadline 20 Oct 2026 | Viewed by 740 | Submission Open

Keywords: plant phenomics; high-throughput phenotyping (HTP); genotype–phenotype association; non-invasive imag-ing; functional genomics; environmental interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Therapeutic Strategies for Oral Mucosal Diseases: From Radiotherapy-Induced Damage to Other Pathologies

edited by

Fernanda Gonçalves Salum

submission deadline 20 Oct 2026 | 1 articles | Viewed by 736 | Submission Open

Keywords: oral mucosal diseases; drug-induced oral lesions; radiotherapy- and chemotherapy-induced oral disorders; targeted therapy- and immunotherapy-induced stomatitis; oxidative stress and inflammation; oral microbiome and immunity; nanomedicine and biomaterials; photobiomodulation and photodynamic therapy; oral potentially malignant disorders; oral oncology; immune modulation; tissue regeneration and repair; translational research; investigational therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Electrochemical Detection: A Molecular-Level Perspective

edited by Katarzyna Fendrych and

Joanna Smajdor-Baran

submission deadline 20 Oct 2026 | 1 articles | Viewed by 703 | Submission Open

Keywords: electrochemical detection; molecular sensing; biosensors; nanostructured electrodes; biomolecular interactions; electroanalytical chemistry; molecular electrochemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Mitochondrial Disorders: From Molecular Mechanisms to New Therapies

edited by

Yury Ladilov

and

Muhammad Aslam

submission deadline 20 Oct 2026 | Viewed by 673 | Submission Open

Keywords: mitochondrial disorders; mitochondrial dysfunction; molecular mechanisms; targeted therapeutic approaches; mitochondrial biology regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Nanoparticles-Based Drug Delivery in Cancer Therapy

edited by

André F. Moreira

submission deadline 20 Oct 2026 | Viewed by 591 | Submission Open

Keywords: nanoparticle-based drug delivery; stimuli responsive; cancer targeting; theragnostic nanoparticles; protein corona; combinatorial drug therapies; tumor penetration; cancer cells uptake

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Immunotherapy for Cancer: From Molecular Basis to Novel Biomarkers and Therapeutic Targets—2nd Edition

edited by

Laura Conti

and

Valentina Audrito

submission deadline 20 Oct 2026 | 1 articles | Viewed by 532 | Submission Open

Keywords: tumor microenvironment; immune suppression; metabolic and molecular mechanisms of resistance to therapy; tumor immune escape; immunotherapy; immune checkpoint inhibitors; cancer vaccination; tumor-infiltrating cells; biomarkers; tumor antigens; cancer metabolism

(This special issue belongs to the Section Molecular Oncology)

The Impact of Circulating Biomarkers and Metabolites on Cardiometabolic Disease and Cancer: New Insights and Therapeutic Opportunities

edited by Melania Gaggini and

Cristina Vassalle

submission deadline 20 Oct 2026 | Viewed by 482 | Submission Open

Keywords: lipidomic; metabolomic; lipotoxicity; oxidative stress; amino acids; metabolic disease; cardiovascular risk; tumorigenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Progression in Inorganic Synthesis

edited by

Suraj Kumar Pathak

submission deadline 20 Oct 2026 | Viewed by 467 | Submission Open

Keywords: inorganic synthesis; materials science; catalysis; energy materials; bioinorganic systems; organometallic compounds; supramolecular chemistry; molecular design

(This special issue belongs to the Section Materials Science)

Molecular Insights into Allergic Asthma

edited by

Luisa Ricciardi

submission deadline 20 Oct 2026 | Viewed by 398 | Submission Open

Keywords: allergic asthma; molecular mechanisms; allergen exposure; T2 inflammation; inhaler treatment; biological treatment

(This special issue belongs to the Section Molecular Immunology)

Activation of the Blood–Brain Barrier and Neurological Dysfunction: 2nd Edition

edited by

Monique F. Stins

submission deadline 20 Oct 2026 | Viewed by 391 | Submission Open

Keywords: blood–brain barrier; neuro-infectious diseases; microbes; traumatic brain injury; Alzheimer’s disease; Parkinson’s disease; schizophrenia; cerebral vasculature; vascular heterogeneity; white matter; gray matter; therapeutic delivery; opening the BBB; neuro vascular unit

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of SARS-CoV-2 Infection and Pathogenesis

edited by

Virginia Lotti

and

Erica Diani

submission deadline 20 Oct 2026 | Viewed by 390 | Submission Open

Keywords: SARS-CoV-2; molecular virology; host–pathogen interactions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cancer Nanomedicine: Imaging, Targeting and Therapeutic Applications

edited by

Marvin Xavierselvan

and

Steven Fiering

submission deadline 20 Oct 2026 | Viewed by 379 | Submission Open

Keywords: cancer nanomedicine; multimodal imaging; nanoparticle drug delivery; tumor targeting; theranostic nanoparticles; combination therapies

(This special issue belongs to the Section Molecular Nanoscience)

Epigenetic Elicitation of Dormant Microorganisms for Anti-Cancer Therapy

edited by

Komal Anjum

submission deadline 20 Oct 2026 | Viewed by 316 | Submission Open

Keywords: dormant microbes; epigenetic; bioactive molecules; anti-cancer therapy; biosynthetic pathways; bioactive secondary metabolites

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer

edited by Radka S. Stoyanova

submission deadline 20 Oct 2026 | Viewed by 315 | Submission Open

Keywords: prostate cancer; molecular biomarkers; imaging; non-invasive biomarkers; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Advanced Molecular Research in Bio-Based Polymeric Materials

edited by

Wanwitoo Wanmolee

submission deadline 20 Oct 2026 | Viewed by 293 | Submission Open

Keywords: bio-based polymers; lignin; cellulose; biopolymers; sustainable materials; green chemistry; biomass valorization; biocomposites; functional materials; sustainable packaging

(This special issue belongs to the Section Materials Science)

Sustainable Nanomaterials for Environmental Remediation

edited by

Odín Reyes−Vallejo

and

Francisco J. Cano

submission deadline 20 Oct 2026 | Viewed by 282 | Submission Open

Keywords: nanomaterials; environmental remediation; adsorption; photocatalysis; membrane separation; biomass-derived materials; sustainable and conventional synthesis; CO2 capture and conversion; water, air, and soil treatment; structure–property relationships

(This special issue belongs to the Section Molecular Nanoscience)

Omics-Based Regulatory Networks in Plant Abiotic Stress Tolerance

edited by

Xujun Zhu

submission deadline 20 Oct 2026 | Viewed by 213 | Submission Open

Keywords: omics; plant abiotic stress tolerance; drought/salt/heat stress; genomics; transcriptomics; proteomics; metabolomics; epigenomics; stress regulatory networks; crop resilience

(This special issue belongs to the Section Molecular Plant Sciences)

The Involvement of Stem Cells in Cancer

edited by

Kuo-Shyang Jeng

submission deadline 20 Oct 2026 | Viewed by 211 | Submission Open

Keywords: cancer; stem cells; signaling pathways; self-renewal; treatment

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Obesity and Obesity Related Disorders: 4th Edition

edited by

Grażyna Nowicka

submission deadline 20 Oct 2026 | Viewed by 207 | Submission Open

Keywords: adipocyte biology; adipocyte tissue; adipocyte tissue dysfunction; cellular patterns; molecular patterns; epigenetics; gene expression; DNA damage; inflammation; oxidative stress; metabolic disorders; cancer

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Neural Damage and Fibrosis: From Mechanisms to Therapy

edited by

Savaș Kaya

and Ayça Taş

submission deadline 20 Oct 2026 | Viewed by 196 | Submission Open

Keywords: fibrosis; inflammation; oxidative stress; glial activation; neurodegeneration; gene expression; molecular signaling pathways; biomarkers; translational research

(This special issue belongs to the Section Molecular Neurobiology)

New Molecular Insights for Enhancing Plant Resilience to Abiotic Stress

edited by

Aliki Kapazoglou

submission deadline 20 Oct 2026 | Viewed by 174 | Submission Open

Keywords: abiotic stress; tolerance; plant resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiome

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Fatty Acids in Metabolic Disease

edited by

Danijela Ristić-Medić

and

Snježana Petrović

submission deadline 20 Oct 2026 | Viewed by 171 | Submission Open

Keywords: fatty acids; FADS; inflammation; insulin resistance; lipid mediators; lipid metabo-lism; lipotoxicity; metabolic diseases; nutrition; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Plant Genomics and Genetics: 4th Edition

edited by

Hengling Wei

submission deadline 20 Oct 2026 | Viewed by 169 | Submission Open

Keywords: plant genomics; plant genetics; abiotic stresses; salt resistance; genome; next-generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Microbiology in the Omics Era: Genomics, Metagenomics and Computational Insights

edited by

Fei Liu

submission deadline 23 Oct 2026 | 3 articles | Viewed by 13286 | Submission Open

Keywords: microbial genomics; metagenomics; computational biology; antimicrobial resistance; host–microbe interactions; multi-omics integration; bioinformatics tools; machine learning in microbiology

(This special issue belongs to the Section Molecular Microbiology)

Latest Advances in Oxidative Stress and Brain Injury

edited by

Vittorio Fineschi

submission deadline 23 Oct 2026 | 2 articles | Viewed by 12918 | Submission Open

Keywords: measurement of ROS; pathology of brain injuries; traumatic brain injuries; hypoxic–ischemic brain damage; experimental models of brain injury; targeted therapy of brain injuries; drug abuse and ROS; histological diagnosis of brain injuries; epigenetics of brain injuries; miRNA and prognosis of neural damage; novel approaches and proofs of principle in therapy; quality of life after brain injury

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Neuromuscular Mechanisms in Skeletal Muscle Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 23 Oct 2026 | 5 articles | Viewed by 12706 | Submission Open

Keywords: aging; sarcopenia; neuromuscular junction; molecular muscle modifications; myokines

(This special issue belongs to the Section Molecular Biology)

Antioxidants: The Molecular Guardians Against Oxidative Stress

edited by

Karolina A. Wojtunik-Kulesza

submission deadline 23 Oct 2026 | 5 articles | Viewed by 11063 | Submission Open

Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites

(This special issue belongs to the Section Biochemistry)

Eye Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Tomasz Chorągiewicz

and

Joanna Dolar-Szczasny

submission deadline 23 Oct 2026 | 5 articles | Viewed by 10859 | Submission Open

Keywords: eye diseases; genetic; biochemical; proteomic; cellular and physiological level; innovative therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Natural Products in Inflammation

edited by

Antonia Cianciulli

submission deadline 23 Oct 2026 | 3 articles | Viewed by 8395 | Submission Open

Keywords: inflammation; natural products; immunomodulation; bioactive compounds; drug discovery; drug target identification; anti-inflammatory activity; antioxidant activity; cellular signalling pathways

(This special issue belongs to the Section Molecular Pharmacology)

Recent Research on Biomimetic Chromatography, QSAR and Chemoinformatics in Molecular Modeling and Drug Design

edited by

Małgorzata Janicka

submission deadline 23 Oct 2026 | 5 articles | Viewed by 8316 | Submission Open

Keywords: biomimetic chromatography; QSARs; QRARs; molecular modelling; chemoinformatics; pharmacokinetics

(This special issue belongs to the Section Molecular Informatics)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 23 Oct 2026 | 2 articles | Viewed by 7961 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone–immune interface

(This special issue belongs to the Section Molecular Immunology)

Radiobiology—New Advances

edited by

Marco Calvaruso

and

Luigi Minafra

submission deadline 23 Oct 2026 | 3 articles | Viewed by 6245 | Submission Open

Keywords: radiobiology; radiotherapy; radiosensitizing agents; radioresistance; DNA damage; FLASH radiotherapy; particle therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 23 Oct 2026 | 4 articles | Viewed by 5804 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Antifungal Potential of Botanical Compounds

edited by Francisca Sempere-Ferre

submission deadline 23 Oct 2026 | 2 articles | Viewed by 5748 | Submission Open

Keywords: botanical compounds; antifungal agents; natural products; secondary metabolites; fungal growth inhibition; bioactive plant extracts; eco-friendly antifungals; natural product chemistry; sustainable antifungal solutions; plant-derived bioactives

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Inflammatory Bowel Disease: Molecular Insights—2nd Edition

edited by

Belal Chami

submission deadline 23 Oct 2026 | 4 articles | Viewed by 4724 | Submission Open

Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’s disease; ulcerative colitis; multiomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Alloy Materials Microstructure and Their Functionalization

edited by

Ozkan Gokcekaya

and Celaletdin Ergun

submission deadline 23 Oct 2026 | 2 articles | Viewed by 3776 | Submission Open

Keywords: alloy design; microstructure; production methods; additive manufacturing; sol–gel process; biofunctional materials; magnetic properties; nanoparticles; ceramics; composites

(This special issue belongs to the Section Materials Science)

Molecular Advancements in Functional Materials

edited by

Joanna Karasiewicz

submission deadline 23 Oct 2026 | 5 articles | Viewed by 3466 | Submission Open

Keywords: synthesis of specialty compounds; specialty compounds in functional materials; special applications: self-cleaning, anti-icing, self-healing, biocidal, etc., properties; special-purpose functional materials

(This special issue belongs to the Section Materials Science)

Molecular Research Advances in Common and Rare Pediatric Diseases

edited by

Lǎcrǎmioara Ionela Butnariu

submission deadline 23 Oct 2026 | 3 articles | Viewed by 3268 | Submission Open

Keywords: pediatric diseases; diagnosis; therapeutic targets; molecular mechanisms; pediatric pathology; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1051-1100 on page 22 of 62.

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