Neural Damage and Fibrosis: From Mechanisms to Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 October 2026 | Viewed by 139
Special Issue Editors
Interests: chemical reactivity; conceptual density functional theory; electronic structure principles; solid state chemistry; corrosion science; coordination compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neural damage and fibrosis are closely interconnected pathological processes that play a central role in the progression of many neurological and systemic diseases. Increasing evidence indicates that inflammatory signaling, oxidative stress, and dysregulated cellular communication contribute significantly to neuronal injury and subsequent fibrotic remodeling. In particular, glial activation, molecular signaling pathways, and gene expression alterations are key drivers of both neurodegeneration and tissue fibrosis. Understanding these complex mechanisms is essential in identifying novel biomarkers and developing effective therapeutic strategies. We are pleased to invite you to contribute to this Special Issue, which will provide new insights into the molecular basis behind neural damage and fibrosis.
This Special Issue will explore molecular, biochemical, and translational aspects of neural injury and fibrotic processes, with a focus on their roles in disease progression and therapeutic response. This topic aligns well with the scope of the International Journal of Molecular Sciences, particularly within the fields of molecular biology, biochemistry, and pathophysiology. By integrating experimental, clinical, and multi-omics approaches, this Special Issue will advance our understanding of signaling pathways, biomarker discovery, and targeted treatment strategies. Our goal is to compile a high-quality collection of at least 10 articles that contribute to both scientific knowledge and clinical applications.
For this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following:
- Molecular mechanisms of neural damage and fibrosis;
- Inflammation, oxidative stress, and glial activation;
- Receptor-mediated signaling pathways and cellular communication;
- Gene expression and epigenetic regulation;
- Neurodegeneration and tissue remodeling;
- Biomarker discovery and validation;
- Multi-omics approaches (genomics, proteomics, metabolomics);
- Experimental and clinical models of neural injury;
- Translational research and therapeutic targets;
- Novel treatment strategies for neural damage or fibrosis.
We look forward to receiving your contributions.
Dr. Savaș Kaya
Guest Editor
Dr. Ayça Taş
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- fibrosis
- inflammation
- oxidative stress
- glial activation
- neurodegeneration
- gene expression
- molecular signaling pathways
- biomarkers
- translational research
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
