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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plant Pathogen Interactions: 3rd Edition

edited by

Sixue Chen

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3845 | Submission Open

Keywords: pathogenicity; plant immunity; pattern-triggered immunity (PTI); effector-triggered immunity (ETI); effectors; avirulent; virulent; biotroph; necrotrophy; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Regenerative Medicine: Molecular Mechanisms Driving Tissue Regeneration and Repair

edited by

Christopher Robinson

and Paul Jordan Christo

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3695 | Submission Open

Keywords: stem cell; cell signaling; immune modulation; extracellular matrix; remodeling; gene regulation; gene editing; growth factors; extracellular vesicles; small molecules

(This special issue belongs to the Section Molecular Biology)

New Insights into Adipose Tissue Metabolic Function and Dysfunction, 4th Edition

edited by

Federica Mannino

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3621 | Submission Open

Keywords: inflammation; browning; thermogenesis; adipogenesis; diabetes; adipokines; energy storage; insulin resistance; obesity; lipolysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Focus on Metabolic Research Priorities in PCOS

edited by

Jim Parker

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3486 | Submission Open

Keywords: polycystic ovary syndrome; metabolism; insulin resistance; inflammation; hyperandrogenism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Crop Biotic and Abiotic Stress Tolerance: 4th Edition

edited by

Fazhan Qiu

submission deadline 20 Jun 2026 | 4 articles | Viewed by 3468 | Submission Open

Keywords: biotic and abiotic stress tolerance; QTL/gene mapping and clones; gene editing; marker-assisted selection; genomic breeding

(This special issue belongs to the Section Molecular Plant Sciences)

MicroRNA (miRNA) Technology in Cancer

edited by

Duncan Ayers

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3399 | Submission Open

Keywords: miRNA; microRNA; cancer; oncology; drug delivery; technology; non-coding RNA

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances on Solubility and Diffusivity in Water-Based Systems and in Biological Media

edited by

Ana M. Mainar

and

José S. Urieta

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3208 | Submission Open

Keywords: water solubility ; water-solute interactions ; solvation; hydrophobic and hydrophilic effects ; improving water solubility and prediction ; solution of chemicals in biological media ; diffusivity ; drug transport and bioavailability; chemicals diffusivity across biological barriers

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Plant Tolerance to Stress

edited by

Xingguo Li

submission deadline 20 Jun 2026 | 5 articles | Viewed by 3170 | Submission Open

Keywords: plant; genetic breeding; biotic stress; abiotic stress; gene regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Bioactive Compounds and Their Antioxidant Role: 2nd Edition

edited by Tamara Jurina

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2981 | Submission Open

Keywords: bioactive compounds; antioxidants; polyphenolic compounds; nutraceuticals; phytochemicals; bioavailability; medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Aspects of Reproductive Medicine

edited by Wei Chen

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2729 | Submission Open

Keywords: spermatogenesis; oogenesis; microenvironment; organ interactions; molecular regulation; gametogenesis; signaling pathways; reproductive disorders

(This special issue belongs to the Section Molecular Biology)

Cancer Biology: From Genetic Aspects to Treatment, 2nd Edition

edited by

Silvia Cantara

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2194 | Submission Open

Keywords: cancer biology; cancer biomarker; cancer progression; cancer metastasis; genetic of cancer

(This special issue belongs to the Section Molecular Oncology)

Extracellular Vesicles: Advances in Multi-Omics

edited by

Leo Kei Iwai

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2160 | Submission Open

Keywords: extracellular vesicles; omics; mass spectrometry; molecular targets; biomarker

(This special issue belongs to the Section Molecular Biology)

Role of Immune Cells in Cancers

edited by Helga Maria Schmetzer

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2043 | Submission Open

Keywords: cancer; immune monitoring; immune escape; immune activation

(This special issue belongs to the Section Molecular Oncology)

Advances in Brassica Crop Metabolism and Genetics (Second Edition)

edited by

Bo Sun

and

Honghao Lv

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1814 | Submission Open

Keywords: brassica crop; genomics; transcriptomics; proteomics; metabolomics; gene editing; metabolite synthesis and regulation; phylogeny and taxonomy; physiological traits; biotic/abiotic stresses; biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research in Epilepsy

edited by

Kinga Borowicz

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1810 | Submission Open

Keywords: epilepsy; epileptogenesis; antiepileptic drugs; drug resistance; interactions of antiepileptic drugs; multi-omics in epilepsy

(This special issue belongs to the Section Molecular Neurobiology)

Obesity and Cancer Risk: Molecular Mechanisms and Perspectives

edited by

Hendrik Lehnert

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1610 | Submission Open

Keywords: epidemiology of obesity and cancer; experimental models of cancer in obesity; genetic and epigenetics of obesity and metabolic dysfunction associated cancer; tumor microenvironment; basis of metastatic spread of cancer in obesity; therapeutic modeling and targeting

(This special issue belongs to the Section Molecular Oncology)

Non-Coding RNAs’ Functionality—Diagnosis and Therapy in Cancer and Other Indications (2nd Edition)

edited by

Mohamed Raafat El-Gewely

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1555 | Submission Open

Keywords: non-coding RNAs (ncRNAs); long non-coding RNAs (lncRNAs); MicroRNAs (miRNAs); circular RNAs (circRNAs); epigenetic and post-transcriptional regulation; epithelial– mesenchymal transition (EMT); cell proliferation and Apoptosis; biomarkers and Liquid biopsy; RNA-based therapeutics; next-generation sequencing (NGS); CRISPR/Cas9 screening; single-cell RNA sequencing (scRNA-seq); RNA interference (RNAi); cancer stem cells; early cancer diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecular Mechanisms of Genotoxicity

edited by Francesca Marcon and

Roberta Meschini

submission deadline 20 Jun 2026 | Viewed by 1528 | Submission Open

Keywords: DNA damage; DNA repair; genotoxicity; carcinogenesis; chronic degenerative diseases; human health; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

miRNAs in Cancers: From Molecular Biology to Treatment

edited by

Laura Mosca

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1527 | Submission Open

Keywords: cancer; miRNA; epigenetic

(This special issue belongs to the Section Molecular Biology)

Cardiac Repair and Regeneration: From Pathogenesis to Therapeutic Perspectives

edited by Marina Leone and Olaf Bergmann

submission deadline 20 Jun 2026 | Viewed by 1492 | Submission Open

Keywords: heart regeneration; cardiomyocyte proliferation; cell cycle; ischemic heart disease; myocardial infarction; stem cells; cardiac repair; polyploidization; tissue engineering; immune cells; metabolism; cell death

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Compounds from Foods Against Diseases

edited by Jongbin Lim

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1459 | Submission Open

Keywords: diet-related diseases; bioactive compounds; analytical techniques; functional foods; molecular interaction; health benefits

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nutrition, Inflammation, and Chronic Kidney Disease

edited by

Denise Mafra

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1426 | Submission Open

Keywords: chronic kidney disease; inflammation; nutrients; bioactive compounds

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Upper and Lower Airway Diseases in Allergy and Immunology: From Bench to Bedside

edited by

Giovanni Paoletti

Giulia Costanzo

and

Enrico Marco Heffler

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1376 | Submission Open

Keywords: unified airway disease; allergic rhinitis; asthma; chronic rhinosinusitis; eosinophilic; airway inflammation; airway epithelial barrier; immune dysregulation; respiratory microbiome; biomarkers; allergy and immunology

(This special issue belongs to the Section Molecular Immunology)

Advances in Traits in Animals and Aquatic Species, and Their Improvement Technologies

edited by

Lishi Yang

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1374 | Submission Open

Keywords: biotechnology; genetic breeding; stress responses; epigenetics; non-coding RNAs; gene regulation; molecular ecology; animals; aquaculture; development

(This special issue belongs to the Section Molecular Biology)

Conversion and Valorization of Lignocellulosic Biomass

edited by

Loredana Marcolongo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1271 | Submission Open

Keywords: lignocellulosic biomass; vegetal and agro processing wast; catalytic and biocatalytic conversion; value added products; lignocellulosic platform; bioprocessing; biorefinery; green chemistry; circular economy; bioeconomy

(This special issue belongs to the Section Biochemistry)

Molecular Research on Orchid Plants: 2nd Edition

edited by Wen‑Chieh Tsai

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1262 | Submission Open

Keywords: orchid; genomics; genome; genes; tumor; inflammation; drug; transcriptomics

(This special issue belongs to the Section Molecular Plant Sciences)

Research on System Biology Methods and Tools for Integrating Omics Data

edited by Yuanyan Xiong

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1081 | Submission Open

Keywords: systems biology; multi-omics integration; network analysis; computational biology; bioinformatics tools; machine learning; precision medicine

(This special issue belongs to the Section Molecular Informatics)

Antibacterial Nanomaterials for Medicinal Applications

edited by

Tsung-Rong Kuo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1020 | Submission Open

Keywords: nanotechnology; antibacterial; nanomaterials; toxicity; biocompatibility; medicinal applications

(This special issue belongs to the Section Molecular Nanoscience)

Plant Breeding Strategies: Employment of Plant Adaptation Mechanisms to Biotic and Abiotic Stresses

edited by

Vidmantas Bendokas

submission deadline 20 Jun 2026 | 2 articles | Viewed by 983 | Submission Open

Keywords: marker-assisted selection; molecular breeding; whole-transcriptome analysis; RNA sequencing; DNA sequencing; plant stress response

(This special issue belongs to the Section Molecular Plant Sciences)

Precision Cancer Medicine: Molecular Insights, Biological Events and Clinical Perspectives

edited by

Dimitrios H. Roukos

submission deadline 20 Jun 2026 | Viewed by 760 | Submission Open

Keywords: multi-omics at bulk level; single-cell multi-omics; precision oncology; precision immune-oncology; tumor molecular profiling

(This special issue belongs to the Section Molecular Oncology)

Multifaceted Roles of Extracellular Vesicles in Cancer and Other Diseases

edited by

Eleni Myrto Trifylli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 699 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer diagnostics; non-invasive tests; liquid biopsy; cancer therapy; biomarker discovery; nanotechnology; EV engineering; drug delivery; neurodegenerative diseases; cardiovascular diseases; infectious diseases; autoimmune diseases; precision diagnostics

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology of 3D Cell and Tissue Culture Systems: Benefits to Research and Disease Diagnostics

edited by

Thomas J. Goodwin

submission deadline 20 Jun 2026 | 1 articles | Viewed by 633 | Submission Open

Keywords: 3D physiological relevance vs. 2D biology; 3D research; and diagnostic systems; evolving 3D “ omics” applications; research and clinical medicine; drug applications; toxicity evaluations; “ Omics” ; spatial biology of 3D

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Leukemia: Molecular Immune Mechanisms

edited by

Mohammad Hojjat-Farsangi

submission deadline 20 Jun 2026 | Viewed by 562 | Submission Open

Keywords: leukemia; immune system; Genetic Mutations and Alterations; Immune Evasion Mechanisms; Immune Cell Dysfunction; Cytokine Networks; Bone Marrow Microenvironment; immunotherapy strategies

(This special issue belongs to the Section Molecular Immunology)

Molecular Research on Actinomycetes-Derived Natural Products

edited by Fong Tian Wong

submission deadline 20 Jun 2026 | Viewed by 536 | Submission Open

Keywords: actinomycetes; natural products; actinobacterial; genome mining; omics; secondary metabolites; genetic engineering; discovery; structural diversity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Cellular Aspects of Autoimmune and Inflammatory Rheumatic Diseases: Second Edition

edited by Marzena Helena Olesińska and Magdalena Szmyrka

submission deadline 20 Jun 2026 | Viewed by 392 | Submission Open

Keywords: autoimmune rheumatic diseases; inflammatory rheumatic diseases; arthritis; connective tissue diseases

(This special issue belongs to the Section Molecular Immunology)

Allosteric Modulation of Kinases in Cancer Therapeutic Strategies and Challenges

edited by

Nidhi Joshi

submission deadline 20 Jun 2026 | Viewed by 346 | Submission Open

Keywords: kinase signaling; allosteric modulators; cancer therapy; drug resistance; molecular mechanisms; protein– protein interactions; targeted therapy; conformational changes; ATP-competitive inhibitors; drug design

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into the Pathophysiology of Placenta Accreta Spectrum

edited by Jessian L. Munoz

submission deadline 20 Jun 2026 | Viewed by 325 | Submission Open

Keywords: placenta accreta; invasive placenta; trophoblasts; placenta; high-risk pregnancy; placenta previa; in vitro fertilization; biomarkers; multi-omics research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Compounds in Cancers: Second Edition

edited by

Patrícia M. A. Silva

Hassan Bousbaa

and

Honorina Cidade

submission deadline 20 Jun 2026 | Viewed by 312 | Submission Open

Keywords: anticancer strategies; bioactive compounds; natural products; synthetic products; medicinal chemistry; drug repurposing; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Telomeres in Development, Senescence and Genome Instability: 2nd Edition

edited by Michal Zalzman

submission deadline 20 Jun 2026 | Viewed by 303 | Submission Open

Keywords: telomere disorders and cell death; telomere factors as therapeutic targets in cancer; telomeres and genome stability; telomeres in aging and senescence

(This special issue belongs to the Section Molecular Genetics and Genomics)

Urothelial Cancer: From Translational Medicine to Recent Innovations in Therapeutic Management

edited by Alessio Bruni

submission deadline 20 Jun 2026 | Viewed by 299 | Submission Open

Keywords: urothelial cancer; bladder cancer; radiation therapy; trimodality approach; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Structural and Functional Insights into Chemokines and Chemokine Receptors in Immune Pathologies

edited by

Nidhi Joshi

submission deadline 20 Jun 2026 | Viewed by 270 | Submission Open

Keywords: chemokines; chemokine receptors; immune pathologies; signaling mechanisms; therapeutic targeting

(This special issue belongs to the Section Molecular Immunology)

The Chitosan Biomaterials: Advances and Challenges, 3rd Edition

edited by

Lacramioara Popa

Mihaela Violeta Ghica

and Cristina Elena Dinu-Pirvu

submission deadline 20 Jun 2026 | Viewed by 227 | Submission Open

Keywords: chitosan; chitosan biomaterials; chitosan derivatives; drug delivery; wound healing; tissue regeneration; dentistry; smart biomaterials

(This special issue belongs to the Section Materials Science)

Molecular Characterization of Glioblastoma: Implications for Diagnosis and Personalized Treatment

edited by Madan Mohan Kwatra

submission deadline 20 Jun 2026 | Viewed by 224 | Submission Open

Keywords: glioblastoma; diagnosis; molecular characterization; personalized treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis, Modification, and Functional Characterization of Advanced Biomaterials for Bone Tissue Engineering

edited by

Elisa Boanini

submission deadline 20 Jun 2026 | Viewed by 219 | Submission Open

Keywords: material functionalization; bioactive materials; antimicrobial; antibiofilm; coatings; scaffolds; bone cements; metal nanoparticles; controlled release; biocompatibility

(This special issue belongs to the Section Materials Science)

Sustainable Material Development Through Waste Utilization: From Molecular Insights to Functional Applications

edited by

Rosie Yagmur Yegin

submission deadline 20 Jun 2026 | Viewed by 202 | Submission Open

Keywords: sustainable materials; waste-derived materials; biodegradable polymers; green chemistry; functionalization; structure– property relationships; chemical modification; recycling; valorization; circular economy; composites; analytical techniques; industrial waste; agricultural waste

(This special issue belongs to the Section Materials Science)

Genomics and Epigenetics of Stem Cell: An Update

edited by

Vikas Malik

submission deadline 20 Jun 2026 | Viewed by 201 | Submission Open

Keywords: stem cells; epigenetics; genomics; cell fate; self-renewal; differentiation; regenerative medicine; transcription factors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Interplay Between Aging, Dementia and Renal Function: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Luca Soraci

submission deadline 20 Jun 2026 | Viewed by 200 | Submission Open

Keywords: aging; dementia; neuroinflammation; kidney– brain axis; translational research; biomarkers; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on the Major Histocompatibility Complex (MHC): From Bench to Bedside

edited by Antonio Arnaiz-Villena

submission deadline 20 Jun 2026 | Viewed by 197 | Submission Open

Keywords: HLA; immunology; HLA genetics and pharmacogenetics; immune and other functions of the MHC; classical and nonclassical MHC class I HLA genes; HLA-G; HLA-E; HLA-F; MHC evolution; complement; autoimmunity; immunodeficiency; cancer; HIV

(This special issue belongs to the Section Molecular Immunology)

Graphene-based Nanocomposites

edited by

Oleksandr Ivasenko

submission deadline 20 Jun 2026 | Viewed by 195 | Submission Open

Keywords: graphite intercalates; graphene; reduced graphene oxide; grafting; vertical heterostructures; nanocomposites; covalent organic frameworks (COFs); 2D nanomaterials; biomimetic interfaces; interfacial engineering

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Horizons in Pain Therapeutics

edited by Alaa Abd-Elsayed

submission deadline 20 Jun 2026 | Viewed by 194 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 3151-3200 on page 64 of 66.

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