Protein Regulation and Targeted Therapeutics in Neurodegenerative Disorders
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 August 2026 | Viewed by 145
Special Issue Editor
Interests: phytochemicals; neurodegenerative diseases; antioxidants; enzyme assay; cell-based assay; ROS
Special Issue Information
Dear Colleagues,
Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are closely linked to disturbances in protein regulation, including protein misfolding, aggregation, altered post-translational modifications, and impaired clearance mechanisms. This Special Issue will focus on recent progress in understanding how these protein-level changes contribute to disease onset and progression and how they can be targeted therapeutically. We invite original research and review articles that explore molecular and cellular pathways involved in protein dysfunction, as well as therapeutic approaches using small-molecule chemicals, natural compounds, biologics, gene-based strategies, and targeted protein modulation or degradation. Contributions that connect mechanistic insights with translational relevance, such as pharmacological intervention, biomarker development, or disease-modifying strategies, are especially welcome. Overall, this Special Issue will provide a balanced and practical perspective on protein regulation and therapeutic development in neurodegenerative disorders.
Dr. Niti Sharma
Guest Editor
Manuscript Submission Information
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Keywords
- neurodegeneration
- protein regulation
- protein aggregation
- small molecules
- therapeutic approaches
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