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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Role of Polyphenols and Polysaccharides in Human Diseases

edited by

Francisco Les

submission deadline 20 Sep 2026 | Viewed by 569 | Submission Open

Keywords: polyphenols; polysaccharides; bioactive compounds; chronic diseases prevention; functional foods

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Advances in Type 2 Diabetes and Its Complications: 2nd Edition

edited by

Anca Pantea Stoian

submission deadline 20 Sep 2026 | Viewed by 553 | Submission Open

Keywords: diabetes type 2; diabetes complications; pathophysiology of type 2 diabetes; new diabetes treatment; cardiovascular disease; stroke; peripheral artery disease; chronic kidney disease; retinopathy; neuropathy; non-alcoholic fatty liver disease in diabetes

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advancements in Prognostic and Predictive Biomarkers for Advanced Prostate Cancer

edited by

Daniel Khalaf

submission deadline 20 Sep 2026 | 1 articles | Viewed by 534 | Submission Open

Keywords: biomarkers; predictive biomarkers; prognostic biomarkers; genomic biomarkers; biomarker directed therapy; advanced prostate cancer; metastatic prostate cancer; circulating tumour DNA; precision oncology; systemic therapy

(This special issue belongs to the Section Molecular Oncology)

Environmental Exposures and Emerging Mechanisms in Chronic Obstructive Pulmonary Disease: From Pathogenesis to Precision Therapeutics

edited by

Abderrazzak Bentaher

submission deadline 20 Sep 2026 | Viewed by 532 | Submission Open

Keywords: chronic obstructive pulmonary disease; environmental exposures; disease pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Angiogenin: From Molecular Mechanisms to Clinical Implications

edited by

Iogann Tolbatov

submission deadline 20 Sep 2026 | Viewed by 514 | Submission Open

Keywords: angiogenin; angiogenesis; neuroprotection; cancer; neurodegeneration; biomarker; therapeutic target

(This special issue belongs to the Section Biochemistry)

Molecular Pathways and Mechanisms of Lung Injury: From Environmental Agents to Clinical Implications

edited by

Maria Lisa Garavaglia

and Cristina Porta

submission deadline 20 Sep 2026 | Viewed by 502 | Submission Open

Keywords: lung injury; lung cancer; pulmonary fibrosis; chronic obstructive pulmonary disease; acute respiratory distress syndrome; environmental pollutants and toxins; molecular and cellular mechanisms; biomarkers; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Age-Dependence of Neuroimmune Reactions

edited by

Babak Baban

submission deadline 20 Sep 2026 | Viewed by 501 | Submission Open

Keywords: age; neuroimmune dynamics; neuroimmune interaction; immune system; the central nervous system; age-related neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Molecular Immunology)

Autophagy and Viral Infections: The Era of New Therapeutical Strategies

edited by

Marisa Granato

submission deadline 20 Sep 2026 | Viewed by 493 | Submission Open

Keywords: autophagy; macroautophagy system; virus; viral infection; influenzae virus

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Gut and Oral Microbiota in Neurodevelopment: Molecular Biological Insights

edited by Ioannis Alexandros Charitos

submission deadline 20 Sep 2026 | Viewed by 490 | Submission Open

Keywords: neuroscience; central nervous system; peripheral nervous system; human microbiota; metabolome; gut–oral-microbiota–brain axis; neurodevelopment disorders; cognitive modulation; neurodegenerative diseases; psychobiotics

(This special issue belongs to the Section Molecular Microbiology)

Bioactive Compounds in Bee Products: Chemistry, Mechanisms of Action and Nutritional Applications

edited by

Jarosław Widelski

and

Ioanna Chinou

submission deadline 20 Sep 2026 | Viewed by 488 | Submission Open

Keywords: honey; propolis; royal jelly; polyphenols; nutritional properties; bioactivity; analytical and isolation methods; bee pollen

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Role of Extracellular Vesicles in Immune Regulation

edited by Rachel Crossland

submission deadline 20 Sep 2026 | Viewed by 472 | Submission Open

Keywords: extracellular vesicle; immune regulation; immunomodulation; antigen presentation; inflammation; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

New Advances in Natural Product Synthesis and Emerging Biotechnology Applications

edited by Katarzyna Kotwica-Mojzych

submission deadline 20 Sep 2026 | Viewed by 471 | Submission Open

Keywords: natural compounds; natural product synthesis; chemical analysis; molecular technologies; biotechnology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Nasopharyngeal Carcinoma Immunology, Epigenetics, and Therapy

edited by

Wei Dai

submission deadline 20 Sep 2026 | Viewed by 464 | Submission Open

Keywords: nasopharyngeal carcinoma (NPC); epstein–barr virus (EBV); cancer epigenomics; virus–host interaction; tumor microenvironment (TME); immunotherapy; targeted therapy; biomarker; metastasis; radiotherapy resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Animal Nutrition and Muscle Biology

edited by Usuk Jung

submission deadline 20 Sep 2026 | Viewed by 463 | Submission Open

Keywords: animal nutrition; metabolic regulation; molecular biology; molecular mechanisms; skeletal muscle; intramusculuar fat; skeletal muscle fibrosis

(This special issue belongs to the Section Molecular Biology)

Theranostic Application of Reactive Oxygen Species-Sensitive Nanocarriers

edited by

Young-Il Jeong

submission deadline 20 Sep 2026 | Viewed by 460 | Submission Open

Keywords: ROS generation; ROS detection; ROS-sensitive nanoparticles; Photodynamic therapy (PDT)

(This special issue belongs to the Section Molecular Nanoscience)

Advanced Composite Materials: Molecular Design and Applications

edited by Fan Yang

submission deadline 20 Sep 2026 | Viewed by 457 | Submission Open

Keywords: multifunctional applications; mechanical and physical properties; extreme environments; molecular dynamics analysis; composite molecular design, preparation, simulation, and characterization

(This special issue belongs to the Section Materials Science)

Immune Microenvironment and Tissue Remodeling in Oral Diseases and Oral Cancer

edited by

Aiman Ali

submission deadline 20 Sep 2026 | Viewed by 454 | Submission Open

Keywords: immune microenvironment; oral cancer; oral diseases; tissue remodeling; molecular signaling pathways

(This special issue belongs to the Section Molecular Immunology)

Molecular Perspectives on Female Infertility and Fertility

edited by

Seung-Yup Ku

submission deadline 20 Sep 2026 | Viewed by 438 | Submission Open

Keywords: female infertility; molecular mechanisms of reproduction; oocyte maturation and development; reproductive aging; polycystic ovary syndrome; endometriosis; epigenetic regulation in reproduction; oxidative stress and mitochondrial dysfunction; reproductive biomarkers; precision medicine and regenerative therapies

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Polymer Materials Related to Food Packaging

edited by

Rosie Yagmur Yegin

submission deadline 20 Sep 2026 | Viewed by 434 | Submission Open

Keywords: polymeric materials; food packaging; biodegradable polymers; active packaging; intelligent packaging; nanocomposites; sustainability; circular economy; barrier properties; life cycle assessment

(This special issue belongs to the Section Macromolecules)

Down Syndrome: From Molecular Mechanisms to Therapeutic Strategies

edited by Amy Feldman Lewanda

submission deadline 20 Sep 2026 | Viewed by 433 | Submission Open

Keywords: down syndrome; Trisomy 21; molecular mechanisms; therapeutic strategies; neurodegeneration; comorbidities; animal models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Neuroprotective Phytochemicals and Their Multi-Target Mechanisms

edited by

Gerardo Álvarez-Rivera

and

Alejandro Cifuentes

submission deadline 20 Sep 2026 | Viewed by 432 | Submission Open

Keywords: Alzheimer’s disease; neuroprotective phytochemicals; green extraction; technologies; blood–brain barrier permeability; bioavailability; multi-target mechanisms; omics approaches; nanodelivery systems; brain health; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Strategies for Enhancing Skeletal Muscle Recovery and Regeneration in Health and Disease Conditions

edited by

Elen Miyabara

and

Atsushi Asakura

submission deadline 20 Sep 2026 | Viewed by 432 | Submission Open

Keywords: skeletal muscle; regeneration; muscle wasting; aging; muscle diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Skin Diseases: From Molecular Mechanisms to Pathology, 2nd Edition

edited by

Alessandro Terrinoni

submission deadline 20 Sep 2026 | Viewed by 398 | Submission Open

Keywords: skin diseases; immunology; genetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Products and Compounds in Anticancer Drug Discovery

edited by

Diana I. Ivanova

submission deadline 20 Sep 2026 | Viewed by 396 | Submission Open

Keywords: antitumor plant compounds; antitumor plant-derived products; cellular pathways for natural drug apoptosis induction; chromatography of antitumor plant metabolites; modern technologies for recovery of plant anticancer substances; nanotechnology based natural anticancer drug products; plant-derived antitumor drug-protein interactions

(This special issue belongs to the Section Molecular Pharmacology)

Nutrition from Cereal Foods: Molecular Insights into Nutrition, Metabolism and Health Regulation

edited by Genyi Zhang

submission deadline 20 Sep 2026 | Viewed by 395 | Submission Open

Keywords: molecular breeding; cereal crops; bioactive compounds; metabolic syndrome; inflammation; gut health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Optical, Raman, and Pathological Imaging Biomarkers for Diagnosis and Therapy

edited by

Yoshinori Harada

submission deadline 20 Sep 2026 | Viewed by 393 | Submission Open

Keywords: optical imaging; Raman spectroscopy; pathological imaging; imaging biomarkers; AI-assisted diagnosis; disease prognosis; therapeutic response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Identification and Analysis of Interspecies Interactions in Microbial Biofilms

edited by

Terence L. Marsh

submission deadline 20 Sep 2026 | Viewed by 383 | Submission Open

Keywords: biofilm; interspecies communication; biofilm demographics; competition; commensalism; parasitism; mutualism; methodologies

(This special issue belongs to the Section Molecular Microbiology)

Interactions Between Nanoparticles and Biomolecules

edited by

Zhengwei Huang

submission deadline 20 Sep 2026 | Viewed by 380 | Submission Open

Keywords: nanoparticle–biomolecule interaction; nanomedicine; bio-corona; targeting; in vivo fate

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights into Serotonin

edited by Joachim Neumann

submission deadline 20 Sep 2026 | Viewed by 378 | Submission Open

Keywords: serotonin; serotonin receptors; migraine; depression; hypertension; heart failure; arrhythmias

(This special issue belongs to the Section Molecular Biology)

Drug Discovery and Preclinical Pharmacology for Cognitive and Neuropsychiatric Disorders in Aging

edited by

Malgorzata Zaremba

submission deadline 20 Sep 2026 | Viewed by 376 | Submission Open

Keywords: aging brain; neural aging; neurodegeneration; neuropsychiatric disorders; late-life psychiatric disorders; dementia syndromes

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Regulation of Glycoproteins in Cancer Biology

edited by

Josiah Ochieng

submission deadline 20 Sep 2026 | Viewed by 375 | Submission Open

Keywords: glycoprotein; metastasis; glycosylation; tumor progression

(This special issue belongs to the Section Molecular Biology)

Effects of Natural Products on Neurological Diseases

edited by

Maytal Shabat-Simon

submission deadline 20 Sep 2026 | Viewed by 370 | Submission Open

Keywords: natural products; neurodegenerative diseases; oxidative stress; neuroinflammation; amyloid β; TAU pathology; PI3K/AKT; BDNF-TrkB-CREB; phytochemicals; neuroprotection; cannabinoids; psilocybin/psilocyn; mitochondrial dysfunction; blood–brain barrier; high-throughput screening; animal models; structure–activity relationship; pharmacokinetics; bioavailability

(This special issue belongs to the Section Molecular Neurobiology)

Epigenetic and Transcriptional Regulation in Aquaculture

edited by

Chan-Hee Kim

submission deadline 20 Sep 2026 | Viewed by 368 | Submission Open

Keywords: epigenetics; transcriptional regulation; trained immunity; DNA methylation; histone modifications; non-coding RNAs; disease prevention; aquaculture

(This special issue belongs to the Section Molecular Genetics and Genomics)

Non-Coding RNAs, Alarmins, Protein Dynamics, and Therapeutic Targets in Diseases

edited by

Alessandra Magenta

and

Elena Dellambra

submission deadline 20 Sep 2026 | Viewed by 362 | Submission Open

Keywords: non-coding RNAs; alarmins; protein dynamics; therapeutic intervention; inflammatory; cancer; cardiovascular diseases; neurodegenerative diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Gestational Diabetes Mellitus: 2nd Edition

edited by Natasha Singh

submission deadline 20 Sep 2026 | Viewed by 356 | Submission Open

Keywords: metabolome; placental insulin signaling; DNA methylation; mitochondrial oxidation; MTOR; amino acids lipidomics; proteomics; gluconeogenesis; GDM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exopolysaccharides of Microbial Origin: Production, Analysis and Modification

edited by Marzena Jedrzejczak-Krzepkowska and

Karolina Ludwicka

submission deadline 20 Sep 2026 | Viewed by 350 | Submission Open

Keywords: exopolysaccharide; biopolymer; biofilm; microorganism; biosynthesis; genetic engineering; molecular design; modification; analysis

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Supramolecular Structure

edited by Massoud Kaykhaii

submission deadline 20 Sep 2026 | Viewed by 349 | Submission Open

Keywords: supramolecular chemistry; molecular self-assembly; host–guest interactions; molecular recognition; non-covalent interactions; dynamic supramolecular systems; stimulus-responsive materials; nanostructures; supramolecular therapeutics; structural characterization

(This special issue belongs to the Section Materials Science)

Molecular Basis of Proteinopathies in Neurodegenerative Diseases

edited by

Kyoung Joo Cho

submission deadline 20 Sep 2026 | Viewed by 334 | Submission Open

Keywords: protein misfolding; neurodegenerative diseases; protein aggregation; proteostasis; post-translational modifications; ubiquitin–proteasome system; autophagy; targeted protein degradation; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Applications of Photodynamic Therapy in Cancer

edited by

Natalia Belén Rumie Vittar

submission deadline 20 Sep 2026 | Viewed by 329 | Submission Open

Keywords: tumor microenvironment; CAF; hypoxia; immune evasion; combined therapies; new cellular or molecular targets

(This special issue belongs to the Section Molecular Oncology)

Next-Generation Drug Development: Novel Modalities, AI Modeling, and Biomarkers

edited by

Chun-Yi Wu

submission deadline 20 Sep 2026 | Viewed by 326 | Submission Open

Keywords: pharmacokinetics; PK/PD modeling; biologics; antibody–drug conjugates (ADCs); biomarkers; artificial intelligence; novel therapeutic modalities; precision medicine

(This special issue belongs to the Section Molecular Pharmacology)

Updates on Human Embryonic Stem Cells

edited by

Yoon Young Kim

submission deadline 20 Sep 2026 | Viewed by 321 | Submission Open

Keywords: human embryonic stem cells; pluripotent stem cells; differentiation; pluripotency; cell-based therapy; embryo; disease modeling

(This special issue belongs to the Section Molecular Biology)

Advancements in the Electrochemical Detection of Biomolecules: From Sensing to Environmental Applications

edited by

Habibulla Imran

submission deadline 20 Sep 2026 | Viewed by 310 | Submission Open

Keywords: biomolecules; nanomaterials; biorecognition; biomolecular detection; electrochemical

(This special issue belongs to the Section Molecular Biophysics)

Nano-Enabled Molecular Strategies Against Oxidative Stress in Human Physiology

edited by

Ali Amer

submission deadline 20 Sep 2026 | Viewed by 307 | Submission Open

Keywords: nanoparticles; oxidative stress; reproductive toxicology; redox signalling pathways; mitochondrial regulation; controlled drug release; antioxidant defence mechanisms; pharmaceutical nanotechnology

(This special issue belongs to the Section Molecular Immunology)

Obesity and Cancer: Molecular, Cellular and Systemic Mechanisms Underlying Tumor Initiation, Progression and Prognosis

edited by

María Herranz-López

and

María Losada Echeberría

submission deadline 20 Sep 2026 | Viewed by 296 | Submission Open

Keywords: obesity; cancer metabolism; tumor microenvironment; adipose tissue; adipokines; inflammation; insulin resistance; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

Molecular Developments in the Diagnosis and Treatment of Cerebral Gliomas

edited by

Alejandro N. Santos

submission deadline 20 Sep 2026 | Viewed by 296 | Submission Open

Keywords: glioma; molecular profiling; liquid biopsy; radiogenomics; tumor microenvironment; immuno-therapy; targeted therapy; blood–brain barrier; biomarkers; precision oncology

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Diagnosis and Treatment of Oral Cancer

edited by

Evila da Silva Lopes Salles

submission deadline 20 Sep 2026 | Viewed by 285 | Submission Open

Keywords: oral cancer; molecular diagnosis; immunophysiology; tumor microenvironment; drug resistance; oral microbiome

(This special issue belongs to the Section Molecular Oncology)

Ameliorating Effect of Natural Bioactive Compounds on Metabolic Diseases and Their Underlying Molecular Mechanisms

edited by Baojun Xu

submission deadline 20 Sep 2026 | Viewed by 280 | Submission Open

Keywords: metabolic diseases; natural bioactive compounds; molecular mechanism; phytochemicals; curing targets; signaling pathway

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Long Non-Coding RNAs in Cancer Metastasis and Drug Resistance

edited by

Tulasigeri M. Totiger

submission deadline 20 Sep 2026 | Viewed by 275 | Submission Open

Keywords: long non-coding RNAs (lncRNAs); cancer metastasis; drug resistance; epithelial–mesenchymal transition (EMT); tumor microenvironment; chemoresistance mechanisms; RNA-based therapeutics; gene regulation; functional genomics; biomarkers in cancer

(This special issue belongs to the Section Molecular Oncology)

RNA Structure and Regulation in Biological Processes

edited by Changrui Lu

submission deadline 20 Sep 2026 | Viewed by 245 | Submission Open

Keywords: RNA structure; RNA three-dimensional conformation; RNA dynamics; RNA chemical modifications; structural biology; RNA–protein interactions; RNA structures in plant disease resistance; viral RNA structure and function; computational structure prediction; host–pathogen interactions

(This special issue belongs to the Section Biochemistry)

Cardiovascular Disease: Molecular Basis and Treatment Strategies

edited by Arrigo Cicero and

Federica Fogacci

submission deadline 20 Sep 2026 | Viewed by 225 | Submission Open

Keywords: cardiovascular disease; molecular mechanisms; atherosclerosis; endothelial dysfunction; inflammation; fibrosis; vascular aging; omics; biomarkers; microRNA; extracellular vesicles; precision cardiology; RNA therapeutics; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 351-400 on page 8 of 62.

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