Applications of Photodynamic Therapy in Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 3
Special Issue Editor
Interests: tumor microenvironment; combination therapies; immune evasion
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will explore recent advances in photodynamic therapy (PDT), with a particular emphasis on its interplay with the tumor microenvironment and its potential to uncover novel therapeutic targets. A deeper understanding of the tumor microenvironment is crucial to comprehensively validate PDT as an anticancer strategy, especially considering its influence on treatment response and resistance. We welcome contributions employing advanced in vitro models—such as 3D cultures or co-culture systems—that more accurately recapitulate cellular interactions within the tumor microenvironment, allowing for a more physiologically relevant evaluation of PDT efficacy, ideally complemented by in vivo validation. Studies addressing mechanisms of immune evasion and how these impact PDT outcomes are also of high interest, as are investigations into innovative combination therapies aimed at overcoming therapeutic resistance. Furthermore, we aim to highlight research that leverages PDT to identify and validate new molecular or cellular targets within the tumor context, ultimately contributing to more precise and effective cancer treatments.
Dr. Natalia Belén Rumie Vittar
Guest Editor
Manuscript Submission Information
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Keywords
- tumor microenvironment
- CAF
- hypoxia
- immune evasion
- combined therapies
- new cellular or molecular targets
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