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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms Study of Functional Foods and Nutrients in Human Health Interventions

edited by

Rui Jiao

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2797 | Submission Open

Keywords: functional foods; molecular mechanisms; nutrient bioavailability; chronic disease prevention; health interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nucleic Acid Recognition and Pharmaceutical Ligand Design

edited by

Marijana Radić Stojković

and

Atanas Kurutos

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2690 | Submission Open

Keywords: nucleic acid recognition; ligand design; analytical techniques; computational chemistry; therapeutics

(This special issue belongs to the Section Macromolecules)

Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications

edited by

Daniel José Barbosa

and

Renata Silva

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2678 | Submission Open

Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies

(This special issue belongs to the Section Molecular Neurobiology)

Aging: From Molecular Mechanisms and Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Darío Acuña-Castroviejo

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2675 | Submission Open

Keywords: human aging; molecular clock; aging genes; epigenetics; nutrigenomics; inflammaging; stem cells; telomeres; mitochondria; brain-gut axis; brain-muscle axis; gut microbiota; chronodisruption

(This special issue belongs to the Section Molecular Biology)

Drugs—from Chemical Structure to Biological Activity

edited by

Sravani Sana

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2631 | Submission Open

Keywords: hit molecule; lead optimization; drug design; virtual screening; molecule descriptors; structure– activity relationship; pharmacokinetic/ADME profile; in vitro biological activity

(This special issue belongs to the Section Molecular Pharmacology)

Towards Complex Molecular Cancer Therapies

edited by

Luba Hunáková

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2608 | Submission Open

Keywords: precision medicine; immune system harnessing; targeted therapies TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Immune Response to Virus Infection and Vaccines

edited by

Giulia Matusali

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2583 | Submission Open

Keywords: immunogenicity; emerging pathogen vaccination; molecular and cellular determinants of vaccine responses in immunocompromised individuals; predictive markers of immune response; laboratory methods to dissect immune responses to infections and vaccinations

(This special issue belongs to the Section Molecular Immunology)

Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes

edited by

Eugenio Luigi Iorio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2542 | Submission Open

Keywords: redox systems; aging and disease; nutraceuticals; probiotics; animals; plants; aquatic ecosystems; microbiomes

(This special issue belongs to the Section Molecular Biology)

Editorial Board Member's Collection Series: The Memory of the Immune Cells

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2494 | Submission Open

Keywords: immunological memory; innate immune memory; dendritic cells; natural killer cells; macrophage memory

(This special issue belongs to the Section Molecular Immunology)

Elucidating How Chondrocytes Maintain Cartilage Stability

edited by James A. Martin

submission deadline 20 Feb 2026 | 4 articles | Viewed by 2463 | Submission Open

Keywords: chondrocytes; articular cartilage; chondrogenesis; osteoarthritis; mechano-transduction; aging; extracellular matrix

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2462 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Viral Vector-Mediated Genome Editing Therapy

edited by

Izumu Saito

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2392 | Submission Open

Keywords: genome editing; adenovirus vector; knock-in; inherited disease; viral vectors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2380 | Submission Open

Keywords: bone; stem cells; immunomodulation; biomaterials; bone regeneration; bone repair; bone diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Intestinal 3D Culture, Organoids and Gut-on-Chip in Intestinal Disorders

edited by

Vanessa D’Antongiovanni

and

Carolina Pellegrini

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2363 | Submission Open

Keywords: 3D cultures; gut-on-chip; intestinal organoids; spheroids; organotypic cultures; morphological studies; pharmacological studies; intestinal cancer; inflammatory bowel disease; intestinal functional disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Adsorbing Materials

edited by Mounia Achak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2315 | Submission Open

Keywords: adsorption process; adsorbing materials; bio-based adsorbents; regeneration and reusability; pollutant removal; wastewater treatment; industrial and environmental applications

(This special issue belongs to the Section Materials Science)

Molecular Biology of Lung Cancer: From Intrinsic to Acquired Resistance Mechanisms

edited by

Federico Pio Fabrizio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2287 | Submission Open

Keywords: lung cancer; NSCLC; cancer therapy; resistance; DNA methylation

(This special issue belongs to the Section Molecular Oncology)

Molecular Associations Between Adipose Tissue and Diseases

edited by

Roberto Cannataro

Erika Cione

and

Maria Cristina Caroleo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2260 | Submission Open

Keywords: lipedema; adipose tissue; adipocyte; adipose organ; body fat; miRNA; ketogenic diet

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Environmental Heavy Metals with Their Benefits and Risks for Human Health

edited by

Rolf Teschke

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2254 | Submission Open

Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis

(This special issue belongs to the Section Molecular Toxicology)

Pathophysiological Insights, Biomarkers and New Therapeutic Strategies in Immune-Mediated Disorders and Neurodegenerative Diseases

edited by

Eleonora Virgilio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2224 | Submission Open

Keywords: neurodegeneration; neuroimmunology; inflammation; biomarkers; treatment; pathophysiology; multiple sclerosis; myasthenia gravis; neurodegenerative disease

(This special issue belongs to the Section Molecular Immunology)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2185 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2174 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights into the Antibacterial Effect of Nano- and Micro-Materials

edited by

Krasimir Vasilev

and

Vi Khanh Truong

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2168 | Submission Open

Keywords: antibacterial coatings; biomaterials; medical devices; antimicrobial resistance; nanomedicine

(This special issue belongs to the Section Materials Science)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2123 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Functions of Extracellular Vesicles

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2121 | Submission Open

Keywords: extracellular vesicles; molecular mechanisms; biomarkers; liquid biopsy; cell-communication; cellular function; pathobiology; clinical

(This special issue belongs to the Section Molecular Biology)

The Impact of Biomolecules on the Pathogenesis of Oral and Periodontal Diseases

edited by

Ujjal Kumar Bhawal

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2093 | Submission Open

Keywords: biomolecules; inflammatory mediators; enzymes; cytokines; dysbiosis; microbiome; genetic and epigenetic factors; oral and periodontal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2032 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2023 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Therapeutic Targets in Cardiometabolic Disorders

edited by Massimiliano M. Corsi Romanelli and

Pietro Formisano

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1988 | Submission Open

Keywords: atherosclerosis; angiotensin; endothelial cell; inflammation; biomarkers; gLP-1; sT-2

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Protein Kinase in Disease, 2nd Edition

edited by

Manae Suzuki Kurokawa

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1977 | Submission Open

Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Diagnosis and Treatment of Migraine

edited by

Fabiola Dach

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1923 | Submission Open

Keywords: migraine; pathophysiology; diagnostics; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Heart Failure: From Bench to Bedside

edited by

Nadia Aspromonte

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1875 | Submission Open

Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Pathogenesis and Treatment of Skin Cancer (2nd Edition)

edited by

Enrica Flori

Giorgia Cardinali

and

Vittoria Maresca

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1781 | Submission Open

Keywords: melanoma; squamous cell carcinoma; basal cell carcinoma; tumor microenvironment; epithelial– mesenchymal transition (EMT) process; ultraviolet radiation; oxidative stress; bioactive modulators; signal transduction pathways

(This special issue belongs to the Section Molecular Oncology)

Plant Metabolism and Natural Product Biosynthesis

edited by

Andrej Frolov

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1775 | Submission Open

Keywords: plant metabolism; natural product; biosynthesis; metabolomics; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Phytochemicals in Antioxidation, Antimicrobial, and Cytoprotective Properties

edited by

Mihaela Niculae

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1774 | Submission Open

Keywords: phytochemicals; antioxidant; antimicrobial; cytoprotective; in vitro screening; in vivo evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches

edited by

Bin Yang

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1768 | Submission Open

Keywords: kidney injury; repair; immunoresponse; biomarker; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Genetics in Rare Diseases: A Genomic Odyssey

edited by

Klaus Brusgaard

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1756 | Submission Open

Keywords: novel discoveries in rare disorders; polygenic risk scores; mosaicism; protein interaction; tools utilized to engineer DNA; somatic variants; patient advocacy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1725 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Developing Chiral Products: New Progression in Separation, Synthesis, and Application

edited by István Ilisz

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1716 | Submission Open

Keywords: chirality; enantioselective separations; chiral selector molecules; chiral stationary phases; chiral sensors; enantiorecognition; chiral separation mechanisms

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Diversity of Life: Light to Heavy Metal Coordination Compounds of Biological Relevance

edited by

Ivayla Pantcheva

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1701 | Submission Open

Keywords: coordination compounds; metal-based drugs; antimicrobial; anti-inflammatory; antiviral agents; cancer therapy; drug delivery systems

(This special issue belongs to the Section Biochemistry)

New Advances in Cystinosis from Basic to Clinical Research

edited by Francesco Bellomo

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1670 | Submission Open

Keywords: cystinosis; kidney; Fanconi syndrome; muscles; eyes; autophagy; bioenergetics; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ruminant Physiology: Digestion, Metabolism, and Endocrine System

edited by Rui Hu

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1637 | Submission Open

Keywords: ruminant physiology; digestive health; metabolic regulation; endocrine signaling; rumen microbiome; nutrient partitioning; methane mitigation; epigenetic modulation; nutritional stress adaptation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Toxicological Impacts of Emerging Contaminants on Aquatic Organisms

edited by

Mohamed Hamed

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1608 | Submission Open

Keywords: aquatic toxicology; emerging contaminants; physiology and behavior; oxidative stress; antioxidant biomarkers; immunotoxicity; neuroendocrine toxicity; bioremediation; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Advancing Liver Health: State of the Art and Recent Research Advances

edited by

Chase Wehrle

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1569 | Submission Open

Keywords: liver; liver cancer and malignancy; liver transplantation; inflammation and immunity; liver health and ageing; molecular genomics; cellular senescence; metabolic dysfunction-associated liver disease; cirrhosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gynecological Oncology: From Molecular Basis to Therapy

edited by

Martin Götte

and Lars Hanker

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1544 | Submission Open

Keywords: gynecological oncology; molecular basis; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology of Periodontal Disease and Periodontal Pathogens

edited by Yago Leira and

João Botelho

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1534 | Submission Open

Keywords: periodontitis; general medicine; inflammation; bacteraemia; education

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Natural Compounds in Neuroscience

edited by

Sarmistha Mitra

submission deadline 20 Feb 2026 | Viewed by 1525 | Submission Open

Keywords: natural products; bioactive metabolites; secondary metabolites; neuronal development; neurotrophins; neuromedicine; neurodegeneration; memory disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into the Role of Exercise in Disease and Health, 2nd Edition

edited by

Brisamar Estébanez

, María José Cuevas-González and Chun-Jung Huang

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1523 | Submission Open

Keywords: physical activity; molecular mechanisms; disease prevention; metabolic health; cardiovascular diseases; neurodegenerative diseases; sarcopenia; immune function; healthy aging; epigenetics

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Tumorigenesis of Human and Animal Stem Cells

edited by

Daniela Salvatori

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1512 | Submission Open

Keywords: malignancy; stem cells; safety; chromosal aberrations; animal; human; teratoma assay; in vitro assays

(This special issue belongs to the Section Molecular Oncology)

Research on Alloy Materials Microstructure and Their Functionalization

edited by

Ozkan Gokcekaya

and Celaletdin Ergun

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1508 | Submission Open

Keywords: alloy design; microstructure; production methods; additive manufacturing; sol– gel process; biofunctional materials; magnetic properties; nanoparticles; ceramics; composites

(This special issue belongs to the Section Materials Science)

Molecular Research on Parasitic Infection

edited by Marcin Wiśniewski and

Piotr Bąska

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1433 | Submission Open

Keywords: parasitic infections; host– parasite interactions; parasite genomics; drug-resistance mechanisms; transcriptomics; proteomics; diagnostic tools; immune evasion; therapeutic strategies

(This special issue belongs to the Section Molecular Microbiology)

Displaying special issue 1451-1500 on page 30 of 65.

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