Translational Pharmacogenomics and Precision Medicine: From Discovery to Application
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 78
Special Issue Editor
Interests: personalized medicine; pharmacogenomics; cancer research; hemoglobinopathies (beta-thalassemia, sickle cell anemias); drug identification; drug discovery; nutrigenomics; wellness genetics; population screening of genetic disorders; RNAi; microbiota
Special Issue Information
Dear Colleagues,
By providing customized therapeutic and preventive interventions based on individual genetic profiles, translational pharmacogenomics and precision medicine are revolutionizing modern healthcare. The incorporation of pharmacogenomic data into clinical decision-making has been expedited by advances in genomic technologies, especially in cancer research including oral cancers, where genetic characterization of tumors has resulted in tailored medicines with enhanced efficacy and decreased toxicity. Similarly to this, new therapeutic methods and early diagnosis through population-based screening programs are being guided by genetic discoveries in dentistry and inherited blood illnesses such as sickle cell anemia and beta-thalassemia. Finding new molecular targets and creating safer, more potent treatments are being made easier by the integration of pharmacogenomics and drug discovery. Researchers can create precision medications and improve dosage techniques by understanding genetic variances that affect the microbiome, drug metabolism, efficacy, and side effects. Nutrigenomics, which examines the relationship between genes, nutrition, and health outcomes, is developing concurrently as a supplementary subject. This area of study adds to the larger framework of wellness genetics by assisting in the creation of customized diet regimens targeted at illness prevention and general wellness.
In order to identify gene functions and validate therapeutic targets, high-throughput technologies such as RNA interference-based screening and quantitative gene expression analysis are essential. These approaches improve the results of translational research by facilitating the methodical examination of gene networks and their role in disease pathways. Large-scale genomic screening programs are also lowering the burden of disease and facilitating prompt interventions by enhancing the early detection and management of genetic abnormalities at the population level. All of these developments highlight how crucial it is to include genomics in healthcare systems in order to provide more accurate, predictive, and preventive treatment. Pharmacogenomics, nutrigenomics, crosstalk with the microbiome, and translational research hold great potential to improve patient outcomes and influence personalized treatment in the future.
Prof. Dr. Sukru Tuzmen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmacogenomics
- personalized medicine
- drug discovery
- cancer genetics
- wellness
- nutrigenomics
- mindfulness
- genome
- health
- dentistry
- education
- microbiome
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
