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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Development Breakthroughs: From Novel Antimicrobials to Targeted Cancer Drugs

edited by

Christos Papaneophytou

submission deadline 20 Aug 2025 | Viewed by 599 | Submission Open

Keywords: drug development; molecular science; small-molecule inhibitors; biopharmaceuticals; peptides; cancer therapy

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights and Design Strategies for Carbonaceous Nanomaterials

edited by

Magdalena Krystyjan

and

Gohar Khachatryan

submission deadline 20 Aug 2025 | Viewed by 596 | Submission Open

Keywords: carbon nanomaterials; carbon (nano)fillers; graphene; carbon nanotubes; carbon quantum dots; nanoparticles; nanostructures

(This special issue belongs to the Section Molecular Nanoscience)

New Insights into the Pathobiology of T Cell Malignancies

edited by

Grzegorz Przybylski

submission deadline 20 Aug 2025 | Viewed by 593 | Submission Open

Keywords: T cell malignancies

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in the Application of NMR Spectroscopy to Study Structure and Dynamics of Proteins

edited by Harindranath Kadavath

submission deadline 20 Aug 2025 | Viewed by 553 | Submission Open

Keywords: proteins; dynamics; NMR spectroscopy; structure– dynamics– function; protein folding; protein– protein interactions; in-cell NMR; biomolecular structure; intrinsically disordered proteins (IDPs)

(This special issue belongs to the Section Molecular Biology)

Mechanistic and Small Molecule Discoveries for Therapeutic Advances in Hypertrophic and Dilated Cardiomyopathies

edited by Osha Roopnarine

submission deadline 20 Aug 2025 | Viewed by 542 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathies; cardiomyopathies

(This special issue belongs to the Section Molecular Pharmacology)

Physiological and Molecular Mechanisms of Abiotic Stresses in Crops

edited by

Yousef Alhaj Hamoud

submission deadline 20 Aug 2025 | Viewed by 536 | Submission Open

Keywords: abiotic stress; plant physiology; signaling pathways; plant molecular biology; resistance; crop yield and quality

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Purinergic System

edited by Margarete Dulce Bagatini

submission deadline 20 Aug 2025 | 1 articles | Viewed by 493 | Submission Open

Keywords: purinergic system; receptors; ectonucleotidases; CD39; CD73; purinergic signaling

(This special issue belongs to the Section Biochemistry)

Mechanisms of Protein–Ligand Interactions in Therapies for Lifestyle Diseases and Their Complications

edited by Agnieszka Szkudlarek

submission deadline 20 Aug 2025 | Viewed by 489 | Submission Open

Keywords: chronic diseases and their complications; protein– ligand interactions; protein modifications; therapeutic efficacy; binding affinity; serum proteins; pharmaceutical applications; biomedical research

(This special issue belongs to the Section Molecular Biology)

The Role of Genome in Cancer Therapy

edited by Yoav Smith and Hovav Nechushtan

submission deadline 20 Aug 2025 | Viewed by 480 | Submission Open

Keywords: genome analysis; molecular therapy; drug resistance; cancer genetic

(This special issue belongs to the Section Molecular Genetics and Genomics)

Solanaceae Biology: From Genetics to Metabolism

edited by

Pengxiang Fan

submission deadline 20 Aug 2025 | Viewed by 459 | Submission Open

Keywords: Solanaceae; nightshade family; tomato; potato; tobacco; eggplant; genetics; metabolism; crop improvement; specialized metabolite

(This special issue belongs to the Section Molecular Plant Sciences)

Yeast Models in Genetic and Molecular Research

edited by

Ee Sin Chen

submission deadline 20 Aug 2025 | Viewed by 448 | Submission Open

Keywords: yeast; genome; epigenetics; chemogenomics; DNA repair

(This special issue belongs to the Section Molecular Biology)

Obesity and Cancer Risk: Molecular Mechanisms and Perspectives

edited by

Hendrik Lehnert

submission deadline 20 Aug 2025 | 1 articles | Viewed by 434 | Submission Open

Keywords: epidemiology of obesity and cancer; experimental models of cancer in obesity; genetic and epigenetics of obesity and metabolic dysfunction associated cancer; tumor microenvironment; basis of metastatic spread of cancer in obesity; therapeutic modeling and targeting

(This special issue belongs to the Section Molecular Oncology)

Experimental Models and Applications in Muscle Regeneration

edited by

Daiva Bironaite

submission deadline 20 Aug 2025 | Viewed by 431 | Submission Open

Keywords: stem cells; internal and external stimuli; scaffolds; signaling systems; muscle regeneration mechanisms

(This special issue belongs to the Section Molecular Biology)

Cellular Senescence as a Therapeutic Target in Cancer: Mechanisms, Challenges, and Therapeutic Opportunities

edited by

Mi Kyung Park

submission deadline 20 Aug 2025 | Viewed by 425 | Submission Open

Keywords: cellular senescence; cancer therapy; therapeutic targeting; senolytic drugs; senescence-associated secretory phenotype (SASP)

(This special issue belongs to the Section Molecular Oncology)

Cellular Senescence and the Senescence-Associated Secretory Phenotype (SASP) in Age-Related Diseases

edited by Jordi Olloquequi

submission deadline 20 Aug 2025 | Viewed by 421 | Submission Open

Keywords: cellular senescence; senescence-associated secretory phenotype (SASP); age-related diseases; atherosclerosis; chronic obstructive pulmonary disease (COPD); type 2 diabetes mellitus (T2DM); non-alcoholic fatty liver disease (NAFLD); Alzheimer’ s disease (AD); inflammation; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Impact of the Biological Clock on Health and Disease

edited by

Bojlul Bahar

submission deadline 20 Aug 2025 | Viewed by 408 | Submission Open

Keywords: circadian rhythm; inflammation; oxidative stress; energy balance; metabolic syndrome; ageing; cancer; diabetes; obesity; entrainment; synchrony; melatonin

(This special issue belongs to the Section Molecular Biology)

Insights into Neurological and Psychiatric Diseases from Invertebrate Models

edited by

Efthimios M. C. Skoulakis

submission deadline 20 Aug 2025 | Viewed by 401 | Submission Open

Keywords: disease model development; disease model validation; GWAS validation; ameliorative approaches; pharmacogenetics; pharmacoproteomics; disease mechanisms; suppressor/enhancer genetic screens; synthetic lethality screens; biomarker screens and validation

(This special issue belongs to the Section Molecular Neurobiology)

Roles of Phytochemicals in Cancer Prevention and Therapeutics: 2nd Edition

edited by

Daniel Gabriel Pons

submission deadline 20 Aug 2025 | Viewed by 400 | Submission Open

Keywords: phytochemicals; cancer prevention; cancer therapeutics; oxidative stress; inflammation; energetic metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology

edited by Richard H. W. Funk

submission deadline 20 Aug 2025 | Viewed by 394 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

Advancements and Applications of Phyto-Nanotherapy in Targeted Disease Treatment

edited by

Adewale Fadaka

and

Nicole Remaliah Samantha Sibuyi

submission deadline 20 Aug 2025 | Viewed by 381 | Submission Open

Keywords: phyto-nanotherapy; medicinal plants; nanoparticles; targeted drug delivery; phytochemicals; phytotherapy; green nanotechnology; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Heparin, Heparan Sulfate and Heparanase, 2nd Edition

edited by

Nobuaki Higashi

submission deadline 20 Aug 2025 | Viewed by 380 | Submission Open

Keywords: allergy; angiogenesis; cancer metastasis; cellular trafficking; exosome; fibrosis; glycocalyx; glycosaminoglycans; heparan sulfate; heparanase; heparin; immune responses; inflammation; inbibitor development; sepsis/SIRS (systemic inflammatory response syndrome); sulfatase; viral infections

(This special issue belongs to the Section Macromolecules)

The Role of Cannabinoids in Human Health and Disorder

edited by

Grazia Chiellini

and Beatrice Polini

submission deadline 20 Aug 2025 | Viewed by 373 | Submission Open

Keywords: cannabinoids; cannabinoid receptors; endocannabinoid system; ECS synthetic modulators; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring the Role of Antioxidants in Supplements and Drug Responses

edited by

Maria Greabu

submission deadline 20 Aug 2025 | Viewed by 372 | Submission Open

Keywords: NSAIDs; glucocorticoids; vitamin E; antioxidants; oxidative stress; inflammation

(This special issue belongs to the Section Molecular Immunology)

Roles and Functions of Micronutrients in Gut Microbiota and Intestinal Inflammation

edited by

Chao Wang

submission deadline 20 Aug 2025 | Viewed by 363 | Submission Open

Keywords: micronutrients; gut microbiota; intestinal inflammation; intestinal barrier; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Aug 2025 | 1 articles | Viewed by 342 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Fruit Crops Development

edited by

Xingguo Li

submission deadline 20 Aug 2025 | Viewed by 334 | Submission Open

Keywords: fruit crops; fruit tree; proteomics; genomics; metabolomics; biotic stress; abiotic stress

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Melatonin in Plants: 3rd Edition

edited by

Małgorzata M. Posmyk

submission deadline 20 Aug 2025 | Viewed by 332 | Submission Open

Keywords: melatonin; phytomelatonin; plants; seed germination; seasonal and circadian rhythms; flowering; fruit ripening; plant immunity; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Nanotechnology in Drug Delivery: Applications and Perspectives

edited by Ádám Juhász

submission deadline 20 Aug 2025 | Viewed by 327 | Submission Open

Keywords: nanostructured materials; drug delivery; drug– carrier interactions; hydrogel; aerogels; associated colloids; surfactants; macromolecules; blood– brain barrier; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Artificial Intelligence in Human Disease: Current and Future Perspectives in Digital Medicine

edited by

Dumache Raluca-Oana

submission deadline 20 Aug 2025 | Viewed by 316 | Submission Open

Keywords: molecular genetics; artificial intelligence; pharmacogenomics; internet of things; molecular pathology; genomic medicine

(This special issue belongs to the Section Molecular Informatics)

Genetic Mechanisms of Neurological Disorders

edited by

Patrícia Maciel

and Sara Duarte-Silva

submission deadline 20 Aug 2025 | Viewed by 316 | Submission Open

Keywords: neurodevelopmental disorders; neurodegenerative disorders; neuropsychiatric disorders; genetics; molecular biology; cellular models; animal models; pathogenesis; biomarkers; therapeutic targets; drug discovery; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammation and Metabolic Response in Mitochondrial Diseases

edited by

Guido Primiano

submission deadline 20 Aug 2025 | Viewed by 315 | Submission Open

Keywords: mitochondrial diseases; mitochondria; mtDNA; metabolic remodeling; inflammation; immunity; cell death; neurodegenration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights in Nanomaterials and Electroactive Molecules—in Memory of Prof. Royce W. Murray

edited by

Zeev Porat

submission deadline 20 Aug 2025 | Viewed by 301 | Submission Open

Keywords: nanomaterials; organic electrochemistry; macromolecules and polymers; analytical chemistry

(This special issue belongs to the Section Molecular Nanoscience)

Signaling Pathways in Neuroinflammation or Neurodegenerative Disorders

edited by

Marika Cordaro

submission deadline 20 Aug 2025 | Viewed by 298 | Submission Open

Keywords: inflammation; neuroinflammation; oxidative stress; neurodegenerative disorders; pathology; molecular pathways; dysregulation; mitochondrial dysfunction

(This special issue belongs to the Section Molecular Neurobiology)

Tumor Specific Immunotherapeutic Targets

edited by

Roberto Perris

submission deadline 20 Aug 2025 | Viewed by 294 | Submission Open

Keywords: immunotherapy; immunotherapeutics; tumour-specific antigens; immunotherapeutic targets; multi-omics approaches

(This special issue belongs to the Section Molecular Immunology)

New Insights into Hyaluronan in Human Medicine

edited by

Monica Salamone

submission deadline 20 Aug 2025 | Viewed by 291 | Submission Open

Keywords: hyaluronan; regenerative medicine; inflammation; cancer therapy; metabolomics ; hyaluronidases; cell– matrix interaction; glucose metabolism; pathological processes

(This special issue belongs to the Section Biochemistry)

Research Progress of Nanodrug Delivery System

edited by Kenta Morita

submission deadline 20 Aug 2025 | Viewed by 257 | Submission Open

Keywords: drug delivery; nanomaterials; nanomedicine; pharmacokinetics; theranostics; imaging; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Nrf1/2/3 and Other Antioxidant Transcription Factors in Health and Disease

edited by

Eleonora Stanca

submission deadline 20 Aug 2025 | Viewed by 146 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Development and Applications of Biodegradable and Bioactive Materials

edited by

Mercedes Ana Peltzer

submission deadline 20 Aug 2025 | Viewed by 73 | Submission Open

Keywords: biopolymers; bioplastics; sustainability; food packaging; medicine and cosmetic; bioactive compounds; wound healing; active and intelligent packaging

(This special issue belongs to the Section Materials Science)

Molecular Studies of Endometriosis and Associated Diseases

edited by Sarah J Holdsworth-Carson

submission deadline 21 Aug 2025 | 4 articles | Viewed by 6367 | Submission Open

Keywords: adenomyosis; autoimmune diseases; cardiometabolic conditions; endometriosis; fatigue; heavy menstrual bleeding; irritable bowel syndrome; migraine; painful bladder syndrome; pelvic floor muscle dysfunction; pelvic inflammatory disease; pelvic pain; peritoneal adhesions; polycystic ovarian syndrome; pregnancy complications; ovarian cancer; uterine fibroids

(This special issue belongs to the Section Molecular Biology)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 22 Aug 2025 | 1 articles | Viewed by 1396 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Endothelial Cells in Cancer: Molecular Advance

edited by Dae Joong Kim

submission deadline 22 Aug 2025 | Viewed by 154 | Submission Open

Keywords: tumor angiogenesis; metastasis; VEGFs; FGFs; Ang2; immune surveillance; antigen presentation; EC adhesion molecules; LYVE-1; lymphatic vessel; antigen-presenting cell; lymphocytes; high endothelial venule

(This special issue belongs to the Section Biochemistry)

New Insights into Bioactive Peptides: Design, Synthesis, Structure-Activity Relationship (2nd Edition)

edited by

Marilisa Leone

and

Flavia Anna Mercurio

submission deadline 25 Aug 2025 | 8 articles | Viewed by 11204 | Submission Open

Keywords: peptides; protein-peptide interactions; PPI inhibition and modulation; peptide drugs; peptidomimetics; cyclic peptides; stapled peptides; diagnostic peptides; peptides for drug delivery; multidisciplinary approaches TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biological Research on Plant Bioactive Compounds

edited by

Adriana Trifan

and

Simon Vlad Luca

submission deadline 25 Aug 2025 | 8 articles | Viewed by 9999 | Submission Open

Keywords: plant bioactive compounds; extraction and analysis of plant bioactive compounds; bioactivity and pharmacokinetics of plant compounds; natural products and modern diseases; plant bioactive compounds and by-products; discovery and development of natural plant drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Isolation and Biological Activities of Natural Products: Focus on Molecular Advance

edited by Pedro Ferreira and

Patricia Reboredo-Rodríguez

submission deadline 25 Aug 2025 | 3 articles | Viewed by 2056 | Submission Open

Keywords: natural products; sustainable isolation; biological activities; therapeutic potential; structure-activity relationships; omics technologies; bioavailability; functional foods; green chemistry; molecular docking

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Epilepsy: From Molecular Physiology to Pathology

edited by Paolo Mainardi

submission deadline 25 Aug 2025 | 1 articles | Viewed by 1041 | Submission Open

Keywords: epilepsy; molecular pathology; disease; therapeutic strategies; celluar advance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Terpenes: Molecular Pharmaceutics and Biotechnology

edited by Lídia Pinheiro and

Célia Faustino

submission deadline 25 Aug 2025 | Viewed by 434 | Submission Open

Keywords: terpenes; antimicrobial; anticancer; anti-inflammatory; drug discovery; drug delivery; flavours; fragrances; biofuels; biocatalysis; bioremediation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

CRISPR/Cas Systems and Genome Editing—3rd Edition

edited by

Dmitry Karpov

submission deadline 25 Aug 2025 | Viewed by 186 | Submission Open

Keywords: CRISPR/Cas; bacterial argonauts; transcription regulation; genome editing; genome editing tools

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 25 Aug 2025 | 1 articles | Viewed by 185 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Diagnosis and Treatments of Diabetes Mellitus: 2nd Edition

edited by

Mihail Virgil Boldeanu

submission deadline 25 Aug 2025 | Viewed by 170 | Submission Open

Keywords: metabolic disorders; diabetes mellitus; inflammation; neurotransmitter; inflammatory biomarkers; molecular target; molecular diagnostics; therapeutics; insulin resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Obesity: Different Perspectives Based on Molecular Physiology and Pathology

edited by Hector I. Rocha-Gonzalez

submission deadline 25 Aug 2025 | Viewed by 159 | Submission Open

Keywords: obesity; rational management; perspectives; new ideas; pharmacology; lifestyle modification; molecular advances

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 301-350 on page 7 of 69.

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