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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Radiolabeled Compounds for Theranostic Applications in Oncology

edited by

Cyril Fersing

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2988 | Submission Open

Keywords: radiopharmaceuticals; theranostic; cancer therapy; targeted radionuclide therapy; molecular imaging; positron emission tomography; single-photon emission tomography; radiolabeling

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Therapies of Gastrointestinal Cancer

edited by

Donatella Delle Cave

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2916 | Submission Open

Keywords: tumor microenvironment; therapy resistance; genetic mutations; oncogenes; molecular diagnostics

(This special issue belongs to the Section Molecular Oncology)

Systems Genetics of Metabolic Disorders: From Omics Signatures to Molecular Mechanisms

edited by

Seong-Hee Maria Ko

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2881 | Submission Open

Keywords: metabolic syndrome; single-nucleotide polymorphism (SNP); genome-wide association study (GWAS); copy number variation; diet; metabolomics; nutritional genetics; lipid metabolism; omics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Pathogenesis of Alcohol-Associated Hepatitis and Its Therapies

edited by

Mrigya Babuta

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2835 | Submission Open

Keywords: alcohol-associted hepatitis; acute kidney injury; hepatic encephalopathy; adaptive immune response; innate immune response; neutrophilia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Signatures in Overt Neurodegenerative Disease: Toward Precision Diagnosis and Classification

edited by

Jose Miguel Laffita-Mesa

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2802 | Submission Open

Keywords: neurodegenerative diseases; molecular biomarkers; disease stratification; Parkinson’s disease; Alzheimer’s disease; spinocerebellar ataxia; precision medicine; digital PCR; circRNA; prognostic biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Neurofibromatosis Type 1 and NF2-Related Schwannomatosis: Advances from Basic Research to Current Therapies

edited by

Bumjoon Park

and

Baehoon Kim

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2783 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); neurofibromin; RAS/MAPK pathway; malignant peripheral nerve sheath tumor (MPNST); NF2-related schwannomatosis (NF2 syndrome); Merlin (Schwannomin); vestibular schwannoma; meningioma; ependymoma

(This special issue belongs to the Section Molecular Neurobiology)

Nanoscience in Plants: Omics Approaches to Elucidate the Role of Nanoparticles

edited by

Setsuko Komatsu

and Zahed Hossain

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2315 | Submission Open

Keywords: nanoparticles; plant; omics-based techniques; bioinformatics; systems biology; nanotoxicology

(This special issue belongs to the Section Molecular Plant Sciences)

Electromagnetic Field Interactions with Biomolecules

edited by

Svetlana Jovanović

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2236 | Submission Open

Keywords: nonionizing electromagnetic fields; biomolecules; proteins; oxidative stress; Fe metabolism; amyloid-β peptide

(This special issue belongs to the Section Materials Science)

The Role of Non-Coding RNAs in Female Reproduction

edited by

Angela Caponnetto

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2177 | Submission Open

Keywords: microRNAs; long non-coding RNAs; circular RNAs; female reproduction; reproductive aging; molecular biomarkers; ceRNA network

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Dialogues in the Tumor Microenvironment: Mechanisms, Methods and Therapeutic Implications

edited by

José M. Muñoz-Félix

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2119 | Submission Open

Keywords: tumor microenvironment; blood vessels; immune cells; spatial transcriptomics; histology

(This special issue belongs to the Section Molecular Oncology)

Mechanisms and Innovations in Natural Killer Cell-Based Immunotherapy

edited by

Dipnarine Maharaj

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2092 | Submission Open

Keywords: natural killer cells; immunotherapy; CAR-NK; cancer therapy; adoptive cell transfer; immune modulation; tumor microenvironment; cell engineering; hematologic malignancies; viral infections

(This special issue belongs to the Section Molecular Immunology)

Cellular, Immune and Molecular Pathways of Injury and Disease in Forensic and Legal Medicine

edited by

Sorin Hostiuc

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2045 | Submission Open

Keywords: molecular autopsy; cellular injury pathways; ischemia and hypoxia markers; molecular profiling of fatal injuries; forensic genetics and toxicogenomic

(This special issue belongs to the Section Molecular Biology)

The Brain’s Regeneration Potential: The Role of Neural Progenitor Cells in Neuropsychiatric Therapy

edited by

Beatriz Caballero

and

Yaiza Potes

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2019 | Submission Open

Keywords: neural stem cells; neural progenitor cells; neuropsychiatric disorders; neurodegeneration; neurogenesis; neuroplasticity; melatonin; psychoactive drugs

(This special issue belongs to the Section Molecular Neurobiology)

Latest Advances in Gut–Brain Axis Research

edited by Qi Su

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2017 | Submission Open

Keywords: gut-brain axis; microbial metabolites; neuroinflammation; intestinal permeability; neurotransmitter; short-chain fatty acids (SCFAs); vagus nerve signaling; metabolomics

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Treatments Targeting Respiratory Diseases

edited by

Stefanie Dichtl

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1992 | Submission Open

Keywords: respiratory diseases; respiratory infections; COPD; cystic fibrosis; lung tumor; therapy; Afrikaans; Albanian; Amharic; Arabic; Armenian; Azerbaijani; Bengali; Bulgarian; Catalan; Croatian; Czech; Danish; Dutch; English; Estonian; Finnish; French; German; Greek; Gujarati; Haitian Creole; Hebrew; Hindi; Hungarian; Icelandic; Indonesian; Italian; Japanese; Kannada; Kazakh; Khmer; Korean; Kurdish (Kurmanji); Lao; Latvian; Lithuanian; Malagasy; Malay; Malayalam; Maltese; Maori; Marathi; Myanmar (Burmese); Nepali; Norwegian; Pashto; Persian; Polish; Portuguese; Punjabi; Romanian; Russian; Samoan; Simplified Chinese; Slovak; Slovenian; Spanish; Swedish; Tamil; Telugu; Thai; Traditional Chinese; Turkish; Ukrainian; Urdu; Vietnamese; Welsh

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Pathways Involved in Toxicant-Induced Stress

edited by

Maria Giulia Lionetto

and

Maria Elena Giordano

submission deadline 31 Jul 2026 | 3 articles | Viewed by 1976 | Submission Open

Keywords: oxidative stress; cell death; biomarkers; toxicant exposure; environmental toxicology; cell signaling pathways

(This special issue belongs to the Section Molecular Toxicology)

Microbial Omics: Decoding Microbial Life

edited by

Nicole Hansmeier

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1923 | Submission Open

Keywords: omics technologies; omics methodologies; microorganisms; proteomics; genomics; transcriptomics; bioinformatics, artificial intelligence for omics; microbial physiology; microbial adaptation to environmental challenges; interspecies and host-microbe interactions; environmental monitoring

(This special issue belongs to the Section Molecular Microbiology)

New Computational Methodologies for Biomolecule Sequence, Structure and Function Discovery: 2nd Edition

edited by Fei Guo

submission deadline 31 Jul 2026 | 3 articles | Viewed by 1922 | Submission Open

Keywords: bioinformatics; machine learning; deep learning; biomolecule identification; biological networks; structural proteomics; gene expression analysis; molecular docking; post-translational modifications

(This special issue belongs to the Section Molecular Informatics)

Physiology and Molecular Biology of Plant Stress Tolerance: 3rd Edition

edited by

Deguo Han

submission deadline 31 Jul 2026 | 3 articles | Viewed by 1835 | Submission Open

Keywords: plant–pathogen interactions; biotic and abiotic stress; plant innate immunity; phytohormones; genes

(This special issue belongs to the Section Molecular Plant Sciences)

The Impact of the Immune System on the Tumor Microenvironment: Relevance to Glioma Development

edited by Gabriela Verónica Salamone

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1735 | Submission Open

Keywords: gliomas
tumor microenvironment
immune

(This special issue belongs to the Section Molecular Oncology)

Cell–Cell Communication Through Extracellular Vesicles

edited by

Federica Fratini

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1621 | Submission Open

Keywords: EV biomarkers; EV biogenesis; EV drug delivery; EV trafficking; EV immuno escape

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms Behind Plant–Virus Interactions: Pathogenesis and Defense

edited by

Katarzyna Otulak-Kozieł

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1577 | Submission Open

Keywords: plant viruses; plant resistance; plant signaling; plant defense; biotic stress; plant–virus interactions; molecular mechanism

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on PRDM Genes

edited by

Erika Zazzo

Ciro Abbondanza

and

Monica Rienzo

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1538 | Submission Open

Keywords: PRDM; cancer; gene expression regulation; epigenetic modifications; proliferation; differentiation; gene expression regulation; apoptosis; cancer biomarkers; cancer diagnosis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Computer-Aided Drug Discovery: Computational Chemistry and Cheminformatics

edited by

Daniel Glossman-Mitnik

submission deadline 31 Jul 2026 | 3 articles | Viewed by 1519 | Submission Open

Keywords: computer-aided drug discovery; computational chemistry; cheminformatics; conceptual density functional theory (CDFT); molecular docking; molecular dynamics simulations; QSAR/QSPR modeling; ADMET prediction; machine learning in drug design

(This special issue belongs to the Section Molecular Informatics)

Molecular and Genomic Basis of Viral Variation and Host Adaptation

edited by In Ohk Ouh

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1500 | Submission Open

Keywords: viral genome evolution mutation and selection dynamics; structure–function relationships of viral proteins; immune evasion; regulatory mechanisms; comparative viral genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Forensics at Trial

edited by

Guido Viel

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1473 | Submission Open

Keywords: forensic science; molecular biology; evidence; proof; justice; trial; forensic pathology; forensic genetics; forensic histology; forensic toxicology

(This special issue belongs to the Section Molecular Toxicology)

Molecular Pathogenesis and Novel Therapeutic Targets in Oncologic Cardiotoxicity

edited by

Marco Tana

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1453 | Submission Open

Keywords: cardiotoxicity; CTRCD; heart failure; HFrEF; HFpEF

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Lipids in Health and Diseases: 2nd Volume

edited by

Yutang Wang

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1418 | Submission Open

Keywords: lipids; triglycerides; phospholipids; cholesterol; sphingolipids; steroids; fatty acids; lipid metabolism

(This special issue belongs to the Section Biochemistry)

Pathogenesis and Molecular Therapy of Inflammatory Bowel Disease

edited by

Anoop Kumar

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1366 | Submission Open

Keywords: intestinal epithelial barrier; gut microbiota; tight junctions; inflammatory bowel disease; mucosal immunity; autophagy; epithelial restitution; host–microbe interaction; barrier dysfunction; gastrointestinal inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights in Neuro-Ophthalmology

edited by

Toshiyuki Oshitari

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1362 | Submission Open

Keywords: neuroprotection; neurodegeneration; neuronal cell death; regeneration; cell death and survival pathways; neurovascular unit; oxidative stress; inflammation; advanced glycation end products; ischemia; optic nerve injuries; glaucoma; optic neuritis; retinitis pigmentosa; diabetic retinopathy; age-related macular degeneration; retinal vein/artery occlusion; gene therapy; cell plantation; nutrients; neuroprotectants; drug delivery; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Natural Product and Enzyme Inhibition for Disease Management

edited by

Viet Phong Nguyen

and

Le Ba Vinh

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1342 | Submission Open

Keywords: bioactive compounds; natural sources; enzyme inhibition; drug discovery; cancer; cardiovascular diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Liver Transplantation: Pathogenesis, Therapeutic Strategies and Future Challenges

edited by

Francesco Tandoi

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1334 | Submission Open

Keywords: MASLD; transplant oncology; machine perfusion; extended-criteria donors; donors after cardiac death

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autoimmune Disorders: Molecular Mechanisms and Therapeutic Strategies

edited by

Katarzyna Romanowska-Próchnicka

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1319 | Submission Open

Keywords: molecular mechanisms; immune signaling pathways; targeted therapies; biomarkers; autoimmune pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genomic and Proteomic Advances in Tracking Antibiotic Resistance Evolution

edited by

Vanessa Natália dos Santos Silva

submission deadline 31 Jul 2026 | Viewed by 1306 | Submission Open

Keywords: antibiotic resistance; genomic; proteomic; one health

(This special issue belongs to the Section Molecular Biology)

Physiology and Pathophysiology of Neurodegeneration: New Insights and Advances from Molecular to Cellular Level

edited by

Alessandro Romano

and

Amilcare Barca

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1210 | Submission Open

Keywords: central and peripheral nervous systems; neuron homeostasis; neurodegeneration; neurodegenerative disease; neurophysiology; -omic technologies; induced pluripotent stem cell (iPSC); three-dimensional cell culture; organ-on-a-chip (OoC)

(This special issue belongs to the Section Molecular Neurobiology)

Molecularly Engineered Nanomaterials for Energy Conversion, Storage, and AI-Driven Materials Discovery

edited by

Atanu Jana

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1198 | Submission Open

Keywords: molecular engineering; energy conversion and storage; hydrogen evolution reaction (HER); oxygen evolution reaction (OER); batteries and supercapacitors; optical properties; light-emitting diodes; AI-assisted materials design

(This special issue belongs to the Section Molecular Nanoscience)

Next-Gen Biomarkers for Cancer Immunotherapy

edited by

Evangelos Koustas

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1173 | Submission Open

Keywords: cancer biomarkers; immunotherapy; circulating tumor DNA; exosomes; tumor-specific microRNAs; sin-gle-cell sequencing; spatial transcriptomics; precision oncology

(This special issue belongs to the Section Molecular Immunology)

Anti-Inflammatory Drugs: New and Old Compounds with Novel Delivery Systems Contributing to Improve the Treatment of Inflammatory Diseases

edited by S. Gorzalczany

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1169 | Submission Open

Keywords: inflammation; new compounds; novel formulation; mechanism of action; biological drug; arthritis; inflammatory bowel disease

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnosis and Prevention of Infectious Diseases

edited by

Marília Andreza Da Silva Ferreira

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1115 | Submission Open

Keywords: host–pathogen interactions; molecular diagnostics; infectious diseases; emerging and reemerging pathogens; prevention; diagnosis; molecular epidemiology; omics; molecular surveillance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Development and Discovery for Alzheimer's Disease

edited by Martha Cecilia Rosales-Hernández

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1083 | Submission Open

Keywords: Alzheimer's disease; drug design; repurposed molecules; therapeutic targets; amyloid-β; β-secretase; acetylcholin-esterase; in silico studies; oxidative stress; chemical synthesis

(This special issue belongs to the Section Molecular Neurobiology)

New Advances in Protein Analysis in Disease

edited by

Valeria Magnelli

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1050 | Submission Open

Keywords: proteomics; protein; profile; molecular mechanism; biomarker; therapeutical agent

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticle Toxicity: Beyond Chemical Composition—the Critical Role of Physicochemical Properties

edited by

Karen Khachatryan

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1048 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; physicochemical properties; risk assessment; reactive oxygen species (ROS); protein corona; cellular uptake; regulatory science; safe-by-design

(This special issue belongs to the Section Molecular Toxicology)

Molecular Mechanisms and Therapeutic Strategies in Gastrointestinal Cancer

edited by

Pedro Luiz Serrano Usón Júnior

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1029 | Submission Open

Keywords: gastrointestinal cancers; pancreatic cancer; gastric cancer; colorectal cancer; hepatobiliary cancers; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Neuroprotective Drug Development and Therapeutic Applications

edited by Jolanta Helena Kotlińska

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1013 | Submission Open

Keywords: neuropharmacology; neuroprotective drugs; dopaminergic and glutamatergic signaling; endocannabinoid system; neurodevelopmental and stress-related disorders

(This special issue belongs to the Section Molecular Neurobiology)

Advancements in Cytopathology: Challenges and Changes

edited by Panagiota Mikou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1007 | Submission Open

Keywords: cytopathology; cancer diagnosis; cytology; early cancer detection; exfoliative cytology

(This special issue belongs to the Section Molecular Biology)

Mechanistic Insights into Next-Generation Psychobiotics

edited by

Qi Su

submission deadline 31 Jul 2026 | 1 articles | Viewed by 983 | Submission Open

Keywords: gut–brain axis; psychobiotics; next-generation psychobiotics; microbiota; probiotics; postbiotics; microbial metabolites

(This special issue belongs to the Section Molecular Microbiology)

New Insights into Antimicrobial Peptides with Anticancer Activity

edited by

Esther Imperlini

submission deadline 31 Jul 2026 | 1 articles | Viewed by 960 | Submission Open

Keywords: antimicrobial peptides; cytotoxicity; selective anticancer drugs; omics approaches; anticancer peptide action

(This special issue belongs to the Section Biochemistry)

Eukaryotic Mitogenomes: Key Insights

edited by

Yuri Kartavtsev

submission deadline 31 Jul 2026 | 1 articles | Viewed by 930 | Submission Open

Keywords: eukaria; genomics; mitogenomes; structure; phylogenetic informativeness; evolution; comparative genomics; diversity; biomarker; function; mitonuclear relations

(This special issue belongs to the Section Molecular Biology)

Post-Transcriptional Gene Regulation of mRNA and Protein Expression

edited by Greco Hernández

submission deadline 31 Jul 2026 | 1 articles | Viewed by 902 | Submission Open

Keywords: translational control; protein synthesis; mRNA biochemistry; signal transduction; mTOR pathway; post-transcriptional regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Understanding Cardiotoxicity: From Mechanisms to Therapeutic Implications

edited by

Anna A. Borowiec

submission deadline 31 Jul 2026 | 1 articles | Viewed by 891 | Submission Open

Keywords: cardiotoxicity; mechanisms of cardiotoxicity; cancer-therapy-related cardiac dysfunction; chemotherapy-related cardiotoxicity; radiotherapy-related cardiotoxicity; immunotherapy-related cardiotoxicity; cardioprotection; molecular pathways; oxidative stress; apoptosis; cardiac biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 251-300 on page 6 of 64.

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