Functional and Regulatory Cancer Genomics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 687
Special Issue Editor
Interests: cancer genomics; precision medicine; data science in genomics; next-generation sequencing; translational oncology; tumor immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Functional and regulatory genomics has become central to understanding cancer initiation, progression, and therapeutic response. This Special Issue focuses on advances that elucidate how genomic, epigenomic, and transcriptomic alterations shape cancer phenotypes and regulatory networks across tumor types. Topics of interest include gene regulation and chromatin organization, enhancer–promoter interactions, non‑coding RNAs, transcriptional and epigenetic dysregulation, and the functional consequences of somatic and germline variants. Emphasis is placed on integrative approaches such as next‑generation sequencing, single‑cell and spatial genomics, CRISPR‑based functional screens, and multi‑omics analyses that connect genomic alterations with biological function. Contributions addressing tumor heterogeneity, cancer evolution, immune interactions, and translational applications—including biomarker discovery and precision oncology—are particularly encouraged. By bringing together original research and authoritative reviews, this Special Issue aims to provide mechanistic insights into cancer genomics and highlight emerging regulatory principles with potential clinical relevance.
Dr. Apostolos Zaravinos
Guest Editor
Manuscript Submission Information
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Keywords
- cancer genomics
- functional genomics
- regulatory genomics
- epigenetics
- transcriptomics
- non‑coding RNAs
- single‑cell genomics
- multi‑omics
- tumor heterogeneity
- precision oncology
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