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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Electrochemistry and Emerging Contaminants: Molecular Insights for Innovative Solutions

edited by

Miguel A. Esteso

submission deadline 30 Aug 2025 | Viewed by 87 | Submission Open

Keywords: electrochemistry; chemical reactions; removal; environmental pollution

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Aug 2025 | Viewed by 79 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Activation of the Blood–Brain Barrier and Neurological Dysfunction: 2nd Edition

edited by

Monique F. Stins

submission deadline 30 Aug 2025 | Viewed by 78 | Submission Open

Keywords: blood– brain barrier; neuro-infectious diseases; microbes; traumatic brain injury; Alzheimer’ s disease; Parkinson’ s disease; schizophrenia; cerebral vasculature; vascular heterogeneity; white matter; gray matter; therapeutic delivery; opening the BBB; neuro vascular unit

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Natural Compound for Reversing Cancer Therapy Resistance

edited by

Tae Woo Kim

submission deadline 30 Aug 2025 | Viewed by 77 | Submission Open

Keywords: cancer; natural compound; cell death; radioresistance; chemoresistance

(This special issue belongs to the Section Molecular Pharmacology)

Advancements in the Electrochemical Detection of Biomolecules: From Sensing to Environmental Applications

edited by

Habibulla Imran

submission deadline 30 Aug 2025 | Viewed by 53 | Submission Open

Keywords: biomolecules; nanomaterials; biorecognition; biomolecular detection; electrochemical

(This special issue belongs to the Section Molecular Biophysics)

State-of-the-Art Molecular Neurobiology in Chile, 2nd Edition

edited by

Juan Orellana

submission deadline 31 Aug 2025 | 4 articles | Viewed by 8178 | Submission Open

Keywords: neurological disorders; neurodegeneration; pharmacology; protein structure; neuroinflammation; neurophysiology

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Cellular Mechanisms of Spinal Cord Injury and Repair

edited by Victoria Moreno-Manzano

submission deadline 31 Aug 2025 | 7 articles | Viewed by 7506 | Submission Open

Keywords: spinal cord injury; molecular changes; neuronal degeneration; circuit regeneration; transcriptomics; cell imaging; single-cell analysis; cell communication; behavior; functional outputs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Teleost in Biomedical Research

edited by

Antonino Germanà

and

Marialuisa Aragona

submission deadline 31 Aug 2025 | 2 articles | Viewed by 7034 | Submission Open

Keywords: fish; teleost; experimental model; translational research; biomedicine; comparative studies

(This special issue belongs to the Section Molecular Biology)

Effect of Diet on Human Neurocognitive Function

edited by

Radosław Zajdel

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5374 | Submission Open

Keywords: cognition; cognitive impairment; dietary pattern; nutrients; nervous cells

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Inflammatory Bowel Disease: From Genetics to Treatment

edited by Dalin Li

submission deadline 31 Aug 2025 | 3 articles | Viewed by 5008 | Submission Open

Keywords: genetic predisposition; inflammatory bowel disease; genome-wide association study Crohn's disease; ulcerative colitis; bowel disease

(This special issue belongs to the Section Molecular Genetics and Genomics)

Therapeutic Targets and Approaches to Manage Inflammation: Disappointing Past, Current Efforts and Faint Hopes

edited by Natasha Irrera

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4653 | Submission Open

Keywords: inflammation; inflammatory pathways; resolution of inflammation; inflammasome; molecular pathways; anti-inflammatory response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mast Cell Disorders: From Molecular Mechanisms to Therapeutic Approaches

edited by Ehud Razin and

Sagi Tshori

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3193 | Submission Open

Keywords: mastocytosis; mast cell activation syndrome; mast cell disorders; theurapeutic approaches; molecular mechanisms; tumor neovascularization; inflammatory diseases; asthma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Alzheimer’s Disease

edited by Sudip Dhakal

submission deadline 31 Aug 2025 | 6 articles | Viewed by 3000 | Submission Open

Keywords: Alzheimer’ s disease; amyloid beta; tauopathy; autophagy; stress response; mitochondrial dysfunction; cognitive decline; biomarkers; disease models

(This special issue belongs to the Section Molecular Neurobiology)

Bio-Nano Interactions—3rd Edition

edited by

Massimiliano Magro

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2660 | Submission Open

Keywords: nanoparticles; proteins; smart nanomaterial surfaces; selective protein binding; nanomaterials; abiotic material; biological systems; bio-inspired inorganic materials and DNA nanotechnologies

(This special issue belongs to the Section Molecular Nanoscience)

Chitosan Materials: Recent Advances in Modification, Properties and Application

edited by

Gabriela Dudek

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2624 | Submission Open

Keywords: chitosan materials; biomedical applications; agriculture and food industry; water treatment and environmental applications; nanotechnology and advanced materials

(This special issue belongs to the Section Macromolecules)

Viruses as Therapeutic Tools: Medical and Biotechnological Applications

edited by

Víctor Romanowski

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2329 | Submission Open

Keywords: molecular virology; virus– host interactions; immunology; gene therapy vectors; vaccines; antivirals

(This special issue belongs to the Section Molecular Microbiology)

Identification of Novel Biomarkers Towards Improved Diagnosis and Management of Peripheral Vascular Diseases

edited by

Daniel P. Zalewski

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2166 | Submission Open

Keywords: vascular pathophysiology; peripheral atherosclerosis; aneurysm; venous disorders; congenital vascular malformations; molecular biomarkers; diagnostic biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Study of Neurodevelopmental and Neurological Disorders

edited by

Kazuhito Toyooka

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2005 | Submission Open

Keywords: autism spectrum disorder; ADHD; schizophrenia; intellectual disability; Alzheimer’ s disease; Parkinson’ s disorder; traumatic brain injury; epilepsy; neurodevelopmental disorders; neurological diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antioxidants: The Molecular Guardians Against Oxidative Stress

edited by

Karolina A. Wojtunik-Kulesza

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1549 | Submission Open

Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites

(This special issue belongs to the Section Biochemistry)

Insights into Novel Food Packaging Materials: Properties, Molecular Mechanisms, and Advanced Applications

edited by

Di Wang

and

Qingjun Kong

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1543 | Submission Open

Keywords: food packaging; food materials; nano materials; degradable materials; edible materials; coating; shelf life; food preservation; postharvest control

(This special issue belongs to the Section Materials Science)

Molecular Aspects of Reproductive Medicine

edited by Wei Chen

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1454 | Submission Open

Keywords: spermatogenesis; oogenesis; microenvironment; organ interactions; molecular regulation; gametogenesis; signaling pathways; reproductive disorders

(This special issue belongs to the Section Molecular Biology)

Role of MicroRNAs in Human Diseases: 2nd Edition

edited by

Lorenzo F. Sempere

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1261 | Submission Open

Keywords: microRNAs; miRNAs; miRs; preclinical models; target interaction; regulatory networks; oncology; cancer biology; cardiovascular disease; neurodegenerative conditions; diagnostic applications; therapeutic development and clinical trials

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Diagnosis and Treatment of Colorectal Cancer

edited by Steven T. Brower and Robert Pergolizzi

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1255 | Submission Open

Keywords: colorectal cancer; biomarkers; epigenetics; targeted therapy; chemoresistance; personalized cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Polymeric Biomaterials

edited by

Diego Acevedo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1207 | Submission Open

Keywords: biopolymers; biocomposites; nanomaterials; applications

(This special issue belongs to the Section Materials Science)

Biological and Molecular Aspects of Exercise Adaptation

edited by

Alessandra Modesti

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1171 | Submission Open

Keywords: exercise; redox homeostasis; metabolic state; biological; physiological

(This special issue belongs to the Section Molecular Biology)

Amyotrophic Lateral Sclerosis: From Molecular Basis to Therapies

edited by

Matteo Bordoni

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1167 | Submission Open

Keywords: ALS; pathomechanisms; genetics; epigenetics; disease models; neuroinflammation; mithocondria; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Heart Failure: From Bench to Bedside

edited by

Nadia Aspromonte

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1059 | Submission Open

Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Asthma and Allergy

edited by

Sylwia Smolińska

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1046 | Submission Open

Keywords: asthma; allergy; molecular mechanisms; exposome; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Natural Compounds in Neuroscience and Neurodegenerative Disease Therapeutics

edited by

Sarmistha Mitra

submission deadline 31 Aug 2025 | Viewed by 1020 | Submission Open

Keywords: natural products; bioactive metabolites; secondary metabolites; neuronal development; neurotrophins; neuromedicine; neurodegeneration; memory disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Microbial Genomics in the Omics Era

edited by

Surajit De Mandal

submission deadline 31 Aug 2025 | 1 articles | Viewed by 964 | Submission Open

Keywords: microbe; bioinformatics; DNA; RNA; protein; sequencing; structure; omics

(This special issue belongs to the Section Molecular Microbiology)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 869 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

New Insights into the Molecular Pathogenesis of Myeloproliferative Neoplasms

edited by

Laura Georgiana Necula

submission deadline 31 Aug 2025 | 2 articles | Viewed by 841 | Submission Open

Keywords: myeloproliferative neoplasms; molecular diagnostic; targeted therapy; biomarkers; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Metabolic Engineering and Synthetic Biology of Yeasts

edited by

Justyna Ruchała

submission deadline 31 Aug 2025 | 1 articles | Viewed by 815 | Submission Open

Keywords: yeast metabolic engineering; synthetic biology; CRISPR-Cas9; metabolic pathways; bio-based chemicals; bioprocess engineering; yeast strain optimization; industrial biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Physiological and Pathological Hypoxia: The Battle between the Protective and Deleterious Effects of Oxygen Deprivation

edited by

Michele Samaja

Michele Maffia

Rita Paroni

and Giacomo Strapazzon

submission deadline 31 Aug 2025 | 1 articles | Viewed by 811 | Submission Open

Keywords: physiological hypoxia; pathological hypoxia; hypoxia; signalling pathway; inflammation; oxygen transport

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Therapeutic Horizons of Oligosaccharides: Molecular Mechanisms and Therapeutic Potential

edited by

Abdelali Daddaoua

and

María Núñez-Núñez

submission deadline 31 Aug 2025 | 1 articles | Viewed by 796 | Submission Open

Keywords: oligosaccharides; bacterial infection; multidrug-resistant

(This special issue belongs to the Section Molecular Microbiology)

Genes and Human Diseases: 3rd Edition

edited by

Mikhail I. Churnosov

submission deadline 31 Aug 2025 | 2 articles | Viewed by 794 | Submission Open

Keywords: genes; human diseases; genetic-epidemiological studies; genetic factors; susceptibility

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Photobiomodulation Therapy

edited by Maria Fernanda Setúbal Destro Rodrigues

submission deadline 31 Aug 2025 | 2 articles | Viewed by 728 | Submission Open

Keywords: photobiomodulation; dosimetric parameters; human diseases; modulation of inflammation; photobiomodulation therapy; molecular mechanisms; preclinical and clinical studies; therapeutic applications of PBM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Structural and Functional Properties of G-Quadruplexes and Aptamers

edited by

Antonella Virgilio

Veronica Esposito

and

Aldo Galeone

submission deadline 31 Aug 2025 | 1 articles | Viewed by 709 | Submission Open

Keywords: G-quadruplex structure; aptamer; DNAzyme; catalytic G-quadruplexes

(This special issue belongs to the Section Molecular Biology)

Glycoconjugates: From Structure to Therapeutic Application

edited by Rosana Ribić

submission deadline 31 Aug 2025 | 1 articles | Viewed by 666 | Submission Open

Keywords: glycoconjugates (glycoproteins and glycopeptides; glycolipids; proteoglycans); glyconanoparticles; carbohydrate-based therapeutics; glycomics; glycosylation; glycoengineering; glycobiology; synthesis of glycoconjugates; vaccine development; drug delivery; biomarkers; diagnostics; immunotherapy; regenerative medicine; therapeutic applications

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition

edited by

Hui Qiao

and Hongtuo Fu

submission deadline 31 Aug 2025 | 1 articles | Viewed by 657 | Submission Open

Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture

(This special issue belongs to the Section Molecular Biology)

Environmental Influences on Cellular Responses

edited by

Marcus Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 631 | Submission Open

Keywords: cell/environment interaction; cell signaling; mechanobiology; photobiology; thermobiology; enviromics; cell-cell communication; cell-cell interaction

(This special issue belongs to the Section Molecular Biology)

Advanced Research on Cancer Stem Cells

edited by

Ilze Štrumfa

submission deadline 31 Aug 2025 | 1 articles | Viewed by 582 | Submission Open

Keywords: cancer stem cells; tumour microenvironment; pancreatic cancer; glioblastoma; gastric cancer; breast cancer; lung cancer; colorectal cancer; renal cancer; liver cancer; melanoma; leukemia; lymphoma

(This special issue belongs to the Section Molecular Oncology)

Vitamin K in Disease Mechanisms and Therapy

edited by Maria Kokozidou

submission deadline 31 Aug 2025 | Viewed by 568 | Submission Open

Keywords: vitamins K; vitamins K-soluble proteins; vitamin K-dependent clotting factors; matrix Gla protein; calcification of blood vessels; vascular stiffness; cardiac output; stroke volume

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Products from Plants: Association with Human Health and Therapeutic Benefits

edited by

Andrey Marchev

and

Nikolina Mihaylova

submission deadline 31 Aug 2025 | 1 articles | Viewed by 555 | Submission Open

Keywords: botanical products; phytochemicals; bio/pharmacological compounds; cellular and molecular targets; molecular and physiological mechanism; human health; disease prevention and treatment; inflammatory diseases; age-related disorders; chronic and (auto)immune diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 31 Aug 2025 | 1 articles | Viewed by 549 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms Underlying the Pathogenesis of Genetic Diseases

edited by

Debora Baroni

submission deadline 31 Aug 2025 | 1 articles | Viewed by 530 | Submission Open

Keywords: genetic diseases; genotype– phenotype correlations; multi-omics approaches; current and investigational therapeutical approaches; personalized medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Focus on the Tryptophan Pathway

edited by

Burkhard Poeggeler

submission deadline 31 Aug 2025 | 1 articles | Viewed by 500 | Submission Open

Keywords: aging; indole-3-propionic acid; kynurenic acid; melatonin; serotonin; tryptophan

(This special issue belongs to the Section Molecular Biology)

Cutting Edge Advances in Antitumor Properties of Natural Products

edited by

Francesca Giordano

and

Maria Luisa Panno

submission deadline 31 Aug 2025 | Viewed by 471 | Submission Open

Keywords: natural product; cancer; cell signaling; cell death and differentiation; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nanoparticles in Molecular Pharmaceutics

edited by

Qingxin Mu

submission deadline 31 Aug 2025 | Viewed by 322 | Submission Open

Keywords: nanoparticles; molecular pharmaceutics; drug delivery; nanomedicine; nanoformulation

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms and Targeted Therapy of Lymphedema and Lipedema

edited by

Raghu P. Kataru

and Geoffrey E. Hespe

submission deadline 31 Aug 2025 | Viewed by 281 | Submission Open

Keywords: secondary lymphedema; breast cancer related lymphedema; chronic CD4+ T cell inflammtion Th2 driven fribrosis; lymphatic pathophysiology; tissue fibrosis; lymphovenous bypass; lymph node transplanatation; targeted therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 451-500 on page 10 of 69.

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