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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanism of Immune Response

edited by Marisa Mariel Fernández

submission deadline 20 Sep 2026 | Viewed by 327 | Submission Open

Keywords: training of the innate immune response; antigen recognition; cell migration; autoimmune processes; cell differentiation; tolerance; molecular responses of epithelial cells to foreign stimuli; alterations in immune checkpoints; modulation of immune responses; mechanisms of hypersensitivity

(This special issue belongs to the Section Molecular Immunology)

Environmental and Human Adverse Effects of Micro and Nanoplastics: 2nd Edition

edited by

Elena Niccolai

submission deadline 20 Sep 2026 | Viewed by 317 | Submission Open

Keywords: micro and nanoplastics; environmental pollution; micro and nanoplastic toxicity; human health

(This special issue belongs to the Section Molecular Toxicology)

Mitochondrial Dysfunction in Disease: Mechanisms, Biomarkers and Emerging Therapies

edited by

Alexandre Umpierrez Amaral

submission deadline 20 Sep 2026 | Viewed by 305 | Submission Open

Keywords: mitochondria; bioenergetic homeostasis; calcium homeostasis; redox homeostasis; oxidative stress; biogenesis; mitophagy; dynamics

(This special issue belongs to the Section Biochemistry)

Advanced Composite Materials: Molecular Design and Applications

edited by Fan Yang

submission deadline 20 Sep 2026 | Viewed by 253 | Submission Open

Keywords: multifunctional applications; mechanical and physical properties; extreme environments; molecular dynamics analysis; composite molecular design; preparation; simulation; and characterization

(This special issue belongs to the Section Materials Science)

Kidney Diseases: Molecular Research and Novel Therapies

edited by Niels Olsen Saraiva Camara

submission deadline 20 Sep 2026 | Viewed by 236 | Submission Open

Keywords: kidney disease; immunology and inflammation; zebrafish models; therapeutic targets; modern-era drivers of renal pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis and Molecular Applications of Nanomaterials

edited by

Fernando J. Pereira

A. Javier Aller

and

Roberto Lopez

submission deadline 20 Sep 2026 | Viewed by 201 | Submission Open

Keywords: nanomaterials; synthesis; molecular applications

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Advances in Retinal Degeneration

edited by Sayan Ghosh

submission deadline 20 Sep 2026 | Viewed by 179 | Submission Open

Keywords: retinal degeneration; photoreceptors; retinal pigmented epithellium (RPE) cells; retinal ganglion cells; glial cells; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Structure and Functions of Ribosomal Proteins

edited by

Youri Timsit

submission deadline 20 Sep 2026 | Viewed by 162 | Submission Open

Keywords: protein synthesis; translation; translocation; dynamics; folding; network; assembly; evolution

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Serotonin

edited by Joachim Neumann

submission deadline 20 Sep 2026 | Viewed by 153 | Submission Open

Keywords: serotonin; serotonin receptors; migraine; depression; hypertension; heart failure; arrhythmias

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 3rd Edition

edited by

Vicenç Ruiz de Porras

submission deadline 20 Sep 2026 | Viewed by 146 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cell carcinoma; upper urinary tract tumors; testicular cancer; predictive and prognostic biomarkers; tumor progression; novel treatment strategies; chemotherapy; immunotherapy; target therapies; drug resistance mechanisms; tumor microenvironment; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Pharmacognosy: Bioactive Natural Products and Mechanistic Insights

edited by Luísa Mota Da Silva

submission deadline 20 Sep 2026 | Viewed by 126 | Submission Open

Keywords: pharmacognosy; natural products; bioactive compounds; phytochemistry; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

Exopolysaccharides of Microbial Origin: Production, Analysis and Modification

edited by Marzena Jedrzejczak-Krzepkowska and

Karolina Ludwicka

submission deadline 20 Sep 2026 | Viewed by 122 | Submission Open

Keywords: exopolysaccharide; biopolymer; biofilm; microorganism; biosynthesis; genetic engineering; molecular design; modification; analysis

(This special issue belongs to the Section Molecular Microbiology)

Identification and Analysis of Interspecies Interactions in Microbial Biofilms

edited by

Terence L. Marsh

submission deadline 20 Sep 2026 | Viewed by 112 | Submission Open

Keywords: biofilm; interspecies communication; biofilm demographics; competition; commensalism; parasitism; mutualism; methodologies

(This special issue belongs to the Section Molecular Microbiology)

RNA Structure and Regulation in Biological Processes

edited by Changrui Lu

submission deadline 20 Sep 2026 | Viewed by 13 | Submission Open

Keywords: RNA structure; RNA three-dimensional conformation; RNA dynamics; RNA chemical modifications; structural biology; RNA– protein interactions; RNA structures in plant disease resistance; viral RNA structure and function; computational structure prediction; host– pathogen interactions

(This special issue belongs to the Section Biochemistry)

Molecular Insight Into Mesothelioma

edited by

Fabrizio Celesti

submission deadline 25 Sep 2026 | Viewed by 25 | Submission Open

Keywords: mesothelioma; molecular subtypes; molecular landscape; tumor microenvironment; epigenetics; multiomics; therapeutic strategies; immunotherapy; biomarkers; molecular stratification

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Tea Flavor and Chemistry

edited by

Wei Xu

submission deadline 29 Sep 2026 | Viewed by 132 | Submission Open

Keywords: tea processing; tea chemistry; tea functional components; tea sensory evaluation; tea quality control

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms in Forensic Pathology

edited by

Vittorio Fineschi

submission deadline 29 Sep 2026 | Viewed by 79 | Submission Open

Keywords: molecular investigation; molecular thanatocronology; molecular autopsy; lesion vitality; molecu-lar forensic toxicology; pharmacogenomics; molecular identification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant Transporters and Tolerance Proteins

edited by Kun Qiao

submission deadline 29 Sep 2026 | Viewed by 37 | Submission Open

Keywords: heavy metal; transporter; antioxidant; ornamental plants and horticulture; ion transport; phytoremediation; biofortification

(This special issue belongs to the Section Molecular Plant Sciences)

Common Mechanisms in Gestational Diabetes, Preeclampsia, and Coronavirus Disease 2019

edited by

Sandor G. Vari

submission deadline 30 Sep 2026 | 7 articles | Viewed by 11587 | Submission Open

Keywords: gestational diabetes; preeclampsia; inflammation; immunoglobulins; glycolisation; platelet aggregation; microvascular thrombosis; coronavirus disease 2019

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)

edited by

Rima Dardik

and

Tami Livnat

submission deadline 30 Sep 2026 | 1 articles | Viewed by 958 | Submission Open

Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism, Pathogenesis, and Precision Therapeutics in Thyroid Cancer

edited by

Laura Sterian Ward

submission deadline 30 Sep 2026 | Viewed by 629 | Submission Open

Keywords: thyroid cancer; molecular pathogenesis; driver mutations; tumor microenvironment; targeted therapy; resistance mechanisms; immunotherapy; precision oncology; liquid biopsy; prognostic biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dynamics of Fascia: Cellular, Molecular, and Biochemical Mechanisms

edited by

Caterina Fede

submission deadline 30 Sep 2026 | 1 articles | Viewed by 307 | Submission Open

Keywords: fascia; homeostasis and pathology; extracellular matrix remodeling; fibroblast signaling; chronic pain; fibrosis and inflammation; hormonal regulation

(This special issue belongs to the Section Biochemistry)

Natural Products in Drug Discovery and Development: 2nd Edition

edited by Tian-Le Gao

submission deadline 30 Sep 2026 | 1 articles | Viewed by 225 | Submission Open

Keywords: natural product components; traditional medicine; biological entropy reduction; aromatic drugs; essential oils; gut microbiota modulation; probiotics; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

Phytochemical Insights and Green Extraction Strategies for Bioactive Natural Compounds

edited by

Ana M. L. Seca

and

Gonçalo Pereira da Rosa

submission deadline 30 Sep 2026 | Viewed by 188 | Submission Open

Keywords: plant and algal bioactive metabolites; phytochemistry; green extraction techniques; natural sustainable solvents (NADES); structural elucidation of natural molecules; molecular characterization

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 132 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Protein Dynamics in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities

edited by Slovénie Pyndiah

submission deadline 30 Sep 2026 | Viewed by 98 | Submission Open

Keywords: drug resistance; cancer proteome; protein turnover; post-translational modifications; targeted therapy; stress adaptation

(This special issue belongs to the Section Molecular Oncology)

Integrating Multi-Omics Approaches in Fish Immunology To Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 71 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Procoagulant Platelets in Vascular Disease and Beyond

edited by

Paresh P. Kulkarni

submission deadline 30 Sep 2026 | Viewed by 65 | Submission Open

Keywords: procoagulant platelets; thrombosis; hemostasis; coagulation; bleeding; vascular disease; cancer; cardiometabolic syndrome; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

CAR-T Cell Biology and Clinical Translation

edited by

Antonio Pérez Martínez

and

Daniel Ka Leung Cheuk

submission deadline 30 Sep 2026 | Viewed by 33 | Submission Open

Keywords: chimeric antigen receptor (CAR) T cells; gene engineering; genome editing; T‑cell exhaustion; tumor microenvironment; cytokine release syndrome (CRS); ICANS (immune effector cell– associated neurotoxicity syndrome); allogeneic CAR‑T cells; dual‑targeting CAR‑T cells; point‑of‑care manufacturing

(This special issue belongs to the Section Molecular Immunology)

Molecular Studies of Cartilage Deformation

edited by

Kazuo Yudoh

submission deadline 30 Sep 2026 | Viewed by 28 | Submission Open

Keywords: osteoarthritis; chondrocyte; mitochondria function; mechanical stress; oxidative stress; cartilage metabolism

(This special issue belongs to the Section Molecular Biology)

Enhancing Plant Traits Through In Vitro Culture

edited by Jacek Gawroński

submission deadline 30 Sep 2026 | Viewed by 22 | Submission Open

Keywords: plant tissue culture; somatic embryogenesis; organogenesis; micropropagation; callus culture; in vitro regeneration; in vitro mutagenesis; haploid and doubled haploid production; molecular markers; genetic analysis; genomics; transcriptomics; epigenetic regulation; proteomic profiling; molecular mechanisms; gene expression analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Ion and Molecular Transport in Nanopores/Channels

edited by Haiqi Gao

submission deadline 30 Sep 2026 | Viewed by 14 | Submission Open

Keywords: gas separation; desalination; ion separation; COF; nanoporous graphene; first-principle calculation; molecular dynamics simulation; machine learning

(This special issue belongs to the Section Materials Science)

Molecular Research into the Applications of Metabolites from Marine Organisms

edited by Carlos García

submission deadline 30 Sep 2026 | Viewed by 9 | Submission Open

Keywords: quantitative analysis; secondary metabolites; bioactive; disease; molecular insight; natural compounds

(This special issue belongs to the Section Biochemistry)

Nutritional Approaches to Cardiovascular Health

edited by Aleksandar Kibel

submission deadline 30 Sep 2026 | Viewed by 6 | Submission Open

Keywords: cardiovascular disease; dietary patterns; hypertension; dyslipidemia; inflammation; endothelial function; omega-3 fatty acids; dietary fiber; gut microbiome; precision nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Oxidative Stress Responses in Cardiovascular Diseases

edited by Vladimir Jakovljevic

submission deadline 20 Oct 2026 | 1 articles | Viewed by 5892 | Submission Open

Keywords: antioxidant capacity; cardiovascular disease; cell death; endothelial dysfunction; ischemia/reperfusion injury; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Plant–Microbe Interaction

edited by

Raja Ben-Laouane

and

Mohamed Ait-El-Mokhtar

submission deadline 20 Oct 2026 | 1 articles | Viewed by 2685 | Submission Open

Keywords: biomarkers; molecular biotechnology; cell signalling; microbiota signaling; genetic editing of microbes; plant-microbe stress response; plant-microbe stress mitigation; plant-microbe underlying mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Circumventing Resistance to Channel-Targeting Insecticides: A Challenge for Global Health and Food Security

edited by

Bruno Lapied

and David Barry Sattelle

submission deadline 20 Oct 2026 | 1 articles | Viewed by 848 | Submission Open

Keywords: pest insects and resistance; resistance in insect vectors of human and livestock diseases; mechanisms of resistance; circumventing resistance; ion channels and resistance; integrated approaches to resistance management; alternating insecticide classes; minimizing risk to beneficial insects; novel control strategies

(This special issue belongs to the Section Molecular Biology)

Exploring Molecular Insights in Oral Health and Disease

edited by

Iulia-Ioana Stanescu-Spinu

and

Tudor Claudiu Spînu

submission deadline 20 Oct 2026 | Viewed by 304 | Submission Open

Keywords: oral health; saliva; oral diseases; molecular insights; molecular targets; oral cavity physiology; wound healing; oral microbiome; oral biocompatibility; material interactions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pharmacological Approaches in Inflammation, Aging, and Cardiovascular Diseases

edited by

Omer Dzemali

and

Era Gorica

submission deadline 20 Oct 2026 | Viewed by 130 | Submission Open

Keywords: inflammation; aging; cardiovascular diseases; approaches; translational research; therapeutic targets

(This special issue belongs to the Section Molecular Pharmacology)

Advance in Plant Abiotic Stress: 4th Edition

edited by

De-Guo Han

and

Xingguo Li

submission deadline 30 Oct 2026 | 1 articles | Viewed by 732 | Submission Open

Keywords: abiotic stress; cold; drought; salt; heat; nutrient deficiency; secondary metabolism; stress resistance; plant

(This special issue belongs to the Section Molecular Plant Sciences)

Precision Photosynthesis: Mechanisms and Applications in Controlled Environments

edited by

Jiangtao Hu

submission deadline 30 Oct 2026 | Viewed by 88 | Submission Open

Keywords: controlled environment agriculture (CEA); photobioreactor; plant growth chamber; light-emitting diode (LED) spectrum; photosynthetic efficiency; acclimation; synthetic biology; metabolic engineering; high-throughput phenotyping; predictive modeling; vertical farming

(This special issue belongs to the Section Molecular Plant Sciences)

Nanostructured Materials and Functional Molecules for Sustainable Applications

edited by

Giulia Rando

Maria Rosaria Plutino

and

Silvia Sfameni

submission deadline 30 Oct 2026 | Viewed by 74 | Submission Open

Keywords: nanostructured materials; functional molecules; molecular design; sustainable materials; carbon nanotubes (CNTs); biochar; nanocomposites; nanohybrids; surface functionalization; molecular interactions; green synthesis; advanced functional materials

(This special issue belongs to the Section Materials Science)

The Mechanisms of Cucurbit Breeding, Cultivation and Quality Regulation

edited by Xiaotao Ding and Yongxue Zhang

submission deadline 30 Oct 2026 | Viewed by 57 | Submission Open

Keywords: omics; cultivation; breeding; quality; abiotic stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism in Pulmonary Embolism

edited by

Hugo Hyung Bok Yoo

submission deadline 30 Oct 2026 | Viewed by 27 | Submission Open

Keywords: pulmonary embolism; thrombosis; molecular mechanisms; coagulation; endothelial dysfunction; biomarkers; inflammation; fibrinolysis; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cell Biology of Viruses

edited by

Shanhui Ren

submission deadline 30 Oct 2026 | Viewed by 18 | Submission Open

Keywords: molecular virology; cellular virology; virus– host interface; intracellular trafficking; cellular pathogenesis

(This special issue belongs to the Section Molecular Microbiology)

Design of Bioactive Agents and Interaction with Biological Systems

edited by

Josef Jampilek

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4247 | Submission Open

Keywords: natural and synthetic compounds; bioactive agents and materials; design and discovery; targeting; intermolecular interactions; omics; structure and dynamics of biomolecules; theoretical analysis of biomolecular structures; analytical and biophysical methods; molecular biology/biochemistry; chemical biology/biological chemistry

(This special issue belongs to the Section Molecular Biology)

Novel Mechanisms of Receptor Activation

edited by

Zong Jie Cui

submission deadline 31 Oct 2026 | 1 articles | Viewed by 801 | Submission Open

Keywords: G protein-coupled receptors; nuclear (steroid) hormone receptors; catalytic receptors; receptor structural motifs important for activation; receptor pharmacophores; structure– function correlates; cellular functions; integrated physiology; compartmentalized GPCRs; receptor pharmacology; aryl hydrocarbon receptor (AHR); “ orphan” GPCRs

(This special issue belongs to the Section Biochemistry)

Cotton Breeding and Genetics: Advances and Perspectives

edited by Xuwu Sun

submission deadline 31 Oct 2026 | Viewed by 71 | Submission Open

Keywords: molecular design breeding; smart breeding; CRISPR-Cas; artificial intelligence; cotton genomics; multi-omics; high-throughput phenotyping; trait prediction; genome editing; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Organ Axis: Insights from Molecular Metabolism

edited by

Peiwen Wang

submission deadline 31 Oct 2026 | Viewed by 70 | Submission Open

Keywords: organ axis; molecular metabolism; interorgan crosstalk; metabolic regulation; metabolic diseases; biomarkers; molecular pathways; metabolites

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Male Reproductive and Sexual Health

edited by

Aris Kaltsas

submission deadline 31 Oct 2026 | Viewed by 11 | Submission Open

Keywords: male reproductive health; male sexual health; male infertility; erectile dysfunction (ED); prostate inflammation; Peyronie's disease; biomarkers; molecular mechanisms; androgen deprivation; nanotechnology

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Displaying special issue 3251-3300 on page 66 of 67.

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