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New Advances in Plant–Microbe Interaction

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: 30 August 2025 | Viewed by 663

Special Issue Editors


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Guest Editor
Laboratory of Environment and Health, Department of Biology, Faculty of Sciences & Techniques, Moulay Ismail University, Errachidia 52000, Morocco
Interests: biotic and abiotic stresses; plant stress response; biofertilizers/biostimulants; PGPR; rhizobia; compost; AMF; salinity; drought; biochar
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E-Mail Website
Guest Editor
Department of Biology, Hassan II University of Casablanca, Casablanca 20000, Morocco
Interests: plant tolerance; biotic and abiotic stresses; biostimu-lants/biofertilizers; salinity, drought; AMF; PGPR; organic amendments
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent advances in molecular biology have considerably improved our understanding of the interactions between plants and microbes. Studies on plant microbiota reveal that complex molecular signals regulate these interactions, promoting growth and resistance to abiotic and biotic stresses. In addition, mechanisms such as signalling by bacterial and fungal effectors, and the regulation of plant defence pathways via interfering RNA, are increasingly well understood. Omics approaches are making it possible to identify the key genes involved in these interactions. These advances pave the way for applications in sustainable agriculture, notably through the use of biofertilisers and biopesticides based on optimised symbioses. This special issue of IJMS will feature original research and review articles with the aim of providing an overview of advances in the molecular basis of interactions between plants and microbes. We particularly welcome research and review articles that contribute to (but are not limited to) the following topics:

  • Molecular recognition and signalling of the microbiota
  • Regulation of plant gene expression in response to microbes
  • Microbial modulation of plant immunity
  • Molecular mechanisms of plant-microbe communication 
  • Omics approaches to the study of plant-microbe interactions 
  • Molecular interaction plants-microbes for tolerance to a/biotic stresses
  • Molecular biotechnology for improving stress resistance

Dr. Raja Ben-Laouane
Dr. Mohamed Ait-El-Mokhtar
Guest Editors

Manuscript Submission Information

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Keywords

  • biomarkers
  • molecular biotechnology
  • cell signalling
  • microbiota signaling
  • genetic editing of microbes
  • plant-microbe stress response
  • plant-microbe stress mitigation
  • plant-microbe underlying mechanisms

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Published Papers (1 paper)

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Research

21 pages, 4413 KiB  
Article
Integrated Transcriptomic and Metabolomic Analysis Reveals the Regulation Network of CEBiP in Rice Defense Against Magnaporthe oryzae
by Qi Zheng, Jiandong Bao, Lin Li, Zifang Shen, Jiaoyu Wang, Asen Daskalov, Xueming Zhu and Fucheng Lin
Int. J. Mol. Sci. 2025, 26(11), 5194; https://doi.org/10.3390/ijms26115194 - 28 May 2025
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Abstract
Rice blast disease is a major threat to rice yields. Sustainable control relies on resistant varieties, where plant immunity is triggered by pattern recognition receptors like receptor-like proteins (RLPs). The rice RLP chitin-elicitor binding protin (CEBiP) recognizes fungal chitin and confers blast resistance [...] Read more.
Rice blast disease is a major threat to rice yields. Sustainable control relies on resistant varieties, where plant immunity is triggered by pattern recognition receptors like receptor-like proteins (RLPs). The rice RLP chitin-elicitor binding protin (CEBiP) recognizes fungal chitin and confers blast resistance to pathogen Magnaporthe oryzae. However, understanding of the broader signaling and metabolomic pathways associated with CEBiP activation remains limited. Here, we performed an integrated transcriptomic and metabolomic analysis of the rice Zhonghua 11 genotype and CEBiP knockout plants. Both plants were infected with M. oryzae, and infected leaves were harvested at 24, 48, and 72 hpi for RNA sequencing and Liquid Chromatography-Tandem Mass Spectrometry analysis. Transcriptomics identified a total of 655 genes that were differentially regulated upon knockout of CEBiP; they were mainly related to diterpenoid/phenylpropanoid biosynthesis, nitrogen metabolism, the mitogen-activated protein kinasesignaling pathway, plant–pathogen interaction, and plant hormone signal transduction. The presence of a large number of pathogenesis-related protein 1 family genes indicates the key role of salicylic acid (SA) in CEBiP immunity. Metabolomics detected a total of 962 differentially accumulated metabolites and highlights the roles of caffeine and glutathione metabolism in CEBiP-mediated immunity. Since caffeine and glutathione metabolism can regulate SA signaling, we propose that SA signaling plays a central role in the CEBiP immune function. Full article
(This article belongs to the Special Issue New Advances in Plant–Microbe Interaction)
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