Novel Biomaterials for Regenerative Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 82642
Special Issue Editor
Interests: reprogramming; differentiation; Brain Blood Barrier (BBB); iPSC; drug discovery; disease in a dish model
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Novel biomaterials are in the heart of regenerative medicine. The main goals for generating in vitro models for in vivo applications, include generating organs for transplantation and organ models for drug discovery. The focus is to generate organoids that will faithfully represent human organs. The composition of the biomaterials, their originality and suitability to each organ is very important for the functionality of the organoid/organ. In the area of drug discovery, iPSC-derived BBB organoid models, for example, will fasten the process of drug discovery by early selecting the drugs according to their BBB penetrance. The success in formation heart organoid that will represent the complexity of heart tissue, is dependent, for example, on the biomaterials used including peptides cross-linked to the scaffolds. Success in future heart scar replacement will involve those biomaterial that will create environment that promote tissue regeneration and will not activate the immune response and lead to graft rejection.
Dr. Rivka Ofir
Collection Editor
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Keywords
- biomaterials
- organoid
- scaffold
- in vitro drug discovery
- tissue engineering
- cell transplantation
- immune modulation
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