Next Article in Journal
Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine
Next Article in Special Issue
Mesenchymal Stem-Cell Remodeling of Adsorbed Type-I Collagen—The Effect of Collagen Oxidation
Previous Article in Journal
Salicylic Acid Enhances Adventitious Root and Aerenchyma Formation in Wheat under Waterlogged Conditions
Previous Article in Special Issue
Adipose Tissue Uses in Peripheral Nerve Surgery
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 23
Issue 3
10.3390/ijms23031244
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

The Role of Biomaterials in Peripheral Nerve and Spinal Cord Injury: A Review

by
Ben Kaplan
1,2 and
Shulamit Levenberg
1,*
1
Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa 3200003, Israel
2
Bruce Rapaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525433, Israel
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(3), 1244; https://doi.org/10.3390/ijms23031244
Submission received: 31 December 2021 / Revised: 19 January 2022 / Accepted: 20 January 2022 / Published: 23 January 2022
(This article belongs to the Special Issue Novel Biomaterials for Regenerative Medicine)
Browse Figures
Versions Notes

Abstract

Peripheral nerve and spinal cord injuries are potentially devastating traumatic conditions with major consequences for patients’ lives. Severe cases of these conditions are currently incurable. In both the peripheral nerves and the spinal cord, disruption and degeneration of axons is the main cause of neurological deficits. Biomaterials offer experimental solutions to improve these conditions. They can be engineered as scaffolds that mimic the nerve tissue extracellular matrix and, upon implantation, encourage axonal regeneration. Furthermore, biomaterial scaffolds can be designed to deliver therapeutic agents to the lesion site. This article presents the principles and recent advances in the use of biomaterials for axonal regeneration and nervous system repair.
Keywords: spinal cord injury; peripheral nerve injury; biomaterials spinal cord injury; peripheral nerve injury; biomaterials

Share and Cite

MDPI and ACS Style

Kaplan, B.; Levenberg, S. The Role of Biomaterials in Peripheral Nerve and Spinal Cord Injury: A Review. Int. J. Mol. Sci. 2022, 23, 1244. https://doi.org/10.3390/ijms23031244

AMA Style

Kaplan B, Levenberg S. The Role of Biomaterials in Peripheral Nerve and Spinal Cord Injury: A Review. International Journal of Molecular Sciences. 2022; 23(3):1244. https://doi.org/10.3390/ijms23031244

Chicago/Turabian Style

Kaplan, Ben, and Shulamit Levenberg. 2022. "The Role of Biomaterials in Peripheral Nerve and Spinal Cord Injury: A Review" International Journal of Molecular Sciences 23, no. 3: 1244. https://doi.org/10.3390/ijms23031244

APA Style

Kaplan, B., & Levenberg, S. (2022). The Role of Biomaterials in Peripheral Nerve and Spinal Cord Injury: A Review. International Journal of Molecular Sciences, 23(3), 1244. https://doi.org/10.3390/ijms23031244

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop