Probiotic Fermentation: Advances in Research on Probiotic Properties and Fermentation Techniques

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Microbiology".

Deadline for manuscript submissions: 29 January 2026 | Viewed by 364

Special Issue Editors

Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China
Interests: probiotics; microorganisms; fermentation; food processing; intestinal flora; metabolism

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Guest Editor
Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China
Interests: probiotics; microorganisms; fermentation; food processing; gut immunology

Special Issue Information

Dear Colleagues,

Probiotic fermentation has gained significant attention due to its critical role in enhancing food functionality, promoting gut health, and contributing to sustainable food production. Recent advances in microbial genomics, fermentation technology, and bioactivity characterization have expanded our understanding of probiotic strains and their applications. This Special Issue aims to compile cutting-edge research on novel probiotic properties, innovative fermentation techniques, and their implications for food science, nutrition, and biotechnology.

We welcome the submission of original research, reviews, and methodological studies that address challenges and opportunities in probiotic applications alongside the following aims:

  • Uncover novel probiotic strains or microbial consortia with enhanced functional properties (e.g., acid tolerance, bile resistance, and prebiotic production).
  • Develop innovative fermentation strategies to optimize probiotic viability, metabolic activity, and product quality.
  • Elucidate the molecular mechanisms underlying probiotic–host interactions, gut microbiota modulation, and health benefits.
  • Address translational challenges in scaling probiotic fermentation for industrial applications, including cost-effectiveness and sustainability.

Dr. Peng Du
Prof. Dr. Aili Li
Guest Editors

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Keywords

  • probiotic fermentation
  • gut microbiota
  • postbiotics
  • fermentation technology
  • microbial viability
  • functional foods
  • synbiotics
  • industrial biotechnology
  • bioactive metabolites

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Published Papers (1 paper)

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Research

17 pages, 2387 KiB  
Article
Application of Lactobacillus helveticus KLDS 1.1105 Postbiotics for Resisting Pathogenic Bacteria Infection in the Intestine
by Peng Du, Jiaying Liu, Chengwen Hu, Jianing Zhang, Miao Li, Yu Xin, Libo Liu, Aili Li and Chun Li
Foods 2025, 14(15), 2659; https://doi.org/10.3390/foods14152659 - 29 Jul 2025
Viewed by 301
Abstract
Postbiotics, defined as metabolites produced by probiotics, encompass both bacterial cells and their metabolic byproducts, and offer significant health benefits to the host. However, there are relatively few reports on their effects on intestinal microbiota. In this study, we investigated the components, total [...] Read more.
Postbiotics, defined as metabolites produced by probiotics, encompass both bacterial cells and their metabolic byproducts, and offer significant health benefits to the host. However, there are relatively few reports on their effects on intestinal microbiota. In this study, we investigated the components, total antioxidant capacity of Lactobacillus helveticus postbiotics (LHPs) and their impact on intestinal flora using the Simulator for Human Intestinal Microecology Simulation (SHIME). The results indicate that the primary components of postbiotics include polysaccharides, proteins, and organic acids. Furthermore, LHPs have a strong ability to inhibit the growth of harmful bacteria while promoting the growth of probiotics. Additionally, LHPs significantly increased the total antioxidant capacity in the intestine and regulated the balance of intestinal microbiota. Notably, there was also a significant increase in the content of short-chain fatty acids (SCFAs) in the intestine. Overall, LHPs have the potential to aid in the prevention and treatment of diseases by enhancing gut microbiology. Full article
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