Food Polysaccharides: Molecular Structure, Bioactive Properties, and Emerging Applications

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Nutrition".

Deadline for manuscript submissions: 30 October 2026 | Viewed by 1015

Special Issue Editor


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Guest Editor
Institute of Mitochondrial Biology and Medicine, Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Sciences and Technology, Xi'an Jiaotong University, Xi'an, China
Interests: functional foods; polysaccharides; natural products; antioxidants; food chemistry; bioactive compounds

Special Issue Information

Dear Colleagues,

Food polysaccharides, as natural macromolecules, have attracted considerable interest in food science and medicine due to their unique molecular structures and biological activities. Recently, extensive research has been conducted on the molecular characteristics and mechanisms behind the biological functions of these polysaccharides. These studies have clarified the relationships between their structures and functions, offering innovative approaches for their use in emerging areas such as functional foods, drug delivery systems, and biomaterials. Although many studies have highlighted the health benefits of food polysaccharides—including immune modulation, antioxidant effects, and anti-cancer properties—there are still inconsistencies in the findings and perspectives across different research. Technological advances in materials science and nanotechnology provide new possibilities to improve the functional applications of polysaccharides.

In this context, we invite submissions for a Special Issue that focuses on the detailed structural analysis of polysaccharides; their biological mechanisms of action; the nutritional roles of polysaccharides or natural polysaccharides within food systems; and developments in polysaccharide-based nanomaterials for drug delivery and biosensing. Additionally, research that explores the link between polysaccharide structure and activity through the integration of big data and artificial intelligence is also welcome.

Prof. Dr. Yali Zhang
Guest Editor

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Keywords

  • natural polysaccharides
  • molecular structure
  • health benefits
  • bioactive properties
  • chronic diseases prevention
  • anti-aging
  • dietary regulation of oxidative stress
  • gut health
  • 3d food printing
  • delivery systems

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Published Papers (1 paper)

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Research

23 pages, 3629 KB  
Article
Characterization of Mannose-Rich Exopolysaccharides from Kefir Lactic Acid Bacteria and Their Techno-Functional Potential in Fermented Milk
by Tingting Zhang, Yunyan Li, Jingjing Leng, Zi Ye, Zhufang Duan, Bingfang Huang, Chunqiu Zhang, Muhammad Imran, Muhammad Azam, Bohan Sun and Yanglei Yi
Foods 2026, 15(8), 1322; https://doi.org/10.3390/foods15081322 - 10 Apr 2026
Viewed by 672
Abstract
Kefir grains are a valuable source of exopolysaccharide (EPS)-producing lactic acid bacteria (LAB) with potential applications in fermented dairy products. In this study, LAB isolated from kefir grains originating from five regions were screened for EPS production and probiotic-related properties. Three strains, Lactiplantibacillus [...] Read more.
Kefir grains are a valuable source of exopolysaccharide (EPS)-producing lactic acid bacteria (LAB) with potential applications in fermented dairy products. In this study, LAB isolated from kefir grains originating from five regions were screened for EPS production and probiotic-related properties. Three strains, Lactiplantibacillus plantarum XZ61, Lactobacillus kefiranofaciens EG10, and Lentilactobacillus kefiri EG12, were selected based on high EPS yield, antimicrobial activity, antioxidant capacity, and tolerance to acidic and bile salt conditions. After optimization, the highest EPS yield (539.57 μg/mL) was obtained from strain EG10.The purified EPS consisted of two molecular weight fractions (≈1.4 and 23~25 kDa) and was rich in mannose (33.38~61.58%). Among the three EPS, EG10-EPS exhibited superior emulsifying and flocculating properties comparable to commercial stabilizers, as well as notable ABTS•+ and hydroxyl radical scavenging activities. Furthermore, co-fermentation of L. kefiranofaciens EG10 with conventional yogurt starter cultures significantly improved exopolysaccharide content, water-holding capacity, texture, and antioxidant activity of fermented milk, particularly in cow milk. These results demonstrate the potential of kefir-derived EPS-producing LAB as natural functional cultures for fermented dairy applications. Full article
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