Recent Advances in Extraction Technologies and Health Benefits of Bioactive Compounds from Foods

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Nutrition".

Deadline for manuscript submissions: 16 November 2026 | Viewed by 2042

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Department of Seafood Science, National Kaohsiung University of Science and Technology, No. 142, Haijhuan Rd., Nanzih District, Kaohsiung City 81157, Taiwan
Interests: enzymes and biocatalysis; brown seaweed; chitin/chitosan; extrusion technology; fish gelatin; fucoidan; silver nanoparticles
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Dear Colleagues,

Recent advances in extraction technologies from food materials have significantly enhanced the efficiency, selectivity, and sustainability of bioactive compound recovery. Innovative methods such as enzyme-assisted extraction (EAE), supercritical fluid extraction (SFE), ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and pulsed electric field (PEF) treatment have gained increasing attention for their ability to minimize solvent usage, reduce processing time, and enlarge the recovery. These techniques not only improve yield and preserve the functional integrity of heat-sensitive nutrients but also align with green chemistry principles. Furthermore, the integration of these technologies with process optimization tools such as response surface methodology (RSM) has enabled greater control over extraction parameters. As consumer demand for natural, health-promoting food ingredients rises, these advanced extraction methods are becoming essential in both research and industrial applications.

Bioactive compounds extracted from foods have garnered increasing interest due to their natural and health-promoting properties. Naturally occurring molecules, such as polysaccharides, polyphenols, flavonoids, carotenoids, phytosterols, and bioactive peptides (BAPs), have been shown to exhibit antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and cardioprotective effects. The regular consumption of food-derived bioactives can help reduce the risk of chronic diseases, including cardiovascular disease, diabetes, and certain types of cancer. Additionally, some compounds play a role in modulating gut microbiota, supporting immune function, and improving metabolic health. As research continues to uncover their mechanisms of action, these bioactive compounds are increasingly being used in the development of functional foods, dietary supplements, and nutraceuticals, offering a natural and holistic approach to disease prevention and health maintenance.

We look forward to receiving your contribution.

Prof. Dr. Chun-Yung Huang
Guest Editor

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Keywords

  • bioactive compounds
  • extraction technologies
  • supercritical fluid extraction
  • ultrasound-assisted extraction
  • microwave-assisted extraction
  • enzyme-assisted extraction
  • functional foods
  • antioxidant activity
  • chronic disease prevention
  • green extraction
  • nutraceuticals
  • pharmaceuticals
  • complementary therapeutic effects
  • biological functions
  • signal transduction pathway
  • response surface methodology
  • mechanisms of action

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Published Papers (1 paper)

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Research

16 pages, 1046 KB  
Article
Optimization of β-Carotene Enrichment of Coconut Oil from Canistel (Pouteria campechiana L.) Using Response Surface Methodology
by Harshaka Maduwantha Jans, Madushi Chathurika Wijerathna, Ganwarige Sumali Nivanthi Fernando and Maryam S. Hafiz
Foods 2025, 14(22), 3947; https://doi.org/10.3390/foods14223947 - 18 Nov 2025
Viewed by 1513
Abstract
Vitamin A deficiency (VAD) affects millions of people around the world, particularly in populations with limited dietary diversity. The present study aimed to develop β-carotene-fortified coconut oil using Pouteria campechiana (Canistel), which is an underutilized tropical fruit rich in β-carotene. A solvent-free fortification [...] Read more.
Vitamin A deficiency (VAD) affects millions of people around the world, particularly in populations with limited dietary diversity. The present study aimed to develop β-carotene-fortified coconut oil using Pouteria campechiana (Canistel), which is an underutilized tropical fruit rich in β-carotene. A solvent-free fortification process was optimized using response surface methodology (RSM) with a central composite design to evaluate the effects of oil percentage (50–100% w/v) and heating temperature (30–60 °C) on β-carotene retention and oil quality. The quadratic model showed excellent fit (R2 = 0.9970; lack of fit p = 0.6815), while optimum conditions were identified at 52.4 °C and 50% (w/w) oil, yielding a predicted β-carotene concentration of 2.22 µg/mL. The fortified oil exhibited significantly higher polyphenolic (17.37 ± 2.04 mg GAE/g), total flavonoid (11.33 ± 0.89 mg QE/g) contents, and antioxidant activity (9.78 ± 0.53 mg TE/g) compared with commercial coconut oil. The optimized oil demonstrated enhanced oxidative stability, reflected by lower peroxide (0.05 ± 0.01 meqO2/kg) and acid values (0.10 ± 0.01 mg KOH/g). The validated quadratic model and optimized process produced a nutritionally enriched, stable coconut oil, supporting its use as a clean-label functional ingredient. These findings highlight the potential of β-carotene-fortified oils to deliver provitamin A and antioxidant benefits. Future studies should focus on evaluating the bioavailability, storage stability, and sensory acceptability of β-carotene enriched coconut oil to confirm its nutritional and commercial potential. Full article
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