Bioactive Phytochemicals and Antioxidants: Exploring Innovative Technology, Functional Properties and Health Benefits for Edible Fungi and Plant-Based Functional Foods

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Nutraceuticals, Functional Foods, and Novel Foods".

Deadline for manuscript submissions: 15 January 2027 | Viewed by 2426

Special Issue Editor


E-Mail Website
Guest Editor
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, China
Interests: natural products; functional foods; polyphenols & antioxidants; bioseparation engineering; industrial applications

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the in-depth exploration of bioactive phytochemicals and antioxidants in edible fungi and plant-based resources, such as β-glucans, terpenoids, phenolic acids, polysaccharides, flavonoids, polyphenols, carotenoids, and so on. These constituents bring multiple health benefits, including immunomodulation, anti-inflammatory, antioxidant, and anticancer effects, and are crucial in fighting against oxidative stress and chronic diseases like diabetes and cardiovascular disorders in vitro or in vivo.

Advanced techniques for food and high-value products made of bioactive phytochemicals and antioxidants in edible fungi and plant-based resources include optimizing the extraction, isolation, purification, and modification of bioactive compounds and adjusting the biosynthesis of bioactive metabolites. Technologies for improving the stability and bioavailability of active ingredients, such as fermentation and nanotechnology-based encapsulation, will be emphasized. Formula optimization and process research for food and high-value products will also be emphasized.

The integration of omics technologies, including genomics, transcriptomics, and metabolomics, aims to uncover the molecular mechanisms behind bioactive compound biosynthesis in fungi and plants. This knowledge can drive the development of precision breeding strategies and engineered strains with better bioactive profiles. With the growing popularity of plant-based meat alternatives and myco-protein products due to sustainable and ethical food demands, this area is also a key focus for innovation.

We welcome contributions from scientists, industry professionals, and policymakers. By gathering cutting-edge research, this Special Issue will be an essential resource, facilitating interdisciplinary collaboration and unlocking the full potential of edible fungi and plant-based functional foods.

Dr. Hua Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive phytochemicals
  • antioxidants
  • edible fungi
  • plant-based functional foods
  • health benefits
  • omics technologies
  • bioavailability
  • sustainable food

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

28 pages, 7489 KB  
Article
Chemical Components and Hypouricemic Activity Monitoring of Astragali radix-Huaier During Fermentation Processing Using High-Resolution Mass Spectrometry Combined with Untargeted Metabolomics
by Zhicheng Yin, Jie Li, Shuyi Song, Hong Wang, Tianmei Niu, Xiaojie Wang, Shengqian Sun and Jiayu Zhang
Foods 2026, 15(10), 1758; https://doi.org/10.3390/foods15101758 - 15 May 2026
Viewed by 203
Abstract
Recent evidence highlights the therapeutic potential of Astragali radix-Huaier fermentation products for hyperuricemia treatment, although the dynamics of the fermentation process remain poorly understood. This study employed high-resolution mass spectrometry and untargeted metabolomics for real-time monitoring of chemical components and hypouricemic activity [...] Read more.
Recent evidence highlights the therapeutic potential of Astragali radix-Huaier fermentation products for hyperuricemia treatment, although the dynamics of the fermentation process remain poorly understood. This study employed high-resolution mass spectrometry and untargeted metabolomics for real-time monitoring of chemical components and hypouricemic activity throughout fermentation. The results revealed significant alterations in the chemical composition, with distinct sample separations observed on days 7, 14, 21, and 28. A total of 33 differential components were identified, including 20 flavonoids and 13 saponins, eight of which showed notable changes. Polysaccharides and saponins were found to correlate positively with the uric acid-lowering effect. On day 21, the levels of total polysaccharides and cycloastragenol-6-glucoside, a saponin derivative, peaked, coinciding with the highest hypouricemic activity of the Astragalus fungal fermentation products. This study provides the first evidence of dynamic changes in the chemical profile and pharmacological activity of Astragali radix-Huaier during fermentation, paving the way for optimizing fermentation processes and developing medicinal and dietary products based on Astragali radix. Full article
Show Figures

Figure 1

15 pages, 1731 KB  
Article
Structural Identification and Antioxidant Activity of Pine Nut Peptide–Zinc Chelate Complex
by Kexin Yang, Xiaotong Zhang, Jiayu Zhang and Zhi Zhang
Foods 2026, 15(2), 359; https://doi.org/10.3390/foods15020359 - 19 Jan 2026
Viewed by 597
Abstract
To achieve the high-value utilization of pine nut resources, a novel zinc supplement was developed in this study. Pine nut protein was enzymatically hydrolyzed to prepare pine nut peptides (PP), which were subsequently chelated with zinc ions to form pine nut peptide–zinc chelate [...] Read more.
To achieve the high-value utilization of pine nut resources, a novel zinc supplement was developed in this study. Pine nut protein was enzymatically hydrolyzed to prepare pine nut peptides (PP), which were subsequently chelated with zinc ions to form pine nut peptide–zinc chelate (PZn). Under optimized conditions, the zinc chelation rate of PZn reached 60.18 ± 1.77%. Peptidomic analysis revealed that PZn is composed of a select group of peptides predominantly characterized by low molecular weight (80.65 ± 1.47% < 1 kDa) and enrichment in aspartic acid, glutamic acid, and cysteine, indicating a self-selective chelation process. Comprehensive characterization via multiple techniques confirmed that zinc ions coordinate with carboxyl, hydroxyl, and thiol groups on these peptides, leading to charge neutralization, disruption of hydrogen-bonding networks, and peptide aggregation. Furthermore, bioactivity prediction of the PZn-constituting peptides revealed high intrinsic antioxidant potential, which corroborated the experimental results, showing that PZn exhibited significantly enhanced radical scavenging capacity compared to PP. These findings demonstrate that PZn possesses excellent zinc-binding capability and antioxidant activity, suggesting its potential as a novel zinc supplement, with its efficacy rooted in its specific molecular composition. Full article
Show Figures

Figure 1

20 pages, 2482 KB  
Article
Antioxidant Performance and Characterization Comparison of Carbon Dots Derived from Agricultural Waste Pineapple Peel
by Zhaoqi Pan, Yiyang Zhou, Binghong Ji, Qining Liu and Ziluan Fan
Foods 2026, 15(2), 189; https://doi.org/10.3390/foods15020189 - 6 Jan 2026
Cited by 2 | Viewed by 1069
Abstract
This study prepared carbon dots (CDs) from agricultural waste pineapple peel via an eco-friendly microwave method, optimizing their performance through copper ion and chitosan doping. Multiple characterization techniques and performance tests were employed for systematic analysis. Antioxidant assays revealed that PP-CDs have excellent [...] Read more.
This study prepared carbon dots (CDs) from agricultural waste pineapple peel via an eco-friendly microwave method, optimizing their performance through copper ion and chitosan doping. Multiple characterization techniques and performance tests were employed for systematic analysis. Antioxidant assays revealed that PP-CDs have excellent concentration-dependent free radical scavenging activity: the DPPH IC50 values of Pineapple Peel Carbon Dots (PP-CDs), Copper-Doped Pineapple Peel Carbon Dots (Cu-PP-CDs) and Chitosan-Doped Pineapple Peel Carbon Dots (CS-PP-CDs) are 0.79, 0.95 and 0.98 mg/mL, while their ABTS IC50 values are 0.22, 0.40 and 0.26 mg/mL, respectively. Antibacterial tests showed modified CDs have enhanced activity: Cu-PP-CDs exhibit inhibition zones of 23.1 ± 0.13 mm (E. coli) and 17.3 ± 0.05 mm (S. aureus) with MICs of 2.5 and 5.0 mg/mL, while CS-PP-CDs have respective zones of 12.8 ± 0.08 mm and 16.3 ± 0.12 mm with a 5.0 mg/mL MIC for both strains. All CDs present a quasi-spherical morphology and emit yellow fluorescence under UV excitation, with PP-CDs showing the strongest intensity. This study provides technical support for high-value utilization of pineapple peel and development of multifunctional CDs, which have food field potential but face large-scale production and toxicological evaluation challenges. Full article
Show Figures

Graphical abstract

Back to TopTop