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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases

edited by

Liangjing Lu

submission deadline 31 May 2026 | Viewed by 156 | Submission Open

Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Imaging Diagnosis of Oral and Maxillofacial Diseases

edited by

Julien Issa

Marta Dyszkiewicz-Konwińska

and Erwin Berkhout

submission deadline 31 May 2026 | Viewed by 145 | Submission Open

Keywords: oral radiology; digital dentistry; dental imaging; diagnosis; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

The Application of Large Language Models (LLMs) and Vision-Language Models (VLMs) in Healthcare

edited by

Shuo-Chen Chien

and

Wen-Shan Jian

submission deadline 31 May 2026 | Viewed by 137 | Submission Open

Keywords: large language models (LLMs); vision-language models (VLMs); artificial intelligence in healthcare; natural language processing (NLP); clinical decision support systems; medical imaging analysis; multimodal learning; healthcare data analytics; patient-centered care; ethical AI in medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Ocular Surface Alterations in Eyelid Malpositions: Pathophysiology, Diagnostic Tools, and Therapeutic Approaches

edited by Massimiliano Serafino and

Alessandra Di Maria

submission deadline 31 May 2026 | Viewed by 133 | Submission Open

Keywords: lid malpositions and ocular surface disorders; dry eye syndrome; exposure keratopathy; tear film instability; anterior segment imaging; lid surgery outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Treatment of Gynecological Infections

edited by

Gilbert Donders

submission deadline 31 May 2026 | Viewed by 123 | Submission Open

Keywords: genital infections; vaginal microbiome; sexually transmitted infections; diagnostic microscopy; antibiotic resistance

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Brain Radiation Necrosis: Emerging Insights in Pathophysiology, Diagnosis, and Management

edited by

Nam P. Nguyen

and Gokoulakrichenane Loganadane

submission deadline 31 May 2026 | Viewed by 113 | Submission Open

Keywords: brain radiation necrosis; radiation therapy; multimodal imaging; differential diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases, 2nd Edition

edited by

Thierry Naas

Ranjan Ramasamy

and

Ilana Lopes Baratella da Cunha Camargo

submission deadline 31 May 2026 | Viewed by 110 | Submission Open

Keywords: molecular diagnostics; infectious diseases; microorganisms; virus detection; antibiotic resistance; bacterial strains

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostic Imaging and Radiotherapy for Hepato-Biliary and Pancreatic Tumors

edited by

Michele Fiore

, Gian Marco Petrianni and Gabriele D'Ercole

submission deadline 31 May 2026 | Viewed by 109 | Submission Open

Keywords: hepato-biliary tumors; pancreatic tumors; diagnostic imaging; radiotherapy; SBRT; IGRT; adaptive radiotherapy; imaging biomarkers; multimodal therapy; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in HIV Diagnostics and Monitoring

edited by Nuno Taveira

submission deadline 31 May 2026 | Viewed by 101 | Submission Open

Keywords: HIV disease; HIV diagnostics; HIV testing; HIV monitoring; point-of-care testing; next-generation sequencing; biomarkers

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advanced Meta-Analytical Approaches and Novel Diagnostic Technologies in Cardiovascular Medicine

edited by

Raheel Ahmed

submission deadline 31 May 2026 | Viewed by 94 | Submission Open

Keywords: meta-analysis; evidence synthesis; cardiovascular diagnosis; clinical evidence; evidence-based medicine; diagnostic accuracy; systematic review

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Collaborative Robotics and Total Laboratory Automation in Clinical Diagnostics

edited by Robert S. Ohgami

submission deadline 31 May 2026 | Viewed by 93 | Submission Open

Keywords: collaborative robotics; total laboratory automation (TLA); diagnostic medicine; clinical validation ; robotic liquid handling ; digital pathology ; clinical microbiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advances in the Diagnosis and Management of Sports Injuries

edited by

Alberto Grassi

submission deadline 31 May 2026 | Viewed by 92 | Submission Open

Keywords: sport injuries; sport traumatology; arthroscopy; surgery; joints

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Achievements in Neuroimaging

edited by

Malek Makki

submission deadline 31 May 2026 | Viewed by 84 | Submission Open

Keywords: developing and aging brain; neuropathology; neuroplasticity; neuropsychology; functions and structures; metabolism and perfusion; machine learning and AI; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk Factors, Incidence, and Outcome of Stroke

edited by Emir Veledar

submission deadline 31 May 2026 | Viewed by 80 | Submission Open

Keywords: stroke prevention; acute stroke management; post-acute stroke care; predictive modeling; risk stratification; neuroimaging; biomarkers; early detection; prognostic evaluation; diagnostic algorithms; cerebral infarction; intracranial hemorrhage; ischemic stroke subtypes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

From Data to Decisions: Deep Learning in Clinical Diagnostics

edited by Jianfu Li

submission deadline 31 May 2026 | Viewed by 75 | Submission Open

Keywords: deep learning; clinical diagnostics; medical AI; diagnostic accuracy; clinical decision support; medical imaging; biomarker discovery; healthcare implementation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Asthma

edited by

Padukudru Anand Mahesh

submission deadline 31 May 2026 | Viewed by 70 | Submission Open

Keywords: asthma; diagnosis; management; biomarkers; biologics; phenotypes; endotypes; precision medicine; digital health; autoimmune; cytokine; interleukin

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Options and Treatment Strategies for Neurological Disorders

edited by

Julia Koehn

and Jenny Stritzelberger

submission deadline 31 May 2026 | Viewed by 69 | Submission Open

Keywords: neuroscience; diagnostic tools; point-of-care testing; prehospital care; emergency medicine; rapid and accurate diagnosis; treatment strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Latest Advances in Ophthalmic Imaging: Second Edition

edited by

Slawomir Teper

and

Gawęcki Maciej

submission deadline 31 May 2026 | Viewed by 68 | Submission Open

Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Inflammation and Infection Imaging: 2nd Edition

edited by

Giorgio Treglia

submission deadline 31 May 2026 | Viewed by 54 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 May 2026 | Viewed by 49 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Urological Diagnostics: Emerging Technologies and Innovative Approaches

edited by

José Enrique Robles-García

submission deadline 31 May 2026 | Viewed by 38 | Submission Open

Keywords: urological diseases; diagnostic imaging; biomarkers; molecular diagnostics; prostate cancer diagnosis; renal disease diagnosis; artificial intelligence in urology; noninvasive diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Trends and Novelties in Bone Imaging

edited by Kamyar Moradi

submission deadline 31 May 2026 | Viewed by 37 | Submission Open

Keywords: artificial intelligence; biomarkers; bone imaging; bone aging; osteoporosis; osteoarthritis; quantitative imaging; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Diagnostic and Prognostic Tools in Gynecological Cancer

edited by

Ahmad Sayasneh

submission deadline 31 May 2026 | Viewed by 37 | Submission Open

Keywords: gynaecological cancer; diagnostic imaging; artificial intelligence; molecular biomarkers; prognostic models; surgical navigation; precision oncology; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Interdisciplinary Approaches to Improve Cardiovascular Outcomes

edited by

Mihaela Hostiuc

submission deadline 31 May 2026 | Viewed by 21 | Submission Open

Keywords: cardiovascular disease; prevention; risk factors; cardiovascular outcomes; interdisciplinarity; burden of disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Data Science and Artificial Intelligence in Laboratory Medicine

edited by

Fernando Marques-Garcia

submission deadline 1 Jun 2026 | Viewed by 114 | Submission Open

Keywords: artificial intelligence; data science; algorithm; laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Insights into the Diagnosis of Gynecological Diseases

edited by

Dah Ching Ding

submission deadline 30 Jun 2026 | 5 articles | Viewed by 24178 | Submission Open

Keywords: gynecological diseases; precision medicine; molecular diagnostics; artificial intelligence; biomarkers; next-generation sequencing; imaging technologies; big data

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

3rd Edition: AI/ML-Based Medical Image Processing and Analysis

edited by

Ghazanfar Latif

and

Jaafar Alghazo

submission deadline 30 Jun 2026 | 12 articles | Viewed by 12192 | Submission Open

Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 30 Jun 2026 | 7 articles | Viewed by 9290 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Clinical Decision Support—2nd Edition

edited by

Qingqing Mao

submission deadline 30 Jun 2026 | 5 articles | Viewed by 8309 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support; predictive modeling; patient monitoring; diagnostic support; treatment recommendation; safety and privacy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Imaging for Radiation Oncology

edited by

Sara Haseli

and Arash Azhideh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 7611 | Submission Open

Keywords: radiation oncology; diagnostic imaging; artificial intelligence; radiomics; tumor detection; molecular imaging; treatment planning; radiogenomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

PET/CT Imaging in Oncology: Clinical Advances and Perspectives

edited by

Francesco Lanfranchi

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3453 | Submission Open

Keywords: PET/CT imaging; molecular imaging; oncology; cancer diagnosis; precision oncology; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

edited by Otilia Țica

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3440 | Submission Open

Keywords: cardiovascular disease; biomarkers; precision medicine; diagnostics; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Heart Failure: Clinical Diagnosis, Treatment, and Prognosis

edited by

Massimo Mapelli

and Irene Mattavelli

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3141 | Submission Open

Keywords: heart failure; clinical diagnosis; treatment advances; precision medicine; exercise evaluation; CPET

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy

edited by

Caterina Carollo

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2711 | Submission Open

Keywords: kidney; nephrology; ultrasounds; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Laboratory Analysis and Diagnostics

edited by Ivana Lapić

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2671 | Submission Open

Keywords: laboratory analysis; diagnostics; analytical techniques; diagnostic methods

(This special issue belongs to the Section Clinical Laboratory Medicine)

Applications of Artificial Intelligence in Orthopedics

edited by Zhonghai Li

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1791 | Submission Open

Keywords: artificial intelligence; orthopedics; medical diagnosis; image analysis; predictive modeling

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Neurodiagnostics in Public Health: Cognitive Decline, Mental Health, and Emerging Technologies

edited by

Evgenia Gkintoni

and

Apostolos Vantarakis

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1722 | Submission Open

Keywords: neurocognitive disorders; dementia; mild cognitive impairment (MCI); neuropsychiatric diseases; biomarkers; imaging; artificial intelligence; digital diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Fetal Doppler Assessment: From Basic Research to Clinical Practice

edited by Luís Guedes-Martins

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1717 | Submission Open

Keywords: fetal Doppler; fetal growth restriction; preeclampsia; fetal-placental hemodynamics; fetal death; placental abruption; placental circulation; fetal cerebral circulation; fetal hepatic circulation; fetal heart function

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Plastic Surgery: Diagnosis, Management and Prognosis

edited by

Konstantinos Seretis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1567 | Submission Open

Keywords: plastic surgery; breast reconstruction; skin graft; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Adverse Drug Reactions in Precision Medicine and Big Data

edited by

Elena Ramírez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1465 | Submission Open

Keywords: adverse drug reactions; pharmacovigilance; drug safety; risk factors; causality assessment; big data; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Photon-Counting CT in Clinical Application

edited by Philipp Gruschwitz

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1219 | Submission Open

Keywords: protocol development and optimization; spectral imaging; tissue characterization; lesion classification; benefits of special resolution; radiation dose optimization; contrast agent

(This special issue belongs to the Section Medical Imaging and Theranostics)

Early Diagnosis of Sepsis: Current Status and Challenges

edited by

Andrea Piccioni

and

Gloria Rozzi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1177 | Submission Open

Keywords: sepsis; early diagnosis of sepsis; biomarkers; sepsis mortality; serum presepsin; SOFA score

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition

edited by

Mohammad Shahadat Hossain

submission deadline 30 Jun 2026 | 1 articles | Viewed by 881 | Submission Open

Keywords: Alzheimer’ s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Generative AI and Digital Twins in Diagnostics

edited by

Sean Benson

submission deadline 30 Jun 2026 | Viewed by 751 | Submission Open

Keywords: digital twins; electronic health record; generative AI; personalized medicine; clinical practice; simulation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Microbial Infections and Critical Care Medicine: Diagnosis and Management, 2nd Edition

edited by Eleni K. Mouloudi,

Serafeim Chrysovalantis Kotoulas

and Eleni Massa

submission deadline 30 Jun 2026 | Viewed by 659 | Submission Open

Keywords: microbial infections; superbugs; antimicrobial resistance; multi-drug resistance; critical care; diagnosis; management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 30 Jun 2026 | 1 articles | Viewed by 535 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Retinopathy—2nd Edition

edited by

Joanna Gołȩbiewska

submission deadline 30 Jun 2026 | 1 articles | Viewed by 449 | Submission Open

Keywords: diabetic retinopathy; hypertensive retinopathy; inherited retinal diseases; imaging; OCT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Dermatologic Diagnostics: Integrating Dermoscopy, Imaging, and Non-Surgical Therapies

edited by

Carmen Cantisani

and

Norbert Kiss

submission deadline 30 Jun 2026 | Viewed by 346 | Submission Open

Keywords: dermoscopy; clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Biomedical Optics)

Laboratory Investigations in Nephrology

edited by

Marijn Speeckaert

submission deadline 30 Jun 2026 | Viewed by 208 | Submission Open

Keywords: nephrology; laboratory diagnostics; novel biomarkers; chronic kidney disease; renal pathology; artificial intelligence and machine learning

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Pulmonary Adenocarcinoma

edited by

Cesar A. Moran

submission deadline 30 Jun 2026 | Viewed by 196 | Submission Open

Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 451-500 on page 10 of 14.

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