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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 5 articles | Viewed by 3370 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Decoding Complexity in Traumatic Injury Diagnosis: Forensic Approaches

edited by

Alice Chiara Manetti

and

Fabio Del Duca

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3330 | Submission Open

Keywords: traumatology; forensic pathology; vitality; post-mortem examination; trauma diagnosis; forensic imaging; individual protections; job security; histology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3263 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome–host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

(Bio)sensors for Medical Diagnostics

edited by

Mihaela Badea

Akhtar Hayat

and Sehrish Bilal

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2910 | Submission Open

Keywords: sensors and biosensors; medical diagnostics; biomarker detection; point-of-care testing; lab-on-a-chip; wearable health technology; nanotechnology; signal transduction; early disease detection; clinical monitoring

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnosis of Viral Respiratory Infections, 2nd Edition

edited by

Federica Novazzi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2872 | Submission Open

Keywords: respiratory tract infections; lower respiratory tract infections (LRTIs); upper respiratory tract infections (URTIs); whole-genome sequencing (WGS); immunological techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Clinical Prognostic and Predictive Biomarkers, 4th Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2769 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Sports Medicine: Diagnosis and Management

edited by Anca Ionescu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2736 | Submission Open

Keywords: sports medicine; sports cardiology; exercise physiology; artificial intelligence; athlete health; performance monitoring; biomarkers; sports nutrition; injury prevention; rehabilitation; wearable technology; clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advancements in Maternal–Fetal Medicine: 3rd Edition

edited by

Elena Bernad

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2584 | Submission Open

Keywords: maternal–fetal medicine; high-risk pregnancy; prenatal diagnostics; psychological distress in pregnancy; anxiety and depression; stress-related disorders; biomarkers; perinatal morbidity and mortality; translational diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Treatment of Otolaryngology Diseases

edited by Lichun Hsieh

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2544 | Submission Open

Keywords: otolaryngology; diagnostic imaging; minimally invasive surgery; precision medicine; head and neck diseases; clinical management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Anatomy and Diagnosis in 2026

edited by Ji-Hyun Lee

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2543 | Submission Open

Keywords: clinical anatomy; radiological anatomy; applied anatomy; anatomical variations; pathoanatomy; artificial intelligence in anatomy; anatomical research innovation; anatomical education

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2504 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2379 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2188 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2095 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

AI-Powered Ophthalmic Diagnostics: From Image Segmentation to Disease Classification

edited by

Yanwu Xu

Weihua Yang

and

Huihui Fang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2068 | Submission Open

Keywords: ophthalmic artificial intelligence; medical image segmentation; disease classification; ocular imaging; deep learning and foundation models; explainable AI (XAI); clinical translation in ophthalmology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Technologies for Lung Disease Detection and Clinical Assessment

edited by Scott Matson and

Joshua Jay Reicher

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2043 | Submission Open

Keywords: medical imaging; artificial intelligence (AI); radiology; machine learning (ML)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Eye Disease, Fifth Edition

edited by

Jae-Ho Han

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2043 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Diagnosis and Management of Liver Diseases

edited by

Jiang Liu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2026 | Submission Open

Keywords: primary liver cancer; metastatic liver cancer; liver transplantation; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence, 2nd Edition

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1997 | Submission Open

Keywords: biomarkers; diagnosis; personalized medicine; therapeutic strategies; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Oral and Maxillofacial Surgery: Diagnosis and Management

edited by Kenji Yamagata

submission deadline 31 Dec 2026 | 4 articles | Viewed by 1970 | Submission Open

Keywords: oral and maxillofacial surgery; oral diseases; oral cancer; jaw deformity; orthognathic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Whole-Body PET/CT: From Diagnosis to Prognosis

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1906 | Submission Open

Keywords: whole-body PET/CT; diagnosis; prognosis; human diseases; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic and Operative Hysteroscopy, 2nd Edition

edited by

Panagiotis Christopoulos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1803 | Submission Open

Keywords: hysteroscopy; diagnosis; technique; malformation; uterus; endometrial; anomaly; minimally invasive; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1769 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Women’s Cardiovascular Health: Advances in Diagnosis, Screening, and Risk Prediction

edited by

Jasjit S. Suri

and

Luca Saba

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1766 | Submission Open

Keywords: artificial intelligence; women’s cardiovascular health; diagnosis; screening; risk prediction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Hepatitis

edited by

Qi Wang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1697 | Submission Open

Keywords: viral hepatitis; hepatitis B virus hepatitis; drug-induced liver injury; autoimmune hepatitis; metabolic-associated fatty liver disease; alcoholic liver disease; diagnosis; follow-up management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1596 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnostics and Management in the ICU

edited by

Silvia De Rosa

and Sergio Lassola

submission deadline 31 Dec 2026 | 4 articles | Viewed by 1551 | Submission Open

Keywords: intensive care unit; hemodynamic monitoring; acute kidney injury; sepsis and septic shock; clinical diagnostics; predictive biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Chronic Kidney Diseases: Diagnosis, Management, and Prognosis

edited by

Xujie Zhou

submission deadline 31 Dec 2026 | Viewed by 1540 | Submission Open

Keywords: chronic kidney diseases; IgA nephropathy; biomarkers; molecular mechanisms; therapeutic innovation; personalized medicine; translational research

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Fetal Diagnosis and Therapy: 2nd Edition

edited by Elisa Montaguti and Camilla Dionisi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1426 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1356 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1326 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Advances in Orthodontics and Dentistry

edited by

Antonino Lo Giudice

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1323 | Submission Open

Keywords: CBCT facial scanning; oral imaging; orthodontics; digital dentistry; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis, Prognosis, and Management of the Musculoskeletal System

edited by

Massimiliano Leigheb

Alessandro de Sire

and Cesar de Cesar Netto

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1316 | Submission Open

Keywords: musculoskeletal system; diagnostic tools; prognosis; artificial intelligence; augmented reality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases

edited by

Liangjing Lu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1269 | Submission Open

Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cancer Diagnosis and Intervention

edited by Vlad Alexandru Gâta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1226 | Submission Open

Keywords: diagnostic; precision oncology; artificial intelligence; radiomics; molecular biomarkers; interventional oncology; personalized medicine; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Prostate Cancer: Innovations in Diagnosis and Risk Stratification

edited by Biren Saraiya

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1216 | Submission Open

Keywords: prostate cancer; diagnostics; therapeutics; molecular targets; Prostate Specific Membrane Antigen (PSMA); risk stratification; radioligand therapy; multimodal therapy; clinical guidelines

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Accurate Diagnosis and Management of Infectious and Respiratory Diseases

edited by

Marco Goeijenbier

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1187 | Submission Open

Keywords: infectious and respiratory diseases; viral and bacterial pathogens; multiplex molecular panels; rapid diagnostic tests; intensive care units

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Medical Microbiology and Infection: Diagnosis and Management

edited by

Hsinyao Wang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 984 | Submission Open

Keywords: medical microbiology; infectious diseases; diagnostic microbiology; infection management; antimicrobial susceptibility testing; non‑antibiotic therapies; clinical microbiology; diagnostic innovation

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 31 Dec 2026 | 1 articles | Viewed by 957 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Laboratory Diagnosis—2nd Edition

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 915 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Computed Tomography Imaging in Medical Diagnosis, Third Edition

edited by

Fabio Sandomenico

submission deadline 31 Dec 2026 | 2 articles | Viewed by 910 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Analytical Techniques in Microbial and Biomarker Research

edited by Hariom Yadav,

Siddabasave Gowda B. Gowda

and

Shu-Ping Hui

submission deadline 31 Dec 2026 | Viewed by 767 | Submission Open

Keywords: LC-MS; GC-MS; NMR; spectroscopy; microbiology; clinical; diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Precision Oncology: Integrating Histopathology, Immunohistochemistry, and Molecular Diagnostics

edited by

Tomonori Kawasaki

submission deadline 31 Dec 2026 | 1 articles | Viewed by 719 | Submission Open

Keywords: biomarker; cancer; carcinoma; cytology; diagnosis; fluorescence in situ hybridization; gene; growth factor receptor; histology; hormone receptor; immunohistochemistry; molecular pathology; neoplasm; next-generation sequencing; oncology; pathology; PCR; prognosis; treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

From Innovation to Clinical Practice: Anticipating the New Era of AI-Driven Laboratory Medicine

edited by Edda Russo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 676 | Submission Open

Keywords: artificial intelligence (AI); laboratory medicine; data integration; clinical validation; diagnostic strategies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Gastrointestinal Endoscopy: Diagnostic Applications and Safety Evaluation

edited by

Giacomo Emanuele Maria Rizzo

Lucía Guilabert

and Sara Nikolic

submission deadline 31 Dec 2026 | 1 articles | Viewed by 671 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; luminal endoscopy; procedural safety; risk assessment; adverse events; sedation protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

From Early Diagnosis to Therapy Response: Machine Learning Driven Biomarker Discovery

edited by Wenjie Shi and Rudy Leon De Wilde

submission deadline 31 Dec 2026 | 1 articles | Viewed by 642 | Submission Open

Keywords: machine learning; biomarker discovery; early diagnosis; liquid biopsy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Dec 2026 | Viewed by 590 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Deep Learning and Large Models in Ophthalmic Innovations

edited by

Yanwu Xu

Weihua Yang

and Huihui Fang

submission deadline 31 Dec 2026 | Viewed by 493 | Submission Open

Keywords: Artificial Intelligence in ophthalmology; multimodal learning; foundation models; ophthalmic imaging; eye disease diagnosis and treatment

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 31 Dec 2026 | Viewed by 491 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Pulmonary Adenocarcinoma

edited by

Cesar A. Moran

submission deadline 31 Dec 2026 | Viewed by 488 | Submission Open

Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 251-300 on page 6 of 13.

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