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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 31 May 2026 | 2 articles | Viewed by 2467 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 31 May 2026 | 2 articles | Viewed by 2398 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Histopathology in Cancer Diagnosis and Prognosis—2nd Edition

edited by

Christina Magkou

submission deadline 31 May 2026 | 1 articles | Viewed by 2383 | Submission Open

Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

edited by

Elisabeth Kapaki

and

Efstratios-Stylianos Pyrgelis

submission deadline 31 May 2026 | 1 articles | Viewed by 2083 | Submission Open

Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis of Digestive Diseases

edited by Noriaki Manabe

submission deadline 31 May 2026 | 2 articles | Viewed by 1904 | Submission Open

Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions

edited by

Ishith Seth

submission deadline 31 May 2026 | 1 articles | Viewed by 1830 | Submission Open

Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Advances and Applications in Neuroradiology: 2nd Edition

edited by

Houman Sotoudeh

submission deadline 31 May 2026 | 1 articles | Viewed by 1575 | Submission Open

Keywords: neuroradiology; advanced imaging; susceptibility-weighted imaging (SWI); diffusion tensor imaging (DTI); functional MRI (fMRI); CT perfusion; MR perfusion; MR spectroscopy; PET; molecular imaging; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Musculoskeletal Disorders: Diagnosis, Management, and Rehabilitation, 2nd Edition

edited by

Antonio Stecco

submission deadline 31 May 2026 | 1 articles | Viewed by 1517 | Submission Open

Keywords: musculoskeletal disorders; pain; disability; diagnosis; interventions; rehabilitation strategies; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in Diagnostic Bronchoscopy

edited by

Kassem Harris

submission deadline 31 May 2026 | 1 articles | Viewed by 1051 | Submission Open

Keywords: diagnostic bronchoscopy; advanced imaging techniques; interventional bronchoscopy; minimally invasive techniques

(This special issue belongs to the Section Biomedical Optics)

Emerging Predictive Biomarkers in Breast Cancer

edited by

Giuseppina Rosaria Rita Ricciardi

and Maria Vita Sanò

submission deadline 31 May 2026 | 1 articles | Viewed by 1049 | Submission Open

Keywords: breast cancer; HER2-positive; TNBC; ER+; HER2-negative; HER2-low; PD-L1; 18F-FES PET; hormonotherapy; immunotherapy; immune checkpoint inhibitors; liquid biopsy; circulating tumor cells; ctDNA; antibody drug conjugates; PARP inhibitors; CDK4/6 inhibitors; predictive biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Cardiometabolic Disease: Diagnosis and Management

edited by Muhammad Shariq Usman

submission deadline 31 May 2026 | 1 articles | Viewed by 990 | Submission Open

Keywords: cardiometabolic disease; diagnosis; management; diabetes; obesity; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advanced Diagnostic Approaches in Cardiovascular Diseases: From Imaging to Biomarkers

edited by

Ovidiu Mitu

and

Lucia Stefania Magda

submission deadline 31 May 2026 | 1 articles | Viewed by 690 | Submission Open

Keywords: medical diagnosis; cardiovascular diseases; imaging; biomarkers; AI-driven analytics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Diagnosis and Management of Metabolic Bone Disease

edited by Liming Xiong

submission deadline 31 May 2026 | 1 articles | Viewed by 665 | Submission Open

Keywords: metabolic bone disease; bone turnover markers; maintenance of bone homeostasis; multiorgan– bone axis; fracture risk assessment; diabetic osteopathy; precision management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advanced Diagnosis and Integrated Management of Bone and Soft Tissue Tumors

edited by Tiao Lin

submission deadline 31 May 2026 | 1 articles | Viewed by 419 | Submission Open

Keywords: musculoskeletal neoplasms; diagnostic imaging; molecular pathology; multidisciplinary treatment; personalized medicine; translational research; multidisciplinary collaboration

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 31 May 2026 | Viewed by 404 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical and Laboratory Diagnosis of Inherited Metabolic Diseases in Children

edited by

Patryk Lipiński

submission deadline 31 May 2026 | 1 articles | Viewed by 265 | Submission Open

Keywords: newborn screening; selective screening; inherited metabolic disease; biochemical diagnostics; biomarkers; molecular analysis; next-generation sequencing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advancements of Molecular Biomarkers in Cancer, 2nd Edition

edited by Giuseppe Nicolò Fanelli

submission deadline 31 May 2026 | Viewed by 248 | Submission Open

Keywords: molecular biomarkers; cancer research; precision medicine; tumor profiling; genomic signatures; personalized oncology; biomarker discovery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Medical Imaging: Innovations and Diagnostic Applications

edited by

Ayman El-Baz

, Moumen Elmelegy,

Asem M. Ali

and

Ali H. Mahmoud

submission deadline 31 May 2026 | Viewed by 133 | Submission Open

Keywords: medical imaging; artificial intelligence; disease diagnosis; radiomics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Inflammatory Respiratory Diseases

edited by Kęstutis Malakauskas and

Andrius Januskevicius

submission deadline 31 May 2026 | Viewed by 130 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease; inflammatory respiratory diseases; inflammation; biomarkers; respiratory diagnostics; anti-inflammatory therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ocular Surface Alterations in Eyelid Malpositions: Pathophysiology, Diagnostic Tools, and Therapeutic Approaches

edited by Massimiliano Serafino and

Alessandra Di Maria

submission deadline 31 May 2026 | Viewed by 116 | Submission Open

Keywords: lid malpositions and ocular surface disorders; dry eye syndrome; exposure keratopathy; tear film instability; anterior segment imaging; lid surgery outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Treatment of Gynecological Infections

edited by

Gilbert Donders

submission deadline 31 May 2026 | Viewed by 87 | Submission Open

Keywords: genital infections; vaginal microbiome; sexually transmitted infections; diagnostic microscopy; antibiotic resistance

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Brain Radiation Necrosis: Emerging Insights in Pathophysiology, Diagnosis, and Management

edited by

Nam P. Nguyen

and Gokoulakrichenane Loganadane

submission deadline 31 May 2026 | Viewed by 86 | Submission Open

Keywords: brain radiation necrosis; radiation therapy; multimodal imaging; differential diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Ultrasound Imaging in Clinical Diagnosis

edited by

Jinbum Kang

submission deadline 31 May 2026 | Viewed by 84 | Submission Open

Keywords: diagnostic ultrasound imaging and systems; doppler ultrasound techniques and applications; elastography for tissue characterization; contrast-enhanced ultrasound (CEUS); artificial intelligence in diagnostic ultrasound; point-of-care ultrasound (POCUS); ultrasound-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in HIV Diagnostics and Monitoring

edited by Nuno Taveira

submission deadline 31 May 2026 | Viewed by 73 | Submission Open

Keywords: HIV disease; HIV diagnostics; HIV testing; HIV monitoring; point-of-care testing; next-generation sequencing; biomarkers

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostic Imaging and Radiotherapy for Hepato-Biliary and Pancreatic Tumors

edited by

Michele Fiore

, Gian Marco Petrianni and Gabriele D'Ercole

submission deadline 31 May 2026 | Viewed by 72 | Submission Open

Keywords: hepato-biliary tumors; pancreatic tumors; diagnostic imaging; radiotherapy; SBRT; IGRT; adaptive radiotherapy; imaging biomarkers; multimodal therapy; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Meta-Analytical Approaches and Novel Diagnostic Technologies in Cardiovascular Medicine

edited by

Raheel Ahmed

submission deadline 31 May 2026 | Viewed by 69 | Submission Open

Keywords: meta-analysis; evidence synthesis; cardiovascular diagnosis; clinical evidence; evidence-based medicine; diagnostic accuracy; systematic review

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases, 2nd Edition

edited by

Thierry Naas

Ranjan Ramasamy

and

Ilana Lopes Baratella da Cunha Camargo

submission deadline 31 May 2026 | Viewed by 69 | Submission Open

Keywords: molecular diagnostics; infectious diseases; microorganisms; virus detection; antibiotic resistance; bacterial strains

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Collaborative Robotics and Total Laboratory Automation in Clinical Diagnostics

edited by Robert S. Ohgami

submission deadline 31 May 2026 | Viewed by 65 | Submission Open

Keywords: collaborative robotics; total laboratory automation (TLA); diagnostic medicine; clinical validation ; robotic liquid handling ; digital pathology ; clinical microbiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Achievements in Neuroimaging

edited by

Malek Makki

submission deadline 31 May 2026 | Viewed by 64 | Submission Open

Keywords: developing and aging brain; neuropathology; neuroplasticity; neuropsychology; functions and structures; metabolism and perfusion; machine learning and AI; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in the Diagnosis and Management of Sports Injuries

edited by

Alberto Grassi

submission deadline 31 May 2026 | Viewed by 60 | Submission Open

Keywords: sport injuries; sport traumatology; arthroscopy; surgery; joints

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Imaging Diagnosis of Oral and Maxillofacial Diseases

edited by

Julien Issa

Marta Dyszkiewicz-Konwińska

and Erwin Berkhout

submission deadline 31 May 2026 | Viewed by 57 | Submission Open

Keywords: oral radiology; digital dentistry; dental imaging; diagnosis; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk Factors, Incidence, and Outcome of Stroke

edited by Emir Veledar

submission deadline 31 May 2026 | Viewed by 56 | Submission Open

Keywords: stroke prevention; acute stroke management; post-acute stroke care; predictive modeling; risk stratification; neuroimaging; biomarkers; early detection; prognostic evaluation; diagnostic algorithms; cerebral infarction; intracranial hemorrhage; ischemic stroke subtypes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Application of Large Language Models (LLMs) and Vision-Language Models (VLMs) in Healthcare

edited by

Shuo-Chen Chien

and

Wen-Shan Jian

submission deadline 31 May 2026 | Viewed by 46 | Submission Open

Keywords: large language models (LLMs); vision-language models (VLMs); artificial intelligence in healthcare; natural language processing (NLP); clinical decision support systems; medical imaging analysis; multimodal learning; healthcare data analytics; patient-centered care; ethical AI in medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Asthma

edited by

Padukudru Anand Mahesh

submission deadline 31 May 2026 | Viewed by 45 | Submission Open

Keywords: asthma; diagnosis; management; biomarkers; biologics; phenotypes; endotypes; precision medicine; digital health; autoimmune; cytokine; interleukin

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Latest Advances in Ophthalmic Imaging: Second Edition

edited by

Slawomir Teper

and

Gawęcki Maciej

submission deadline 31 May 2026 | Viewed by 36 | Submission Open

Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

From Data to Decisions: Deep Learning in Clinical Diagnostics

edited by Jianfu Li

submission deadline 31 May 2026 | Viewed by 31 | Submission Open

Keywords: deep learning; clinical diagnostics; medical AI; diagnostic accuracy; clinical decision support; medical imaging; biomarker discovery; healthcare implementation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Options and Treatment Strategies for Neurological Disorders

edited by

Julia Koehn

submission deadline 31 May 2026 | Viewed by 25 | Submission Open

Keywords: neuroscience; diagnostic tools; point-of-care testing; prehospital care; emergency medicine; rapid and accurate diagnosis; treatment strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Inflammation and Infection Imaging: 2nd Edition

edited by

Giorgio Treglia

submission deadline 31 May 2026 | Viewed by 24 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Urological Diagnostics: Emerging Technologies and Innovative Approaches

edited by

José Enrique Robles-García

submission deadline 31 May 2026 | Viewed by 19 | Submission Open

Keywords: urological diseases; diagnostic imaging; biomarkers; molecular diagnostics; prostate cancer diagnosis; renal disease diagnosis; artificial intelligence in urology; noninvasive diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging in Ocular Surface

edited by

Nir Erdinest

and David Berkow

submission deadline 31 May 2026 | Viewed by 18 | Submission Open

Keywords: ocular surface imaging; contact lens fitting; ultra-high-resolution oct; corneal topography; corneal tomography; scleral profilometry; wavefront aberrometry; in vivo confocal microscopy; artificial intelligence in eye imaging; meibomian gland imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Precise Diagnosis, Classification, and Monitoring of Pulmonary Diseases

edited by

Barbara Ruaro

Paola Confalonieri

and

Francesco Salton

submission deadline 31 May 2026 | Viewed by 16 | Submission Open

Keywords: lung diseases; pulmonary diseases; imaging techniques; causal biological pathways; clinical biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 May 2026 | Viewed by 15 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Trends and Novelties in Bone Imaging

edited by Kamyar Moradi

submission deadline 31 May 2026 | Viewed by 14 | Submission Open

Keywords: artificial intelligence; biomarkers; bone imaging; bone aging; osteoporosis; osteoarthritis; quantitative imaging; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Data Science and Artificial Intelligence in Laboratory Medicine

edited by

Fernando Marques-Garcia

submission deadline 1 Jun 2026 | Viewed by 101 | Submission Open

Keywords: artificial intelligence; data science; algorithm; laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Insights into the Diagnosis of Gynecological Diseases

edited by

Dah Ching Ding

submission deadline 30 Jun 2026 | 5 articles | Viewed by 18467 | Submission Open

Keywords: gynecological diseases; precision medicine; molecular diagnostics; artificial intelligence; biomarkers; next-generation sequencing; imaging technologies; big data

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

3rd Edition: AI/ML-Based Medical Image Processing and Analysis

edited by

Ghazanfar Latif

and

Jaafar Alghazo

submission deadline 30 Jun 2026 | 6 articles | Viewed by 7539 | Submission Open

Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Clinical Decision Support—2nd Edition

edited by

Qingqing Mao

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6651 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support; predictive modeling; patient monitoring; diagnostic support; treatment recommendation; safety and privacy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 30 Jun 2026 | 5 articles | Viewed by 6269 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Imaging for Radiation Oncology

edited by

Sara Haseli

and Arash Azhideh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 6246 | Submission Open

Keywords: radiation oncology; diagnostic imaging; artificial intelligence; radiomics; tumor detection; molecular imaging; treatment planning; radiogenomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy

edited by

Caterina Carollo

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2112 | Submission Open

Keywords: kidney; nephrology; ultrasounds; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Displaying special issue 501-550 on page 11 of 14.

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