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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Exploring the Genetic and Epigenetic Factors in Leukemia and Lymphoma (2nd Edition)

edited by

Francesco E. Boccalatte

submission deadline 31 Oct 2026 | Viewed by 67 | Submission Open

Keywords: hematology; leukemia; lymphoma; epigenetics; bioinformatics; gene expression; chromatin conformation

(This special issue belongs to the Section Cancer Therapy)

Opportunities and Challenges in Cancer Immunotherapies

edited by

Gao Zhang

submission deadline 31 Oct 2026 | Viewed by 65 | Submission Open

Keywords: cancer immunotherapy; immune checkpoint inhibitors; cellular therapy; tumor microenvironment; therapeutic resistance

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

AI-Driven Advanced Radiotherapy: Towards Personalized, Predictive, and Adaptive Cancer Treatment

edited by Zhen Tian and Chaoqiong Ma

submission deadline 31 Oct 2026 | Viewed by 64 | Submission Open

Keywords: radiotherapy; artificial intelligence; machine learning; deep learning; outcome prediction; treatment planning; adaptive RT; personalized RT; radiomics

(This special issue belongs to the Section Methods and Technologies Development)

Oxidative Stress in Cancer: From Mechanisms to Therapeutic Strategies

edited by

Francesco Marotta

and

Reza Rastmanesh

submission deadline 31 Oct 2026 | Viewed by 57 | Submission Open

Keywords: redox signaling; tumor microenvironment; senolytics; immunometabolism; gut microbiome; preventive oncology; drug delivery

(This special issue belongs to the Section Cancer Therapy)

Local, Systemic and Combined Therapy for Hepatocellular Carcinoma

edited by Xiaoqun Dong

submission deadline 31 Oct 2026 | Viewed by 52 | Submission Open

Keywords: hepatocellular carcinoma; immunotherapy; cell therapy; targeted therapy; local therapy; combination therapy; oncolytic virus; precision oncology; drug resistance; translational research

(This special issue belongs to the Section Cancer Therapy)

Pituitary Tumors: Molecular Insights, Diagnosis, and Targeted Therapy—Third Edition

edited by

Kazunori Kageyama

and

Mitsuru Nishiyama

submission deadline 31 Oct 2026 | Viewed by 52 | Submission Open

Keywords: acromegaly; adrenocorticotropic hormone; Cushing’ s disease; diagnosis; growth hormone; pituitary tumor; proliferation; transcriptional factor; treatment

Innovations in Surgical and Management Strategies for Complex and Advanced Gastric Cancer

edited by

Tsutomu Namikawa

and

Kazuhiro Hanazaki

submission deadline 31 Oct 2026 | Viewed by 47 | Submission Open

Keywords: advanced gastric cancer; surgical innovation; multimodal therapy; minimally invasive gastrectomy (robotic/laparoscopic); perioperative management; immunotherapy; precision medicine; peritoneal metastasis

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Imaging Techniques of Molecular Oncology (2nd Edition)

edited by

Angela Spanu

submission deadline 31 Oct 2026 | Viewed by 42 | Submission Open

Keywords: cancer; oncological imaging; molecular imaging; SPECT/TC; PET/CT; PET/MRI; DWI; DCE-MRI; nanotheranostics; artificial intelligence; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Skin and Hair Side Effects of Cancer Treatment

edited by Ian W. Tattersall

submission deadline 31 Oct 2026 | Viewed by 37 | Submission Open

Keywords: oncodermatology; toxicity management; supportive oncology

(This special issue belongs to the Section Cancer Therapy)

Genetic Disorders and Cancer Susceptibility: Molecular Mechanisms, Risk Assessment, and Targeted Therapies

edited by Silmara de Lima

submission deadline 31 Oct 2026 | Viewed by 10 | Submission Open

Keywords: neurofibromatosis type-1; optic pathway glioma; retinal ganglion cell survival; myelination; vision loss; targeted therapies

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Insights into Glioma Immunotherapy

edited by Tomasz Tykocki

submission deadline 5 Nov 2026 | Viewed by 19 | Submission Open

Keywords: glioma immunotherapy; tumor microenvironment; immune evasion; microglia; checkpoint inhibitors; CAR‑T; neoantigen vaccines

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Evaluating the Clinical Impact of Robotic Surgery in the Management of Colorectal Cancer

edited by

Héctor Guadalajara

and Miguel Leon-Arellano

submission deadline 15 Nov 2026 | Viewed by 117 | Submission Open

Keywords: robotic surgery; colorectal cancer; oncological outcomes; surgical technique; laparoscopic comparison; margin status; postoperative recovery; quality of life; intraoperative imaging; surgical navigation; learning curve; complications; cost-effectiveness; surgical training; technological innovation

(This special issue belongs to the Section Clinical Research of Cancer)

Recent Advances in Endoscopic, Metabolomic, and Ultrasound Approaches to Gastrointestinal, Hepatic, and Pancreatic Tumors

edited by Ciprian Brisc and Nadim Al Hajjar

submission deadline 15 Nov 2026 | Viewed by 36 | Submission Open

Keywords: gastrointestinal; hepatic and pancreatic tumors; metabolomics; endoscopy; ultrasound; elastography; molecular investigations and treatment; robotic surgery; laparoscopic surgery; early lesions; radiofrequency and microwave ablation; irreversible electroporation; cryoablation; targeted chemo- or radio-embolization

(This special issue belongs to the Section Cancer Therapy)

The Pathologic Diagnosis and Clinical Therapy of Neuroendocrine Tumors: 2nd Edition

edited by

Salvatore Tafuto

Ottavia Clemente

and

Annabella Di Mauro

submission deadline 20 Nov 2026 | Viewed by 46 | Submission Open

Keywords: neuroendocrine neoplasms; molecular mechanisms; cancer pathogenesis; tumorigenesis; diagnosis; molecular and cellular heterogeneity; predictive biomarkers; animal models and of neuroendocrine cancer; diagnostic clinical oncology; genomic characterization; clinical biomarkers; biomarkers of drug response; epigenetic biomarkers; targeted therapy; tumor immunity; molecular oncology; clinical therapy

Cancer Cells Fostered Microenvironment in Metastasis (2nd Edition)

edited by

Lin Ye

submission deadline 25 Nov 2026 | Viewed by 31 | Submission Open

Keywords: cancer cells; tumour microenvironment; metastasis; fibroblast; immune cells; extracellular ma-trix; adhesion; migration; invasion; drug resistance; target therapy

(This special issue belongs to the Section Cancer Metastasis)

Radiologic Staging and Surgical Decision-Making in the Era of Neoadjuvant Therapy for Breast Cancer

edited by

Damiano Gentile

submission deadline 25 Nov 2026 | Viewed by 27 | Submission Open

Keywords: radiologic staging; neoadjuvant therapy; breast cancer; breast-conserving surgery; mastectomy; targeted axillary dissection; sentinel lymph node biopsy; axillary lymph node dissection; magnetic resonance imaging; surgical de-escalation

(This special issue belongs to the Section Cancer Therapy)

Treatment and Prognosis of Pediatric Medulloblastoma

edited by Marwa Ismail

submission deadline 25 Nov 2026 | Viewed by 26 | Submission Open

Keywords: pediatric medulloblastoma; proteomics; radiogenomics

(This special issue belongs to the Section Pediatric Oncology)

Infectious Pathogens and Cancer

edited by

W. Martin Kast

submission deadline 25 Nov 2026 | Viewed by 23 | Submission Open

Keywords: infectious cancer pathogens; related topics in immunology; virology; epidemiology; (therapeutic) vaccines; oncogenesis; screening; therapy

(This special issue belongs to the Section Infectious Agents and Cancer)

New Findings in Targeting Cancer Proteins (Second Edition)

edited by

Maristella Maggi

and

Claudia Scotti

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2699 | Submission Open

Keywords: monoclonal antibodies; protein target; immunotherapy; signaling blockade; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Artificial Intelligence and Machine Learning in Lung Cancer

edited by

Jianjun Zhang

Jia Wu

and

Morteza Salehjahromi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1205 | Submission Open

Keywords: artificial intelligence; machine learning; lung cancer screening; low-dose CT; early detection

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

In Vitro and In Vivo Pharmacology for Glioma Drug Discovery

edited by

Anna Bielecka-Wajdman

submission deadline 30 Nov 2026 | 1 articles | Viewed by 462 | Submission Open

Keywords: pre-clinical modern in vitro /in vivo glioma models; complementary glioma therapy; immunotherapy in glioma; inhibition of glioma recurrence

(This special issue belongs to the Section Cancer Drug Development)

Advances in Nanoparticle and Exosome Technology for Delivery of Payloads in CNS Tumors

edited by

Ali S. Arbab

submission deadline 30 Nov 2026 | Viewed by 147 | Submission Open

Keywords: glioblastoma; brain metastasis; nanoparticles; exosomes; viral therapy; delivery of payload; imaging probes

(This special issue belongs to the Section Cancer Drug Development)

New Approaches to Surgical Treatment and Care for Urological Cancer

edited by

Susanne Vahr Lauridsen

and Bente Thoft Jensen

submission deadline 30 Nov 2026 | Viewed by 115 | Submission Open

Keywords: bladder cancer; prostate cancer; kidney cancer; penile cancer; patient perspective; patient education; enhanced recovery after surgery (ERAS) protocols; prehabilitation rehabilitation; sexual health

(This special issue belongs to the Section Clinical Research of Cancer)

New Clinical Insights into Gastrointestinal Cancers

edited by Dai Shida

submission deadline 30 Nov 2026 | Viewed by 88 | Submission Open

(This special issue belongs to the Section Clinical Research of Cancer)

After Cancer Remission: Tracking Minimal Residual Disease and Relapse

edited by

Andriani Charpidou

Ioannis P. Trontzas

and

Emmanouil Panagiotou

submission deadline 30 Nov 2026 | Viewed by 76 | Submission Open

Keywords: minimal residual disease (MRD); cancer relapse; liquid biopsy; circulating tumor DNA (ctDNA); biomarkers; molecular monitoring; post-remission surveillance; translational oncology; multi-omics; personalized cancer care; precision medicine

Advances in the Management of Pelvic Tumors: 2nd Edition

edited by Giorgia Gaia and

Maria Chiara Sighinolfi

submission deadline 30 Nov 2026 | Viewed by 62 | Submission Open

Keywords: pelvic cancer; prostate cancer; bladder cancer; uterine cancer; ovarian cancer; rectal cancer; anal cancer

(This special issue belongs to the Section Cancer Therapy)

Acute Myeloid Leukemia: Novel Therapeutic Agents and Clinical Trials

edited by Wieslaw W. Jedrzejczak

submission deadline 30 Nov 2026 | Viewed by 61 | Submission Open

Keywords: acute leukemia; targeted therapy; antibody– drug conjugates

(This special issue belongs to the Section Clinical Research of Cancer)

Intraoperative Radiotherapy in Cancer Treatment

edited by

Falk Roeder

submission deadline 30 Nov 2026 | Viewed by 40 | Submission Open

Keywords: intraoperative radiation therapy; image-guided IORT; IOERT; kV-IORT; HDR-IORT; FLASH

(This special issue belongs to the Section Cancer Therapy)

Advances in Adoptive Cell Therapy for Cancer

edited by Andrew Furness

submission deadline 30 Nov 2026 | Viewed by 17 | Submission Open

Keywords: CAR-T cells; adoptive cell therapy; tumor microenvironment; immunotherapy; translational oncology

Clinical Treatment and Prognostic Factors of Urologic Cancer

edited by

Hiroaki Iwamoto

submission deadline 15 Dec 2026 | 13 articles | Viewed by 38483 | Submission Open

Keywords: prostate cancer; bladder cancer; urothelial carcinoma; upper urinary tract tumors; kidney cancer; renal cell carcinoma; testicular tumors; molecular markers; diagnosis; systemic treatment

(This special issue belongs to the Section Cancer Therapy)

The Evolving Landscape of Squamous Cell Carcinoma of the Anal Canal: State of the Art, Current Challenges and Future Perspectives

edited by

Alessandra Boccaccino

and Francesco Vasuri

submission deadline 15 Dec 2026 | Viewed by 67 | Submission Open

Keywords: squamous cell anal carcinoma; anal cancer; HIV; HPV

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (2nd Edition)

edited by

Armita Bahrami

and

Ying Qing

submission deadline 20 Dec 2026 | 1 articles | Viewed by 496 | Submission Open

Keywords: cancer genetics; cancer epigenetics; carcinogenesis; cancer prognosis; cancer therapeutics; genetic mutations; DNA methylation; histone modifications; RNA methylation

(This special issue belongs to the Section Molecular Cancer Biology)

Hematological Malignancies: From Translational Discoveries to Clinical Trends

edited by

Arati Sharma

and Charyguly Annageldiyev

submission deadline 20 Dec 2026 | Viewed by 85 | Submission Open

Keywords: hematological malignancies; leukemia; lymphoma; myeloma; translational research; preclinical studies; clinical outcomes; molecular biomarkers; targeted therapy; precision medicine

(This special issue belongs to the Section Cancer Therapy)

The State of the Art in Cardio-Oncology

edited by

Fabio Maria Turazza

submission deadline 20 Dec 2026 | Viewed by 66 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; cancer therapeutics; reverse cardio-oncology; precision cardio-oncology; genetics in cardio-oncology

Retroviruses and Cancer Development: Molecular Mechanisms and Therapeutic Prospects

edited by Donna D'Agostino and

Vincenzo Ciminale

submission deadline 20 Dec 2026 | Viewed by 18 | Submission Open

Keywords: retroviruses; cancer; ERV; antivirals; persistent infection

(This special issue belongs to the Section Infectious Agents and Cancer)

Cancer Cell Death and Immune Response

edited by Seema Singh and

Amod Sharma

submission deadline 25 Dec 2026 | Viewed by 45 | Submission Open

Keywords: immunogenic cell death; tumor immunity; epigenetics; apoptosis; tumor microenvironment; biomarkers

(This special issue belongs to the Section Molecular Cancer Biology)

Tumor–Microbiota Crosstalk: Immune Modulation and Resistance to Cancer Therapies

edited by

Massimiliano Berretta

submission deadline 25 Dec 2026 | Viewed by 38 | Submission Open

Keywords: tumor– microbiota; immune modulation; cancer therapies

(This special issue belongs to the Section Infectious Agents and Cancer)

Immunotherapy with Checkpoint Inhibitors for Non-Small-Cell Lung Cancer (2nd Edition)

edited by

Alessandro Inno

and

Diego Signorelli

submission deadline 30 Dec 2026 | Viewed by 146 | Submission Open

Keywords: immune-checkpoint inhibitors; non-small cell lung cancer; neoadjuvant therapy; adjuvant therapy; primary resistance; acquired; resistance; biomarkers; immune-related adverse events

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Nanomedicine’s Role in Oncology

edited by

Efstathios Efstathopoulos

and

Ellas Spyratou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2307 | Submission Open

Keywords: nanomedicine; oncology; interventional oncology; nanotechnology development; cancer diagnosis; cancer treatment; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Multiple Myeloma—Biology, Diagnosis, Treatment and Prognosis (2nd Edition)

edited by

Cirino Botta

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2246 | Submission Open

Keywords: multiple myeloma; bone marrow microenvironment; minimal residual disease; mass spectrometry; flow cytometry; CAR-T; bispecific agents; genomic alterations

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Cancer Survival Analysis

edited by

Tianhui (Thomas) Chen

, Jianguang Ji and

Jun Lyu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 955 | Submission Open

Keywords: cancer burden; cancer survival; epidemiology; survival analysis methodology; cancer screening; cancer control; cancer prognosis; cancer data mining

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

CancersScape: Spatial Biology of the Tumor Ecosystem

edited by

Samuel C. Mok

and Sammy Ferri-Borgogno

submission deadline 31 Dec 2026 | Viewed by 823 | Submission Open

Keywords: cancer; health; tumor microenvironment; spatial biology; cancer diagnosis; cancer drug discovery; Omics

Cancer Patient Cognitive Disorders: Causes, Prevention and Management

edited by

Jeffrey Jianhong Huang

submission deadline 31 Dec 2026 | Viewed by 412 | Submission Open

Keywords: delirium; brain health; cognitive impairment; cancer; etiology; risk stratification; screening tool; biomarkers; postoperative delirium; pain management; delirium prevention; management; outcomes

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle

edited by

Hiroaki Kiyokawa

submission deadline 31 Dec 2026 | Viewed by 325 | Submission Open

Keywords: cell cycle; signaling pathway; precision medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer Cell Communications, Metastasis and Survival in the Host Microenvironment—2nd Edition

edited by

Nan-Shan Chang

and

Yanping Liu

submission deadline 31 Dec 2026 | Viewed by 186 | Submission Open

Keywords: cancer cells; cancer cell-derived cytokines; host microenvironment; metastasis; gene alteration; signaling pathways; host cells

(This special issue belongs to the Section Tumor Microenvironment)

Tumor Microenvironment: Cellular Dynamics, Molecular Players, and Mechanisms of Therapy Resistance

edited by

Teresa Gagliano

, Angeliki Ditsiou and

Viviana Vella

submission deadline 31 Dec 2026 | Viewed by 175 | Submission Open

Keywords: tumor microenvironment (TME); cellular interactions; molecular mechanisms; resistance mechanisms; signaling pathways; translational cancer therapy

(This special issue belongs to the Section Tumor Microenvironment)

Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology

edited by

Meena Kanduri

submission deadline 31 Dec 2026 | Viewed by 124 | Submission Open

Keywords: tumor suppressor genes; oncogenes; cancer; genome analysis; cancer mutations; DNA methylation; histone modification; cancer progression; oncogenesis

(This special issue belongs to the Section Molecular Cancer Biology)

Cutaneous Lymphomas: Present and Future

edited by

Alessandro Pileri

submission deadline 31 Dec 2026 | Viewed by 114 | Submission Open

Keywords: cutaneous lymphoma; T-cell lymphoma; B-cell lymphoma; mycosis fungoides; Sé zary syndrome; tumor microenvironment

Laparoscopic and Robotic Surgery for Gastrointestinal and Hepato-Pancreato-Biliary Cancers

edited by

Kosei Takagi

submission deadline 31 Dec 2026 | Viewed by 73 | Submission Open

Keywords: minimally invasive surgery; laparoscopic surgery; robotic surgery; gastrointestinal cancers; hepato-pancreato-biliary cancers; neoadjuvant therapy; adjuvant therapy; outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Pathogenesis and Treatment Strategies in Multiple Myeloma: From Basic Research to Real Life: 2nd Edition

edited by Shingen Nakamura

submission deadline 31 Dec 2026 | Viewed by 66 | Submission Open

Keywords: myeloma bone disease; denosumab; bisphosphonate; infectious complication; proteasome inhibitor; IMiDs; anti-CD38 antibody; venetoclax; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 1151-1200 on page 24 of 25.

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