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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Multidisciplinary Strategies in Challenging Neuro-Oncological Surgery
edited by
submission deadline 20 Aug 2026 | Viewed by 6 | Submission Open
Keywords: neuro-oncology; surgery; awake craniotomy; intraoperative MRI; MRI navigation system; intraoperative photodynamic diagnosis/therapy; intraoperative pathological diagnosis
(This special issue belongs to the Section Clinical Research of Cancer)
Diagnostic Biomarkers in Cancers Study
edited by Zejuan Li and
submission deadline 21 Aug 2026 | 4 articles | Viewed by 6999 | Submission Open
Keywords: cancer; diagnostics; biomarker
(This special issue belongs to the Section Cancer Biomarkers)
Contemporary Diagnosis and Management of Prostate Cancer (2nd Edition)
edited by Thomas Jang
submission deadline 22 Aug 2026 | 1 articles | Viewed by 1422 | Submission Open
Keywords: prostate cancer; diagnosis; management; radical prostatectomy; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Study on Clinical Studies of Colorectal Cancer Surgery
edited by and Ioannis Baloyiannis
submission deadline 25 Aug 2026 | Viewed by 38 | Submission Open
Keywords: colon; rectal; cancer; clinical; trials; evidence; open; laparoscopic; robotic; surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Modern Approach to Oral Cancer submission deadline 30 Aug 2026 | 11 articles | Viewed by 47765 | Submission Open
Keywords: oral cancer; neoplasm; oral surgery oncogenesis; dentistry oral health
(This special issue belongs to the Section Cancer Therapy)
Pathology of Acute Myeloid Leukemia (AML)
edited by Olga K. Weinberg
submission deadline 30 Aug 2026 | Viewed by 1263 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Long-Term Health Outcomes and Quality of Life in Survivors of Childhood Cancer submission deadline 30 Aug 2026 | 2 articles | Viewed by 942 | Submission Open
Keywords: acute lymphoblastic leukemia; brain tumors; childhood cancer survivors; pollutants; environment; quality of life; nutrition; chemotherapy; air and water purification
(This special issue belongs to the Section Pediatric Oncology)
Pathology of Gynecological Cancers (2nd Edition)
edited by
submission deadline 30 Aug 2026 | Viewed by 262 | Submission Open
Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervical cancer; vaginal cancer
(This special issue belongs to the Section Cancer Pathophysiology)
Proteometabolomics in Cancer submission deadline 30 Aug 2026 | Viewed by 147 | Submission Open
Keywords: proteomics; metabolomics; cancer biology; tumor microenvironment; biomarkers; therapeutics
(This special issue belongs to the Section Molecular Cancer Biology)
Robotic and Laparoscopic Surgery in Colorectal Cancer: Current Trends and Future Perspectives
edited by , Quentin Denost and Barbara Noiret
submission deadline 30 Aug 2026 | Viewed by 138 | Submission Open
Keywords: robotic surgery; laparoscopic surgery; colorectal cancer; minimally invasive surgery; comparative outcomes (perioperative; oncologic; functional); conversion rates; open surgery; learning curve and surgical training; cost‐effectiveness and health economics; technological innovations (e.g.; AI; imaging; instrumentation); quality of life and long‐term patient‐reported outcomes
(This special issue belongs to the Section Cancer Therapy)
Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)
edited by , and I-Cheng Lee
submission deadline 30 Aug 2026 | Viewed by 97 | Submission Open
Keywords: tumor suppressor; targeted therapy; hepatocellular carcinoma
(This special issue belongs to the Section Tumor Microenvironment)
Neoantigen Vaccines for Cancer Therapy
edited by Takashi Morisaki
submission deadline 30 Aug 2026 | Viewed by 93 | Submission Open
Keywords: neoantigens; vaccine; dendritic cells; cancer; immunotherapy; priming; CTL; helper T cells
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Gastrointestinal Malignancy: Epidemiology and Risk Factors
edited by Patrick Okolo and Chengu Niu
submission deadline 31 Aug 2026 | 8 articles | Viewed by 33463 | Submission Open
Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes
edited by Petros I. Bangeas and Vasileios N. Papadopoulos
submission deadline 31 Aug 2026 | 4 articles | Viewed by 17818 | Submission Open
Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
Advancements in “Cancer Biomarkers” for 2025–2026 submission deadline 31 Aug 2026 | 11 articles | Viewed by 17485 | Submission Open
Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis
(This special issue belongs to the Section Cancer Biomarkers)
Feature Review Paper Special Issue in Section Molecular Cancer Biology
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 9478 | Submission Open
Keywords: molecular biology; cell biology; cancer; tumor; cancer cell
(This special issue belongs to the Section Molecular Cancer Biology)
Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer
edited by and
submission deadline 31 Aug 2026 | 4 articles | Viewed by 5586 | Submission Open
Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis submission deadline 31 Aug 2026 | 3 articles | Viewed by 4618 | Submission Open
Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance
(This special issue belongs to the Section Molecular Cancer Biology)
The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition
edited by and Frullanti Elisa
submission deadline 31 Aug 2026 | 1 articles | Viewed by 3825 | Submission Open
Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics
(This special issue belongs to the Section Cancer Therapy)
CAR T-Cell Therapy and Multiple Myeloma
edited by Jo Caers
submission deadline 31 Aug 2026 | 1 articles | Viewed by 914 | Submission Open
Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Tumor Microenvironment in Cancer Therapies: Supportive or Hostile? submission deadline 31 Aug 2026 | 1 articles | Viewed by 735 | Submission Open
Keywords: tumor microenvironment; protumor effects; antitumor effects; immune cells; stromal cells; extracellular matrix; cancer therapies
(This special issue belongs to the Section Tumor Microenvironment)
New Advances and Approaches in Thyroid Cancer
edited by and José Manuel Rodríguez
submission deadline 31 Aug 2026 | 1 articles | Viewed by 718 | Submission Open
Keywords: thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; poorly differentiated thyroid tumours; novel approaches; prognostic biomarkers; risk stratification
(This special issue belongs to the Section Cancer Therapy)
Emergencies in Gastrointestinal Surgical Oncology submission deadline 31 Aug 2026 | Viewed by 569 | Submission Open
Keywords: surgical oncology; emergencies; emergency surgery; acute care surgery; palliation; futility in surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Hereditary Cancer: State of the Art
edited by Joanne Ngeow, Jianbang Chiang and
submission deadline 31 Aug 2026 | Viewed by 210 | Submission Open
Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance
(This special issue belongs to the Section Cancer Pathophysiology)
Hypoxia-Targeting Strategies to Improve Cancer Therapy Outcomes
edited by Roben Gieling and Ayse Latif
submission deadline 31 Aug 2026 | Viewed by 151 | Submission Open
Keywords: tumor hypoxia; cancer therapy resistance; hypoxia-targeted therapy; hypoxia-inducible factors (HIFs); hypoxia-activated prodrugs; oxygen-modifying agents; combination therapy; precision drug delivery; tumor microenvironment; translational cancer research
(This special issue belongs to the Section Cancer Therapy)
CAR T Cell Therapy in Cancer: Progress and Challenges Across Solid and Hematologic Malignancies
edited by John F. Marshall and Lauren C. Cutmore
submission deadline 31 Aug 2026 | Viewed by 117 | Submission Open
Keywords: CAR-T cell therapy; adoptive cell therapy; immunotherapy; antigen escape; solid tumor; hematologic malignancies
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Acute Myeloid Leukemia in Adults (2nd Edition) submission deadline 31 Aug 2026 | Viewed by 109 | Submission Open
Keywords: acute myeloid leukemia; molecular biology; treatment landscape; resistance mechanisms
(This special issue belongs to the Section Clinical Research of Cancer)
Clinical Treatment and Outcomes of Gastrointestinal Cancer
edited by Mary Linton Peters
submission deadline 31 Aug 2026 | Viewed by 104 | Submission Open
Keywords: gastrointestinal cancer; ctDNA; chemotherapy; immunotherapy; financial toxicity; clinical trial participation
(This special issue belongs to the Section Clinical Research of Cancer)
Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact
edited by Jun-Pyo Myong
submission deadline 31 Aug 2026 | Viewed by 102 | Submission Open
Keywords: occupational exposure; chemical carcinogens; risk assessment; epidemiology; biomarkers; exposure assessment; preventive strategies; workplace safety; occupational health; regulatory measures
(This special issue belongs to the Section Infectious Agents and Cancer)
The Unseen Burden: Incidence and Outcomes of Infections in Leukemia submission deadline 31 Aug 2026 | Viewed by 93 | Submission Open
Keywords: infection management; infectious risk; antimicrobial therapy; antimicrobial prophylaxis
(This special issue belongs to the Section Infectious Agents and Cancer)
Advances in the Early Diagnosis and Treatment of Gastric Cancer (2nd Edition)
edited by Sharona B. Ross
submission deadline 31 Aug 2026 | Viewed by 83 | Submission Open
Keywords: gastric cancer; tumor resection; liver tumors
(This special issue belongs to the Section Cancer Therapy)
Advances in the Multimodal Management of Pancreatic Ductal Adenocarcinoma submission deadline 31 Aug 2026 | Viewed by 78 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); multimodal approach; systemic therapy; radiotherapy; targeted strategies; neoadjuvant therapy; adjuvant therapy
(This special issue belongs to the Section Cancer Therapy)
Early Detection and Strategies for Overcoming Therapy Resistance in Lung Cancer and Mesothelioma
edited by
submission deadline 31 Aug 2026 | Viewed by 75 | Submission Open
Keywords: lung cancer; mesothelioma; screening; biomarker; molecular diagnostics; resistance
(This special issue belongs to the Section Cancer Therapy)
Wnt Signaling Pathway in Cancer Immunotherapy
edited by and
submission deadline 31 Aug 2026 | Viewed by 61 | Submission Open
Keywords: Wnt signaling; immunotherapy; immune cells; macrophages; T-cell; CART cells; stromal cells; tumor microenvireonment; cancers; cancer stem cells
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
mTOR Signaling in Cancer
edited by
submission deadline 31 Aug 2026 | Viewed by 22 | Submission Open
Keywords: mTOR; cancer; cell signaling; pathway addiction; tumor metabolism; glycolysis; autophagy; apoptosis; rapamycin
(This special issue belongs to the Section Molecular Cancer Biology)
Cytoskeleton in Tumor Growth and Progression
edited by David Gau
submission deadline 31 Aug 2026 | Viewed by 19 | Submission Open
Keywords: actin cytoskeleton; microtubules; mechano-transduction; tumor microenvironment; angiogenesis; mitochondria
(This special issue belongs to the Section Molecular Cancer Biology)
Advancements in Brain Cancer Research: From Molecular Mechanisms to Translational Therapeutic Strategies submission deadline 31 Aug 2026 | Viewed by 9 | Submission Open
Keywords: brain cancer; glioblastoma; tumor microenvironment; cancer stem cells; molecular therapeutics; epigenetic regulation; nanomedicine; translational oncology; therapeutic resistance
Applications of Computed Tomography in Lung Cancer
edited by Yukinori Sakao
submission deadline 31 Aug 2026 | Viewed by 3 | Submission Open
Keywords: lung cancer; computed tomography (CT); radiomics; artificial intelligence (AI); image-guided surgery
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Trials for T-Cell Lymphoma
edited by Jasmine Zain
submission deadline 31 Aug 2026 | Viewed by 1 | Submission Open
Keywords: peripheral T cell lymphoma; EZH2 inhibitors; JAK STAT  pathways; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Clinical Research of Cancer)
The Role of Artificial Intelligence in Detection and Treatment of Head and Neck Cancer
edited by
submission deadline 31 Aug 2026 | Viewed by 1 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; large language models; multimodal integration; computer vision; pathomics; image-derived biomarkers
(This special issue belongs to the Section Methods and Technologies Development)
Discovery and Development of New Anticancer Drugs and Delivery Systems: Special Emphasis on Artificial Intelligence, Machine-Learning, and Big Data Analysis submission deadline 31 Aug 2026 | Submission Open
Keywords: artificial intelligence; machine learning; big-data analytics; natural compounds; translational oncology; drug delivery systems
(This special issue belongs to the Section Cancer Drug Development)
Cancer Therapy-Related Adverse Events (2nd Edition)
edited by and Pauline Funchain
submission deadline 1 Sep 2026 | 2 articles | Viewed by 5706 | Submission Open
Keywords: cancer; cancer therapy; toxicities; adverse events
(This special issue belongs to the Section Cancer Therapy)
The Role of Minimally Invasive and Minimally Radical Surgery in Cervical and Endometrial Cancer
edited by , , Christophe Pomel, and Gwénaël Ferron
submission deadline 1 Sep 2026 | 1 articles | Viewed by 289 | Submission Open
Keywords: cervical cancer; endometrial cancer; laparoscopic surgery; minimally invasive surgery; surgical oncology; fertility-sparing surgery; non-radical surgery; conservative surgery
(This special issue belongs to the Section Cancer Therapy)
Prostatectomy Today: Surgical Advances in Prostate Cancer Management
edited by
submission deadline 1 Sep 2026 | Viewed by 80 | Submission Open
Keywords: prostate cancer; robot-assisted radical prostatectomy; robotic system; perioperative outcomes; sexual function; urinary continence; oncological outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology
edited by and Geovana Leite
submission deadline 10 Sep 2026 | 1 articles | Viewed by 1240 | Submission Open
Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
Advances in Interventional Oncologic Therapies
edited by Edward W. Lee and
submission deadline 15 Sep 2026 | 3 articles | Viewed by 11184 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
First-Line Therapy in Thoracic Oncology
edited by Antonio D'Andrilli and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 3986 | Submission Open
Keywords: thoracic oncology; lung cancer; thymoma; mediastinal tumors
(This special issue belongs to the Section Cancer Therapy)
The Clinical, Technological, and Scientific Progress of Boron Neutron Capture Therapy
edited by
submission deadline 15 Sep 2026 | Viewed by 760 | Submission Open
Keywords: boron neutron capture therapy (BNCT); neutron capture therapy (NCT); accelerator-based neutron source; neutron dosimetry; boron drug development; alternative capture agents; radiobiological effects; radiation oncology; interdisciplinary research; clinical translation
(This special issue belongs to the Section Cancer Therapy)
Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer submission deadline 15 Sep 2026 | Viewed by 105 | Submission Open
Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes
edited by
submission deadline 15 Sep 2026 | Viewed by 103 | Submission Open
Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care
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