Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Diagnosis, Treatment, and Prognosis of Uveal Melanoma
edited by Josep Maria Caminal Mitjana
submission deadline 30 Jun 2025 | 5 articles | Viewed by 7225 | Submission Open
Keywords: uveal melanoma; choroidal melanoma; gene expression profiling; immunotherapy; metastasis; radiotherapy; liquid biopsy; circulating tumor cells; brachytherapy; next-generation sequencing; proton therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Cutaneous Lymphomas: From Pathology to Treatment
edited by Weiyun Z. Ai and
submission deadline 30 Jun 2025 | 5 articles | Viewed by 7099 | Submission Open
Keywords: cutaneous T cell lymphoma; mycosis fungoides and Sezary syndrome; pathogenesis/biomarker discovery; tumor microenvironment; pre-clinical and clinical studies; biological insights
(This special issue belongs to the Section Cancer Therapy)
Technical Advances in Esophageal Cancer Treatment submission deadline 30 Jun 2025 | 5 articles | Viewed by 6678 | Submission Open
Keywords: artificial intelligence; predicting response; fluorescence; indocyanine green; SQA
(This special issue belongs to the Section Methods and Technologies Development)
Intraoperative Visualization Techniques and Advanced Imaging in Brain Tumors submission deadline 30 Jun 2025 | 4 articles | Viewed by 6634 | Submission Open
Keywords: glioma; glioblastoma; brain metastasis; diffusion tensor imaging; fiber tracking; functional MRI; intraoperative fluorescence; intraoperative MRI; intraoperative ultrasound
(This special issue belongs to the Section Methods and Technologies Development)
Application of Biostatistics in Cancer Research
edited by and Han Yu
submission deadline 30 Jun 2025 | 7 articles | Viewed by 5849 | Submission Open
Keywords: clinical trial design; nonparametric statistics; randomization and permutation tests; computational methods in statistics; Bayesian methods; computational biology; graphical models; network analysis; machine learning; artificial intelligence; predictive modeling
(This special issue belongs to the Section Cancer Informatics and Big Data)
Advances in Genetic and Molecular Approaches to Skin Cancer
edited by Egle Ramelyte
submission deadline 30 Jun 2025 | 3 articles | Viewed by 5724 | Submission Open
Keywords: genetic analysis; multi-omics approaches; skin cancer; mutation; epigenetic alteration; proteomics
(This special issue belongs to the Section Molecular Cancer Biology)
Educating Recent Updates on Metastatic Non-small Cell Lung Cancer submission deadline 30 Jun 2025 | 2 articles | Viewed by 5207 | Submission Open
Keywords: non-small cell lung cancer; lung adenocarcinoma; lung squamous cell carcinoma; tumor microenvironment (TME); epithelial to mesenchymal transition (EMT); cancer metastasis; desmoplasia; tumor matrix biology; epigenetic modulations leading cancer metastasis; post-translational modifications (PTMs); immune evasion
(This special issue belongs to the Section Cancer Metastasis)
Regulators of Breast Cancer Metastasis submission deadline 30 Jun 2025 | 2 articles | Viewed by 5052 | Submission Open
Keywords: tumor progression regulators; metastasis; tumor microenvironment; biomarkers for recurrence; transcriptional regulation; chromatin structure; epigenetics; cancer metabolism; cancer immunity; microbiome
(This special issue belongs to the Section Cancer Metastasis)
Gynecologic Oncology: Clinical and Translational Research
edited by , Pasquale Lombardi and Gaia Giannone
submission deadline 30 Jun 2025 | 5 articles | Viewed by 4681 | Submission Open
Keywords: gynecological cancer; ovarian cancer; translational research; effectiveness; toxicity; immunotherapy; PARP inhibitors
(This special issue belongs to the Section Cancer Therapy)
Class 2 Tumor Suppressor Gene Pathways for Therapeutic Applications in Hard-to-Treat Cancers
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 4617 | Submission Open
Keywords: hard-to-treat cancers; HTT cancers; class 2 tumor suppressor genes; C2TSGs; DNA methylation driver; DNAme driver; epigenetic therapies; cancer drug development; personalized cancer therapy; tumor suppressor mimetics
(This special issue belongs to the Section Cancer Therapy)
Advances in Abdominal Surgical Oncology and Intraperitoneal Therapies submission deadline 30 Jun 2025 | 4 articles | Viewed by 4249 | Submission Open
Keywords: abdominal oncologic surgery; minimally invasive techniques; laparoscopy; robotics; fluorescence; artificial intelligence; augmented vision; peritoneal carcinomatosis; intraperitoneal chemotherapy; liquid biopsy
(This special issue belongs to the Section Cancer Therapy)
New Approaches to Hematologic Malignancies Radiation Therapy submission deadline 30 Jun 2025 | 2 articles | Viewed by 4155 | Submission Open
Keywords: hematological neoplasms; radiation therapy; tumor control; imaging modalities; multimodal immune; cell-based therapies; radiation biology; personalized therapy; medical physics; treatment toxicities
(This special issue belongs to the Section Methods and Technologies Development)
Cancer Biomarkers—Detection and Evaluation of Response to Therapy submission deadline 30 Jun 2025 | 4 articles | Viewed by 4128 | Submission Open
Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies
(This special issue belongs to the Section Cancer Biomarkers)
Epigenetic Regulation in Hematologic Malignancies
edited by Travis S. Johnson
submission deadline 30 Jun 2025 | 3 articles | Viewed by 3537 | Submission Open
Keywords: epigenetic regulation; hematologic malignancies; DNA methylation; non-coding RNA; therapeutic targeting
(This special issue belongs to the Section Tumor Microenvironment)
Molecular Mechanisms in Bone and Soft Tissue Sarcomas
edited by and Zachary D.C. Burke
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3486 | Submission Open
Keywords: sarcoma; bone sarcoma; soft tissue sarcoma; osteosarcoma; molecular level; translation
(This special issue belongs to the Section Molecular Cancer Biology)
Cervical Cancer: Clinical Feature, Trial and Management
edited by , and Carlo Saccardi
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3328 | Submission Open
Keywords: cervical cancer; diagnosis; minimally invasive surgery; laparoscopy; locally advanced disease; management; treatment; adjuvant chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Advancements in Image-Guided Radiotherapy for the Treatment of Lung Cancer submission deadline 30 Jun 2025 | 2 articles | Viewed by 3229 | Submission Open
Keywords: lung cancer; functional imaging; stereotactic body radiotherapy; radiomics; biomarkers; artificial intelligence; magnetic resonance imaging
(This special issue belongs to the Section Cancer Therapy)
The Progress of Pancreatectomy for Pancreatic Cancer Treatment submission deadline 30 Jun 2025 | 2 articles | Viewed by 3108 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatectomy timing in multimodal regimen; minimally invasive pancreatectomy for PDAC; pancreatectomy and resectability; extended pancreatectomy; vascular resection and reconstruction; outcome research— pancreatectomy for cancer in unselected patient cohorts; interaction of postoperative complications and preoperative or adjuvant therapy; postoperative pancreatic fistula
(This special issue belongs to the Section Clinical Research of Cancer)
Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs)
edited by Wei Chen, Fei Li and
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2899 | Submission Open
Keywords: MPNs; ET; PV; PMF; post-PV-MF; post-ET-MF; MDS/MPN; JAK2
(This special issue belongs to the Section Molecular Cancer Biology)
New Insights on Management of Acute Lymphoblastic Leukemia in the Contemporary Era
edited by Talha Badar
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2641 | Submission Open
Keywords: B-cell ALL; T-cell ALL; MRD in ALL; Ph+ve ALL; CAR T-cells; NGS-MRD; menin inhibitors; blinatumomab; inotuzumab; ponatinib; BCR-ABL1; TKI
(This special issue belongs to the Section Cancer Therapy)
Imaging of Hepatocellular Carcinomas submission deadline 30 Jun 2025 | 3 articles | Viewed by 2615 | Submission Open
Keywords: computed tomography; magnetic resonance imaging; Gd-EOB-DTPA; PET/CT; LI-RADS; therapeutic response assessment; biomarkers; radiomics; machine learning/deep learning
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Recent Advances in Nanomedicine-Based Cancer Immunotherapy
edited by Navin Kumar Verma, and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2415 | Submission Open
Keywords: cancer nano-therapy; nano-enabled therapeutic; immune checkpoint inhibitors; tumor immunosuppression; adoptive cell therapy; CAR T-cell therapy; tumor-infiltrating lymphocyte therapy; monoclonal antibody therapy for cancer; cancer vaccines; immune system modulators
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Immune-Related Adverse Events in Cancer Immunotherapy
edited by Kate Young and Anna Olsson-Brown
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2370 | Submission Open
Keywords: check point inhibitors (CPIs); immunotherapy; irAEs; immune checkpoint inhibitors (ICIs); survivorship; long-term toxicity; steroid refractory; biologics; CAR-T; TILs
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Local Management of Breast Cancer: The Evolving Relationship Between Radiotherapy and Surgery
edited by Shengyang Peter Wu
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2193 | Submission Open
Keywords: biomarker-guided personalized breast treatment; targeted axillary dissection; neoadjuvant therapy; local therapy; radiotherapy reduction; ultrahypofractionated partial breast irradiation
(This special issue belongs to the Section Cancer Therapy)
Clinical Evaluation of Potential Indicators of Efficacy and Toxicity of Anticancer Therapies
edited by Beata Kotowicz, Anita Chudecka-Glaz and Anna Dańska-Bidzińska
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2168 | Submission Open
Keywords: cancer; biomarker; molecular biomarkers; immunotherapy; neoadjuvant chemotherapy; targeted therapy; predictive factor; prognostic factor; therapy toxicity; treatment response biomarkers
(This special issue belongs to the Section Cancer Therapy)
Oncology: State-of-the-Art Research in The Netherlands
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2118 | Submission Open
Keywords: cancer research; oncology; The Netherlands; cutting-edge; translational studies
How Ubiquitin and Ubiquitination Affect Cancer Progression
edited by Anna A. Sablina
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2038 | Submission Open
Keywords: cancer ubiquitinome; ubiquitin ligases in cancer; deubiquitinating enzymes in cancer; proteasome pathway; protein stability; non-degrative ubiquitination; PROTACs for cancer treatment
(This special issue belongs to the Section Molecular Cancer Biology)
Multidisciplinary Management of Rectal Cancer
edited by Hiroshi Doi
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1955 | Submission Open
Keywords: rectal cancer; neoadjuvant radiotherapy; preoperative radiotherapy; total neoadjuvant therapy; watch-and-wait strategy; stereotactic body radiotherapy; particle therapy; therapeutic response assessment; biomarkers; radiomics
(This special issue belongs to the Section Cancer Therapy)
Palliative Care and Pain Management in Cancer
edited by María Fernández-Gonzáles and Moira O'Connor
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1738 | Submission Open
Keywords: pain; quality of life; palliative care; non-pharmacological; pharmacological; cancer; metastasis; advanced cancer
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cardio-Oncology: An Emerging Paradigm in Modern Medicine: 2nd Edition
edited by Rohit Moudgil
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1591 | Submission Open
Keywords: cardio-oncology; CTRCD; arrhythmias; anthracyclines; anti-her2 therapies; immune checkpoint inhibitors; artificial intelligence; guidelines; emerging research
(This special issue belongs to the Section Cancer Therapy)
Updates on Immune Checkpoint Inhibitors in Hepatocellular Carcinoma
edited by and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1378 | Submission Open
Keywords: hepatocellular carcinoma; immunotherapy; immuno-oncology; immune checkpoint inhibitors; clinical trial; immunological microenvironments
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Overcoming Pitfalls in the Detection and Definition of Clinically Significant Prostate Cancer: Strategies to Improve Screening and Diagnosis
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1145 | Submission Open
Keywords: prostate cancer; PSA; magnetic resonance of the prostate; prostatic tissue-based biomarkers; prostate biopsy; prostate cancer screening
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Stress Response Pathways in Cancer submission deadline 30 Jun 2025 | Viewed by 1124 | Submission Open
Keywords: stress response pathways; stress; stress expression; cancer; malignant neoplasms; cancer patients; mental health; cell repair mechanisms; cell responses; stressors; autophagy; trigger cell death
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Pathophysiology, Diagnosis, and Multidisciplinary Management of Bone Metastases
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1046 | Submission Open
Keywords: magnetic resonance; oncologic; radiotherapy; oncologic diagnostics; bone metastases; lung cancer; breast cancer; prostate cancer; whole-body diffusion-weighted imaging; whole-body MRI
(This special issue belongs to the Section Cancer Metastasis)
Advance in Treatment of Uveal Melanoma submission deadline 30 Jun 2025 | 1 articles | Viewed by 972 | Submission Open
Keywords: uveal melanoma; distant metastases; treatment modalities
(This special issue belongs to the Section Cancer Therapy)
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 30 Jun 2025 | 1 articles | Viewed by 856 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Focus on Focal Therapy for Prostate Cancer
edited by Abhinav Sidana and Samuel Tremblay
submission deadline 30 Jun 2025 | 1 articles | Viewed by 778 | Submission Open
Keywords: focal therapy; prostate cancer treatment; image-guided therapy; oncological outcomes; functional outcome; patient selection; surveillance
(This special issue belongs to the Section Cancer Therapy)
Treatment Response Biomarkers in Hepatocellular Carcinoma: From Basic Science to Clinical Validation
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 667 | Submission Open
Keywords: hepatocellular carcinoma; prognostic biomarkers; liver-directed therapy; immune checkpoint inhibitors; combination therapy
(This special issue belongs to the Section Cancer Therapy)
Oncology: State-of-the-Art Research in Canada
edited by
submission deadline 30 Jun 2025 | Viewed by 661 | Submission Open
Keywords: cancer research; tumor; oncology; Canada
Applications of Imaging Techniques in Neurosurgery
edited by Alessandro Della Puppa and
submission deadline 30 Jun 2025 | Viewed by 585 | Submission Open
Keywords: neurosurgery; imaging; machine learning; augmented reality; surgical planning; segmentation; decision making
(This special issue belongs to the Section Methods and Technologies Development)
Advancements in Personalized Radiation Therapy for Head and Neck Cancer
edited by Shreerang A. Bhide
submission deadline 30 Jun 2025 | Viewed by 566 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
Radiomics in Cancer Diagnosis, Prognosis and Treatment
edited by , , , Davide Farina and Luigi Spiazzi
submission deadline 30 Jun 2025 | Viewed by 531 | Submission Open
Keywords: radiomics; oncology; radiation oncology; personalized medicine; radiology; nuclear medicine; oncological diagnosis; predictive factors in oncology; biomarkers in cancer treatment; radio-biomarkers in oncology
(This special issue belongs to the Section Cancer Therapy)
Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation
edited by and Chris Swain
submission deadline 30 Jun 2025 | Viewed by 511 | Submission Open
Keywords: cancer; survivorship; exercise; physical activity; implementation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Immunotherapy Approaches in Breast Cancer Treatment
edited by Yi Huang and
submission deadline 30 Jun 2025 | Viewed by 483 | Submission Open
Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
The Duality of MYB: Normal and Cancer Cell Functions
edited by
submission deadline 30 Jun 2025 | Viewed by 458 | Submission Open
(This special issue belongs to the Section Molecular Cancer Biology)
Advancements in Technologies for Radiation Biology, Oncology, and Protection
edited by and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 381 | Submission Open
Keywords: radiation biology; oncology; radiation protection; carcinogenesis; multi-omics; radiomics; radiotherapy; biodosimetry; adverse outcome pathway (AOP); personalized medicine
(This special issue belongs to the Section Cancer Informatics and Big Data)
Hematopoietic Stem-Cell Transplantation for Acute Myeloid Leukemia
edited by Nidhi Jyotsana
submission deadline 30 Jun 2025 | 1 articles | Viewed by 367 | Submission Open
Keywords: hematopoietic stem cell transplantation (HSCT); acute myeloid leukemia (AML); leukemic stem cells; optimize transplant protocols
(This special issue belongs to the Section Cancer Pathophysiology)
Artificial Intelligence (AI) in Cancers
edited by Shengyang Peter Wu
submission deadline 30 Jun 2025 | Viewed by 366 | Submission Open
Keywords: transformer architecture; multimodal data integration; cancer diagnosis accuracy; personalized cancer treatment; machine learning in oncology
(This special issue belongs to the Section Methods and Technologies Development)
Burkitt Lymphoma: From Pathogenesis to Current Treatments
edited by Lorenzo Leoncini and
submission deadline 30 Jun 2025 | Viewed by 353 | Submission Open
Keywords: Burkitt lymphoma; high-grade B-cell lymphoma; EBV; NGS; whole-exome sequencing; RNAseq; methylation analysis; tumor microenvironment; immunotherapy; chemotherapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Endometrial Cancer—from Diagnosis to Management
edited by Mingxin Shi and
submission deadline 30 Jun 2025 | Viewed by 351 | Submission Open
Keywords: endometrial cancer; prognosis; diagnosis; novel biomarker; immunotherapy; targeted therapy; prevention
(This special issue belongs to the Section Cancer Therapy)
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