Predictive Biomarkers for Lung Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Biomarkers".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 2205
Special Issue Editor
Special Issue Information
Dear Colleagues,
Lung cancer remains a formidable challenge in oncology, characterized by its diverse subtypes and often aggressive nature. The intricate landscape of lung malignancies, encompassing non-small-cell lung cancer (NSCLC), small-cell lung cancer (SCLC), and various histological subtypes, underscores the need for precise diagnostic and therapeutic strategies. Despite advancements in treatment modalities, the prognosis for many lung cancer patients remains poor, necessitating innovative approaches for early detection and tailored interventions.
In recent years, the role of biomarkers has emerged as a critical frontier in the pursuit of more effective lung cancer management. Biomarkers, ranging from genetic mutations and expression profiles to circulating molecules, hold the promise of revolutionizing both diagnostic precision and treatment outcomes. This Special Issue of the journal Cancers delves into the evolving landscape of biomarker research in lung cancer, aiming to shed light on recent breakthroughs and future directions in this dynamic field.
The advent of targeted therapies has redefined the treatment paradigm for certain subsets of lung cancer, with actionable mutations such as EGFR, ALK, and ROS1 paving the way for personalized medicine. The exploration of novel biomarkers, both predictive and prognostic, is expanding the repertoire of precision therapies. Additionally, immune checkpoint inhibitors have ushered in a new era in the immunotherapy landscape for lung cancer, offering unprecedented responses in a subset of patients.
However, challenges persist, particularly in the context of identifying biomarkers that transcend histological boundaries and predicting treatment responses in the heterogeneous landscape of lung cancer. The search for reliable biomarkers for early detection and monitoring of treatment responses is a focal point of ongoing research.
In this collection of articles, we present an overview of the current state of biomarker research in lung cancer, exploring the significance of emerging markers such as tumor mutational burden, PD-L1 expression, and liquid-biopsy-based approaches. As we navigate the complex terrain of lung cancer biomarkers, the articles within this Special Issue aim to provide valuable insights into the ongoing efforts to unravel the intricacies of this challenging disease. From predictive markers guiding targeted therapies to the dynamic landscape of immunotherapy, we invite readers to explore the forefront of biomarker-driven precision medicine in lung cancer.
Prof. Dr. Ole Hilberg
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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