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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Insight of MRI for Lung Cancer and Thoracic Neoplasm (2nd Edition)

edited by

Katsuo Usuda

submission deadline 18 Mar 2026 | Viewed by 109 | Submission Open

Keywords: oncologic imaging; cancer imaging; imaging of thoracic disease; magnetic resonance imaging (MRI); computed tomography (CT); positron emission tomography– computed tomography (PET-CT); diffusion-weighted magnetic resonance imaging (DWI); economic evaluation; imaging biomarkers

(This special issue belongs to the Section Methods and Technologies Development)

Targeted Therapy of Cholangiocarcinoma

edited by

Rosa Maria Pascale

submission deadline 19 Mar 2026 | Viewed by 65 | Submission Open

Keywords: cholangiocarcinoma; targeted therapy; molecular alterations; immunotherapy; precision medicine

(This special issue belongs to the Section Tumor Microenvironment)

Drug Targeting Therapy in Multiple Myeloma

edited by

Hiroshi Handa

and

Hideto Tamura

submission deadline 20 Mar 2026 | 2 articles | Viewed by 3926 | Submission Open

Keywords: multiple myeloma; novel drug; novel targets; new therapeutic targets; prognosis

(This special issue belongs to the Section Cancer Drug Development)

Cancer Survivors: Late Effects of Cancer Therapy

edited by

Gaurav Kumar

submission deadline 20 Mar 2026 | Viewed by 65 | Submission Open

Keywords: late effects; cancer survivorship; treatment toxicity; long-term outcomes

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Radiation Therapy in Lung Tumors: Recent Trends and Current Issues

edited by

Paul Jules van Houtte

and Sara Ramella

submission deadline 21 Mar 2026 | Viewed by 27 | Submission Open

Keywords: lung cancer; immunotherapy; chemotherapy; PET-CT; surgery; oligo-metastases

(This special issue belongs to the Section Cancer Therapy)

Bacterial Infections and Cancer Risk: From Biological Mechanisms to Clinical Realities

edited by

Skander Hathroubi

and Shuai Hu

submission deadline 25 Mar 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: bacterial infections; cancer risk; biological mechanisms; treatment modalities; therapeutic strategies

(This special issue belongs to the Section Infectious Agents and Cancer)

Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion

edited by

Agata Kabała-Dzik

submission deadline 28 Mar 2026 | Viewed by 77 | Submission Open

Keywords: urokinase-type plasminogen receptor; uPAR; inflammation; cancer; migration; invasion

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer Immunotherapy: Focus on Immune Checkpoint Inhibitors and Immune Modulators

edited by

Katsuaki Ieguchi

submission deadline 30 Mar 2026 | 3 articles | Viewed by 5071 | Submission Open

Keywords: PD-1; PD-L1; CTLA-4; immune checkpoint molecule; immune checkpoint inhibitor; tumor microenvironment; drug resistance; biomarker; BiTE; BiCE

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Neoadjuvant Therapy for Pancreatic Cancer

edited by Brice Chanez

submission deadline 30 Mar 2026 | Viewed by 111 | Submission Open

Keywords: induction treatment; biomarkers; chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Quality and Clinical Outcomes Improvement in the Management of Oncology Patients (2nd Edition)

edited by

Dimitrios E. Magouliotis

submission deadline 30 Mar 2026 | Viewed by 19 | Submission Open

Keywords: oncology; surgical oncology; quality improvement; clinical outcomes; patient safety

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Women’s Health and Gynaecological Cancers: From Nutrition and Environmental Factors to Novel Diagnostics and Therapies

edited by

and

submission deadline 31 Mar 2026 | 9 articles | Viewed by 19327 | Submission Open

Keywords: breast cancer; ovarian cancer; cervical cancer; endometrial cancer; nutrition; obesity; environmental factors; women's health; gynaecological cancers

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Gastric Cancer Surgery: Gastrectomy, Risk, and Related Prognosis

edited by

Wojciech Piotr Polkowski

submission deadline 31 Mar 2026 | 4 articles | Viewed by 5922 | Submission Open

Keywords: gastric cancer; surgical treatment; gastrectomy; outcome; minimally invasive surgical

(This special issue belongs to the Section Clinical Research of Cancer)

Advancements in Treatment Approaches for AML

edited by

Semra Aydin

and

Raheel Iftikhar

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4527 | Submission Open

Keywords: AML treatment; allogeneic HSCT; novel targeted therapeutic agents; diagnostic; treatment strategies

(This special issue belongs to the Section Methods and Technologies Development)

The Oral Microbiome and Its Link to Oral Cancer: Exploring the Role of Infectious Agents

edited by

Tomoaki Shintani

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2909 | Submission Open

Keywords: oral microbiome; oral cancer; infectious agents; microbial dysbiosis; host– microbe interactions

(This special issue belongs to the Section Infectious Agents and Cancer)

Intratumoral Heterogeneity in Brain Cancers

edited by Michael Oldham

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2470 | Submission Open

Keywords: intratumoral heterogeneity; brain; clonal evolution; tumor microenvironment; multiomics

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Renal Cell Carcinoma

edited by Philipp Ivanyi and Hendrik Eggers

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2025 | Submission Open

Keywords: renal cell carcinoma; treatment; metastatic; prediction; medical treatment; immunotherapy; multimodal therapy; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Cardio-Oncology: An Emerging Paradigm in Modern Medicine: 2nd Edition

edited by Rohit Moudgil

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1965 | Submission Open

Keywords: cardio-oncology; CTRCD; arrhythmias; anthracyclines; anti-her2 therapies; immune checkpoint inhibitors; artificial intelligence; guidelines; emerging research

(This special issue belongs to the Section Cancer Therapy)

Advances in Invasive Breast Cancer: Treatment and Prognosis (2nd Edition)

edited by

Eleni Timotheadou

and Emmanouil Saloustros

submission deadline 31 Mar 2026 | 3 articles | Viewed by 1563 | Submission Open

Keywords: ER+/HER2– breast cancer; HER2+ breast cancer; triple-negative breast cancer; treatment toxicity and quality of life; survivorship issues

(This special issue belongs to the Section Cancer Therapy)

The Role of Viruses in the Development of Cancer

edited by

George Eric Blair

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1320 | Submission Open

Keywords: DNA and RNA tumour viruses; HPV; EBV; KSHV; HCV; HBV; HTLV1; McPyV

(This special issue belongs to the Section Infectious Agents and Cancer)

Immunotherapy in Urothelial Carcinoma

edited by

Akinori Minato

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1313 | Submission Open

Keywords: bladder cancer; upper tract urothelial carcinoma; immune checkpoint inhibitors; tumor microenvironment; biomarkers for immunotherapy; combination therapy; neo-adjuvant/adjuvant immunotherapy; resistance mechanisms; novel immunotherapeutic approaches; personalized medicine

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer

edited by

Greta Alì

and

Maria Giovanna Mastromarino

submission deadline 31 Mar 2026 | 1 articles | Viewed by 986 | Submission Open

Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Minimally Invasive Therapies in Urologic Cancers

edited by Eric M. Walser and

Guglielmo Manenti

submission deadline 31 Mar 2026 | 1 articles | Viewed by 548 | Submission Open

Keywords: laparoscopic surgery; robotic-assisted surgery; ablation; high-intensity focused ultrasound; partial nephrectomy; minimally invasive procedures; urologic cancers

(This special issue belongs to the Section Methods and Technologies Development)

Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation

edited by

Lara Edbrooke

and Chris Swain

submission deadline 31 Mar 2026 | Viewed by 525 | Submission Open

Keywords: cancer; survivorship; exercise; physical activity; implementation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Development of Biomarkers and Antineoplastic Drugs in Solid Tumors

edited by

Rosa Falcone

, Sofia Verkhovskaia and Michela Roberto

submission deadline 31 Mar 2026 | 1 articles | Viewed by 523 | Submission Open

Keywords: solid tumors; drugs; biomarkers; immunotherapy; targeted therapy; artificial intelligence

(This special issue belongs to the Section Cancer Drug Development)

Advances on Imaging and Treatment of Head and Neck Cancer

edited by Yading Yuan, Vishruta A. Dumane,

Haibo Lin

and Luqman Dad

submission deadline 31 Mar 2026 | Viewed by 340 | Submission Open

Keywords: head and neck cancer; medical imaging; robotic surgery; image-guided radiation therapy; proton radiotherapy; online adaptive radiotherapy; artificial intelligence; machine learning

(This special issue belongs to the Section Cancer Therapy)

Significance of KRAS Gene Mutations in Colorectal Cancer (2nd Edition)

edited by

Grazia Palomba

and

Maria Cristina Sini

submission deadline 31 Mar 2026 | 1 articles | Viewed by 278 | Submission Open

Keywords: KRAS; colorectal cancer; target therapy; mechanism; treatment targets

(This special issue belongs to the Section Molecular Cancer Biology)

Imaging and Liquid Biopsy Biomarkers for Cancer Diagnosis and Treatment (2nd Edition)

edited by

Mark Jesus M. Magbanua

and

Wen Li

submission deadline 31 Mar 2026 | Viewed by 91 | Submission Open

Keywords: cancer imaging; liquid biopsy; cancer diagnosis; treatment response; prognosis; metastasis; circulating tumor cells; disseminated tumor cells; circulating tumor DNA; circulating tumor RNA

(This special issue belongs to the Section Methods and Technologies Development)

Colorectal Cancer Liver Metastases

edited by

Piero Boraschi

and

Francescamaria Donati

submission deadline 31 Mar 2026 | Viewed by 90 | Submission Open

Keywords: liver metastases; colorectal cancer; treatment; imaging; oncologic strategy

(This special issue belongs to the Section Cancer Metastasis)

Immune Landscape of Multiple Myeloma

edited by Muhamed Baljevic and

Shebli Atrash

submission deadline 31 Mar 2026 | Viewed by 80 | Submission Open

Keywords: myeloma; immune; T cells; therapy; fitness

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Genetic Alterations and the Tumor Microenvironment

edited by Shanye Yin

submission deadline 31 Mar 2026 | Viewed by 79 | Submission Open

Keywords: tumor microenvironment; cancer immunology; immune checkpoint blockade; somatic mutations; T cell signaling; immune evasion; macrophage polarization; cancer immunotherapy resistance; single-cell transcriptomics; spatial analysis

(This special issue belongs to the Section Tumor Microenvironment)

Recent Advances in the Understanding of Myelodysplastic Syndrome and Acute Myeloid Leukemia (2nd Edition)

edited by

Ioannis Mitroulis

, Konstantinos Liapis and

Eleni Gavriilaki

submission deadline 31 Mar 2026 | Viewed by 74 | Submission Open

Keywords: myelodysplastic syndrome; acute myeloid leukemia; bone marrow micro-environment; targeted therapies; hematopoietic stem cell; leukemic stem cell; hematopoietic stem cell transplantation

(This special issue belongs to the Section Cancer Therapy)

Mitochondrial Metabolism in Cancer Immune Responses

edited by

Jae Ho Seo

and Kiwon Lee

submission deadline 31 Mar 2026 | Viewed by 72 | Submission Open

Keywords: mitochondria; cancer metabolism; immune response; tumor microenvironment (TME); immunometabolism; mitochondrial reprogramming; reactive oxygen species (ROS); cancer immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Proteomic and Oncogenic Biomarkers in Gastrointestinal Cancer

edited by

Marta Lukaszewicz-Zajac

and

Adrianna Romanowicz

submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open

Keywords: tumor biomarkers; early detection; tumor progression; carcinogenesis; inflammatory mediators; gastrointestinal cancer; prognostic biomarkers

(This special issue belongs to the Section Cancer Biomarkers)

Proteomics in Skin Cancer: Recent Advances

edited by

Ali Azimi

and Beatrice Dyring-Andersen

submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open

Keywords: proteomics; skin cancer; mass spectrometry; melanoma; non-melanoma skin cancers; biomarkers

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Strategies to Fight Metastatic Breast Cancer

edited by

Fernando Schmitt

and

Nuno Vale

submission deadline 31 Mar 2026 | Viewed by 65 | Submission Open

Keywords: breast cancer; metastasis; targeted therapy; biomarkers; personalized medicine; prognosis

(This special issue belongs to the Section Molecular Cancer Biology)

Screening and Surveillance of Gastrointestinal and Pancreatic Cancers

edited by Darina Kohoutová and

Jan Bures

submission deadline 31 Mar 2026 | Viewed by 64 | Submission Open

Keywords: screening; surveillance; GI cancer; pancreatic precancerous lesions

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Quantitative Imaging, AI, and Novel Imaging Techniques for Precision Radiology in Prostate Cancer

edited by Rulon R. Mayer,

Charles Simone

and

Yuan Yuan

submission deadline 31 Mar 2026 | Viewed by 61 | Submission Open

Keywords: prostate cancer; multi-parametric MRI (mpMRI); bi-parametric MRI; positron emission tomography (PET); computed tomography (CT); ultrasound (US); artificial intelligence (AI); convolutional neural network; visual language model; computer-aided diagnosis; spatially registered multi-parametric MRI; prostate specific membrane antigen in PET/CT

(This special issue belongs to the Section Methods and Technologies Development)

The Development of Immunotherapies to Treat Lymphoma

edited by

Christina Kalpadakis

submission deadline 31 Mar 2026 | Viewed by 57 | Submission Open

Keywords: lymphoma immunotherapy; CAR T-cell therapy; immune checkpoint inhibitors; monoclonal antibodies; personalized immunotherapy

Lipids and Small Metabolites in Cancer—2nd Edition

edited by

Zsolt Balogi

and

Laszlo Vigh

submission deadline 31 Mar 2026 | Viewed by 52 | Submission Open

Keywords: lipid; small metabolites; cancer; metabolome- and lipidome-related mechanisms; amino acids; fatty acids; numerous components of biochemical pathways

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical and Surgical Outcomes in the Management of Extremity Soft Tissue Sarcomas (2nd Edition)

edited by

Matthew T. Houdek

submission deadline 31 Mar 2026 | Viewed by 49 | Submission Open

Keywords: soft tissue sarcoma; outcome; limb salvage; radiotherapy; surgery

(This special issue belongs to the Section Cancer Therapy)

Cancer Drug Discovery and Development: 2nd Edition

edited by Gary Piazza

submission deadline 31 Mar 2026 | Viewed by 45 | Submission Open

Keywords: signal transduction inhibitors; small-molecule inhibitors; antibodies; PROTOC; immunotherapy; medicinal chemistry; chemical optimization; high-throughput screening

(This special issue belongs to the Section Cancer Drug Development)

Robotic and Thoracoscopic Surgery for Thoracic Oncology

edited by

Elisa Meacci

submission deadline 31 Mar 2026 | Viewed by 45 | Submission Open

Keywords: robotic-assisted thoracic surgery; video-assisted thoracoscopic surgery (VATS); lung cancer surgery; esophageal cancer; thymic tumors; minimally invasive surgery; pleural tumors; chest wall tumors; mediastinal surgery; thoracic oncology

(This special issue belongs to the Section Clinical Research of Cancer)

Flow Cytometry and Beyond: Innovative Cytometric Approaches in Cancer Detection, Profiling, and Therapeutic Monitoring

edited by

George Vartholomatos

Georgios Markopoulos

, Lefkothea Dova and Savvas Dimitriadis

submission deadline 31 Mar 2026 | Viewed by 44 | Submission Open

Keywords: cancer diagnostics; next-generation flow cytometry; AI-driven cytometry; high-dimensional single-cell analysis; cancer immunophenotyping; cytometry-based biomarkers; tumor heterogeneity; extracellular vesicles; spectral and mass cytometry; intraoperative flow cytometry

(This special issue belongs to the Section Methods and Technologies Development)

Real-World Clinical Studies in Acute Leukemia

edited by

Anna Candoni

submission deadline 31 Mar 2026 | Viewed by 40 | Submission Open

Keywords: acute myeloid leukemia (AML); acute lymphoid leukemia (ALL); refractory/relapsed leukemia; target therapy; FLT3 inhibitors; IDH (1-2) inhibitors; venetoclax; hypomethylating agents; stem cell transplantation (SCT); minimal residual disease (MRD); MRD-driven therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Contemporary Lung Cancer Nodal Staging and Evolving Therapeutic Paradigms

edited by

Takahiro Nakajima

submission deadline 31 Mar 2026 | Viewed by 33 | Submission Open

Keywords: ninth TNM classification; nodal staging; endoscopic/endobronchial ultrasound; neoadjuvant/adjuvant therapy; biomarker testing

(This special issue belongs to the Section Cancer Therapy)

TGF-β Signaling in the Tumor Microenvironment: Dual Roles in Cancer Progression and Therapy

edited by

Byung-Gyu Kim

submission deadline 31 Mar 2026 | Viewed by 31 | Submission Open

Keywords: TGF-β signaling; tumor microenvironment; solid tumors; hematologic malignancies; immune modulation; therapeutic resistance; TGF-β pathway inhibitors; cancer immunotherapy

(This special issue belongs to the Section Tumor Microenvironment)

Deep Learning and Radiomics for Cancer Diagnosis, Staging, and Treatment Response

edited by Mohamed Shehata,

Mostafa Elhosseini

Mahmoud Badawy

and Hanaa ZainEldin

submission deadline 31 Mar 2026 | Viewed by 26 | Submission Open

Keywords: radiomics; deep learning; cancer imaging; diagnosis; staging; treatment response; machine learning; medical image analysis; precision oncology; federated learning; AI in healthcare

(This special issue belongs to the Section Methods and Technologies Development)

Gene Fusions in Cancer

edited by Christopher R. McEvoy and

Ing Soo Tiong

submission deadline 31 Mar 2026 | Viewed by 22 | Submission Open

Keywords: gene fusions; targeted therapy; cancer diagnostics; molecular pathology

(This special issue belongs to the Section Molecular Cancer Biology)

Diagnosis and Therapy in Urothelial Cancer

edited by

Giuseppe Palermo

submission deadline 31 Mar 2026 | Viewed by 18 | Submission Open

Keywords: urothelial cancer; bladder cancer; biomarkers; robotic surgery; immunotherapy; upper tract urothelial carcinoma

(This special issue belongs to the Section Cancer Therapy)

Modern Approaches in Gastrointestinal (GI) Oncology: From Bench to Bedside

edited by

Francesco Fiorica

submission deadline 31 Mar 2026 | Viewed by 16 | Submission Open

Keywords: gastrointestinal oncology; radiotherapy and immunotherapy; translational cancer research; radiogenomics and AI; biomarkers and personalized treatment

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 901-950 on page 19 of 23.

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