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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Clinical Surgery for Gynecological Cancers

edited by

Sebastian Szubert

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1559 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; gynecological surgery; gynecological oncology; reconstructive surgery; pelvic exenteration; supportive cancer care

(This special issue belongs to the Section Methods and Technologies Development)

Integrating Chemotherapy and Immunotherapy for Head and Neck Cancer

edited by Ken Saijo

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1464 | Submission Open

Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy

(This special issue belongs to the Section Cancer Metastasis)

Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management

edited by

Mateusz Czajkowski

and Marcin Matuszewski

submission deadline 15 Jul 2026 | 1 articles | Viewed by 611 | Submission Open

Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology

Robotic Versus Laparoscopic Surgery for Colorectal Cancer

edited by Richard Garfinkle and Nicholas P. McKenna

submission deadline 15 Jul 2026 | Viewed by 128 | Submission Open

Keywords: colon cancer; rectal cancer; colorectal cancer; robotic surgery; laparoscopic surgery; transanal surgery; minimally invasive surgery

(This special issue belongs to the Section Methods and Technologies Development)

Tumor Microenvironment of Breast Cancer—2nd Edition

edited by

Masanori Oshi

submission deadline 15 Jul 2026 | Viewed by 101 | Submission Open

Keywords: breast cancer; tumor microenvironment; TME; stromal cells

(This special issue belongs to the Section Tumor Microenvironment)

Pancreatic Cancer: Genomics, Therapy and Survival

edited by Hisanobu Ogata

submission deadline 15 Jul 2026 | Viewed by 74 | Submission Open

Keywords: pancreas; cancer; treatment; oncolytic virus; stromal cell; cancer-associated fibroblast (CAF)

(This special issue belongs to the Section Cancer Therapy)

Molecular Signatures of Therapy: Biomarkers Predicting Response and Relapse in Cancer

edited by

Antonis Giakountis

submission deadline 15 Jul 2026 | Viewed by 66 | Submission Open

Keywords: molecular biomarkers; therapeutic response; disease relapse; precision oncology; liquid biopsy; predictive biomarkers; multi-omics integration; minimal residual disease; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Thermal Ablation in the Management for Colorectal Liver Metastases: 2nd Edition

edited by

Martijn Meijerink

and

Robbert S. S. Puijk

submission deadline 15 Jul 2026 | Viewed by 58 | Submission Open

Keywords: image-guided therapies; colorectal liver metastases (CRLMs); thermal ablation; (non-)thermal and radiation-related treatment; interventional and radiation oncology

(This special issue belongs to the Section Cancer Metastasis)

Myelodysplastic Neoplasms (MDS) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy

edited by

Ling Zhang

, David Sallman and Deniz Peker

submission deadline 15 Jul 2026 | Viewed by 44 | Submission Open

Keywords: myelodysplastic syndromes/myelodysplastic neoplasms (MDS); myelodysplastic/myeloproliferative neoplasm; chronic myelomonocytic leukemia (CMML); diagnosis; mutations; IPSS-R; IPSS-M; hypomethylation agents; targeted therapy; hematopoietic stem cell transplant (HSCT)

(This special issue belongs to the Section Molecular Cancer Biology)

Robotic and Laparoscopic Techniques for Urologic Cancers: Innovations in Resection and Reconstruction

edited by

Tobias Klatte

submission deadline 15 Jul 2026 | Viewed by 40 | Submission Open

Keywords: robot-assisted surgery; surgical robotics; minimally invasive surgery; artificial intelligence; complications; prognostic and predictive factors; planning; perioperative care

(This special issue belongs to the Section Methods and Technologies Development)

Radiologic Imaging of Hepatocellular Carcinomas

edited by

Masakatsu Tsurusaki

submission deadline 15 Jul 2026 | Viewed by 36 | Submission Open

Keywords: machine learning/deep learning; radiomics; imaging biomarkers; hepatocellular carcinoma; CT; MRI; PET/CT; Gd-EOB-DTPA; LI-RADS; therapeutic response assessment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Personalizing Head and Neck Cancer Care

edited by

Inge Wegner

and

G. B. Halmos

submission deadline 17 Jul 2026 | Viewed by 102 | Submission Open

Keywords: head and neck cancer; personalized treatment; targeted therapy; prehabilitation; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Skin Cancer: Epidemiology, Management and New Therapies

edited by

Gerardo Cazzato

and Francesco Fortarezza

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6643 | Submission Open

Keywords: skin cancer; melanoma; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; adnexal tumor; metastatic cutaneous neoplasms; epidemiology; management; therapy

(This special issue belongs to the Section Cancer Therapy)

Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 20 Jul 2026 | 1 articles | Viewed by 2547 | Submission Open

Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers

(This special issue belongs to the Section Cancer Therapy)

Advances in Early Diagnosis and Minimally Invasive Management in Breast Cancer

edited by

Graziella Di Grezia

submission deadline 20 Jul 2026 | 1 articles | Viewed by 2246 | Submission Open

Keywords: precision medicine; breast cancer prevention; cancer detection; early diagnosis; therapeutic strategies; artificial intelligence; image analysis; risk predictors

(This special issue belongs to the Section Methods and Technologies Development)

HIV-Associated Lymphoid Neoplasms (2nd Edition)

edited by

José-Tomás Navarro

and

Kai Hübel

submission deadline 20 Jul 2026 | Viewed by 123 | Submission Open

Keywords: B-cell lymphoma; HIV; AIDS; Epstein– Barr virus; epidemiology; pathogenesis; prognosis

(This special issue belongs to the Section Infectious Agents and Cancer)

Breaking the Cycle: CDK4/6 Inhibitors Take on Cancers

edited by

Navid Sobhani

submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open

Keywords: CDK4/6 inhibitors; p16; targeted therapy; tumor microenvironment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Pediatric Liver Cancer Research

edited by Sarah E. Woodfield

submission deadline 20 Jul 2026 | Viewed by 28 | Submission Open

Keywords: hepatoblastoma; pediatric hepatocellular carcinoma; fibrolamellar carcinoma; malignant rhabdoid tumor; undifferentiated embryonal sarcoma; chemotherapy; targeted therapy; immunotherapy; surgery

(This special issue belongs to the Section Pediatric Oncology)

Novel Diagnostic and Therapeutic Approaches in Urologic Oncology

edited by

Whi-An Kwon

submission deadline 21 Jul 2026 | 1 articles | Viewed by 1832 | Submission Open

Keywords: urologic oncology; liquid biopsy; immunotherapy; artificial intelligence; targeted therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Current Advances in Surgical and Systemic Treatment of Breast Cancer

edited by

Kwok-Leung Cheung

and

Srinivasan Madhusudan

submission deadline 23 Jul 2026 | Viewed by 90 | Submission Open

Keywords: breast cancer; breast surgery; oncoplastic surgery; systemic therapy; biomarkers; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Exosomes and Cancer Biomarkers

edited by

Nathan Wall

submission deadline 24 Jul 2026 | Viewed by 392 | Submission Open

Keywords: exosomes; cancer biomarkers; liquid biopsy; tumor microenvironment; molecular diagnosis

(This special issue belongs to the Section Cancer Biomarkers)

Antibodies and Their Derivatives in Cancer Immunotherapy for Gastrointestinal Cancers

edited by

Kiran Kundu

and

Susmita Ghosh

submission deadline 24 Jul 2026 | Viewed by 34 | Submission Open

Keywords: gastrointestinal cancer; immunotherapy; immune checkpoint blocker; monoclonal antibody; CAR; bispecific antibody; T cell engager; NK cell engager

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and Senthamizhchelvan Srinivasan

submission deadline 25 Jul 2026 | Viewed by 104 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Precision Medicine and Targeted Therapies in Neuroblastoma

edited by

Nilay Shah

submission deadline 30 Jul 2026 | 2 articles | Viewed by 2212 | Submission Open

Keywords: pediatric oncology; solid tumors; targeted therapies; biomarkers of response; novel combination therapies; tumor microenvironment; integrative diagnostics; theranostics; telomere maintenance mechanisms; neuroblastoma

(This special issue belongs to the Section Clinical Research of Cancer)

Ovarian Cancer: Pathogenesis, Molecular Mechanism and Opportunities for Interventions

edited by

Apriliana Kartikasari

submission deadline 30 Jul 2026 | 1 articles | Viewed by 1634 | Submission Open

Keywords: ovarian cancer; pathogenesis; therapy; biomarkers; molecular

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Machine Learning and Artificial Intelligence in Cancer Diagnostic and Monitoring

edited by

Junfeng Wang

submission deadline 30 Jul 2026 | 2 articles | Viewed by 833 | Submission Open

Keywords: machine learning; artificial intelligence; implementation; fairness; uncertainty

(This special issue belongs to the Section Methods and Technologies Development)

Cutting-Edge Nanomedicine Advancements in Cancer Disease

edited by

Ana Isabel Torres-Suárez

and

Ana Isabel Fraguas-Sánchez

submission deadline 30 Jul 2026 | Viewed by 317 | Submission Open

Keywords: active targeting; breast cancer; drug delivery; liposomes; lung cancer; metallic nanoparticles; polymeric nanoparticles; theragnostic

(This special issue belongs to the Section Methods and Technologies Development)

Flow Cytometry and Molecular Studies in Hematological Malignancies

edited by Kirill A. Lyapichev

submission deadline 30 Jul 2026 | Viewed by 186 | Submission Open

Keywords: flow cytometry; molecular studies; hematological neoplasms; lymphoma; leukemia

(This special issue belongs to the Section Molecular Cancer Biology)

Multidisciplinary Approach to Bladder Cancer Treatment and Care

edited by Bente Thoft Jensen and

Susanne Vahr Lauridsen

submission deadline 30 Jul 2026 | Viewed by 125 | Submission Open

Keywords: non-muscle-invasive bladder cancer; muscle-invasive bladder cancer; health-related quality of life; nutrition; prehabilitation; sexual health; nursing leadership; implementation; new technologies

(This special issue belongs to the Section Cancer Therapy)

Resection and Reconstruction for Breast Cancer

edited by Radoslaw Tarkowski and

Gilles Houvenaeghel

submission deadline 30 Jul 2026 | Viewed by 104 | Submission Open

Keywords: oncoplastic breast surgery; breast reconstruction; breast cancer

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Surgical Management of Ovarian Cancer

edited by Lina Salman

submission deadline 30 Jul 2026 | Viewed by 78 | Submission Open

Keywords: ovarian cancer; surgical management; complications; HIPEC; survival

(This special issue belongs to the Section Clinical Research of Cancer)

Cellular Plasticity, Metabolic Adaptations and Therapeutic Strategies in Breast Cancer

edited by

Kunwar Somesh Vikramdeo

submission deadline 30 Jul 2026 | Viewed by 38 | Submission Open

Keywords: breast cancer; cellular plasticity; metabolic reprogramming; tumor microenvironment; therapy resistance; epithelial– mesenchymal transition (EMT); cancer stem cells; redox metabolism; mitochondrial pathways; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Systematic Reviews and Meta-Analyses of Genitourinary Cancers (2nd Edition)

edited by

Giorgio Treglia

and Ursula Maria Vogl

submission deadline 31 Jul 2026 | 6 articles | Viewed by 8868 | Submission Open

Keywords: systematic review; meta-analysis; oncology; genitourinary cancers; diagnosis; therapy

(This special issue belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)

Evolving Understanding of the Epidemiology of Thyroid Cancer

edited by

Marco Capezzone

and

Anello Marcello Poma

submission deadline 31 Jul 2026 | 2 articles | Viewed by 7040 | Submission Open

Keywords: thyroid cancer; epidemiology; incidence; time trends; mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

The Roles of Deep Learning in Cancer Radiotherapy

edited by Zhen Tian

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5656 | Submission Open

Keywords: radiotherapy; deep learning; artificial Intelligence; tumor detection; image segmentation; treatment planning; outcome prediction; radiomics

(This special issue belongs to the Section Cancer Informatics and Big Data)

Circulating Tumor Cells (CTCs) and the Implementation of Liquid Biopsy (2nd Edition)

edited by

Dario Marchetti

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2900 | Submission Open

Keywords: liquid biopsy; metastatic biomarkers; CTCs isolation technologies; tumor heterogeneity; clinical CTC applications

(This special issue belongs to the Section Tumor Microenvironment)

Pituitary Tumors: Clinical and Surgical Challenges

edited by

Michal Hlavac

and

Andrej Pala

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1569 | Submission Open

Keywords: pituitary; neuroendocrine tumors; transsphenoidal endoscopic surgery; MRI imaging; quality of life

(This special issue belongs to the Section Clinical Research of Cancer)

Clinical Treatment and Prognosis of Breast Cancer

edited by Roxana Popescu and

Ionut Marcel Cobec

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: breast cancer; targeted therapy; personalized therapy; alternative approach; tumor biology; gynecologic oncology

(This special issue belongs to the Section Clinical Research of Cancer)

Biologic Advancements in Childhood and Adolescent Cancers: From Disease Mechanisms to Precision Therapies

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 953 | Submission Open

Keywords: pediatric oncology; precision therapies; molecular vulnerabilities; biomarker-driven trials; disease mechanisms

(This special issue belongs to the Section Pediatric Oncology)

The Emerging Role of Multiplexed Imaging for Cancer Diagnosis and Therapy (2nd Edition)

edited by

Li Liu

and

Yicheng Ni

submission deadline 31 Jul 2026 | 1 articles | Viewed by 939 | Submission Open

Keywords: multiplexed imaging; cancer diagnosis; molecular imaging; novel contrast agents; targeted radionuclide tracers theragnostics; personalized cancer therapy; therapeutic monitoring; imaging biomarkers; clinical translation

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Molecular Genomics in Brain Tumors

edited by

Marta Mellai

and

Renzo Boldorini

submission deadline 31 Jul 2026 | 1 articles | Viewed by 884 | Submission Open

Keywords: glioma; signaling pathways; metabolism; microbiota– gut– brain axis; biomarkers; therapeutics; immunotherapy

(This special issue belongs to the Section Cancer Pathophysiology)

New Trends in Urologic Oncology: Surgical Treatments, Robotics, Biomarkers, Diagnostic Tools, and Innovative Therapies

edited by Alessandro Uleri and

Roberto Contieri

submission deadline 31 Jul 2026 | 1 articles | Viewed by 821 | Submission Open

Keywords: prostate cancer; renal cancer; bladder cancer; UTUC; testicular cancer; penile cancer; biomarkers

(This special issue belongs to the Section Clinical Research of Cancer)

Hybrid Molecular Imaging Approaches in Cancer: PET/CT, PET/MRI, and Beyond

edited by

Luca Urso

submission deadline 31 Jul 2026 | 1 articles | Viewed by 760 | Submission Open

Keywords: PET/CT; PET/MRI; hybrid molecular imaging; radiomics and artificial intelligence; conventional PET Radiotracers; emerging PET Radiotracers; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Cancer Metastasis in 2025–2026

edited by

Lance A. Liotta

submission deadline 31 Jul 2026 | 1 articles | Viewed by 719 | Submission Open

Keywords: immunotherapy; tumor suppression; cancer metastasis; invasion

(This special issue belongs to the Section Cancer Metastasis)

Mechanisms of Therapy Resistance in Cancers—2nd Edition

edited by

Birandra K. Sinha

submission deadline 31 Jul 2026 | 1 articles | Viewed by 618 | Submission Open

Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance

(This special issue belongs to the Section Cancer Drug Development)

Novel Insights into Glioblastoma and Brain Metastases (2nd Edition)

edited by

Sanjay K. Srivastava

submission deadline 31 Jul 2026 | 1 articles | Viewed by 601 | Submission Open

Keywords: glioblastoma; brain metastasis; surgery; radiation; chemotherapy; blood– brain barrier; immunotherapy; novel targets; oncogenes; tumor heterogeneity; drug discovery

(This special issue belongs to the Section Cancer Metastasis)

CRISPR in Cancer Biology and Therapy: 2nd Edition

edited by

Shun-Qing Liang

submission deadline 31 Jul 2026 | Viewed by 457 | Submission Open

Keywords: cancer drug resistance; CRISPR screens; CRISPR-related technology; base editing; prime editing; off-target analysis; adeno-associated virus

(This special issue belongs to the Section Methods and Technologies Development)

Melanoma: Pathology and Translational Research—2nd Edition

edited by

Alessio Giubellino

Carlos Torres-Cabala

and Jose A. Plaza

submission deadline 31 Jul 2026 | Viewed by 310 | Submission Open

Keywords: melanoma; histopathology; dermatopathology; molecular profiling; biomarkers; digital pathology; translational studies; cancer therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Recent Developments on PET-CT in Multiple Myeloma

edited by Carmelo Caldarella

submission deadline 31 Jul 2026 | Viewed by 157 | Submission Open

Keywords: PET/CT; multiple myeloma; novel radiopharmaceuticals; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative and Adjuvant Immunotherapy in Lung Cancer: New Strategies, Biomarkers, Patient Selection and Toxicity Management

edited by

Xabier Mielgo Rubio

Felipe Couñago

and Juan Carlos Trujillo-Reyes

submission deadline 31 Jul 2026 | Viewed by 138 | Submission Open

Keywords: non-small-cell lung cancer (NSCLC); immunotherapy; neoadjuvant treatment; adjuvant treatment; perioperatory treatment; chemotherapy; surgery; radiotherapy; toxicity; biomarkers

(This special issue belongs to the Section Tumor Microenvironment)

Displaying special issue 901-950 on page 19 of 24.

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