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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hepatocellular Carcinoma Progression and Metastasis

edited by

Ching-Sheng Hsu

submission deadline 10 May 2026 | 1 articles | Viewed by 1340 | Submission Open

Keywords: hepatocellular carcinoma; tumor progression; metastasis; liver cancer; angiogenesis; epithelial– mesenchymal transition; tumor microenvironment; molecular pathways; biomarkers; targeted therapy; systemic therapy

(This special issue belongs to the Section Cancer Metastasis)

Artificial Intelligence for Network-Based Oncomarker Discovery and Cancer Prediction

edited by Oleg Blyuss

submission deadline 10 May 2026 | Viewed by 48 | Submission Open

Keywords: artificial intelligence (AI); network-based biomarkers; graph neural networks (GNNs); multi-omic integration; cancer prediction; oncomarker discovery; prognostic and predictive biomarkers

(This special issue belongs to the Section Cancer Informatics and Big Data)

Systemic Treatment for Breast Cancer

edited by

Luigia Stefania Stucci

submission deadline 12 May 2026 | Submission Open

Keywords: breast cancer; biomarker; treatment; management

(This special issue belongs to the Section Cancer Therapy)

Infectious Agents and Cancer in Children and Adolescents

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 15 May 2026 | 3 articles | Viewed by 6079 | Submission Open

Keywords: infectious agents; immune system; tumor development; immunological memory; oncolytic viruses

(This special issue belongs to the Section Infectious Agents and Cancer)

Endoscopic Advances in Gastrointestinal Oncology

edited by Eduardo Rodrigues-Pinto

submission deadline 15 May 2026 | 1 articles | Viewed by 3515 | Submission Open

Keywords: endoscopic oncology; endoscopic screening; endoscopic resection; endoscopic palliation; staging

(This special issue belongs to the Section Cancer Therapy)

Integrative Histopathological–Molecular–Computational Analysis of Primary Brain Tumors

edited by

Adriana Olar

submission deadline 15 May 2026 | Viewed by 520 | Submission Open

Keywords: brain tumor histopathology; neuropathology; molecular pathology; digital pathology; artificial intelligence; bioinformatics; computational pathology; deep learning

(This special issue belongs to the Section Cancer Informatics and Big Data)

Gene Editing and Delivery for Cancer Therapy (2nd Edition)

edited by

Yong Teng

and

Yamin Li

submission deadline 15 May 2026 | Viewed by 118 | Submission Open

Keywords: gene therapy; gene editing; gene delivery; oncolytic viruses; nanomaterial; peptides; nanostructures; exosomes; translational science

(This special issue belongs to the Section Cancer Therapy)

Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition)

edited by

Jinming Song

and

Ling Zhang

submission deadline 15 May 2026 | Viewed by 104 | Submission Open

Keywords: myeloproliferative neoplasm; chronic myeloid leukemia; polycythemia vera; essential thrombocythemia; primary myelofibrosis; MPN; CML; PMF; PV; ET

(This special issue belongs to the Section Molecular Cancer Biology)

Mass Spectrometry and Cancers

edited by

Rita Casadonte

and

Kristina Schwamborn

submission deadline 15 May 2026 | Viewed by 82 | Submission Open

Keywords: cancer; biomolecular; mass spectrometry

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Breast Cancer Screening: Global Practices and Future Directions

edited by Rudolf Morant

submission deadline 15 May 2026 | Viewed by 64 | Submission Open

Keywords: mammography screening; organized screening programs; tomosynthesis; 2D mammography; artificial intelligence; personalized screening

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Locoregional Therapies for Gastrointestinal Cancer Metastases

edited by

Mazin Al-Kasspooles

submission deadline 15 May 2026 | Viewed by 52 | Submission Open

Keywords: gastrointestinal cancer metastases; locoregional therapies; interventional radiology; endoscopy; radiation therapy; invasive operations; cytoreductive surgery (CRS); intraperitoneal chemotherapy (IP); heated intraperitoneal chemotherapy (HIPEC); tumor debulking; stereotactic body radiation therapy (SBRT); selective internal radiation therapy (SIRT)

(This special issue belongs to the Section Methods and Technologies Development)

The Surgical Management of Colorectal Cancer

edited by Gyung-mo Son

submission deadline 20 May 2026 | 9 articles | Viewed by 20741 | Submission Open

Keywords: colorectal cancer; surgical management; minimally invasive surgery; laparoscopic surgery; robotic surgery; single port surgery; emergency surgery; image-guided surgery; enhanced recovery after surgery (ERAS); systemic metastasis in colorectal cancer (involving the liver; lung; peritoneum; etc.)

(This special issue belongs to the Section Cancer Therapy)

How to Properly Diagnose and Treat Immune-Related Adverse Events During Immunotherapy in Patients with Cancer: Discussion Between Specialists (2nd Edition)

edited by

Angioletta Lasagna

and

Paolo Sacchi

submission deadline 20 May 2026 | Viewed by 61 | Submission Open

Keywords: ICIs; immune-related adverse effects (irAEs); infectious complications; immune reconstitution; inflammatory syndrome (IRIS); microbiota; vaccines; molecular mimicry

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Endometrial Cancer Prevention, Early Diagnosis and Treatment

edited by

Sarah J. Kitson

submission deadline 20 May 2026 | Viewed by 55 | Submission Open

Keywords: endometrial cancer; gynaecologic oncology; surgery; prevention; early diagnosis; advanced therapy; molecular classification; biomarkers

(This special issue belongs to the Section Cancer Therapy)

From Bench to Bedside: Novel Molecular Targets and Therapeutic Strategies in AML

edited by Matteo Molica

submission deadline 20 May 2026 | Viewed by 41 | Submission Open

Keywords: acute myeloid leukemia; targeted therapy; precision medicine; FLT3 inhibitors; IDH1/2 inhibitors; BCL2 inhibition; menin inhibitors; drug resistance; minimal residual disease; combination therapy

(This special issue belongs to the Section Cancer Therapy)

Advances in T-Cell Redirecting Therapy in Plasma Cell Neoplasms

edited by Henry Chi Hang Fung and Asya Varshavsky

submission deadline 20 May 2026 | Viewed by 28 | Submission Open

Keywords: multiple myeloma; CAR-T; T-cell engager; novel targets; sequencing

(This special issue belongs to the Section Cancer Therapy)

Viral Oncogenes and Their Role in Cancer Pathogenesis

edited by

Ronen Borenstein

and Yosef Sabo

submission deadline 21 May 2026 | 3 articles | Viewed by 5502 | Submission Open

Keywords: viral oncogenes; cancer pathogenesis; cellular regulation; tumorigenesis mechanisms; antiviral and anticancer strategies

(This special issue belongs to the Section Infectious Agents and Cancer)

Inhibitors in Thyroid Carcinoma (2nd Edition)

edited by

Alessandro Antonelli

submission deadline 24 May 2026 | Viewed by 107 | Submission Open

Keywords: thyroid carcinoma; immune checkpoint inhibitors; tyrosine kinase inhibitors; sorafenib; lenvatinib

(This special issue belongs to the Section Tumor Microenvironment)

Clinical Advances and State-of-the-Art Management in Genitourinary Cancers

edited by

Jad Chahoud

and Adnan Fazili

submission deadline 25 May 2026 | 2 articles | Viewed by 3428 | Submission Open

Keywords: genitourinary malignancies; tumor– immune microenvironment (TIME); tumor biology; genomic characterization; targeted drug therapy; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Colorectal Cancer: Risk Factors and Underlying Mechanisms

edited by David Achaintre

submission deadline 25 May 2026 | Viewed by 109 | Submission Open

Keywords: colorectal cancer; diet; environmental factors; microbiome; inflammation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Molecular Mechanisms of Breast Cancer Treatment-Related Side Effects and Precision Interventions

edited by

Jennifer Hu

submission deadline 26 May 2026 | Viewed by 76 | Submission Open

Keywords: breast cancer; treatment-related side effects; biomarker; precision interventions

(This special issue belongs to the Section Cancer Therapy)

Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies

edited by Nithya Ratnavelu and Ioannis Biliatis

submission deadline 28 May 2026 | 3 articles | Viewed by 2219 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

New Approaches in Radiotherapy for Cancer

edited by Dandan Zheng, Alexander Podgorsak and Olga Maria Dona Lemus

submission deadline 30 May 2026 | 21 articles | Viewed by 58238 | Submission Open

Keywords: adaptive radiotherapy; FLASH; artificial intelligence; SFRT; particle therapy; proton therapy; SRS; SBRT; HDR; 3D printing; immuno-radiotherapy; radiogenmics

(This special issue belongs to the Section Cancer Therapy)

AI-Driven Oncology: Advancing Cancer Detection, Diagnosis, and Personalized Treatment

edited by

Mohamed Shehata

and

Fatma M. Talaat

submission deadline 30 May 2026 | 2 articles | Viewed by 2166 | Submission Open

Keywords: cancer detection and diagnosis; AI in oncology; explainable AI (XAI); precision oncology; medical imaging; prognostic biomarkers; clinical decision support systems

(This special issue belongs to the Section Methods and Technologies Development)

Endoscopic Management of Pancreatic Neoplasms (2nd Edition)

edited by

Nam Quoc Nguyen

submission deadline 30 May 2026 | 1 articles | Viewed by 1785 | Submission Open

Keywords: pancreatic cancer; pancreatic neoplasm; endoscopic retrograde cholangiopancreatography; endoscopic ultrasound; fine needle aspiration/biopsy; local treatment; biliary stent; biliary drainage; contrast enhancement

(This special issue belongs to the Section Methods and Technologies Development)

Current Advances in Management of Neuroendocrine Neoplasms

edited by Ashley Kieran Clift and

Andrea Frilling

submission deadline 30 May 2026 | 1 articles | Viewed by 1160 | Submission Open

Keywords: neuroendocrine tumours; epidemiology; clinical prediction models; machine learning; personalised medicine; novel biomarkers; diagnostics; treatment; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Radiomics in Head and Neck Cancer Care (2nd Edition)

edited by

Aurora Mirabile

submission deadline 30 May 2026 | 1 articles | Viewed by 467 | Submission Open

Keywords: radiomics; personalized therapeutic approach; radiology; improving outcome; head and neck cancer; imaging biomarkers; artificial intelligence

(This special issue belongs to the Section Methods and Technologies Development)

Liquid Biopsy for Lung Cancer Treatment (2nd Edition)

edited by

Maria Palmieri

and Frullanti Elisa

submission deadline 30 May 2026 | Viewed by 247 | Submission Open

Keywords: cancer; lung cancer; new strategies; liquid biopsy; CTC; exosomes; Cf-NA; DdPCR; NGS

(This special issue belongs to the Section Cancer Biomarkers)

Genetics of Ovarian Cancer (2nd Edition)

edited by

Stergios Boussios

and

Sola Adeleke

submission deadline 30 May 2026 | Viewed by 136 | Submission Open

Keywords: epithelial ovarian cancer; genomics; epigenetics; translational research; biomarkers; DNA damage response; PARP inhibitors

(This special issue belongs to the Section Cancer Pathophysiology)

Updates on Depression Among Cancer Patients (2nd Edition)

edited by Wen-Yu Hu,

Yun-Chen Chang

and

Elsa Vitale

submission deadline 30 May 2026 | Viewed by 98 | Submission Open

Keywords: depression; psychotherapy; oncology nursing

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advances in the Diagnosis and Treatment of Prostate Cancer: From Biomarkers to Precision Surgery

edited by Stamatios N. Katsimperis and

Lazaros Tzelves

submission deadline 30 May 2026 | Viewed by 91 | Submission Open

Keywords: prostate cancer; precision medicine; molecular biomarkers; risk stratification; robotic surgery; artificial intelligence; genomics; personalized treatment; imaging modalities; multidisciplinary approach

(This special issue belongs to the Section Cancer Therapy)

Blood Stem Cell and Hematological Malignancies (Second Edition)

edited by Dirk Loeffler

submission deadline 30 May 2026 | Viewed by 51 | Submission Open

Keywords: hematopoietic stem cells; hematological malignancies; clonal hematopoiesis; clonal evolution; preleukemia and leukemia; self-renewal and differentiation; asymmetric cell division; cell polarity; therapy resistance; transformation

(This special issue belongs to the Section Molecular Cancer Biology)

Skin Cancer Prevention: Strategies, Challenges and Future Directions

edited by Véronique del Marmol, Mariano Suppa, Ana-Maria Forsea and Alexander Stratigos

submission deadline 30 May 2026 | Viewed by 33 | Submission Open

Keywords: skin cancer prevention; photoprotection; early detection; screening; epidemiology; public health; behavioral interventions; sun exposure; artificial intelligence; risk factors

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Health Services Research in Cancer Care

edited by

Francesco Giusti

and

Carmen Martos

submission deadline 31 May 2026 | 6 articles | Viewed by 12684 | Submission Open

Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Biomarkers—Detection and Evaluation of Response to Therapy

edited by

Giulio Francia

and

Jianying Zhang

submission deadline 31 May 2026 | 5 articles | Viewed by 7346 | Submission Open

Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies

(This special issue belongs to the Section Cancer Biomarkers)

Advances in Proton Therapy for Head and Neck Cancer: Techniques, Outcomes and Planning Variations

edited by Jun Zhou

submission deadline 31 May 2026 | 2 articles | Viewed by 5776 | Submission Open

Keywords: proton head and neck cancer therapy; protons vs. photons for head and neck cancer treatment; adaptive proton therapy; robustness in proton head and neck cancer therapy; online vs. offline adaptation in proton head and neck cancer therapy

(This special issue belongs to the Section Cancer Therapy)

Exploring the Interplay of Glioblastoma Angiogenesis, ROS, and Tumor Microenvironment: Advancements in Combination Therapy and Bioinformatics Approaches

edited by

Md Ataur Rahman

submission deadline 31 May 2026 | 1 articles | Viewed by 5301 | Submission Open

Keywords: glioblastoma; angiogenesis; reactive oxygen species (ROS); hypoxia-inducible factors (HIFs); radiotherapy (RT); bioactive natural compounds; tumor microenvironment (TME); cancer immunotherapy; combination therapy; autophagy; apoptosis; in silico and network pharmacology; bioinformatics

(This special issue belongs to the Section Cancer Metastasis)

Local Management of Breast Cancer: The Evolving Relationship Between Radiotherapy and Surgery

edited by Shengyang Peter Wu

submission deadline 31 May 2026 | 2 articles | Viewed by 5097 | Submission Open

Keywords: biomarker-guided personalized breast treatment; targeted axillary dissection; neoadjuvant therapy; local therapy; radiotherapy reduction; ultrahypofractionated partial breast irradiation

(This special issue belongs to the Section Cancer Therapy)

Developments in the Management of Gastrointestinal Malignancies (2nd Edition)

edited by Zachary J. Brown

submission deadline 31 May 2026 | 3 articles | Viewed by 4264 | Submission Open

Keywords: gastrointestinal malignancies; multimodal therapy; chemotherapy; radiotherapy; immunotherapy; localized and metastatic

(This special issue belongs to the Section Cancer Therapy)

Updates on Thyroid Cancer

edited by

Kwangsoon Kim

and

Ja Seong Bae

submission deadline 31 May 2026 | 3 articles | Viewed by 3906 | Submission Open

Keywords: thyroid cancer; surgery; updates; diagnosis; molecular biology; personalized medicine; artificial intelligence; novel therapeutic strategies; patient outcomes

(This special issue belongs to the Section Cancer Therapy)

Advances in Treatment of Uveal Melanoma

edited by

Bożena Romanowska-Dixon

and

Michał S. Nowak

submission deadline 31 May 2026 | 2 articles | Viewed by 3475 | Submission Open

Keywords: uveal melanoma; distant metastases; treatment modalities

(This special issue belongs to the Section Cancer Therapy)

Gut Microbiome, Diet and Cancer Risk

edited by

Byeongsang Oh

submission deadline 31 May 2026 | 3 articles | Viewed by 2862 | Submission Open

Keywords: gut microbiome; cancer; diet; dysbiosis; immunity; dietary fiber; probiotic; short-chain fatty acids (SCFAs)

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Prostate Cancer and Inflammation

edited by Takuji Hayashi

submission deadline 31 May 2026 | 1 articles | Viewed by 2107 | Submission Open

Keywords: prostate cancer; inflammation; immune cells; cytokine; chemokine; anti-inflammatory agents; diet; microbiome

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Focus on Focal Therapy for Prostate Cancer

edited by Abhinav Sidana and Samuel Tremblay

submission deadline 31 May 2026 | 1 articles | Viewed by 1655 | Submission Open

Keywords: focal therapy; prostate cancer treatment; image-guided therapy; oncological outcomes; functional outcome; patient selection; surveillance

(This special issue belongs to the Section Cancer Therapy)

The Role of Circulating Tumor Cells in Colorectal Cancer

edited by

Chiara Nicolazzo

submission deadline 31 May 2026 | 1 articles | Viewed by 1538 | Submission Open

Keywords: circulating tumor cells (CTC); colorectal cancer (CRC); liquid biopsy; biomarkers; tumor progression; personalized medicine; molecular profiling; metastasis; diagnostic techniques; prognostic evaluation

(This special issue belongs to the Section Cancer Biomarkers)

MicroRNA in Cancer: From Molecular Mechanisms to Therapeutic Applications

edited by Girish Shukla and

Sivakumar Vijayaraghavalu

submission deadline 31 May 2026 | 2 articles | Viewed by 1526 | Submission Open

Keywords: microRNA (miRNA) therapeutics; cancer biomarkers; oncogenic and tumor-suppressive miRNAs; miRNA delivery systems; precision oncology

(This special issue belongs to the Section Cancer Biomarkers)

Survivorship and Quality of Life in Endometrial Cancer

edited by George Koukourakis,

Antonios Anagnostopoulos

, Georgios Angelopoulos and Anthi Miliadou

submission deadline 31 May 2026 | 1 articles | Viewed by 685 | Submission Open

Keywords: endometrial cancer; quality of life; survivorship

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Nano-Targeting of Cancer

edited by Thomas Ming Swi Chang OC MD CM PhD DSc FRCPC FRSC FCAHS

submission deadline 31 May 2026 | 1 articles | Viewed by 626 | Submission Open

Keywords: drug delivery; artificial intelligence; targeted delivery; nanorobotics; prodrug activation; intracellular action; liposome; PEGylation; nanoparticles; nanocapsules; nanoartificial cells

(This special issue belongs to the Section Cancer Therapy)

Clinical and Translational Research of Urological Cancer

edited by

Mauro Ragonese

and

Luca Di Gianfrancesco

submission deadline 31 May 2026 | 1 articles | Viewed by 482 | Submission Open

Keywords: urological cancer; bladder cancer; surgery; conservative treatment; immunotherapy; radical cystectomy; artifical intelligence

(This special issue belongs to the Section Clinical Research of Cancer)

Primary Central Nervous System Lymphoma: A Challenging Disease

edited by

Roser Velasco

submission deadline 31 May 2026 | Viewed by 369 | Submission Open

Keywords: primary central nervous system lymphoma (PCNSL); diffuse large B cell lymphoma (DLBCL); advanced imaging; novel therapies; prognostic markers

(This special issue belongs to the Section Clinical Research of Cancer)

Displaying special issue 801-850 on page 17 of 24.

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