Particle Therapy: State-of-the-Art and Future Prospects

Dear Colleagues,

Although particle therapy is, at present, perceived as a not sufficiently utilized in radiation-therapy facilities worldwide, we have witnessed its rapid development in recent decades, and it is believed that its impact will be more substantial when the technology and clinical practices are optimized. Exciting technical advances have been reported recently, including ultra-high dose rates, biological optimizations, proton arcs, multi-ion therapy, superconducting gantry, improvements in beam-delivery efficiency, uncertainty reduction, and MR-guided proton therapy. On the other hand, the medical community eagerly awaits the data that demonstrate the clinical benefits of using particle therapy. This Topical Collection is devoted to the worldwide efforts in developing, improving, and using the most complex radiotherapy modality.

We invite submissions of articles that address the following topics:

• Technical advances in proton and ion therapies;
• Clinical evidence in particle therapy;
• Clinical indications of particle therapy;
• Controversies in particle therapy;
• Novel applications of particle therapy to treat cancer and noncancerous tumors;
• Predictive outcome modeling for patients receiving particle therapy;
• Imaging for particle therapy—image guidance, uncertainty reduction, adaptive therapy, treatment effects.

Dr. Chia-Ho Hua
Dr. Matthew J. Krasin
Collection Editors

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