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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Eye-Tracking Monitoring of Neurological and Psychiatric Conditions Across Life Span

edited by

Marco Cavallo

and

Juan Esteban Kamienkowski

submission deadline 23 Feb 2026 | 3 articles | Viewed by 5561 | Submission Open

Keywords: gaze patterns; eye tracking; mild cognitive impairment; multiple sclerosis; neurodevelopmental disorders; saccades

(This special issue belongs to the Section Behavioral Neuroscience)

Current Advances in Developmental Dyslexia

edited by

John F. Stein

submission deadline 25 Feb 2026 | Viewed by 132 | Submission Open

Keywords: developmental dyslexia; neuroimaging; neuropsychology; molecular genetics

(This special issue belongs to the Section Neurolinguistics)

Advances in Pediatric Neurological Disease Research

edited by Milena La Spina and

Silvia Marino

submission deadline 25 Feb 2026 | Viewed by 85 | Submission Open

Keywords: non-invasive ventilation; ultrasound; epilepsy; CNS infection; neuro-oncology; genetic disease; sindromology; polysomnography

(This special issue belongs to the Section Developmental Neuroscience)

Prenatal and Perinatal Risk Factors for Autism

edited by Gary Steinman

submission deadline 25 Feb 2026 | Viewed by 59 | Submission Open

Keywords: perinatal period; prenatal infection; children born preterm; pregnancy; autism

(This special issue belongs to the Section Developmental Neuroscience)

Lucid Dreaming and Psychophysiological Correlates of States of Consciousness

edited by

Daniel Erlacher

and Clarita Bonamino

submission deadline 27 Feb 2026 | 1 articles | Viewed by 888 | Submission Open

Keywords: lucid dreaming; states of consciousness; REM sleep; metacognition; dream phenomenology; volitional control

(This special issue belongs to the Section Neuropsychology)

Mental Images and the Brain: From Cognitive Neuropsychology to Functional Neuroimaging

edited by

Anna Maria Berardi

submission deadline 27 Feb 2026 | Viewed by 65 | Submission Open

Keywords: mental imagery; visual perception; dorsal visual stream; ventral visual stream; object; spatial; brain lesion; functional brain imaging; aphantasia; hyperphantasia

(This special issue belongs to the Section Neuropsychology)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3327 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2663 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Assessment and Training of Perceptual-Motor Performance (2nd Edition)

edited by

Gary Wilkerson

and

Scott L. Bruce

submission deadline 28 Feb 2026 | 1 articles | Viewed by 689 | Submission Open

Keywords: perception; cognition; motor control; neural efficiency; traumatic brain injury; neurodegeneration; psycho-affective disorder

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 28 Feb 2026 | Viewed by 237 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Non-Invasive Brain Stimulation for Brain Disorders

edited by

Giovanni Cirillo

submission deadline 28 Feb 2026 | Viewed by 105 | Submission Open

Keywords: TMS; tCS; NIBS; plasticity; CNS; neurological disorders; psychiatric disorders

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Novel Techniques in Spine Neurosurgery

edited by Maurizio Fornari,

Cesare Faldini

and Gabriele Capo

submission deadline 28 Feb 2026 | Viewed by 105 | Submission Open

Keywords: spine neurosurgery; minimally invasive spine surgery; spinal endoscopy; robotic-assisted spine surgery; spinal navigation; augmented reality in neurosurgery; biologics and spinal fusion; neuromodulation; novel surgical techniques; technological innovation in spine surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Cellular and Molecular Mechanisms Underlying Aging Progression

edited by

Mateus Vidigal de Castro

submission deadline 28 Feb 2026 | Viewed by 72 | Submission Open

Keywords: neuroaging ; neurodegeneration ; iPSC-derived models ; omics technologies ; cellular senescence ; neuroinflammation ; longevity

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Advances in Neuroinflammation and Immune Response

edited by Bojan Shutinoski

submission deadline 28 Feb 2026 | Viewed by 62 | Submission Open

Keywords: neuroinflammation; immune response; glial cells; blood– brain barrier; neurodegenerative diseases

(This special issue belongs to the Section Systems Neuroscience)

Anxiety and Mood Disorders: Novel Research on Mechanisms, Diagnosis, and Treatment

edited by

Zuleide Maria Ignácio

submission deadline 28 Feb 2026 | Viewed by 48 | Submission Open

Keywords: anxiety disorders; mood disorders; neurotransmission; genetic and epigenetic mechanisms; therapeutic strategies; pharmacological targets; cellular circuits and signaling; neuronal plasticity; inflammation; oxidative stress

(This special issue belongs to the Section Neuropsychiatry)

Risks and Mechanisms in Addiction Neuroscience Informing Treatment

edited by Amy A. Herrold

submission deadline 7 Mar 2026 | Viewed by 200 | Submission Open

Keywords: substance use disorders; risk; mechanism; neuromodulation; psychedelic; GLP-1

(This special issue belongs to the Section Neuropsychiatry)

Application of Invasive and Non-Invasive Brain Stimulation Techniques in Neurological Disorders

edited by Vincenzo Levi and

Massimo Marano

submission deadline 10 Mar 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: deep brain stimulation (DBS); magnetic resonance-guided focused ultrasound (MRgFUS); transcranial magnetic stimulation (TMS); transcranial direct-current stimulation (tDCS); vagus nerve stimulation (VNS); brain– machine interface; brain stimulation; non-invasive brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Current Basic and Clinical Approaches in Neurodegenerative Diseases: Diagnostics and Therapeutics

edited by

Genaro G. Ortiz

and Gloria A. Benítez-King

submission deadline 15 Mar 2026 | 3 articles | Viewed by 9930 | Submission Open

Keywords: neurodegenerative diseases; advances; diagnosis; treatment; basic clinical approach; treatment protocols

(This special issue belongs to the Section Neurodegenerative Diseases)

Unraveling the Role of Physical Activity in Brain, Cognition, and Mental Health

edited by

Fiorenzo Moscatelli

, Nicola Mancini and Pompilio Cusano

submission deadline 15 Mar 2026 | 3 articles | Viewed by 4123 | Submission Open

Keywords: physical activity; brain health; cognition; mental health; neurogenesis; neuroplasticity; cognitive function; exercise; depression; anxiety

(This special issue belongs to the Section Neuropsychiatry)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1688 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Neuropeptides, Behavior and Psychiatric Disorders

edited by Chanpreet Singh and Jin Xu

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1286 | Submission Open

Keywords: neuropeptides; psychiatric disorders; behavioral neuroscience; neuromodulation; stress and emotion; neurocircuitry; translational psychiatry; biomarkers; optogenetics; peptidergic signaling

(This special issue belongs to the Section Behavioral Neuroscience)

Spinal Cord Injury: Biomarkers, Neuroimaging and Therapeutic Approaches

edited by

Alaa Abd-Elsayed

submission deadline 15 Mar 2026 | 1 articles | Viewed by 316 | Submission Open

Keywords: spinal cord; injury; neuromodulation; surgery; injury; innovations

(This special issue belongs to the Section Neurorehabilitation)

EEG and fMRI Applications in Exploring Brain Activity

edited by

Nicoletta Cera

and Faustino Ricardo

submission deadline 15 Mar 2026 | Viewed by 179 | Submission Open

Keywords: fMRI; EEG; resting state; data-driven analysis; machine learning; emotion; cognitive functions; aging; multimodal imaging

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Concussions

edited by

Neil Heron

submission deadline 15 Mar 2026 | Viewed by 27 | Submission Open

Keywords: concussion; mild traumatic brain injury; systematic review; concussion biomarkers; clinical trials; public health

(This special issue belongs to the Section Systems Neuroscience)

Neuromorphic Artificial Intelligence and Its Applications: Retrospective and Prospective

edited by Vassilis Cutsuridis

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2139 | Submission Open

Keywords: neuromorphic artificial intelligence; deep learning; sensory recognition; cognitive function; cognitive robotics; neuroimaging

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

The Olfactory System in Health and Disease

edited by David M. Coppola

submission deadline 20 Mar 2026 | 1 articles | Viewed by 709 | Submission Open

Keywords: Alzheimer’ s; Parkinson’ s; Huntington’ s; MS; depression; anxiety; disorder; olfactory bulbectomy; anosmia; smell; limbic system

(This special issue belongs to the Section Systems Neuroscience)

Clinical Research on Neurological Rehabilitation After Stroke

edited by

Myoung-Kwon Kim

submission deadline 20 Mar 2026 | 1 articles | Viewed by 86 | Submission Open

Keywords: stroke rehabilitation; neurological recovery; physical therapy; cognitive rehabilitation; neuroplasticity; functional outcomes; assistive technology; virtual reality therapy; Parkinson’ s disease rehabilitation

(This special issue belongs to the Section Neurorehabilitation)

The Role of Multimodal Imaging in Assessing the Biology and Staging of Neurodegenerative Disorders

edited by

Andrea Varrone

submission deadline 20 Mar 2026 | Viewed by 72 | Submission Open

Keywords: amyloid beta; phosphorylated tau; alpha-synuclein; neuronal loss; neuromelanin; iron content; cardiac denervation; dopaminergic cell loss

(This special issue belongs to the Section Neurodegenerative Diseases)

Cellular and Molecular Mechanisms of Neuropathic Pain

edited by

Al-Khrasani Mahmoud

submission deadline 20 Mar 2026 | Viewed by 55 | Submission Open

Keywords: neuropathic pain; mechanisms; novel targets; natural drugs; novel synthetic and semi-synthetic drugs; monoclonal antibodies

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Rehabilitation Strategies for Traumatic Brain Injury

edited by

Jennifer V. Wethe

submission deadline 20 Mar 2026 | Viewed by 47 | Submission Open

Keywords: traumatic brain injury; neurorehabilitation; neuroplasticity; cognitive rehabilitation; virtual reality; community reintegration; tele-rehabilitation; neurostimulation; translational research; individualized intervention

(This special issue belongs to the Section Neurorehabilitation)

Inflammation, Stress, and Comorbidity in Psychiatry: Mechanisms and Therapeutic Implications

edited by Heline Mirzakhanian

submission deadline 20 Mar 2026 | Viewed by 35 | Submission Open

Keywords: immune biomarkers in psychiatry; neuroinflammation; precision neuropsychiatry; risk mechanisms; comorbidity models; HPA axis dysregulation; anti-inflammatory treatments; psychiatric and physical comorbidity; cytokine signaling; microglial activation

(This special issue belongs to the Section Neuropsychiatry)

Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 31 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Neurobehavioral Mechanisms of Learning and Adaptation: Translational Perspectives from Basic to Applied Science

edited by John Michael Falligant and

Rusty Nall

submission deadline 20 Mar 2026 | Viewed by 26 | Submission Open

Keywords: behavioral neuroscience; experimental analysis of behavior; computational behavior analysis; quantitative modeling; reinforcement learning; translational research; behavioral pharmacology; neurobehavioral mechanisms of learning; persistence and relapse; behavioral phenotyping

(This special issue belongs to the Section Behavioral Neuroscience)

Balance: Multisensory Integration and Rehabilitation Approaches

edited by

Min-wook Kim

submission deadline 25 Mar 2026 | Viewed by 67 | Submission Open

Keywords: multisensory integration; balance and gait disorders; vestibular; visual; and somatosensory assessment; postural control; sensorimotor dysfunction; neurodegenerative diseases (e.g.; Parkinson’ s; PSP); stroke and brain injury; motor rehabilitation; virtual and augmented reality; neuroplasticity; fall risk and prevention; wearable technology and kinematic analysis

(This special issue belongs to the Section Neurodegenerative Diseases)

Neural Correlates of Cognitive Workload and Learning: Portable Brain Monitoring During Skill Acquisition and Real-World Task Performance

edited by Adrian Curtin, Sebastien Scannella,

Hasan Ayaz

and

Candida Barreto

submission deadline 25 Mar 2026 | Viewed by 61 | Submission Open

Keywords: portable neuroimaging; wearable brain sensing; skill acquisition; expertise development; motor learning; cognitive workload; fNIRS/EEG applications; neural efficiency; closed-loop training; neurostimulation (tDCS/rTMS/FUS)

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Language Perception and Processing

edited by

Ratree Wayland

submission deadline 27 Mar 2026 | 4 articles | Viewed by 2370 | Submission Open

Keywords: language; cognitive mechanism; neural mechanism; speech; perception; processing

(This special issue belongs to the Section Neurolinguistics)

Palliative Care for Patients with Severe Neurological Impairment

edited by

Giovanna Artioli

and

Federica Dellafiore

submission deadline 30 Mar 2026 | 2 articles | Viewed by 2289 | Submission Open

Keywords: severe neurological impairment; neurological chronic disease; palliative care; early palliative care; nursing competencies; advance care planning; caregiver support; mental Illness of Healthcare professionals; non pharmacological and complementary treatment; bio-psyco-social and existential needs of patient and caregiver

(This special issue belongs to the Section Neurorehabilitation)

Advances in LRRK2 and Other Pathological Mechanisms of Parkinson's Disease

edited by

Dong Hwan Ho

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1983 | Submission Open

Keywords: Parkinson's disease; leucine-rich repeat kinase 2; dopaminergic neuronal death; neurodegenerative disease; neuroinflammation; neuroprotection

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Research Progress on the Pathogenesis, Diagnosis and Treatment of Parkinson Disease

edited by Giulia Carli and Prabesh Kanel

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1135 | Submission Open

Keywords: Parkinson’ s disease; Lewy bodies diseases; disease progression; clinical heterogeneity; preclinical and prodromal stages; treatments; comorbidities

(This special issue belongs to the Section Neurodegenerative Diseases)

Burnout, Adjustment Disorder and Post-Traumatic Stress Disorder: Risk Factors, Impact, Preventive Strategies and Treatment Options

edited by

Martina Corsi

and

Rudy Foddis

submission deadline 31 Mar 2026 | 1 articles | Viewed by 815 | Submission Open

Keywords: burnout; AD; PTSD; psychosocial risk; AI; prevention; diagnosis; treatment

(This special issue belongs to the Section Systems Neuroscience)

Editorial Board Collection Series: Innovative Research in Molecular and Cellular Neuroscience for Regulation of Cell Death Mechanisms for Functional Neuroprotection

edited by

Swapan K. Ray

submission deadline 31 Mar 2026 | 1 articles | Viewed by 689 | Submission Open

Keywords: apoptosis; autophagy; artificial intelligence; CRISPR; demyelination; ferroptosis; inflammasomes; microRNAs; necrosis; neuroprotection; organoids; PANoptosis; animal and cellular models of neurological diseases and injuries; proteases

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Plasticity of Sensory Cortices: From Basic to Clinical Research

edited by Stephanie Clarke and Sonia Crottaz-Herbette

submission deadline 31 Mar 2026 | Viewed by 124 | Submission Open

Keywords: tonotopy; retinotopy; somatotopy; vestibular; olfactory; gustatory; training-induced plasticity; postlesional plasticity; cochlear implant; prostheses

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Emerging Trends and Perspectives in the Neuroscience of Pain

edited by Martina Rekatsina and

Panagiotis Zis

submission deadline 31 Mar 2026 | Viewed by 76 | Submission Open

Keywords: neuroscience of pain; neuroimaging techniques; neuromodulation therapies; pain mechanisms; chronic pain

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Dementia and Cognitive Decline in Aging

edited by

Yvonne Leung

submission deadline 31 Mar 2026 | Viewed by 75 | Submission Open

Keywords: dementia; cognitive impairment; Alzheimer’ s disease; mild cognitive impairment (MCI); neurodegeneration; cognitive aging; biomarkers; cognitive resilience; cognitive reserve

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Shaping the Brain in Sleep: Neurodevelopmental Mechanisms Across the Lifespan

edited by Sally Staton, Jasneek Chawla and Kartik Iyer

submission deadline 31 Mar 2026 | Viewed by 72 | Submission Open

Keywords: sleep; brain development; neurodevelopment; sensitive periods; napping; genetic and environmental influences; early childhood; adolescents; adulthood; lifespan development

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neuroimmune Crosstalk in Neurological Disorders: Mechanistic Insights to Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 31 Mar 2026 | Viewed by 44 | Submission Open

Keywords: neuroinflammation; neuroimmune system; glial cell dynamics; immune cell trafficking; cyto-kine signaling; neurological disorders; immune modulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Stress and Trauma Revisited: Oxytocin, Sociostasis, and Hormesis—Missing Pieces of an Evolving Puzzle

edited by C. Sue Carter, Marcy Kingsbury and Hans Nazarloo

submission deadline 31 Mar 2026 | Viewed by 37 | Submission Open

Keywords: oxytocin; vasopressin; stress; sociostasis; hormesis

(This special issue belongs to the Section Systems Neuroscience)

Psychiatry and Addiction: A Multi-Faceted Issue—2nd Edition

edited by

Fabrizio Schifano

Norbert Scherbaum

and

Giovanni Martinotti

submission deadline 31 Mar 2026 | Viewed by 36 | Submission Open

Keywords: addiction spectrum disorders; substance misuse; dual disorders; alcohol misuse; prescription drug misuse; dopamine; neurotransmitter pathways; reward systems; addiction treatment; reward deficit syndrome; translational anti-craving medications; food addiction; sex addiction; internet gaming disorder; gambling; novel antidiabetics; salience; novel psychoactive substances (NPSs); prescription drug misuse; brain– gut axis; microbiome

(This special issue belongs to the Section Behavioral Neuroscience)

Advances in Immune-Mediated Disorders of the Nervous System in Childhood

edited by Martino Ruggieri and

Andrea Domenico Praticò

submission deadline 10 Apr 2026 | Viewed by 109 | Submission Open

Keywords: autoimmune encephalitis; pediatric neuroinflammation; immune-mediated CNS disorders; childhood multiple sclerosis; MOG antibody disease; neuroimmunology; immunotherapy in children; neuromyelitis optica

(This special issue belongs to the Section Developmental Neuroscience)

New Perspectives on Language Processing in Aging

edited by Andrea Marini

submission deadline 15 Apr 2026 | Viewed by 144 | Submission Open

Keywords: aging; language; cognition; phonology; lexical skills; grammatical skills; pragmatics; discourse; neuropsychology of language

(This special issue belongs to the Section Neurolinguistics)

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