Advances in Borderline Personality Disorder: From Detection to Treatment

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropsychiatry".

Deadline for manuscript submissions: 9 October 2026

Special Issue Editor


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Guest Editor
Centro Psicologia Dinamica, Universitas Mercatorum, 00186 Rome, Italy
Interests: affective neuroscience; emotion regulation; psychotherapy; psychopathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Borderline Personality Disorder (BPD) is a complex and multifaceted condition characterized by instability in emotions, self-image, and interpersonal relationships. Despite advances in research and clinical practice, early detection and effective treatment remain major challenges. Understanding the underlying mechanisms, improving diagnostic accuracy, and developing evidence-based interventions are critical steps toward enhancing outcomes for individuals affected by BPD.

This Special Issue seeks high-quality contributions that advance knowledge across the spectrum of BPD research and care. We welcome original research, reviews, and theoretical articles that explore topics such as the following:

  • Innovative approaches to early detection and risk identification;
  • Advances in psychotherapeutic and pharmacological treatment strategies;
  • Mechanisms underlying emotional dysregulation, impulsivity, and interpersonal difficulties;
  • Longitudinal studies and predictors of treatment response;
  • Integrated models of care and recovery-oriented interventions;
  • Neurobiological and genetic insights into BPD;
  • Digital health tools and technology-assisted interventions;
  • Comorbidities and differential diagnosis in BPD;
  • Cultural, social, and environmental factors influencing BPD presentation and outcomes.

We encourage submissions that combine scientific rigor with clinical relevance, aiming to bridge the gap between research and practice. Contributions highlighting new insights, novel methodologies, or translational applications that can inform patient-centred care are particularly welcome.

By gathering cutting-edge work in a single issue, our goal is to foster a deeper understanding of BPD and promote strategies that improve detection, treatment, and overall quality of life for those affected. We invite researchers, clinicians, and scholars from diverse disciplines to contribute to this timely and important collection.

Dr. Irene Messina
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • borderline personality disorder
  • early detection
  • treatment
  • mechanisms
  • neurobiology

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Published Papers

This special issue is now open for submission.
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