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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Locus Coeruleus Function and Vulnerability in Neurodegenerative Conditions: Evidence from Animal Model and Human Imaging Studies

edited by

Oxana Eschenko

and Dorothea Hämmerer

submission deadline 15 Sep 2025 | Viewed by 355 | Submission Open

Keywords: noradrenaline; locus coeruleus; neuromodulation; magnetic resonance imaging; neurodegeneration; psychiatric disorders; sleep; brainstem

(This special issue belongs to the Section Systems Neuroscience)

Traumatic Stress and Dissociative Disorder

edited by Federica Visco-Comandini

submission deadline 19 Sep 2025 | 2 articles | Viewed by 6346 | Submission Open

Keywords: PTSD; dissociation; C-PTSD; trauma exposure; interpersonal violence; abuse; relational trauma; childhood abuse

(This special issue belongs to the Section Neuropsychiatry)

Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia

edited by Chiara Baglioni and Debora Meneo

submission deadline 20 Sep 2025 | Viewed by 148 | Submission Open

Keywords: sleep health; insomnia; emotional processes; pre-sleep behaviours; cognitive processes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Unraveling Autism: Neurobiological Mechanisms and Emerging Therapeutic Advances

edited by Antonio Nicotera and

Gabriella Di Rosa

submission deadline 25 Sep 2025 | 2 articles | Viewed by 3738 | Submission Open

Keywords: autism; neurobiology; autistic spectrum disorder; neurodevelopment; genetic

(This special issue belongs to the Section Developmental Neuroscience)

Understanding the Functioning of Brain Networks in Health and Disease

edited by

Moses O. Sokunbi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1456 | Submission Open

Keywords: brain networks; cognitive dysfunction; diffusion tensor imaging (DTI); electroencephalography (EEG); functional connectivity; functional magnetic resonance imaging (fMRI); magnetoencephalography (MEG); neurological disorders; neuroplasticity; psychiatric disorders; artificial intelligence; deep learning; neural networks; signal complexity

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Brain Development—Shedding Light on Opioid Exposure and Health Disparities

edited by

Adam Abba-Aji

submission deadline 25 Sep 2025 | 1 articles | Viewed by 411 | Submission Open

Keywords: opioids; brain development; cognition; quality of life

(This special issue belongs to the Section Developmental Neuroscience)

Molecular Insights in Neurodegeneration

edited by

Oscar Arias-Carrión

submission deadline 25 Sep 2025 | Viewed by 126 | Submission Open

Keywords: neurodegeneration; molecular mechanisms; protein aggregation; neuroinflammation; oxidative stress; mitochondrial dysfunction; Alzheimer& rsquo; s disease; Parkinson& rsquo; s disease; biomarkers; therapeutic targets

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Exploration of Cerebrovascular Diseases: From Preclinical Research to Treatment

edited by

Basil Grüter

and

Martina Sebök

submission deadline 26 Sep 2025 | 15 articles | Viewed by 20481 | Submission Open

Keywords: intracranial aneurysm; arterio-venous malformation (AVM); dural arterio-venous fistula (AVF); ischaemic stroke; chronic steno-occlusive disease

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Recent Advances in Neurorehabilitation: Emerging Techniques and Technologies

edited by

Serena Dattola

and

Lilla Bonanno

submission deadline 26 Sep 2025 | 8 articles | Viewed by 12391 | Submission Open

Keywords: neurorehabilitation; neuroimaging; robotic rehabilitation; virtual reality therapy; neuroprosthetics; brain– computer interfaces; pharmacological interventions; functional recovery; neuroplasticity; cognitive rehabilitation

(This special issue belongs to the Section Neurorehabilitation)

Focus on Mental Health and Mental Illness in Adolescents

edited by

Dariusz Krok

submission deadline 30 Sep 2025 | 7 articles | Viewed by 32927 | Submission Open

Keywords: mental health; mental illness; adolescents; coping with stress; psychotherapy; medical treatment; well-being

(This special issue belongs to the Section Neuropsychiatry)

New Insights into Movement Generation: Sensorimotor Processes

edited by

Koichi Hiraoka

submission deadline 30 Sep 2025 | 8 articles | Viewed by 14653 | Submission Open

Keywords: motor plan; somatosensation; sensory– motor integration; feedback; vision; motor execution; movement; motor control; stimulus– response mapping

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Editorial Board Collection Series: Insight into Neurosurgery

edited by

Massimiliano Visocchi

and

Francesco Signorelli

submission deadline 30 Sep 2025 | 5 articles | Viewed by 6670 | Submission Open

Keywords: brain; skull base; craniocervical junction; spine and spinal cord; demolition reconstruction

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Language Dysfunction in Posterior Cortical Atrophy

edited by

Deepti Putcha

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1991 | Submission Open

Keywords: Alzheimer’ s disease; atypical AD; visual variant; posterior cortical atrophy; reading; spelling; writing; visual; visuospatial

(This special issue belongs to the Section Neurodegenerative Diseases)

The Perils of Social Media Addiction

edited by Mike Zhengyu Yao

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1139 | Submission Open

Keywords: social media addiction; digital dependency; internet addiction; device dependency; mental health and technology; mental health interventions; digital well-being

(This special issue belongs to the Section Neuropsychiatry)

Contemporary Spinal Surgery: Surgical Optimization and Technological Innovation

edited by

Nicola Montemurro

and Francesco Acerbi

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1003 | Submission Open

Keywords: minimally invasive techniques; telehealth; spinal vascular malformation; spinal tumor; 3D printing; surgical planning; artificial intelligence; endoscopy in spine surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Understanding the Role and Functions of the Insula in the Brain

edited by

Boucher Olivier

and

Dang Khoa Nguyen

submission deadline 30 Sep 2025 | 1 articles | Viewed by 777 | Submission Open

Keywords: insula; neuropsychology; disorder; pathology; cognition; emotion; addiction; neurostimulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Advances in Face Perception and How Disorders Affect Face Perception

edited by Karen Lander, Rachel Bennetts and Natalie Butcher

submission deadline 30 Sep 2025 | Viewed by 432 | Submission Open

Keywords: face perception; face recognition; prosopagnosia; neurodevelopmental disorders; individual differences; clinical disorders

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Innovation on Neuropsychological and Cognitive Changes in Aging: Assessment and Intervention

edited by Renata Kochhann, Laiss Bertola and

Bernardino Fernández-Calvo

submission deadline 30 Sep 2025 | Viewed by 245 | Submission Open

Keywords: aging; dementia; neuropsychology; neuropsychological test; non-pharmacological interventions

(This special issue belongs to the Section Neuropsychology)

From Neurodevelopment to Mental Health: New Insight on Psychiatric Disorders Among Children, Adolescents and Young Adults

edited by

Maria Giuseppina Petruzzelli

Emilia Matera

and Alessandra Gabellone

submission deadline 30 Sep 2025 | Viewed by 181 | Submission Open

Keywords: childhood; adolescence; neurodevelopment; psychopathological onset; mental health; developmental trajectory; neurobiology; early interventions; clinical overlap; environmental risk factors; diagnostic process

(This special issue belongs to the Section Neuropsychiatry)

Advances and Perspectives in Stereotactic Neurosurgery and Radiosurgery

edited by

Michele Longhi

and Antonio Nicolato

submission deadline 30 Sep 2025 | Viewed by 168 | Submission Open

Keywords: gamma knife; radiosurgery; focused ultrasound; stereotactic neurosurgery; DBS

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Nanomedicine in Neurological Disorders

edited by

Mariana Matias

and

Márcio Rodrigues

submission deadline 30 Sep 2025 | Viewed by 165 | Submission Open

Keywords: neurological disorders; neuropharmacology; preclinical studies; efficacy and safety assessment; nanomedicines; nanotechnology; brain

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Development of Prosociality: From Philosophy to Neuroscience

edited by Bahia Guellaï and

Mayilin Moreno

submission deadline 30 Sep 2025 | Viewed by 130 | Submission Open

Keywords: prosociality; development; interdisciplinarity; social neurosciences

(This special issue belongs to the Section Developmental Neuroscience)

Biomarker Development in the Early Identification of Autism Spectrum Disorders

edited by Elissar Andari

submission deadline 30 Sep 2025 | Viewed by 127 | Submission Open

Keywords: autism deep phenotyping; social and affective neuroscience; biomarkers

(This special issue belongs to the Section Developmental Neuroscience)

Advances in Psychosocial and Neurological Aspects in Supportive Cancer Care

edited by

Philip R. Debruyne

Patricia Schofield

and

Laura Tack

submission deadline 30 Sep 2025 | Viewed by 88 | Submission Open

Keywords: supportive cancer care; neuropsychology; psychosocial; quality of life; pain management

(This special issue belongs to the Section Neuropsychology)

From Satiety to Psychiatry: Exploring the Role of GLP-1 Receptor Agonists in Mental Health, Substance Use and Neuropsychiatric Disorders

edited by

Davide Arillotta

Giuseppe Floresta

and

Fabrizio Schifano

submission deadline 3 Oct 2025 | 1 articles | Viewed by 2400 | Submission Open

Keywords: GLP-1 receptor agonists (GLP-1 RAs); dual GIP/GLP-1 agonists; reward; craving; behavioral addictions; mental health; psychiatry; substance use disorders; semaglutide; tirzepatide

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Retina, Visual Function and Circadian Involvement in Parkinson’s Disease

edited by Gregory L. Willis

submission deadline 10 Oct 2025 | Viewed by 185 | Submission Open

Keywords: Parkinson’ s disease; retina; circadian; dopamine; melatonin; prodromal; vision

(This special issue belongs to the Section Neurodegenerative Diseases)

Research on Cannabis and Other Substance Abuse: Neurological Insights

edited by Patricia Di Ciano

submission deadline 10 Oct 2025 | Viewed by 170 | Submission Open

Keywords: cannabis; cocaine; opioids; amphetamine; tobacco; brain imaging; driving; cognition; diagnosis; treatment; harm reduction; legalization

(This special issue belongs to the Section Behavioral Neuroscience)

Noninvasive Neuromodulation Applications in Research and Clinics

edited by

Mehran Emadi Andani

and Fatemeh B. Yavari

submission deadline 15 Oct 2025 | 2 articles | Viewed by 5381 | Submission Open

Keywords: transcranial brain stimulation (TBS); transcranial magnetic stimulation (TMS; rTMS; iTBS; and cTBS); transcranial electrical stimulation (tDCS; tACS; and tRNS); transcranial focused ultrasound stimulation (tFUS); transcranial vagus nerve stimulation (tVNS); virtual reality effect on the brain states; TBS applications in neuromotor disease (Parkinson’ s disease and Huntington’ s disease); TBS applications in mental disease (Alzheimer disease and Dementia); TBS application on functional brain mapping (TMS brain mapping); clinical application of brain stimulation in motor symptoms in PD patients (tremor; gait; bradykinesia; postural instability; rigidity; handwriting; etc.); clinical application of brain stimulation in non-motor symptoms (cognitive; psychosis; neuropsychiatric; etc.); safety of brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 15 Oct 2025 | 3 articles | Viewed by 5359 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Digital Mental Health

edited by

Oana Alexandra David

submission deadline 15 Oct 2025 | Viewed by 180 | Submission Open

Keywords: digital mental health; therapeutic apps; game-based psychotherapy; online CBT; virtual reality therapy

(This special issue belongs to the Section Behavioral Neuroscience)

New Horizons in Dystonia Research

edited by Nicoletta Manzo

submission deadline 15 Oct 2025 | Viewed by 114 | Submission Open

Keywords: dystonia; neurophysiology; movement disorders; brain stimulation; botulinum toxin injection

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Innovations in Pediatric Functional Neurosurgery

edited by Samuel Tomlinson and Benjamin C. Kennedy

submission deadline 15 Oct 2025 | Viewed by 56 | Submission Open

Keywords: pediatric neurosurgery; functional neurosurgery; epilepsy; movement disorders; spasticity; dystonia; surgical innovation; minimally invasive surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advances in Educational Neuroscience: Current Status and Future Directions

edited by

Antonio Luque De La Rosa

, Alejandro Vargas Serrano and Celia Gallardo Herrerías

submission deadline 17 Oct 2025 | 4 articles | Viewed by 14992 | Submission Open

Keywords: educational neuroscience; cognitive development; pedagogical strategies; student diversity; inclusive learning; neuroscientific applications; educational research; neuroscience-based interventions; innovative educational practices; theoretical and empirical approaches

(This special issue belongs to the Section Developmental Neuroscience)

Clinical Management of Cognitive Disorders in Neurodegenerative Patients

edited by

Viviana Lo Buono

submission deadline 17 Oct 2025 | 1 articles | Viewed by 2714 | Submission Open

Keywords: neurodegenerative disorders; cognitive impairment; cognitive rehabilitation; dementia; multiple sclerosis; Parkinson’ s disease; Huntington corea; TMS

(This special issue belongs to the Section Neurorehabilitation)

New Insights Into the Treatment of Subjective Tinnitus

edited by Mark N. Wallace

submission deadline 20 Oct 2025 | Viewed by 259 | Submission Open

Keywords: tinnitus neurobiology; tinnitus pathophysiology; non-invasive electrical stimulation; bimodal therapy; pharmacotherapy; tinnitus management; neurorehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Artificial Intelligence (AI) in Sleep Medicine

edited by

Shahab Haghayegh

submission deadline 20 Oct 2025 | Viewed by 216 | Submission Open

Keywords: artificial intelligence; sleep medicine; machine learning; health prediction; sleep monitoring

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Computational Intelligence and Brain Plasticity

edited by

Gianluca Borghini

, Riccardo Barbieri, Viviana Mucci, Hong Zeng and

Alessandra Anzolin

submission deadline 24 Oct 2025 | 4 articles | Viewed by 11077 | Submission Open

Keywords: brain plasticity; learning process; cognitive training; mental state assessment; cognitive rehabilitation; high-resolution eeg; brain connectivity; cognitive control behaviour; artificial intelligence; hypers-canning; multivariate autoregressive models

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Mechanisms Underlying the Neuropathic/Chronic Pain Development and Maintenance: Focus on Pharmacological Targets and Therapeutic Approaches

edited by

Giada Amodeo

submission deadline 25 Oct 2025 | 1 articles | Viewed by 718 | Submission Open

Keywords: neuropathic pain; chronic pain; mood alteration; neurons; glia cells; cytokines; neuroinflammation

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Contributions of Multisensory Processing and Integration in Successful Ageing

edited by Argiro Vatakis

submission deadline 25 Oct 2025 | Viewed by 241 | Submission Open

Keywords: multisensory; sensory; ageing; multisensory integration; multisensory processing; healthy ageing

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Stroke: Epidemiology, Diagnosis, Etiology, Treatment, and Prevention

edited by Rubens José Gagliardi

submission deadline 30 Oct 2025 | Viewed by 176 | Submission Open

Keywords: stroke; cerebrovascular disease; epidemiology; thrombolysis; thrombectomy; risk factors; ischemia

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Non-Invasive Brain Stimulation

edited by

Mariagiovanna Cantone

and

Giuseppe Lanza

submission deadline 31 Oct 2025 | 2 articles | Viewed by 6639 | Submission Open

Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

How to Rewire the Brain—Neuroplasticity

edited by

Jianyang Du

and Hui Lu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5465 | Submission Open

Keywords: brain circuits; neural networks; synaptic plasticity; neural development; network dynamics; neural coding; information processing; neuron– glia interaction; behavioral output; neurological disorders

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Editorial Board Collection Series: Advances in Neuro-Oncology

edited by

Terry Lichtor

submission deadline 31 Oct 2025 | 6 articles | Viewed by 4819 | Submission Open

Keywords: brain tumors; gliomas; cytokine gene vaccine therapy; immunotherapy; angiogenesis; checkpoint inhibitors; dendritic cell therapy

(This special issue belongs to the Section Neuro-oncology)

Modulating Brain Network Dynamics Through Training: Impacts on Perception, Cognition, and Action in Health and Disorder

edited by

Mukesh Dhamala

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3589 | Submission Open

Keywords: perception; cognition; motor actions; behavioral training; music; video game playing; neuroimaging; computational models; physical exercise

(This special issue belongs to the Section Behavioral Neuroscience)

Molecular and Neuroimaging Biomarkers in Alzheimer’s Disease and Frontotemporal Lobar Degeneration

edited by

Rodolfo Gabriel Gatto

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2322 | Submission Open

Keywords: neuroimaging; biomarkers; genetic and molecular biology; connectomics; neuropathology; neuropsychological measures; dementia; preclinical models; alzheimer’ s disease; frontotemporal dementia

(This special issue belongs to the Section Neurodegenerative Diseases)

Understanding Human Social Cognition: Integration of Neural, Cognitive, Behavioral, Affective, and Social Determinants

edited by

Eduar Herrera

submission deadline 31 Oct 2025 | 1 articles | Viewed by 830 | Submission Open

Keywords: social cognition; neural; cognitive; affective; social determinants

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroimaging and Biomarker-Guided Neuromodulation: Advances in Personalized Brain and Autonomic Stimulation

edited by Mohsen Mosayebi-Samani and

Desmond Agboada

submission deadline 31 Oct 2025 | 1 articles | Viewed by 811 | Submission Open

Keywords: neuromodulation; brain stimulation; autonomic regulation; neuroimaging; biomarkers; AI-driven Closed-loop Systems; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); deep brain stimulation (DBS); transcranial ultrasound stimulation (TUS); vagus nerve stimulation (tVNS); heart rate variability (HRV); biofeedback; magnetic resonance imaging (MRI); electroencephalography (EEG); functional near-infrared spectroscopy (fNIRS); epilepsy; depression; stroke; Alzheimer; PTSD; anxiety

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Emotional Recognition and Behavioral Regulation: An Integral Perspective

edited by

Ángel Romero Martínez

submission deadline 31 Oct 2025 | 1 articles | Viewed by 346 | Submission Open

Keywords: behavioral regulation; emotion decoding; emotion recognition; mental disorders; personality disorders; violence

(This special issue belongs to the Section Neuropsychology)

The Impact of Self and Reward on Cognitive Processes

edited by Ada Kritikos

submission deadline 31 Oct 2025 | Viewed by 302 | Submission Open

Keywords: self-prioritisation; memory self-reference effects; source and recognition memory; decision making; value modulated attentional capture; reward bias; ownership; self-evaluation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Advancements and Future Directions in Real-Time fMRI Neurofeedback Research

edited by Meghan Martz, Scott Peltier and Stefanie Russman Block

submission deadline 31 Oct 2025 | Viewed by 268 | Submission Open

Keywords: neurofeedback; real-time fMRI; neuromodulation; imaging methods; self-regulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Displaying special issue 51-100 on page 2 of 6.

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