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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Inflammation and Its Treatment in Spinal Cord Injury and Neurodegenerative Diseases

edited by Angélica Coyoy-Salgado,

Julio Morán

and

Julia Jeanett Segura-Uribe

submission deadline 31 May 2026 | Viewed by 16 | Submission Open

Keywords: spinal cord injury; neuroprotection; neurodegenerative diseases; oxidative stress; inflammatory biomarkers; neuroregeneration; therapeutic strategies

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Current Advances in Intracranial Aneurysms: From Basic to Clinical Research

edited by Yanning Rui

submission deadline 10 Jun 2026 | 1 articles | Viewed by 1825 | Submission Open

Keywords: intracranial aneurysm; causes; treatment; clinical trials

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Fetal Foundations of Cognition: Tracing Neurodevelopmental Pathways from an Integrated Perspective

edited by Pasquale Anthony Della Rosa and Cristina Baldoli

submission deadline 10 Jun 2026 | Viewed by 432 | Submission Open

Keywords: fetal neurodevelopment; neuroimaging techniques; cognitive outcomes; integrated perspectives; methodological innovations

(This special issue belongs to the Section Developmental Neuroscience)

Advances in Neurorehabilitation of Movement Disorders

edited by

Mariusz Drużbicki

and

Agnieszka Guzik

submission deadline 10 Jun 2026 | Viewed by 81 | Submission Open

Keywords: neurorehabilitation; virtual reality; robotic rehabilitation; advanced technologies; gait

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Using Neuroimaging to Explore Neurodegenerative Diseases

edited by

Ting Shen

submission deadline 15 Jun 2026 | 2 articles | Viewed by 2612 | Submission Open

Keywords: neuroimaging; neurodegenerative diseases; multidisciplinary research; imaging-omics study; multimodal integration; AI-driven analytics

(This special issue belongs to the Section Neurodegenerative Diseases)

Exploration of the Effects of Circadian Rhythms on Behavior and Physiology

edited by Christos Frantzidis and Kalliopi Megari

submission deadline 15 Jun 2026 | Viewed by 388 | Submission Open

Keywords: behavior; chronobiology; computational modeling; depression; immune function; metabolism; neurodegeneration; sleep deprivation; translational neuroscience; wearable technology

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neurosurgery on Epilepsy

edited by

Takehiro Uda

submission deadline 15 Jun 2026 | Viewed by 30 | Submission Open

Keywords: epilepsy surgery; stereoelectroencephalography (SEEG); functional neurosurgery; preoperative evaluations; minimally invasive techniques

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

How to Rewire the Brain—Neuroplasticity

edited by

Jianyang Du

and Hui Lu

submission deadline 19 Jun 2026 | 4 articles | Viewed by 14353 | Submission Open

Keywords: brain circuits; neural networks; synaptic plasticity; neural development; network dynamics; neural coding; information processing; neuron– glia interaction; behavioral output; neurological disorders

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neuroimaging and Biomarker-Guided Neuromodulation: Advances in Personalized Brain and Autonomic Stimulation

edited by Mohsen Mosayebi-Samani and

Desmond Agboada

submission deadline 19 Jun 2026 | 3 articles | Viewed by 3786 | Submission Open

Keywords: neuromodulation; brain stimulation; autonomic regulation; neuroimaging; biomarkers; AI-driven Closed-loop Systems; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); deep brain stimulation (DBS); transcranial ultrasound stimulation (TUS); vagus nerve stimulation (tVNS); heart rate variability (HRV); biofeedback; magnetic resonance imaging (MRI); electroencephalography (EEG); functional near-infrared spectroscopy (fNIRS); epilepsy; depression; stroke; Alzheimer; PTSD; anxiety

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Biomedical Research and Clinical Studies of Parkinson’s Disease and Atypical Parkinsonian Disorders

edited by

Frank C. Church

and Stefania Brotini

submission deadline 19 Jun 2026 | Viewed by 404 | Submission Open

Keywords: neurodegenerative diseases; Parkinson’ s disease (PD); atypical parkinsonian disorders (APDs); Alzheimer’ s disease (AD); frontotemporal dementia (FTD); Dementia with Lewy Body (DLB); Multiple System Atrophy Parkinsonian Variant (MSA-P); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD); biomarkers of PD and APD; pathophysiology of neurodegeneration in PD and APD; α -synuclein; beta-amyloid; and tau; role of exercise in therapy for neurodegenerative disorders (PD and APD); recent discoveries in the genetics and therapies of neurodegenerative dementias in PD and APD; brain plasticity; Complementary & Alternative Medicine (CAM) approaches in PD and APD; research aimed to understand the role of neuroinflammation in PD and APD; advances in the role of a dysfunctional immune system in the etiology of PD and APD; mitochondria and cellular energy problems in PD and APD.

(This special issue belongs to the Section Neurodegenerative Diseases)

Quality of Life in Older Adults with Musculoskeletal or Neuromuscular Disorders: Assessment and Intervention Strategies

edited by

Tatsunori Ikemoto

submission deadline 20 Jun 2026 | Viewed by 131 | Submission Open

Keywords: musculoskeletal disorder (MSD); neuromuscular disorder (NMD); pain; numbness; muscle weakness; functional decline; quality of life; aging

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Robot- and Brain Computer Interface Therapies for Neurorehabilitation: Current State of the Art and Applications

edited by

Amin Hekmatmanesh

submission deadline 20 Jun 2026 | Viewed by 85 | Submission Open

Keywords: robot; brain computer interface; neurorehabilitation; machine learning

(This special issue belongs to the Section Neurorehabilitation)

Emotional Dysregulation: From Neurodevelopment to Adult Psychopathology—a Transdiagnostic Perspective

edited by

Giulio E. Brancati

submission deadline 20 Jun 2026 | Viewed by 58 | Submission Open

Keywords: emotional dysregulation; affective instability; irritability; neurodevelopmental disorders; transdiagnostic psychopathology; comorbidity; internalizing disorders; externalizing disorders; attention-deficit/hyperactivity disorder; mood disorders

(This special issue belongs to the Section Developmental Neuroscience)

Controlling Emotion: Neural Systems and Psychological Strategies

edited by

Jennifer J. Quinn

submission deadline 20 Jun 2026 | Viewed by 52 | Submission Open

Keywords: neuroplasticity; cortical-subcortical interactions; development; habit; psychopathology; intervention; regulation; cognitive strategies

(This special issue belongs to the Section Neuropsychology)

Research Progress and Insights into Brain Visual Mechanisms

edited by

Thiago P. Fernandes

and

Guifen Chen

submission deadline 20 Jun 2026 | Viewed by 31 | Submission Open

Keywords: visual perception; sensory neuroscience; visual neuroscience; brain mechanisms; neural basis of vision; spatial cognition

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Alzheimer’s Disease and Dementia: Bridging Clinical Research and Brain Stimulation

edited by

Lucia Mencarelli

submission deadline 20 Jun 2026 | Viewed by 18 | Submission Open

Keywords: Alzheimer’ s disease; dementia; cognitive decline; brain stimulation; transcranial magnetic stimulation (TMS); transcranial electric stimulation (tES); neurorehabilitation; neuromodulation; translational neuroscience

(This special issue belongs to the Section Neurodegenerative Diseases)

Immune Response Dysregulation in Neurological Infections: Diagnostic and Therapeutic Challenges

edited by

Ryutaro Kajihara

submission deadline 20 Jun 2026 | Viewed by 5 | Submission Open

Keywords: neurological infections; immune response dysregulation; neuroinflammation; diagnostic biomarkers; therapeutic strategies; viral encephalitis; bacterial meningitis; neuroimmunology

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Evolved Affects: Evolutionary Perspectives in Affective Neuroscience

edited by

Ivana Hromatko

and

Una Mikac

submission deadline 25 Jun 2026 | Viewed by 96 | Submission Open

Keywords: affective neuroscience; evolutionary psychology; adaptive function of emotions; domain-specificity; proximal mechanisms; neural correlates; hormonal correlates; ecological context; emotion and adaptation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Intracranial Pressure Management in Acute Brain Injury

edited by

Alessandro Bertuccio

submission deadline 25 Jun 2026 | Viewed by 84 | Submission Open

Keywords: severe brain trauma injury; subarachnoid hemorrhage (SAH); brain hemorrhage; stroke; intracranial pressure (ICP); monitoring; neurocritical care; biomarkers

(This special issue belongs to the Section Systems Neuroscience)

Astrocytes in Brain Health and Disease: From Development to Neurodegeneration

edited by

Luan Pereira Diniz

submission deadline 28 Jun 2026 | Viewed by 91 | Submission Open

Keywords: astrocytes; mitochondrial dynamics; neuroinflammation; glia– neuron interaction; brain aging; synaptic regulation; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; astrocyte-targeted therapy

(This special issue belongs to the Section Neuroglia)

Optimizing Driving Safety: Neurocognitive Insights, Health-Promoting Strategies, and Policy Innovation

edited by

Foteini Christidi

Pinelopi Vlotinou

and

Anna Tsiakiri

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2907 | Submission Open

Keywords: driving; cognitive; sensory; and motor functions; decision-making; public health; aging; brain changes; cognitive decline

(This special issue belongs to the Section Behavioral Neuroscience)

Exploring the Neurobiology of the Sensory-Motor System

edited by

Daya Shankar Gupta

and Hubert Löffler

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1870 | Submission Open

Keywords: sensory; perception; motor; execution; cognitive functions; space of the brain; temporal-spatial; time dimension

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Applications of fMRI (Functional Magnetic Resonance Imaging) in Neuropsychiatry and Neurological Disease

edited by

Vincenzo Alfano

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1034 | Submission Open

Keywords: functional MRI (fMRI); neuropsychiatric disorders; neurological disease; brain connectivity; functional connectivity; neuroimaging; brain networks

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Ageing and Visual Working Memory: Cognitive and Neural Perspectives

edited by

Jean-Francois Delvenne

submission deadline 30 Jun 2026 | Viewed by 126 | Submission Open

Keywords: ageing; memory; cognitive/physical health; quality of life; cognition; prevention; cognitive decline

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

New Insights into Movement Generation: Sensorimotor Processes—2nd Edition

edited by

Koichi Hiraoka

submission deadline 30 Jun 2026 | Viewed by 60 | Submission Open

Keywords: motor plan; somatosensation; sensory– motor integration; feedback; vision; motor execution; movement; motor control; stimulus– response mapping

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Exploring Rehabilitation Strategies and Biomarkers for Brain Injury

edited by Ping-Hong Yeh

submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open

Keywords: traumatic brain injury (TBI); biomarkers; neuroinflammation; diffuse axonal injury (DAI); neuroimaging; neuropsychological assessment

(This special issue belongs to the Section Neurorehabilitation)

New Approaches in the Exploration of Parkinson’s Disease: 2nd Edition

edited by Carla Masala,

Paolo Solla

Francesco Loy

and

Tommaso Ercoli

submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open

Keywords: Parkinson’ s disease; neurodegenerative disorders; nonmotor symptoms; quality of life; cognition; olfactory deficits

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Exploration of Cerebrovascular Diseases: From Preclinical Research to Treatment—2nd Edition

edited by

Basil Grüter

and

Martina Sebök

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: intracranial aneurysm; arterio-venous malformation (AVM); dural arterio-venous fistula (AVF); ischaemic stroke; chronic steno-occlusive disease

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Sexual Behaviours and Mental Health

edited by

Rafał Gerymski

submission deadline 30 Jun 2026 | Viewed by 34 | Submission Open

Keywords: sexual behaviors; mental health; well-being; sexuality; neuropsychology

(This special issue belongs to the Section Neuropsychiatry)

Neurocognitive Deficits and Remediation in Severe Mental Illness: Mechanisms and Treatments

edited by Veronica B. Perez

submission deadline 30 Jun 2026 | Viewed by 34 | Submission Open

Keywords: Severe mental illness; Psychosis/Schizophrenia; Neurocognition/neurophysiology; Psychosocial Function; Cognitive remediation;

(This special issue belongs to the Section Neuropsychiatry)

Intraoperative Neurophysiology: New Perspectives and Clinical Applications

edited by Riccardo Budai and Giada Pauletto

submission deadline 30 Jun 2026 | Viewed by 27 | Submission Open

Keywords: IOM (intra operative monitoring); MEP (motor evoked potentials); SEP (somatosensory evoked potentials); BAEP (brainstem acoustic evoked potentials); VEP (visual evoked potentials); EMG (electromyography); EEG (electroencephalography); EcoG (electrocorticography); epilepsy; cerebral tumors

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

From Circuits to Symptoms: Advances in Psychiatry and Brain Science

edited by Stefania Bonaccorso

submission deadline 10 Jul 2026 | Viewed by 74 | Submission Open

Keywords: neurosciences; mental health; biomarkers; inflammation; AI; digital psychiatry; phenomenology; psychopathology; psychedelics

(This special issue belongs to the Section Neuropsychiatry)

Cognitive Control in Human–AI Interaction: Neural and Behavioral Perspectives

edited by

Gioele Gavazzi

submission deadline 10 Jul 2026 | Viewed by 70 | Submission Open

Keywords: cognitive control; human– artificial intelligence interaction; inhibition & AI

(This special issue belongs to the Section Behavioral Neuroscience)

Mental Health and Justice: New Advances in Forensic Psychiatry

edited by

Andrea Cioffi

submission deadline 14 Jul 2026 | Viewed by 214 | Submission Open

Keywords: forensic psychiatry; legal medicine; ethics and mental health; psychiatry in correctional settings; criminal responsibility; expert witness; risk assessment; violent behavior; psychiatrist’ s professional liability

(This special issue belongs to the Section Neuropsychiatry)

Translating Gut–Brain Crosstalk into Novel Neurological Treatments

edited by

Diego Iacono

submission deadline 15 Jul 2026 | Viewed by 25 | Submission Open

Keywords: gut– brain axis; central nervous system; enteric nervous system; anatomy; microbiota; GI-to-brain signals; brain-to-GI signals; neuroinflammation

(This special issue belongs to the Section Systems Neuroscience)

The Influence of Genetic/Environmental Risk Factors on Early Brain Development

edited by Duy Phan

submission deadline 15 Jul 2026 | Viewed by 6 | Submission Open

Keywords: neurodevelopmental disorders; human genomics; whole-exome sequencing; whole-genome sequencing; neonatal neurology; epilepsy; seizures; congenital malformations

(This special issue belongs to the Section Systems Neuroscience)

The Impact of Social Media on Human Behavior and Mental Health

edited by

Ebenezer Larnyo

and Henry Asante Antwi

submission deadline 23 Jul 2026 | Viewed by 423 | Submission Open

Keywords: social media; mental health; human behavior; psychological well-being; digital addiction; cognitive impairment; online communities; public health; health behavior change; algorithmic bias

(This special issue belongs to the Section Neuropsychology)

Chemotherapy-Associated Brain Damage—Translational Insights from Pre-Clinical and Clinical Research

edited by

Nikola Stojanović

submission deadline 25 Jul 2026 | Viewed by 68 | Submission Open

Keywords: chemotherapeutics; brain damage; brain fog; translation studies; preventing brain damage

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advances in Theory and Applications in Geriatric Musculoskeletal and Neurological Therapy

edited by Anna Christakou

submission deadline 25 Jul 2026 | Viewed by 8 | Submission Open

Keywords: myopathy; dementia; geriatric medicine; geriatric physiotherapy; osteoporosis; falls; arthritis; muscle weakness; shoulder dysfunction; rehabilitation

(This special issue belongs to the Section Systems Neuroscience)

Interlimb Transfer of Sensorimotor Learning

edited by

Jinsung Wang

and

Yuming Lei

submission deadline 30 Jul 2026 | Viewed by 44 | Submission Open

Keywords: inter-limb transfer; inter-manual transfer; cross-education; sensorimotor learning; motor adaptation; skill acquisition; motor control; neuroplasticity

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Decoding Motor Control: Multimodal Approaches to Cortical Plasticity and Learning

edited by

Gonzalo Marquez

and

David Colomer-Poveda

submission deadline 30 Jul 2026 | Viewed by 22 | Submission Open

Keywords: motor control; cortical plasticity; motor learning; multimodal approaches; neurorehabilitation; brain– machine interfaces; computational neuroscience; neuroimaging; electrophysiology; biomechanics

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Human-Centered Robotics Applications in Rehabilitation of Individuals with Neurological Conditions

edited by Giovanni Morone

submission deadline 31 Jul 2026 | Viewed by 195 | Submission Open

Keywords: robotics; neurological disabilities; stroke; gait; rehabilitation

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Biobehavioral Neuroscience and Pain Medicine: Assessment and Management of Pain

edited by

Raúl Ferrer-Peña

and

Francisco Gurdiel-Álvarez

submission deadline 31 Jul 2026 | Viewed by 192 | Submission Open

Keywords: biobehavioral neuroscience; chronic pain; pain modulation; emotion and motor control; brain plasticity; pain assessment; neurobehavioral markers; central sensitization; behavioral interventions; translational pain research

(This special issue belongs to the Section Behavioral Neuroscience)

Targeted Therapy of Glioma: Current Developments in Targeted Drug Delivery Systems

edited by Łukasz Uram

submission deadline 31 Jul 2026 | Viewed by 58 | Submission Open

Keywords: glioblastoma multiforme therapy; targeted glioma therapy; in vivo and in vitro studies; blood– brain barrier crossing; repurposing drugs; nanoparticles as targeting factors

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovative Research on the Health, Physiological and Neuroscientific Consequences of Mental Health Conditions

edited by

Jeffrey L. Kibler

submission deadline 31 Jul 2026 | Viewed by 43 | Submission Open

Keywords: health risks; psychophysiological; neuroscience; mental health

(This special issue belongs to the Section Neuropsychology)

From Neural Mechanisms to Plasticity-Driven Therapies: A Focus on Auditory Processing

edited by Giulia Cartocci,

Bianca Maria Serena Inguscio

Dario Rossi

and Saviana Antonella Barbati

submission deadline 31 Jul 2026 | Viewed by 25 | Submission Open

Keywords: neuroplasticity; sensory deprivation; hearing loss; cochlear implants; hearing aids; sensory disorders

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Chronic Pain: Symptoms, Causes, Real World Evidence, and Diagnosis

edited by Guy Hans

submission deadline 1 Aug 2026 | Viewed by 37 | Submission Open

Keywords: neuropathic pain; visceral pain; nociplastic pain; pharmacology of pain; invasive pain therapies; multidisciplinary approach; real-world evidence; pre-emptive analgesia; diagnostic evaluation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neuroimaging Biomarkers for the Diagnosis of Mental Disorders

edited by

Fabrício Pereira

submission deadline 10 Aug 2026 | Viewed by 108 | Submission Open

Keywords: neuroimaging biomarkers; multimodality imaging; precision psychiatry; translational neuropsychiatric research; neuroimaging-informed phenotype; personalized mental health; computer-aided diagnosis; artificial intelligence in psychiatry; imaging-based prognosis

(This special issue belongs to the Section Neuropsychiatry)

Neuroimmunology: Past, Present, and Promise

edited by

Maria Elsa Gambuzza

submission deadline 10 Aug 2026 | Viewed by 25 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative disorders; multiple sclerosis; neurological disorders; neuropsychiatric disorders; peripheral nervous system; neuro-oncological conditions

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Bridging Neurodegeneration and Neuroinflammation: Novel Therapeutic Approaches

edited by

Maheedhar Kodali

submission deadline 15 Aug 2026 | Viewed by 38 | Submission Open

Keywords: neurodegeneration; neuroinflammation; transcriptomic alterations; extracellular vesicles; mTOR signaling; autophagy and mitophagy; synaptogenesis brain repair preclinical models; therapeutic interventions

(This special issue belongs to the Section Neurodegenerative Diseases)

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