Inflammation and Its Treatment in Spinal Cord Injury and Neurodegenerative Diseases

Dear Colleagues,

Inflammation plays a central and complex role in the pathophysiology of both spinal cord injury (SCI) and neurodegenerative diseases. Traditionally regarded as a secondary contributor to neural damage, neuroinflammation is now understood as a dynamic process that can drive both injury progression and repair, depending on its timing, intensity, and cellular context. This Special Issue aims to advance the current understanding of inflammatory mechanisms and therapeutic strategies in SCI and in neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, etc.

The scope of this issue includes experimental and clinical research focused on inflammation-mediated mechanisms of neural damage, as well as the evaluation of anti-inflammatory and neuroprotective interventions. Studies addressing disease progression, cellular and molecular mediators of inflammation, and treatment efficacy in both SCI and neurodegenerative disorders are particularly encouraged.

We welcome original research articles, comprehensive reviews, and translational studies that contribute to the development of targeted anti-inflammatory therapies across spinal cord injury and major neurodegenerative diseases.

Dr. Angélica Coyoy-Salgado
Prof. Dr. Julio Morán
Dr. Julia Jeanett Segura-Uribe
Guest Editors

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