Immune Response Dysregulation in Neurological Infections: Diagnostic and Therapeutic Challenges

Dear Colleagues,

Neurological infections represent a major challenge in medicine due to their complex interplay between pathogens and the host immune system. Dysregulation of immune responses within the central nervous system can result in neuroinflammation, neuronal injury, and persistent neurological deficits, often complicating both diagnosis and treatment. While recent advances have improved our understanding of these processes, many critical questions remain regarding the mechanisms of immune-mediated pathology and the development of effective interventions.

This Special Issue aims to bring together original research, reviews, and case reports that address the diagnostic and therapeutic challenges posed by immune response dysregulation in neurological infections, including viral, bacterial, and emerging neurotropic pathogens. We particularly welcome studies on novel biomarkers and innovative therapeutic strategies, as well as translational research that bridges basic immunology and clinical practice. By fostering multidisciplinary collaboration, this Special Issue seeks to advance knowledge and improve outcomes for patients affected by these complex disorders.

Dr. Ryutaro Kajihara
Guest Editor

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