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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1160 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Applications and Developments of Metal-Based Drugs

edited by

Sajal Sen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1104 | Submission Open

Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Feature Reviews in Ophthalmology

edited by

Ana Maria Dascalu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 801 | Submission Open

Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition

edited by

Maciej Walędziak

and Anna Maria Różańska-Walędziak

submission deadline 31 Jan 2026 | 1 articles | Viewed by 774 | Submission Open

Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 696 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Emerging Technologies in the Diagnosis and Management of Neurological Disorders

edited by

Luca Filippi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 685 | Submission Open

Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition

edited by

Da-Wen Lu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 681 | Submission Open

Keywords: glaucoma; ocular pharmacology; ocular disease

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 31 Jan 2026 | Viewed by 581 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules

edited by Monika Papiez

submission deadline 31 Jan 2026 | Viewed by 411 | Submission Open

Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers

(This special issue belongs to the Section Cancer Biology and Oncology)

Extracellular Vesicles: Research Advances in Cancer Treatment and Diagnostics

edited by

Luís R. Raposo

submission deadline 31 Jan 2026 | Viewed by 317 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer therapy; diagnostics; cellular communication; tumor microenvironment; EV biogenesis

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 31 Jan 2026 | 1 articles | Viewed by 302 | Submission Open

Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Research in Neurorehabilitation, 2nd Edition

edited by

Manuel Gaviria

submission deadline 31 Jan 2026 | Viewed by 288 | Submission Open

Keywords: mechanisms; CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; neuroprosthetics; brain– computer interfaces; neurodevelopmental disorder

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Advances in Epilepsy Research

edited by Duyu A. Nie

submission deadline 31 Jan 2026 | Viewed by 284 | Submission Open

Keywords: disease mechanisms; genetics; biomarkers; epilepsy surgery; electroencephalogram; animal models; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation

edited by Chao Liu

submission deadline 31 Jan 2026 | Viewed by 282 | Submission Open

Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells

(This special issue belongs to the Section Immunology and Immunotherapy)

New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition)

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 31 Jan 2026 | 1 articles | Viewed by 277 | Submission Open

Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Neural Organoids: Advancing Our Understanding of the Central and Peripheral Nervous Systems

edited by Birtele Marcella

submission deadline 31 Jan 2026 | Viewed by 234 | Submission Open

Keywords: neural organoids; brain development; tissue engineering; disease modeling; peripheral nervous system; single-cell analysis; neural circuits; bioengineering; stem cells; neurodevelopmental disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Fatty Acid Metabolism as the Markers of Civilization Diseases (3rd Edition)

edited by

Arleta Drozd

submission deadline 31 Jan 2026 | Viewed by 198 | Submission Open

Keywords: fatty acids; lipidomics; biochemistry; infalmmation; pathophysiological mechanisms; lipid mediators; gut microbiota; NAFLD/NASH; insulin resistance; type 2 diabetes; endocine diseases; cardiovascular diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanotechnology in Pharmaceuticals

edited by Pratap Basim,

Geetha Vaskuri

and

Nagavendra Kommineni

submission deadline 31 Jan 2026 | Viewed by 195 | Submission Open

Keywords: nanotechnology; drug delivery; diagnostics; theranostics; biomimetics; nanocarriers; targeted delivery; routes of administration

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Atrial Fibrillation: From Pathogenesis to Treatment Strategies

edited by

Dimitrios A. Vrachatis

, Theodore G. Papaioannou and

Ioannis Anagnostopoulos

submission deadline 31 Jan 2026 | Viewed by 170 | Submission Open

Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)

edited by Ioannis Zachos and

Panagiotis Vlachostergios

submission deadline 31 Jan 2026 | Viewed by 169 | Submission Open

Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics

edited by Vetriselvan Subramaniyan

submission deadline 31 Jan 2026 | Viewed by 160 | Submission Open

Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research

(This special issue belongs to the Section Gene and Cell Therapy)

Additive Manufacturing in Biomedical Applications

edited by

Paweł Turek

submission deadline 31 Jan 2026 | Viewed by 160 | Submission Open

Keywords: additive manufacturing; scaffolds; implant; anatomical models; in vivo; in vitro; surface texture; geometrical accuracy; biomaterials; surface roughness

(This special issue belongs to the Section Biomedical Engineering and Materials)

Organisms as Diagnostic Technologies: Harnessing Life for Sensing Mechanisms

edited by

Takaaki Hirotsu

and Hideshi Ishii

submission deadline 31 Jan 2026 | Viewed by 151 | Submission Open

Keywords: biological sensors; diagnostic technologies; diagnostic technologies; biological sensing mechanisms; conversion of biological signals; bio-interfaces

(This special issue belongs to the Section Biomedical Engineering and Materials)

Autonomic Disorders: From Mechanisms to Therapeutic Approaches

edited by Svetlana Blitshteyn

submission deadline 31 Jan 2026 | Viewed by 133 | Submission Open

Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Biomaterials for Tissue Repair and Regeneration

edited by Fei Xing, Wen Nie and Zhao Chen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 131 | Submission Open

Keywords: biomaterials; nanomaterials; tissue repair; 3D printing; functionals biomaterials; biomaterial science; tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives

edited by

Sandeep Kumar

Abhishek Gupta

and

Atul Kumar Pandey

submission deadline 31 Jan 2026 | Viewed by 130 | Submission Open

Keywords: metabolism; diabetes; obesity; nutrition; AMPK and mTOR

(This special issue belongs to the Section Endocrinology and Metabolism Research)

The Pleiotropic Effects of Statins: Anti-Inflammatory, Anti-Coagulant, and Anti-Proliferative Properties

edited by

Maria Grau

submission deadline 31 Jan 2026 | Viewed by 128 | Submission Open

Keywords: hydroxymethylglutaryl-CoA reductase inhibitors; pharmacoepidemiology; anti-inflammatory properties; anti-coagulant properties; anti-proliferative properties

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Signal Peptides in Health and Disease: Molecular Mechanisms and Therapeutic Potential

edited by

Renata Perlikowska

submission deadline 31 Jan 2026 | Viewed by 123 | Submission Open

Keywords: signal peptides; protein targeting; protein trafficking; therapeutic peptides; synthetic signal peptides; signal recognition particle; drug delivery system; biomarker discovery

(This special issue belongs to the Section Molecular and Translational Medicine)

Cell Metabolism in Brain Physiology and Pathology: From Molecular Mechanisms to Therapeutic Targets

edited by

Marco Segatto

and Mayra Colardo

submission deadline 31 Jan 2026 | Viewed by 123 | Submission Open

Keywords: autophagy; energy homeostasis; glucose metabolism; lipids; metabolism; nervous system; oxidative stress; protein metabolism; neurodegeneration; neurodevelopment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Biologics for Bone and Soft Tissue Regeneration: What Is New, What Is True—Second Edition

edited by

Ashim Gupta

Nicola Maffulli

and

Erwin Pavel Lamparelli

submission deadline 31 Jan 2026 | Viewed by 114 | Submission Open

Keywords: regenerative medicine; stem cells; exosomes; musculoskeletal injuries; osteoarthritis; tissue regeneration; tissue engineering; biologics; bone; soft tissue

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advanced Research in Liver Diseases

edited by

Marta Melis

submission deadline 31 Jan 2026 | Viewed by 113 | Submission Open

Keywords: liver; obesity; alcohol; oxidative stress; nutrients; vitamins; metabolism; homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Signatures and Therapeutic Strategies in Urological Cancers

edited by Haoyue Sheng

submission deadline 31 Jan 2026 | Viewed by 111 | Submission Open

Keywords: urological cancers; molecular signatures; precision medicine; non-coding RNAs; tumor microenvironment

(This special issue belongs to the Section Molecular and Translational Medicine)

Antibody Responses to Viral Infections: Insights from Structural Biology

edited by Pragati Agnihotri and

Sharanbasappa Karade

submission deadline 31 Jan 2026 | Viewed by 108 | Submission Open

Keywords: crystal structure; virus– antibody complexes; broadly neutralizing antibodies; immunology; epitope mapping

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Tumour Angiogenesis and Anti-Angiogenic Therapy

edited by

Krishna Priya Syama

submission deadline 31 Jan 2026 | Viewed by 107 | Submission Open

Keywords: tumour angiogenesis; vascularization; endothelial cells; pericytes; vascular endothelial growth factor (VEGF); bevacizumab; micro vessel density; anti-angiogenic therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications

edited by

Xiao Liu

submission deadline 31 Jan 2026 | Viewed by 102 | Submission Open

Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Shock Syndromes: Pathophysiology, Diagnostics and Emerging Therapeutics Across the Clinical Spectrum

edited by

George E. Zakynthinos

and

Evangelos Oikonomou

submission deadline 31 Jan 2026 | Viewed by 101 | Submission Open

Keywords: shock; critical illness; cardiogenic shock; septic shock; hypovolemic shock; obstructive shock; inflammation; hemodynamics; artificial intelligence in medicine; precision medicine; vasopressors; mechanical circulatory support; diagnostics

(This special issue belongs to the Section Molecular and Translational Medicine)

New Treatments for Colorectal Cancer

edited by

Dhiraj Kumar Sah

submission deadline 31 Jan 2026 | Viewed by 99 | Submission Open

Keywords: biomarkers; signaling pathway; chemotherapy; reactive oxygen species; angiogenesis

(This special issue belongs to the Section Cancer Biology and Oncology)

Cell Cycle in Normal Physiology and Disease

edited by

Chen Chu

submission deadline 31 Jan 2026 | Viewed by 99 | Submission Open

Keywords: cell cycle; DNA replication; DNA damage; cyclins; cyclin-dependent kinases (CDKs); CDK inhibitors; cell proliferation; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Advancements in Research on Pancreatic Cancer: From Biomarkers to Targeted Therapies

edited by

Konstantinos Dimas

submission deadline 31 Jan 2026 | Viewed by 98 | Submission Open

Keywords: pancreatic cancer; novel biomarkers; diagnostic techniques; therapeutic approaches

(This special issue belongs to the Section Cancer Biology and Oncology)

Cancer Pharmacology

edited by Zhi Shi

submission deadline 31 Jan 2026 | Viewed by 96 | Submission Open

Keywords: cancer pharmacology; anticancer drug; cancer chemotherapy; targeted therapy; cancer immunotherapy; combination therapy; drug resistance

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Mechanisms and Novel Therapeutic Approaches for Nephrology

edited by

Fang-Fang He

submission deadline 31 Jan 2026 | Viewed by 94 | Submission Open

Keywords: chronic kidney disease; acute kidney injury; therapeutics; molecular mechanisms; biomarkers; drug discovery; regenerative medicine; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Insights into HIV: Second Edition

edited by

Konstantinos Protopapas

, Antonios Papadopoulos and

Charalampos D. Moschopoulos

submission deadline 31 Jan 2026 | Viewed by 91 | Submission Open

Keywords: HIV/AIDS; antiretroviral treatment; comorbidities; co-infection; neuroHIV

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Pathways and Their Clinical Implications in Ischemic Heart Disease and Heart Failure: From Pathophysiology to Therapeutic Strategies

edited by

Panagiotis Stachteas

and Efstratios Karagiannidis

submission deadline 31 Jan 2026 | Viewed by 90 | Submission Open

Keywords: ischemic heart disease; heart failure; molecular mechanisms; biomarkers; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation

edited by

Huifang Tang

submission deadline 31 Jan 2026 | Viewed by 89 | Submission Open

Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models

(This special issue belongs to the Section Molecular and Translational Medicine)

Biologic Drugs: The Evolution of Asthma Therapeutics

edited by

Girolamo Pelaia

and

Corrado Pelaia

submission deadline 31 Jan 2026 | Viewed by 88 | Submission Open

Keywords: severe asthma; IgE; IL-4; IL-5; IL-13; TSLP; monoclonal antibodies

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in 3D Printing for Drug Delivery Systems

edited by

Ion-Bogdan Dumitrescu

, Cristina Manuela Drăgoi and Alina Crenguța Nicolae

submission deadline 31 Jan 2026 | Viewed by 87 | Submission Open

Keywords: 3D printing; drug delivery systems; personalized medicine; pharmaceutical engineering; controlled release

(This special issue belongs to the Section Biomedical Engineering and Materials)

Bioactive Lipids in Disease: Diagnosis, Prognosis, and Pathophysiology

edited by

Xu Zhang

submission deadline 31 Jan 2026 | Viewed by 84 | Submission Open

Keywords: bioactive lipids; eicosanoids; endocannabinoids; lysophospholipids; sphingolipids; oxysterols; bile acids; lipidomics; pathophysiology; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition

edited by

David J. Rademacher

submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open

Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering

(This special issue belongs to the Section Cell Biology and Pathology)

Genetically Determined Cardiovascular Disease

edited by

Gaetano Thiene

submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open

Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Advances in Neuroprotective Agent

edited by

Mariano Catanesi

submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open

Keywords: mitochondrial disfunction; antioxidant molecules; gene therapy; stem cell; nanomedicine; cellular reprogramming

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Displaying special issue 401-450 on page 9 of 16.

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