Advanced Research in Thyroid and Parathyroid Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 216
Special Issue Editor
Interests: anaplastic thyroid cancer; targeted therapy strategies; integrated immunotherapy; tumor microenvironment
Special Issue Information
Dear Colleagues,
Thyroid and parathyroid diseases encompass a wide spectrum of conditions, ranging from benign disorders to aggressive malignancies. Thyroid cancer remains one of the most prevalent endocrine malignancies, with its incidence continuing to rise globally. While differentiated thyroid cancer (DTC) generally has a favorable prognosis when conventional treatments such as surgery, radioactive iodine (RAI) therapy, and thyroid hormone suppression are implemented, the management of aggressive subtypes—including poorly differentiated thyroid carcinoma (PDTC), anaplastic thyroid carcinoma (ATC), and medullary thyroid carcinoma (MTC)—remains a significant clinical challenge. Additionally, disorders of the parathyroid glands, particularly primary hyperparathyroidism and parathyroid carcinoma, present unique diagnostic and therapeutic challenges that warrant further investigation.
Recent advances in molecular profiling have provided deeper insights into the genetic and epigenetic alterations that promote the progression of tumors, providing a basis for novel targeted therapies and immunotherapy approaches. Furthermore, the role of calcium metabolism, parathyroid hormone regulation, and their systemic involvement in endocrine health have attracted the attention of researchers.
This Special Issue aims to highlight innovative developments in the diagnosis and treatment of thyroid and parathyroid diseases. We welcome contributions that explore innovative therapeutic strategies, precision medicine applications, and the role of tumor microenvironment modulation in disease progression. The scope of this Special Issue includes emerging biomarkers for prognosis and treatment selection, the mechanisms of treatment resistance, advances in systemic therapies, and novel surgical and radiotherapeutic techniques. We particularly welcome the submission of studies that connect laboratory discoveries with clinical applications, offering new perspectives regarding the evolving landscape of thyroid and parathyroid disease management. Through this collection, we seek to provide a comprehensive and up-to-date resource that informs future research and clinical practice.
Dr. Anping Su
Guest Editor
Manuscript Submission Information
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Keywords
- thyroid cancer treatment
- tumor microenvironment
- immunotherapy
- targeted therapy
- precision medicine
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