Genetic and Epigenetic Research on Kidney Diseases

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular Genetics and Genetic Diseases".

Deadline for manuscript submissions: 30 March 2026 | Viewed by 23

Special Issue Editor


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Guest Editor
Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Interests: chronic kidney disease; acute kidney injury; single-cell transcriptome; spatial transcriptome; epigenetic; genome perturbation
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Special Issue Information

Dear Colleagues,

Chronic kidney disease (CKD) and acute kidney injury (AKI) significantly impact global health, often resulting from complex interactions involving genetic predispositions and epigenetic modifications. Genetic factors contribute to variations in disease susceptibility, progression rates, and therapeutic responses. Epigenetic mechanisms, including DNA methylation, histone modifications, and non-coding RNAs, dynamically regulate gene expression in kidney cells and are crucial in kidney development, disease initiation, and progression.

Understanding the intricate relationship between genetics and epigenetics is vital for unraveling the pathophysiological processes underlying kidney diseases. Emerging evidence has implicated critical genes and pathways in various forms of kidney disease, offering potential targets for intervention. Additionally, epigenetic biomarkers have demonstrated promise for early detection, prognostication, and tailoring therapeutic strategies.

This Special Issue, titled “Genetic and Epigenetic Research on Kidney Diseases”, seeks high-quality submissions of original research articles, comprehensive reviews, and innovative methodologies. We invite contributions highlighting translational studies, novel biomarkers, and personalized medicine approaches, with the aim of fostering collaborative research and accelerating clinical advancements in nephrology.

Dr. Hailong Hu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • kidney disease
  • genetics
  • epigenetics
  • DNA methylation
  • non-coding RNAs
  • precision medicine
  • therapeutic target
  • nephrology

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Published Papers

This special issue is now open for submission.
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