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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice

edited by Tanveer Singh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1596 | Submission Open

Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1505 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research in Secondary Immunodeficiency in Oncohematological Diseases

edited by

Giuseppe Murdaca

and

Sebastiano Gangemi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1454 | Submission Open

Keywords: secondary immunodeficiencies and opportunistic infections; secondary immunodeficiencies and B-lymphocytes; secondary immunodeficiencies and hematological diseases; secondary immunodeficiencies and cancers; secondary immunodeficiencies and novel cancer treatments; secondary immunodeficiencies and oxidative stress

(This special issue belongs to the Section Immunology and Immunotherapy)

Protein Misfolding and Functional Impairment in Neurodegenerative Diseases

edited by

Marios Krokidis

Themis Exarchos

and

Panayiotis Vlamos

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1449 | Submission Open

Keywords: protein misfolding; chaperones; energy landscape; neurodegenerative diseases; amyloidogenesis; intrinsically disordered proteins; structure prediction algorithms; bioinformatics; molecular dynamic simulations

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic

edited by Miguel A. Ortega and

Raul Diaz-Pedrero

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1403 | Submission Open

Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Microbial Metabolites and Their Impact on Gut Homeostasis

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1298 | Submission Open

Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Sex Hormones and Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Renáta Szabó

and

Denise Börzsei

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1218 | Submission Open

Keywords: endogenous sex hormones; aging; sexual dimorphism; hormone replacement therapy; CVDs; hypertension; myocardial infarction; atherosclerosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Progress in Neonatal Pulmonary Biology

edited by

Fumihiko Namba

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1183 | Submission Open

Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome

(This special issue belongs to the Section Molecular and Translational Medicine)

Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches

edited by Alan P. Lombard

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1162 | Submission Open

Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Hepatocellular Carcinoma Pathogenesis and Therapy

edited by Junyan Tao

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1073 | Submission Open

Keywords: HCC (hepatocellular carcinoma); early diagnosis; molecular pathology characteristics; molecular target therapy; combination therapy; immune checkpoint inhibitors; precision medicine; HCC heterogeneity; drug resistance; HCC risk factors

(This special issue belongs to the Section Cancer Biology and Oncology)

Updates on Kawasaki Disease

edited by Eisuke Suganuma

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1065 | Submission Open

Keywords: coronary artery aneurysm; cluster; individualized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches

edited by

Shaoqing Yu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 907 | Submission Open

Keywords: allergic rhinitis; immunotherapy; immune mechanisms in allergy; rhinitis biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Heparan Sulfate Biology: Protein Interactions and Therapeutic Implications

edited by Miaomiao Li

submission deadline 31 Oct 2025 | 1 articles | Viewed by 813 | Submission Open

Keywords: heparan sulfate; heparin; heparanase; heparan sulfate-binding protein; heparan sulfate oligosaccharides; antibody; natural sulfated carbohydrates

(This special issue belongs to the Section Cell Biology and Pathology)

Glioma Therapy: Current Status and Future Prospects

edited by Bernd Kaina

submission deadline 31 Oct 2025 | 1 articles | Viewed by 798 | Submission Open

Keywords: glioblastoma; temozolomide; nitrosoureas; immunotherapy; biologicals; tyrosine kinase inhibitors; senotherapeutics

(This special issue belongs to the Section Cancer Biology and Oncology)

Strategies for Anticancer in p53 Mutated Cancers

edited by

Bi-He Cai

and

Ching-Feng Lien

submission deadline 31 Oct 2025 | 1 articles | Viewed by 675 | Submission Open

Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Role of Endothelial Cells in Cardiovascular Disease—2nd Edition

edited by

Lorenzo Falsetti

and

Vincenzo Zaccone

submission deadline 31 Oct 2025 | 1 articles | Viewed by 671 | Submission Open

Keywords: endothelial cells; endothelial dysfunction; cardiovascular disease; endothelial progenitor cells; atherosclerosis; thrombosis; vessel inflammation; regenerative medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Exploitation and Development of “Synthetic Lethality” Strategy for Cancer Therapy

edited by Guo Chen

submission deadline 31 Oct 2025 | Viewed by 652 | Submission Open

Keywords: anti-cancer therpies; PARP inhibitors; synthetic lethality

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Past, Present and Further Looking for Therapeutic Management of Pancreatic Ductal Adenocarcinoma (2nd Edition)

edited by

Gennaro Nappo

and

Niccola Funel

submission deadline 31 Oct 2025 | 1 articles | Viewed by 603 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; treatment pancreatic cancer; chemotherapy pancreatic cancer; radiotherapy pancreatic cancer; pancreatic cancer biology; PDAC preclinical model; biomolecular markers; theragnostic molecules; target therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Latest Advancements in Radiotherapy

edited by

Moshi Geso

submission deadline 31 Oct 2025 | 1 articles | Viewed by 602 | Submission Open

Keywords: radiobiology; dosimetry; nanoparticles; FLASH; radiation

(This special issue belongs to the Section Molecular and Translational Medicine)

Vitamin D: Latest Scientific Discoveries in Health and Disease

edited by

Mohamed Abouzid

submission deadline 31 Oct 2025 | 1 articles | Viewed by 488 | Submission Open

Keywords: vitamin D; vitamin D metabolites; metabolic pathways; vitamin D receptor; polymorphisms; pathogenesis; vitamin D deficiency

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Inflammatory Skin Diseases

edited by

Angelo Ruggiero

Luca Potestio

and

Matteo Megna

submission deadline 31 Oct 2025 | Viewed by 377 | Submission Open

Keywords: inflammatory skin diseases; pathophysiology; therapeutic strategies; novel treatments; skin disorders

(This special issue belongs to the Section Immunology and Immunotherapy)

Gut–Brain Axis and Diabetes

edited by Nikolett Bódi

submission deadline 31 Oct 2025 | Viewed by 368 | Submission Open

Keywords: diabetes; gut– brain axis; enteric nervous system; central nervous system; microbiota; enteroendocrine cells; inflammation; immune responses

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases: 2nd Edition

edited by Aifang Cheng, Beika Zhu and Fulin Ma

submission deadline 31 Oct 2025 | 1 articles | Viewed by 349 | Submission Open

Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

The Role of Oxidative Stress in Metabolic Syndrome

edited by

Bojlul Bahar

submission deadline 31 Oct 2025 | Viewed by 319 | Submission Open

Keywords: free radical; oxidative stress; ROS; NRF2; Keap1; metabolic syndrome; chronic inflammation; cardiovascular disease; obesity; diabetes

(This special issue belongs to the Section Molecular and Translational Medicine)

Unraveling the Epigenetic Blueprint: Exploring DNA Methylation and Its Integration with Omics in Health and Disease

edited by Priyadarshini Kachroo and Rinku Sharma

submission deadline 31 Oct 2025 | Viewed by 305 | Submission Open

Keywords: multiomics; networks; epigenomics; machine learning; causation; early-life exposures; aging; translational therapeutics; metabolomics; epigenomics; exposomics; proteomics; microbiome

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Epigenetic Regulation in Liver Metabolic Homeostasis and Disease

edited by Chengfei Jiang and Zhe Li

submission deadline 31 Oct 2025 | Viewed by 297 | Submission Open

Keywords: liver metabolism; epigenetic regulation; RNA modification; metabolic disorder; non-coding RNA; liver disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Updates on Tissue Repair and Regeneration Pathways

edited by

Cornel Baltă

and

Oana-Maria Boldura

submission deadline 31 Oct 2025 | Viewed by 283 | Submission Open

Keywords: tissue repair; tissue regeneration; molecular pathways involved in repair and regeneration; extracellular matrix; drug delivery systems

(This special issue belongs to the Section Biomedical Engineering and Materials)

Post Tuberculosis Lung Disease from Lung Damage to the Loss of Lung Function

edited by

Oana Cristina Arghir

and Ariadna Petronela Fildan

submission deadline 31 Oct 2025 | Viewed by 278 | Submission Open

Keywords: post-tuberculosis lung disease (PTLD); post-TB conditions; TB sequelae; obstructive post-TB disease; post-TB syndromes

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanism and Modulation in Radiotoxicity

edited by

Stephanie Puukila

, Siddhita Mhatre and Janani Iyer

submission deadline 31 Oct 2025 | Viewed by 255 | Submission Open

Keywords: radiation; cellular damage; dose; tissue sensitivity; countermeasures

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Age-Related Diseases: Molecular Mechanisms, Treatments, and Clinical Implications

edited by

Stefano Cacciatore

and

Emanuele Marzetti

submission deadline 31 Oct 2025 | Viewed by 249 | Submission Open

Keywords: aging; age-related diseases; cellular senescence; mitochondrial dysfunction; inflammation and oxidative stress; biomarkers; precision medicine; pharmacological interventions; healthy aging; translational geriatric research

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Biomarkers and Technologies in the Research and Diagnosis of Human Diseases: Second Edition

edited by

Benjamin M. Liu

submission deadline 31 Oct 2025 | Viewed by 249 | Submission Open

Keywords: pathology; diseases; biomarkers; diagnosis; novel technologies

(This special issue belongs to the Section Immunology and Immunotherapy)

PET and SPECT Imaging for the Diagnosis of Neurodegenerative Diseases

edited by Paulina Gonzalez and

Carlo Colosimo

submission deadline 31 Oct 2025 | Viewed by 235 | Submission Open

Keywords: neurodegenerative diseases; PET imaging and diagnosis; neurological disorders; clinical PET imaging; positron emission tomography

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Insights and Translational Approaches in Musculoskeletal Disorders

edited by Priyanka Kushwaha

submission deadline 31 Oct 2025 | Viewed by 216 | Submission Open

Keywords: musculoskeletal disorders; osteoarthritis; rheumatoid arthritis

(This special issue belongs to the Section Molecular and Translational Medicine)

The Molecular Mechanisms of Hearing, Balance and Deafness

edited by

Francisco J. del Castillo

submission deadline 31 Oct 2025 | Viewed by 201 | Submission Open

Keywords: hearing; balance; deafness; molecular mechanisms; genetics; transcriptomics

(This special issue belongs to the Section Molecular and Translational Medicine)

Poly-Pharmacological Effects and Mechanisms of Phytochemicals

edited by

Jiawen Shou

submission deadline 31 Oct 2025 | Viewed by 190 | Submission Open

Keywords: phytochemicals; natural products; poly-pharmacology; novel application; research updates on phytochemicals

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Treatment of HIV Infection: Strategies, New Drugs and Drug Metabolism

edited by

Salvatore Martini

submission deadline 31 Oct 2025 | Viewed by 174 | Submission Open

Keywords: HIV; long-acting; efficacy; tolerability; adherence

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Tumor Microenvironment in Cancer: Basic Science, Artificial Intelligence, and Clinical Research

edited by Rada Amin

submission deadline 31 Oct 2025 | Viewed by 153 | Submission Open

Keywords: tumor microenvironment; cancer progression; malignancies; immunotherapy; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

The Human Proteinomics in Disease, Diagnostics and Translation into Precision Medicine: Current Status and Future Prospects—2nd Edition

edited by

M. Walid Qoronfleh

submission deadline 31 Oct 2025 | Viewed by 149 | Submission Open

Keywords: proteomics; human proteome; systems biology; precision medicine; biomarker(s); disease pathogenesis; diagnostics; mass spectrometry; tandem mass spectrometry; LC-MS/MS; peptides and proteins; multiplex protein analysis; protein network; protein– protein interaction; splice variants; post-translational modifications; omics analysis; data integration; bioinformatics; artificial intelligence; deep learning

(This special issue belongs to the Section Molecular and Translational Medicine)

Photodynamic Therapy (4th Edition)

edited by

Stefano Bacci

submission deadline 31 Oct 2025 | Viewed by 149 | Submission Open

Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa

(This special issue belongs to the Section Immunology and Immunotherapy)

Stem Cell Therapy and Tissue Engineering

edited by

Nurettin Sahiner

submission deadline 31 Oct 2025 | Viewed by 126 | Submission Open

Keywords: stem cells; stem cell therapy; stem cell cancer therapy; hydrogels/cryogels; porous network biomaterials; tissue engineering

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition)

edited by

Francesco Massari

and

Pietro Scicchitano

submission deadline 31 Oct 2025 | Viewed by 120 | Submission Open

Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology, 2nd Edition

edited by Zhilong Ai

submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open

Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Type 2 Diabetes: Insulin Regulation and Therapeutic Strategies

edited by

Syed A. A. Rizvi

submission deadline 31 Oct 2025 | Viewed by 114 | Submission Open

Keywords: type 2 diabetes; insulin regulation; glycemic control; insulin resistance; therapeutic strategies; personalized medicine; GLP-1 receptor agonists; SGLT2 inhibitors; novel insulin formulations; non-insulin therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advanced Research in Anticancer Inhibitors and Targeted Therapy

edited by Changmin Peng and

Hassan Ebrahim

submission deadline 31 Oct 2025 | Viewed by 112 | Submission Open

Keywords: histone deacetylases (HDACs); YAP signaling; targeted therapy; oncogenic signaling; biomarker discovery; small-molecule inhibitors; cancer drug resistance; epigenetic therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Interaction Between Microbiota and Immunity in Health and Diseases

edited by Giuseppe Merra

submission deadline 31 Oct 2025 | Viewed by 112 | Submission Open

Keywords: microbiota; microbiome; inflammation; immunity; epithelial barrier

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Cancer-Associated Thrombosis: From Biomarkers to Diagnostic and Therapeutic Strategies to Optimize Treatment

edited by

Roberta Pancani

and Gualtiero Palareti

submission deadline 31 Oct 2025 | Viewed by 111 | Submission Open

Keywords: cancer-associated thrombosis; venous thrombosis; biomarkers; pulmonary embolism; precision medicine; diagnostic optimization

(This special issue belongs to the Section Cancer Biology and Oncology)

Biological Role of Oxidative Stress in Inflammatory Processes

edited by

Magdalena Paulina Kasprzak

submission deadline 31 Oct 2025 | Viewed by 107 | Submission Open

Keywords: oxidative stress; redox balance; antioxidants; NRF2; microbiota; bilirubin; Tlr4; inflammation

(This special issue belongs to the Section Cell Biology and Pathology)

The Intricacies of Developmental and Epileptic Encephalopathies: A Journey Towards Innovative Therapies

edited by Muhammad Nauman Arshad and Paul Davies

submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open

Keywords: cognitive; behavioral deficits

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Immune Checkpoint Regulation and Signaling Pathways in Cancer

edited by Sreeja C. Sekhar

submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open

Keywords: tumor-immune evasion and interaction; immune check point inhibition; PD-1/PDL-1 pathway; T-cell exhaustion and tumor microenvironment; single-cell profiling; therapeutic resistance; tumor-infiltrating cells; checkpoint inhibitors and immune modulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Male Reproductive Medicine: From Basic to Clinical Research

edited by Donghui Huang

submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open

Keywords: male reproductive function; spermatogenesis; hormonal regulation; genetic and epigenetic influences; environmental toxicology; male reproductive health

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 301-350 on page 7 of 15.

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