Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skin Diseases and Cell Therapy
edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum
submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open
Keywords: dermatology; psoriasis; atopic dermatitis; vitiligo; alopecia; cutaneous leishmaniasis; and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms
(This special issue belongs to the Section Gene and Cell Therapy)
Innovations and Perspectives in Kidney Transplantation
edited by Vassilis Filiopoulos
submission deadline 30 Sep 2025 | Viewed by 109 | Submission Open
Keywords: bioartificial kidney; immunology; immunosuppression; kidney transplantation; tolerance; graft rejection; graft survival; xenotransplantation; kidney regeneration
(This special issue belongs to the Section Immunology and Immunotherapy)
Matrix Biology Insights: Unraveling the Role of Proteinases, Fibroblasts, and Extracellular Matrix Metalloproteinase Inducer in the Tumor Microenvironment
edited by
submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open
Keywords: tumor microenvironment; proteinases; fibroblasts; EMMPRIN; matrix biology; extracellular matrix (ECM); matrix metalloproteinases (MMPs)
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Endothelial Dysfunction
edited by
submission deadline 30 Sep 2025 | Viewed by 107 | Submission Open
Keywords: endothelial dysfunction; atherosclerosis; nitric oxide (NO); hyperlipidemia; hypertension; hyperglycemia; vasodilation; perivascular adipose tissue (PVAT); insulin resistance
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Recent Advances in Molecular Neuroimaging
edited by
submission deadline 30 Sep 2025 | Viewed by 105 | Submission Open
Keywords: molecular neuroimaging; imaging techniques; clinical applications; imaging probes; personalized medicine; diagnostic imaging; therapeutic monitoring; clinical decision support
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Targeted Therapy of Autoimmune Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 105 | Submission Open
Keywords: autoimmune diseases; pathogenesis; targeted therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Artificial Intelligence Applications in Cancer and Other Diseases—2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 105 | Submission Open
Keywords: artificial intelligence; machine learning; neural networks; deep learning; obesity; diabetes; cancer; other diseases; pathology; drug discovery
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in Extracellular Vesicles in Therapeutics submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open
Keywords: extracellular vesicles (EVs); exosomes; regenerative medicine; immunotherapy; nanocarriers; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Biomaterials for Bone Regeneration: 2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 102 | Submission Open
Keywords: bone regeneration; bone defect; induced membrane technique; bone transport; biomaterials
(This special issue belongs to the Section Biomedical Engineering and Materials)
Intracellular Optogenetics Tools to Probe Biological Signaling Pathways
edited by
submission deadline 30 Sep 2025 | Viewed by 102 | Submission Open
Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Obesity-Related Metabolic Diseases: 2nd Edition
edited by Sandip Mukherjee
submission deadline 30 Sep 2025 | Viewed by 96 | Submission Open
Keywords: obesity; metabolism; adipose tissue; liver inflammation; hyperglycemia; hyperlipidemia; cardiovascular diseases; new drug targets; translational studies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
New Advances in the Pathology, Diagnosis and Treatment of Thyroid Tumors submission deadline 30 Sep 2025 | Viewed by 93 | Submission Open
Keywords: goitre; thyroid cancer; screening; bias; paraneoplastic syndrome  ; immunosurveillance  ; thyroiditis  ; thyroidectomy  ; immunotherapy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Interdisciplinary Perspectives on Protein Glycosylation, Signaling, and Toxicity in Biological Systems
edited by Ashutosh Pandey
submission deadline 30 Sep 2025 | Viewed by 92 | Submission Open
Keywords: glycosylation; signaling pathways; toxicity; environmental chemicals; animal models
(This special issue belongs to the Section Cell Biology and Pathology)
Diagnostic and Therapeutic Approaches to Pancreatic Cancer—Second Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 78 | Submission Open
Keywords: pancreatic cancer; systemic therapy; immunotherapy; tumor microenvironment; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Neuromuscular Diseases: Biochemical, Genetic, and Electrophysiological Studies
edited by
submission deadline 30 Sep 2025 | Viewed by 77 | Submission Open
Keywords: neuromuscular disorders; motor neuron diseases; myopathies; neuropathies; autoimmune neuromuscular diseases; electromyography; nerve conduction studies; epigenomics; genomics; new therapeutic approaches; myasthenia; mitochondrial disease
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Cytogenetics in Health and Diseases
edited by
submission deadline 30 Oct 2025 | Viewed by 63 | Submission Open
Keywords: genetic mutations; high-throughput sequencing; genomics; multiomics; rare diseases
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Pathological Biomarkers in Precision Medicine
edited by , Mirela A. Dobre and Tudor Groza
submission deadline 31 Oct 2025 | 7 articles | Viewed by 14204 | Submission Open
Keywords: pathological biomarkers; precision medicine; artificial intelligence; medical imaging; omics data analysis; personalized medicine; biomarker discovery; digital pathology
(This special issue belongs to the Section Cell Biology and Pathology)
Breast Cancer: New Diagnostic and Therapeutic Approaches
edited by , and Sara Bravaccini
submission deadline 31 Oct 2025 | 8 articles | Viewed by 13161 | Submission Open
Keywords: breast cancer; breast oncology; circulating tumor cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanisms and Pharmacological Targets for Pain
edited by Renan F. do Espírito-Santo
submission deadline 31 Oct 2025 | 4 articles | Viewed by 8118 | Submission Open
Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Issues in Retinal Degeneration submission deadline 31 Oct 2025 | 5 articles | Viewed by 7378 | Submission Open
Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Fetal Medicine and Neonatology submission deadline 31 Oct 2025 | 4 articles | Viewed by 6937 | Submission Open
Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Gastrointestinal Diseases
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 6171 | Submission Open
Keywords: precision medicine; artificial intelligence; eosinophilic gastrointestinal diseases; inflammatory bowel disease; irritable bowel syndrome; gastroesophageal reflux disease; gastrointestinal cancers; drug-resistant infections
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetic Research on Neuropsychiatric Disorders and Complex Human Diseases
edited by Wen Zhang
submission deadline 31 Oct 2025 | 5 articles | Viewed by 5747 | Submission Open
Keywords: neuropsychiatric disorders; complex human diseases; genetic research; omics data analysis; high-throughput sequencing; machine learning; disease mechanism
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanisms of Steroid Hormone Action—2nd Edition
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 5371 | Submission Open
Keywords: oestrogen; androgens; thyroid; adrenal gland; menopause; cancer
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases
edited by Jixin Zhong
submission deadline 31 Oct 2025 | 8 articles | Viewed by 5229 | Submission Open
Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Hypertrophic Cardiomyopathy
edited by Said Alsidawi, and
submission deadline 31 Oct 2025 | 6 articles | Viewed by 5041 | Submission Open
Keywords: hypertrophic cardiomyopathy; myosin inhibitors; genetic therapy; risk stratification
(This special issue belongs to the Section Molecular and Translational Medicine)
Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies submission deadline 31 Oct 2025 | 5 articles | Viewed by 4552 | Submission Open
Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Research in Atrial Fibrillation
edited by
submission deadline 31 Oct 2025 | 4 articles | Viewed by 4442 | Submission Open
Keywords: atrial fibrillation; arrhythmia; electrophysiology; cardiovascular; mechanism; laboratory; experimental
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research in Obesity, 2nd Edition
edited by Zaida Abad-Jiménez and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 4056 | Submission Open
Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathogenesis and Novel Therapeutics in Musculoskeletal Conditions, 3rd Edition submission deadline 31 Oct 2025 | 3 articles | Viewed by 3991 | Submission Open
Keywords: neck pain; low back pain; myofascial pain syndromes; chronic pain; musculoskeletal disorders; disability; pain treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Head and Neck Tumors, 4th Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 3749 | Submission Open
Keywords: head and neck tumors; predictive markers; liquid biopsy; therapy; precision medicine; biomaterials
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Novel Drug Discovery, Synthesis, and Evaluation
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3672 | Submission Open
Keywords: drug synthesis; novel therapies; disease targets; medicinal chemistry; computational methods; screening techniques; pharmaceutical development; target identification
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Gynecological Diseases in Cellular and Molecular Perspectives submission deadline 31 Oct 2025 | 3 articles | Viewed by 3245 | Submission Open
Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3164 | Submission Open
Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnosis, and Treatment of Respiratory Diseases
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3082 | Submission Open
Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia; tuberculosis; respiratory failure; ARDS; COVID-19; obstructive sleep apnea
(This special issue belongs to the Section Cell Biology and Pathology)
Maternal-Fetal and Neonatal Medicine submission deadline 31 Oct 2025 | 1 articles | Viewed by 3069 | Submission Open
Keywords: maternal– fetal health; neonatal health; prenatal care; prenatal diagnosis; fetal growth; diabetes mellitus; hypertension; pre-eclampsia; congenital infections; gene therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetic Regulation and Its Impact for Medicine (2nd Edition)
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3020 | Submission Open
Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Tumor Immunology submission deadline 31 Oct 2025 | 2 articles | Viewed by 2914 | Submission Open
Keywords: tumor immunity; immunotherapy; engineered immune cells; antibodies; immunomodulators; cytokines; survival; immune-checkpoint inhibitors; tumor immune microenvironment
(This special issue belongs to the Section Immunology and Immunotherapy)
Cell Signaling and Molecular Regulation in Neurodegenerative Disease
edited by Shao-Ming Wang
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2809 | Submission Open
Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders—2nd Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 2765 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2520 | Submission Open
Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels
(This special issue belongs to the Section Biomedical Engineering and Materials)
New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2373 | Submission Open
Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Innovative Approaches in In Vitro Skin Models: From Design to Application
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2360 | Submission Open
Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling
(This special issue belongs to the Section Biomedical Engineering and Materials)
Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition submission deadline 31 Oct 2025 | 2 articles | Viewed by 2336 | Submission Open
Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 2285 | Submission Open
Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition submission deadline 31 Oct 2025 | 3 articles | Viewed by 2187 | Submission Open
Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Developments in Mycobacterial Research submission deadline 31 Oct 2025 | 2 articles | Viewed by 2074 | Submission Open
Keywords: Mycobacterium tuberculosis; mycobacterial; host immune responses
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations
edited by , Rui Miguel Martins and
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2033 | Submission Open
Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
MicroRNA and Its Role in Human Health, 2nd Edition
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1963 | Submission Open
Keywords: microRNA; disease models; disease associations; molecular mechanism; molecular diagnosis; molecular therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition submission deadline 31 Oct 2025 | 2 articles | Viewed by 1748 | Submission Open
Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation
(This special issue belongs to the Section Molecular and Translational Medicine)
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