Nanoparticles in Medicine: The Potential of “Empty” Nanoparticles and Future Challenges
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Nanomedicine and Nanobiology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 18
Special Issue Editors
Interests: nanoparticle technology
Interests: surfactants, lipids, colloids and polymers; fluid dynamics of non-Newtonian flows; bulk and interfacial rheologies; thermodynamics phase behavior and Kinetics; self-assembly aggregates structure-property relation; surface tension measurement; microfluidics, microscale and 3D printing experiments
Special Issue Information
Dear Colleagues,
Particles with diameters of 100 nanometers or less are generally classified as nanoparticles. Among them, lipid-based nanoparticles—primarily single-walled micelles and bilayer liposomes—have been widely used in drug delivery applications. A substantial body of research documents their effectiveness, highlighting their ability to encapsulate therapeutic agents within their core or associate them with the particle surface. However, the therapeutic use of empty nanoparticles—those devoid of active encapsulated agents—is emerging as a novel and versatile approach in medical intervention. In this Special Issue, the biophysical and rheological properties of nanoparticles that have been discovered to date will be revealed. The wide range of demonstrated or potentially beneficial effects of empty nanoparticles in the treatment of shock due to infection or severe blood loss, the prevention of ischemia reperfusion injury, anticoagulation, reanimation after clinical death, the gene expression of brain stem cells, the gene expression of macrophages, the absorption of toxic mediators, the treatment of lethal infection, and the treatment of pneumonia, among other areas, will be shown. Future research directions and challenges will also be discussed.
Prof. Dr. Cuthbert O Simpkins
Dr. Zahra Niroobakhsh
Guest Editors
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Keywords
- nanoparticles
- empty nanoparticles
- nanoparticle technology
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