Shock Syndromes: Pathophysiology, Diagnostics and Emerging Therapeutics Across the Clinical Spectrum

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 17

Special Issue Editors


E-Mail Website
Guest Editor
3rd Department of Cardiology, “Sotiria” Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Interests: heart failure; cardiogenic shock; critical care; arrhythmia

E-Mail Website
Guest Editor
3rd Cardiology Department, “Sotiria” Chest Disease Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Interests: atherosclerosis; endothelium; heart failure; cardiovascular imaging; epidemiology
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Special Issue Information

Dear Colleagues,

Shock, as a life-threatening condition characterized by inadequate tissue perfusion and cellular oxygenation, remains a major challenge in acute and critical care medicine. This Special Issue will provide a comprehensive overview of shock syndromes, spanning the entire clinical spectrum from septic and cardiogenic to hypovolemic and obstructive shock, as well as mixed or less commonly studied forms. We invite original research articles, reviews, and clinical studies that explore underlying pathophysiological mechanisms, novel diagnostic tools including imaging and biomarkers, and innovative therapeutic approaches such as targeted pharmacologic strategies, mechanical circulatory support, and immunomodulation. Special emphasis will be given to precision medicine, translational research, and artificial intelligence applications that may reshape shock management. Through this Special Issue, we will bridge the gap between basic science and clinical practice, enhancing our understanding of shock syndromes and paving the way for improved patient outcomes.

Dr. George E. Zakynthinos
Dr. Evangelos Oikonomou
Guest Editors

Manuscript Submission Information

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Keywords

  • shock
  • critical illness
  • cardiogenic shock
  • septic shock
  • hypovolemic shock
  • obstructive shock
  • inflammation
  • hemodynamics
  • artificial intelligence in medicine
  • precision medicine
  • vasopressors
  • mechanical circulatory support
  • diagnostics

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Published Papers

This special issue is now open for submission.
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