New Treatments for Colorectal Cancer
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 9
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue, “New Treatments for Colorectal Cancer”, aims to explore the molecular mechanisms by which natural bioactive compounds regulate inflammation, oxidative stress, angiogenesis, and metastasis in various cancer models. Therapeutic interventions for advanced and metastatic colorectal cancer (CRC) have evolved significantly in recent years. A growing number of novel drugs are being developed, many of which focus on inhibiting oxidative stress-induced inflammatory responses, counteracting aberrant cancer signaling, and targeting the pathways that regulate tumor growth and proliferation. These advancements have provided oncologists with an expanding arsenal of therapeutic options for managing late-stage CRC. Numerous studies have demonstrated the potent antitumor properties of natural product extracts across various cancer types. These compounds exert their effects through multiple mechanisms, including the inhibition of proliferation, immune modulation, autophagy, and apoptosis. Given the ongoing challenges in CRC treatment, there is an urgent need for the development of more effective and better-tolerated chemotherapy regimens. Such innovations could play a critical role in overcoming the current limitations and improving patient outcomes in colorectal cancer treatment.
Dr. Dhiraj Kumar Sah
Guest Editor
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Keywords
- biomarkers
- signaling pathway
- chemotherapy
- reactive oxygen species
- angiogenesis
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