Molecular Pathways and Their Clinical Implications in Ischemic Heart Disease and Heart Failure: From Pathophysiology to Therapeutic Strategies
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 4
Special Issue Editors
Interests: heart failure; ischemic heart disease; atrial fibrillation; cardiometabolic diseases; precision medicine
2. Department of Emergency Medicine, AHEPA University Hospital, 54636 Thessaloniki, Greece
Interests: myocardial infarction; heart failure; coronary artery disease; atrial fibrillation; precision medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ischemic heart disease (IHD) and heart failure (HF) remain leading causes of morbidity and mortality worldwide, despite significant advancements in diagnosis and treatment. Understanding the underlying molecular mechanisms of these conditions is crucial for the development of targeted and effective therapeutic strategies. This Special Issue of Biomedicines aims to explore the latest insights into the molecular characterization of IHD and HF, from pathophysiological mechanisms to novel therapeutic approaches.
We welcome contributions that elucidate the role of inflammation, oxidative stress, mitochondrial dysfunction, and genetic/epigenetic modifications in the progression of IHD and HF. Studies on biomarkers, molecular imaging techniques, and innovative pharmacological or gene-based therapies are particularly encouraged. Additionally, research on personalized and precision medicine approaches for optimizing patient outcomes will be highly relevant.
This Special Issue invites original research articles, reviews, and clinical studies that enhance our understanding of molecular pathways in IHD and HF and pave the way for future translational applications. By bridging the gap between basic science and clinical practice, we aim to foster the development of cutting-edge, patient-centered treatment strategies.
Dr. Panagiotis Stachteas
Dr. Efstratios Karagiannidis
Guest Editors
Manuscript Submission Information
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Keywords
- ischemic heart disease
- heart failure
- molecular mechanisms
- biomarkers
- targeted therapy
- precision medicine
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