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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Cell and Tissue Engineering

edited by

Yoshitaka Miyamoto

submission deadline 30 Mar 2026 | Viewed by 96 | Submission Open

Keywords: cell and tissue engineering; regenerative medicine; stem cells; organoid; biomaterials; extracellular matrix (ECM); micro electro mechanical systems (MEMSs); microphysiological systems (MPSs); medical device; decellularization (decellularized tissue)

(This special issue belongs to the Section Biomedical Engineering and Materials)

Crohn’s Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Dingpei Long

and Junsik Sung

submission deadline 31 Mar 2026 | 17 articles | Viewed by 35075 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Cholinergic System Neurodegeneration: Novel Pharmacotherapy

edited by

Javier del Pino

and Paula Moyano

submission deadline 31 Mar 2026 | 1 articles | Viewed by 20026 | Submission Open

Keywords: cholinergic system; neurodegeneration; acetylcholine; cholinergic neurons; cholinergic pathologies; therapeutic approaches

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Long COVID: Mechanisms, Biomarkers, and Treatment

edited by

Frédérique Ponchel

submission deadline 31 Mar 2026 | 4 articles | Viewed by 17071 | Submission Open

Keywords: long-COVID; clinical observations; disease mechanism; biomarkers; treatment strategies; opinions

(This special issue belongs to the Section Cell Biology and Pathology)

Clinical Electrophysiology for Precision Diagnosis for Cardiology and Central Nervous System Diseases

edited by

Fátima Regina Mena Barreto Silva

and

Diana Marcela Aragon Novoa

submission deadline 31 Mar 2026 | 3 articles | Viewed by 16364 | Submission Open

Keywords: brain; cardiology; precision medicine.

(This special issue belongs to the Section Molecular and Translational Medicine)

Saving Lives from Myocardial Infarction: Prevention vs. Therapy

edited by Dong Wang

submission deadline 31 Mar 2026 | 4 articles | Viewed by 13724 | Submission Open

Keywords: myocardial infarction; molecular markers; AI-powered early detection; wearable devices; ischemia– reperfusion injury; artificial intelligence; ventricular remodeling; fibrosis control; molecular imaging; genomics; transcriptomics; proteomics; metabolomics; MI prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Lung Cancer: From Bench to Bedside

edited by

Seung Hyeun Lee

submission deadline 31 Mar 2026 | 8 articles | Viewed by 12282 | Submission Open

Keywords: lung cancer; immunotherapy; targeted therapy; translational oncology; biomarkers; EGFR; ALK; ROS1

(This special issue belongs to the Section Cancer Biology and Oncology)

Renal Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Silvio Maringhini

and

Riuko Ohashi

submission deadline 31 Mar 2026 | 4 articles | Viewed by 11526 | Submission Open

Keywords: renal cell carcinoma; pathology; physiology; diagnosis; multimodal treatment; drug resistance; biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated

edited by

Consolato M. Sergi

and

Paola Di Carlo

submission deadline 31 Mar 2026 | 4 articles | Viewed by 11202 | Submission Open

Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Multidisciplinary Management of Rare Head and Neck Tumors: The Importance of Knowing and Dealing with Them

edited by

Francesco Perri

submission deadline 31 Mar 2026 | 3 articles | Viewed by 10510 | Submission Open

Keywords: rare head and neck cancers; translational research; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Medicinal Cannabis: Advances in Therapeutics and Clinical Applications

edited by

Erin Berthold

submission deadline 31 Mar 2026 | 2 articles | Viewed by 9854 | Submission Open

Keywords: medicinal cannabis; cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN)

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Insights in Gastric, Colorectal, and Pancreatic Cancer

edited by

John K. Triantafillidis

submission deadline 31 Mar 2026 | 4 articles | Viewed by 8504 | Submission Open

Keywords: gastric cancer ; colorectal cancer ; pancreatic cancer; immunotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Connective Tissue Disorders: Pathogenetic, Diagnostic and Therapeutic Perspectives

edited by

Katarzyna Winsz-Szczotka

submission deadline 31 Mar 2026 | 3 articles | Viewed by 7656 | Submission Open

Keywords: connective tissue disorders; pathophysiological mechanisms; inflammation; autoimmunity; extracellular matrix; fibrosis; biomarkers; treatment; therapeutic targets

(This special issue belongs to the Section Molecular and Translational Medicine)

Gynecological Diseases in Cellular and Molecular Perspectives

edited by

Iwona Wertel

and

Anna Pawłowska-Łachut

submission deadline 31 Mar 2026 | 5 articles | Viewed by 6893 | Submission Open

Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions

(This special issue belongs to the Section Molecular and Translational Medicine)

Skin Diseases and Cell Therapy

edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum

submission deadline 31 Mar 2026 | 2 articles | Viewed by 6008 | Submission Open

Keywords: dermatology; psoriasis; atopic dermatitis; vitiligo; alopecia; cutaneous leishmaniasis; and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms

(This special issue belongs to the Section Gene and Cell Therapy)

Drug Resistance and Tumor Microenvironment in Human Cancers

edited by

Tiago Miguel Amaral Carvalho

Silvia Socorro

and Marília Isabel Neto Figueira

submission deadline 31 Mar 2026 | 2 articles | Viewed by 5851 | Submission Open

Keywords: cancer therapy; drug resistance; tumor microenvironment; targeted therapy; precision medicine; cancer-related mechanisms

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research in Thyroid and Parathyroid Diseases

edited by Anping Su

submission deadline 31 Mar 2026 | 5 articles | Viewed by 5031 | Submission Open

Keywords: thyroid cancer treatment; tumor microenvironment; immunotherapy; targeted therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics

edited by

Md Amdadul Huq

submission deadline 31 Mar 2026 | 1 articles | Viewed by 4676 | Submission Open

Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

New Advances in Ovarian Cancer

edited by

Zhenshan Yang

and

Hengrui Liu

submission deadline 31 Mar 2026 | 5 articles | Viewed by 4573 | Submission Open

Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation

edited by Chenzhou Hao, Jing Guo, Yin Sun and Tongchao Liu

submission deadline 31 Mar 2026 | 5 articles | Viewed by 4280 | Submission Open

Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure– activity relationship; structure– property relationship

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Stem Cell Therapy: Traps and Tricks

edited by

Martina Perše

and Željka Večerić-Haler

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4237 | Submission Open

Keywords: mesenchymal stem cells; MSC therapy; preclinical research; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Imaging Technology for Human Diseases

edited by Emanuele David

submission deadline 31 Mar 2026 | 4 articles | Viewed by 3785 | Submission Open

Keywords: technological advances; imaging; X-ray; mammography; CT; MRI; ultrasound; angiography

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Insights in Hypoxic Response Modulation

edited by Rafał Bartoszewski

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3755 | Submission Open

Keywords: hypoxia; oxygen homeostasis; oxidative damage; cell death; ischemic events; stroke; myocardial infarction; tumor microenvironment (TME); noncoding RNA; MicroRNAs; long noncoding RNAs; PiRNA; hypoxia-inducible factors (HIFs); targeted delivery; hypoxic cells; regulatory networks; therapeutic opportunities

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Insights in Thoracic Diseases: From Diagnostics to Biomarkers and Therapeutic Implications Through Interdisciplinarity

edited by

Radu Adrian Crisan-Dabija

and

Alexandru Burlacu

submission deadline 31 Mar 2026 | 4 articles | Viewed by 3665 | Submission Open

Keywords: chronic obstructive pulmonary disease; acute respiratory diseases; cardionephrology; interstitial lung disease; interventional cardiology; pulmonary fibrosis; tuberculosis; research methodology; biomarkers; therapeutics; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics

edited by

Abdelaziz Ghanemi

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3584 | Submission Open

Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis and Treatment of Ophthalmic Diseases

edited by

Da-Wen Lu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3520 | Submission Open

Keywords: ophthalmology; AI; ocular; eye diseases; retina; cornea; glaucoma; neuro-ophthalmology

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Immunotherapy and Radiation Therapy for Cancer (2nd Edition)

edited by

Ivaylo B. Mihaylov

and Benjamin Spieler

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3296 | Submission Open

Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response

(This special issue belongs to the Section Cancer Biology and Oncology)

Oral Cancer: From Pathophysiology to Novel Therapeutic Approach

edited by

Chan-Yen Kuo

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2975 | Submission Open

Keywords: oral cancer and pathophysiology; molecular mechanisms; biomarkers; immunological and targeted therapy; precision medicine and personalized therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Immune Cell Biology: Insights from Molecular Perspectives

edited by

Paolo Fagone

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2772 | Submission Open

Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders

(This special issue belongs to the Section Cell Biology and Pathology)

Diabetes Mellitus: Pharmacological Innovations and Related Therapeutic Benefits

edited by

Cristina-Mihaela Lăcătuşu

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2700 | Submission Open

Keywords: therapy of diabetes mellitus; pharmacological innovations; incretins; GLP-1 receptor agonists; SGLT-2 inhibitors; weight control; diabetes-related cardiovascular risk; non-glycemic benefits of diabetes drugs; diabetes-related technologies; diabetes outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Central Role of Mitochondrial Oxidative Stress in the Pathophysiology of Disorders (2nd Edition)

edited by

Guilhian Leipnitz

and André Quincozes-Santos

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2424 | Submission Open

Keywords: mitochondrial dysfunction; reactive oxygen species; bioenergetics; mitochondrial quality control; pathologies; protective agents

(This special issue belongs to the Section Molecular and Translational Medicine)

Skin Fibrosis and Cutaneous Wound Healing—2nd Edition

edited by

Noriko Aramaki-Hattori

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2366 | Submission Open

Keywords: fibroblasts; inflammation; fibrosis; cutaneous wound healing

(This special issue belongs to the Section Molecular and Translational Medicine)

Drug-Resistant Bacterial Infections and Alternative Therapies—2nd Edition

edited by

Vijay Singh Gondil

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2191 | Submission Open

Keywords: alternative agents; antibiotics; phages; endolysins; phytochemicals; drug discovery; nanoparticles; biofilms

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Biomarkers and Therapeutic Targets in Gastric Cancer: From Basic Research to Clinical Applications

edited by

Laura Georgiana Necula

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2179 | Submission Open

Keywords: gastric cancer; tumor microenvironment; gastric cancer metastasis; cancer stem cells; diagnosis and treatment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Medical Imaging in Brain Tumor: Charting the Future

edited by

Subrata Bhattacharjee

and

Mansoor Hayat

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2175 | Submission Open

Keywords: brain tumor diagnosis; artificial intelligence (AI) in medical imaging; imaging biomarkers for brain tumor; detection; segmentation and classification; radiomics and radiogenomics; precision oncology; deep learning and machine learning; neuro oncology; digital pathology; treatment response monitoring

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Microbial Metabolites and Their Impact on Gut Homeostasis

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2119 | Submission Open

Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Brain Imaging and Cognitive Deficits in Psychiatric Disorders, 2nd Edition

edited by

Wenbin Guo

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1973 | Submission Open

Keywords: cognitive deficits; psychiatric disorders; schizophrenia; brain imaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Trends in Regional Anesthesia and Pain Management

edited by

Jui-An Lin

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1898 | Submission Open

Keywords: regional anesthesia; ultrasound-guided/stimulator-guided nerve blocks; novel techniques for motor-sparing neural intervention; continuous catheter infusions; opioid-sparing techniques; perioperative pain management; novel local anesthetics; cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques; modalities (techniques; technologies; or drug regimen) to prolong the effect of local anesthetics; ERAS-related studies; AI applications in regional anesthesia and pain management; innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield; studies comparing new technologies/simulation (such as EpiFaith; SPRint PNS system; or CompuFlo) with traditional methods in improving regional anesthesia and pain management; regenerative medicine; nutritional pain medicine; application of bone marrow aspirate concentration or other stem cell components in pain medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovations and Perspectives in Kidney Transplantation

edited by Vassilis Filiopoulos

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1543 | Submission Open

Keywords: bioartificial kidney; immunology; immunosuppression; kidney transplantation; tolerance; graft rejection; graft survival; xenotransplantation; kidney regeneration

(This special issue belongs to the Section Immunology and Immunotherapy)

Recent Advances in Molecular Neuroimaging

edited by

Wenliang Fan

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1434 | Submission Open

Keywords: molecular neuroimaging; imaging techniques; clinical applications; imaging probes; personalized medicine; diagnostic imaging; therapeutic monitoring; clinical decision support

(This special issue belongs to the Section Molecular and Translational Medicine)

Drug Discovery, Development and Delivery: Current Status and Future Perspectives

edited by

Shafi Ullah Khan

and

Thet Thet Htar

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1369 | Submission Open

Keywords: drug discovery; rational drug design; computer-aided drug design (CADD); drug repurposing; artificial intelligence (AI) and machine learning (ML); cancer therapeutics; infectious diseases; natural products

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Skin Diseases

edited by Nazia M. Saiyed and

Noriko Aramaki-Hattori

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1133 | Submission Open

Keywords: skin diseases; dermatology; diagnostic innovations; targeted therapies; molecular mechanisms; immunodermatology; translational research; inflammatory skin disorders; clinical dermatology; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Endocrine Disease and Atherosclerosis

edited by

Sergio Martínez-Hervás

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1042 | Submission Open

Keywords: diabetes; dyslipidemia; obesity; insulin resistance; subclinical atherosclerosis; atherosclerosis; cardiovascular disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Noncoding RNAs (ncRNAs): The Role in Gene Regulation and Human Diseases

edited by

Liming Chen

and

Yuanshan Zhu

submission deadline 31 Mar 2026 | Viewed by 908 | Submission Open

Keywords: ncRNAs; genomic editing; epigenetics; stem cell biology and regenerative medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Current Perspectives on Human Papillomavirus (HPV)—Second Edition

edited by

Vanja Kaliterna

and

Tomislav Meštrović

submission deadline 31 Mar 2026 | 2 articles | Viewed by 876 | Submission Open

Keywords: human papillomavirus (HPV); molecular mechanisms; diagnosis; treatment; prevention; vaccination; screening; immunotherapy; cancer

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Genetic Insights and Pharmacogenomic Approaches in Cancer Treatment

edited by

Ana Fernández-Santander

submission deadline 31 Mar 2026 | 1 articles | Viewed by 840 | Submission Open

Keywords: pharmacogenetics; genetic basis; cancer treatments

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Psychiatry and Antipsychotics

edited by

László Péczely

submission deadline 31 Mar 2026 | 1 articles | Viewed by 786 | Submission Open

Keywords: psychiatric diseases; schizophrenia; antipsychotics; molecular psychiatry; molecular pathways; neurotransmitter systems; positive; negative and cognitive symptoms

(This special issue belongs to the Section Molecular and Translational Medicine)

High-Risk Atrial Fibrillation in Patients with Cardiovascular Disease: Diagnosis, Comprehensive Risk Assessment, Comorbidities, and Anticoagulation Strategies

edited by

Silvia Reverté-Villarroya

and

José-Luis Clúa-Espuny

submission deadline 31 Mar 2026 | 1 articles | Viewed by 697 | Submission Open

Keywords: atrial fibrillation; cardiovascular comorbidity; device-detected atrial fibrillation; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Target Identification and Drug Discovery

edited by

Fabio Altieri

submission deadline 31 Mar 2026 | Viewed by 629 | Submission Open

Keywords: drug discovery; biological target; bioactive compounds; pharmacology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Obesity and Obesity-Related Pathology

edited by

Adriana Grigoraș

submission deadline 31 Mar 2026 | 1 articles | Viewed by 597 | Submission Open

Keywords: obesity; obesity-related cardiovascular diseases; obesity-related chronic kidney diseases; diabetes mellitus; depression; obesity-related cancer; adipose tissue; adipocytes; cancer-associated adipocytes; obesity therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Displaying special issue 301-350 on page 7 of 16.

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