Advances in Natural and Synthetic Anticancer Agents: Mechanistic Insights and Translational Pathways

Dear Colleagues, 

Natural products and their synthetic derivatives, along with synthetic anticancer compounds, remain pivotal in the discovery of cancer therapies, providing distinctive structural diversity and significant biological activity. The emergence of high-throughput screening platforms, computational modelling, and molecular profiling technologies has significantly enhanced the efficiency and our mechanistic understanding of the identification of novel anticancer drugs. This Special Issue focuses on the identification and advancement of compounds derived from plant and marine sources, as well as metal-based agents and their synthetic counterparts, with a specific emphasis on their modulation of the critical signalling pathways involved in tumor progression, apoptosis, angiogenesis, metastasis, and drug resistance. We welcome the submission of papers that showcase novel screening methodologies, pathway-oriented drug design, and translational research that amalgamates mechanistic understanding with therapeutic advancement. Research that combines natural product libraries, synthetic chemistry, and delivery technologies that improve selectivity and bioavailability will attract extra attention. This Special Issue seeks to propel the advancement of natural product-inspired medicines for clinical use in oncology by integrating pathway-driven mechanistic investigations with contemporary discovery tools.

Dr. Gul-E-Saba Chaudhry
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.