Muscle and Bone Diseases: New Insights into Pathophysiology and Treatment

Dear Colleagues,

Muscle and bone diseases represent a broad spectrum of heterogeneous conditions, ranging from degenerative and metabolic disorders to inflammatory and neoplastic diseases. Despite their diverse etiologies, these conditions often share complex pathophysiological mechanisms that lead to progressive tissue dysfunction, disability, and reduced quality of life. Moreover, in the context of the aging population, the prevalence of disorders such as osteoporosis, sarcopenia and osteosarcopenia is steadily increasing and is associated with a higher risk of fractures, disability, and hospitalization, posing a significant burden on healthcare systems.

A deeper understanding of the molecular and cellular mechanisms underlying muscle and bone diseases is thus essential to identify new therapeutic targets, improve clinical management, and support the development of innovative treatment strategies.

The Special Issue, entitled “Muscle and Bone Diseases: New Insights into Pathophysiology and Treatment”, aims to collect original research articles and reviews addressing recent advances in the understanding of pathogenic mechanisms in muscle and bone diseases. Emerging diagnostic and therapeutic approaches are also welcome. Translational and clinical studies are particularly encouraged, especially those integrating biomolecular data, pathological findings, and clinical observations, to bridge the gap between basic research and clinical application.

Dr. Lorenzo Sanesi
Guest Editor

Manuscript Submission Information

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