Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Plant Genomics and Genome Editing
edited by Xuean Cui
submission deadline 31 Jul 2026 | Viewed by 364 | Submission Open
Keywords: plant genomes; plant genomics; genome sequencing; plant genome engineering; CRISPR/Cas; gene knock-out; gene knock-in; base editor; prime editor; genome editing tools; multiplex genome editing; gene expression regulation; plant trait improvement
(This special issue belongs to the Section Genetics and Genomics)
Mode of Action of Allelopathic Compounds
edited by and Paweł Staszek
submission deadline 31 Jul 2026 | Viewed by 256 | Submission Open
Keywords: metabolomics; phytotoxic potential; mode of action; sustainable bioherbicides; root exudates; plant– plant interaction; plant– microbe interaction; metabolic malformations; biosynthesis of allelochemicals
(This special issue belongs to the Section Plant Science)
Exploring the Role of Serotonin in Psychiatric Disorders
edited by
submission deadline 31 Jul 2026 | Viewed by 232 | Submission Open
Keywords: diet; drug treatments; enzymes; epigenetic; post translational modification; serotonin metabolism; serotonin receptors; serotonin transporters
(This special issue belongs to the Section Neuroscience)
Environmental and Nutritional Stress: Metabolic Consequences and Regulatory Strategies in Animals
edited by
submission deadline 31 Jul 2026 | Viewed by 141 | Submission Open
Keywords: stress physiology; metabolic dysfunction; environmental stress; nutritional stress; gut microbiota; bioactive compounds
(This special issue belongs to the Section Physiology)
Epilepsy: The Mechanisms of Seizure, Termination, and Biomarker Development
edited by
submission deadline 31 Jul 2026 | Viewed by 122 | Submission Open
Keywords: epilepsy; epileptogenesis; seizure mechanisms; seizure dynamics; termination; biomarkers; neural excitability; neuroscience
(This special issue belongs to the Section Neuroscience)
Animal Cognition and Decision Strategies: From Behaviour to Computation
edited by and
submission deadline 31 Jul 2026 | Viewed by 79 | Submission Open
Keywords: animal models; bio-inspired computation; brain– behaviour mapping; cognitive mechanisms; cognitive neuroscience; cognitive strategies; comparative cognition; computational modelling; decision-making; learning and adaptation; naturalistic behaviour; neural computation; neuroethology
(This special issue belongs to the Section Neuroscience)
Regulation of Gene Expression in Immune Cell Development and Function
edited by Bon Quy Trinh
submission deadline 31 Jul 2026 | Viewed by 56 | Submission Open
Keywords: noncoding RNA; enhancer; silencer; transposable element; epigenetics; chromatin structure and architecture; innate immunology; adaptive immunology; development; functions
(This special issue belongs to the Section Immunology)
Applications of Gene Expression Profiling in Human Disease
edited by
submission deadline 31 Jul 2026 | Viewed by 27 | Submission Open
Keywords: gene expression profile; biomarkers; cancer; complex disease
(This special issue belongs to the Section Genetics and Genomics)
Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services—3rd Edition submission deadline 31 Jul 2026 | Viewed by 16 | Submission Open
Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation
(This special issue belongs to the Section Marine Biology)
Ferroptosis: Mechanisms and Human Disease
edited by Chan-Yen Kuo
submission deadline 15 Aug 2026 | 3 articles | Viewed by 8073 | Submission Open
Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment
(This special issue belongs to the Section Cell Biology)
Changing Coral Reef Biodiversity and Function in the Anthropocene
edited by
submission deadline 15 Aug 2026 | Viewed by 367 | Submission Open
Keywords: anthropogenic stressors; coral reefs; climate change; biodiversity loss; marine conservation; ecological adaptation; ecosystem function; resilience
(This special issue belongs to the Section Marine Biology)
Role of CARD9 in Health and Diseases
edited by Zuberwasim Sayyad and Nikhil Sharma
submission deadline 15 Aug 2026 | Viewed by 131 | Submission Open
Keywords: CARD9; innate immunity; pattern recognition receptors; autophagy; apoptosis; inflammasome; reactive oxygen species; post-translational modifications; gut microbiota; inflammation and cancer
Recent Advances in Angiogenesis and Vascular Development submission deadline 15 Aug 2026 | Viewed by 25 | Submission Open
Keywords: vasculogenesis; angiogenesis; vascular differentiation markers; endothelial-to-mesenchymal transition (EndMT); mechanotransduction; endothelial function; endothelial damage
(This special issue belongs to the Section Cell Biology)
The Role of Autophagy and Macrophages in Modulating Immune Responses in Atherosclerosis
edited by and Aatira Vijay
submission deadline 25 Aug 2026 | Viewed by 133 | Submission Open
Keywords: atherosclerosis; macrophages; autophagy; immune regulation; chronic inflammation; plaque stability; lipid metabolism; efferocytosis; immunometabolism
Population Genetics and Conservation of Amphibians and Reptiles
edited by
submission deadline 25 Aug 2026 | Viewed by 78 | Submission Open
Keywords: conservation genetics; local adaptation; genetic diversity; amphibian; reptile; environmental change
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Animal Models of Arthritis
edited by Nevena Arsenović-Ranin and Biljana Bufan
submission deadline 30 Aug 2026 | 4 articles | Viewed by 10479 | Submission Open
Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine
(This special issue belongs to the Section Medical Biology)
Young Researchers in Neuroscience
edited by Yansheng Du
submission deadline 31 Aug 2026 | 4 articles | Viewed by 31921 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Bone Cell Biology
edited by Yohei Abe and
submission deadline 31 Aug 2026 | 7 articles | Viewed by 16983 | Submission Open
Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling
(This special issue belongs to the Section Cell Biology)
Biology, Ecology and Management of Harmful Algae
edited by Paul V. Zimba and
submission deadline 31 Aug 2026 | 6 articles | Viewed by 8809 | Submission Open
Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources
Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease submission deadline 31 Aug 2026 | 2 articles | Viewed by 8443 | Submission Open
Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle
Lipid Metabolism in Plant Growth and Development
edited by Xiaohong Yu and Yingqi Cai
submission deadline 31 Aug 2026 | 2 articles | Viewed by 4189 | Submission Open
Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process
(This special issue belongs to the Section Plant Science)
Cellular and Molecular Biology of Liver Diseases
edited by Matthew McMillin
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1504 | Submission Open
Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease
(This special issue belongs to the Section Cell Biology)
Host–Microbiome–Environment Interactions in Domestic and Wild Animals
edited by and Cesar A. Meza-Herrera
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1244 | Submission Open
Keywords: animal microbiome; environmental microbiota; host– microbiota interactions; wildlife microbiology; livestock health and productivity; microbiome and conservation; One Health approach; gut microbiota dynamics; microbial ecology; microbiome and reproduction; habitat– host microbiome linkages; multi-omics integration
(This special issue belongs to the Section Microbiology)
Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury submission deadline 31 Aug 2026 | 1 articles | Viewed by 1242 | Submission Open
Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury
(This special issue belongs to the Section Neuroscience)
Microbiology and Metabolomics in Reproductive Biology submission deadline 31 Aug 2026 | Viewed by 353 | Submission Open
Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health
(This special issue belongs to the Section Developmental and Reproductive Biology)
Advances in Cardiac and Vascular Biology: From Mechanisms to Pathophysiology
edited by and
submission deadline 31 Aug 2026 | Viewed by 228 | Submission Open
Keywords: cardiovascular biology; molecular mechanisms; cellular signaling; epigenomic regulation; vascular remodeling; metabolic reprogramming; cardiac pathophysiology
(This special issue belongs to the Section Physiology)
Bone Mechanics: From Cells to Organs, to Function submission deadline 31 Aug 2026 | 1 articles | Viewed by 209 | Submission Open
Keywords: bone mechanics; bone remodeling; mechanotransduction; structural analysis; functional morphology; bioengineering
(This special issue belongs to the Section Physiology)
Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control (2nd Edition) submission deadline 31 Aug 2026 | Viewed by 198 | Submission Open
Keywords: leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; vaccine
Biophysics of Exposome: Molecular Mechanisms of Action
edited by and Madhavi K. Ganapathiraju
submission deadline 31 Aug 2026 | Viewed by 164 | Submission Open
Keywords: computational biology; systems biology; mass spectrometry; protein– ligand networks; protein– protein interaction networks; metabolomics; proteomics; surface plasmon resonance; protein structure prediction; molecular docking; target fishing; machine learning; artificial intelligence
Current Status and Future Perspectives on Lipid Biology and Beyond submission deadline 31 Aug 2026 | Viewed by 131 | Submission Open
Keywords: lipids; fatty acids (FAs); omega-3 (FA); omega-6 (FA); cancer; cell biology; oxylipins; oxidative stress; lipidomics; lipid nanoparticles; personalized lipid-based therapies
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Fruits and Seeds of Tropical Plants: Conservation of Species, Ecological Importance and Quality Valorization
edited by Edna Ursulino Alves and Silvanda De Melo Silva
submission deadline 31 Aug 2026 | Viewed by 121 | Submission Open
Keywords: climate change; nature conservation; biodiversity; plant propagation; postharvest quality; metabolic profile; orchard management and quality
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Energy Metabolism, Genetics and Development in Drosophila
edited by
submission deadline 31 Aug 2026 | Viewed by 89 | Submission Open
Keywords: Drosophila; energy metabolism; development; epigenetics; non-coding RNAs; metabolic disease; growth; signaling pathway
(This special issue belongs to the Section Bioinformatics)
Research Progress on Metabolic Pathways in Neurodegenerative Diseases
edited by Ali H. Rafati
submission deadline 31 Aug 2026 | Viewed by 74 | Submission Open
Keywords: neurodegeneration; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; autophagy; neuroinflammation; biomarkers; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Mitochondrial Genomics of Arthropods
edited by Renfu Shao
submission deadline 31 Aug 2026 | Viewed by 59 | Submission Open
Keywords: mitochondrial genome architecture; transcriptional dynamics; translational mechanisms; comparative genomics; molecular evolution; arthropod phylogenetics; systematics; evolutionary biology
(This special issue belongs to the Section Genetics and Genomics)
Novel Mechanisms and Biological Processes in Redox and Inflammatory Signaling
edited by Shengchen Wang and
submission deadline 31 Aug 2026 | Viewed by 40 | Submission Open
Keywords: redox; inflammatory; oxidative stress; antioxidant; anti-inflammatory; signaling pathways
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Biogenesis and Function of Centrioles, Centrosomes, and Primary Cilia in Health and Disease submission deadline 31 Aug 2026 | Viewed by 35 | Submission Open
Keywords: centriole; centrosome; cilia
(This special issue belongs to the Section Cell Biology)
Uncovering the Role of T Cells in Immune Homeostasis and Immune Tolerance
edited by
submission deadline 31 Aug 2026 | Viewed by 19 | Submission Open
Keywords: regulatory T cells; immune tolerance; FOXP3; cytokine; suppression
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2026 | 6 articles | Viewed by 16944 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction
(This special issue belongs to the Section Microbiology)
Viral Infections in Animals: Pathogenesis and Immunity
edited by
submission deadline 1 Sep 2026 | 1 articles | Viewed by 1519 | Submission Open
Keywords: virus– host interactions; antiviral immunity; mechanisms of viral pathogenesis
(This special issue belongs to the Section Immunology)
Latest Discoveries in Non-Model Organisms and Non-Translational Biology submission deadline 8 Sep 2026 | Viewed by 140 | Submission Open
Keywords: basic biological research; non-translational biology; non-clinical biology; fundamental science; non-model organisms; model organisms; scientific curiosity– driven research; biological diversity; experimental biology; theoretical biology
Feature Papers on Developmental and Reproductive Biology
edited by
submission deadline 15 Sep 2026 | 11 articles | Viewed by 24444 | Submission Open
Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Molecular and Cellular Mechanisms of Neuroinflammation and Chronic Pain
edited by Mario Garcia-Dominguez
submission deadline 15 Sep 2026 | Viewed by 26 | Submission Open
Keywords: neuroinflammation; chronic pain; neuroimmune interactions; glial activation; cytokine signaling; synaptic plasticity; oxidative stress; epigenetic regulation; microglia and astrocytes; therapeutic targets
(This special issue belongs to the Section Neuroscience)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2026 | 5 articles | Viewed by 7720 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Molecular Basis of Bone Homeostasis and Skeletal Diseases
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5310 | Submission Open
Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Signalling Pathways in Cancer and Disease submission deadline 30 Sep 2026 | 5 articles | Viewed by 4871 | Submission Open
Keywords: cancer; signalling; metastasis; tumorigenesis; cancer targeting
(This special issue belongs to the Section Cancer Biology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2806 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1268 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Cell Signal Transduction
edited by
submission deadline 30 Sep 2026 | Viewed by 454 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2026 | Viewed by 404 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
More than a Shield: The Secret Functions of Epithelial Cells in Homeostasis and Infections
edited by and Na Zhao
submission deadline 30 Sep 2026 | Viewed by 231 | Submission Open
Keywords: epithelial diversity; signaling; homeostasis; immunity; infection; microbiome; inflammation; cytokines; antimicrobial peptides
(This special issue belongs to the Section Medical Biology)
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