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  • Review
  • Open Access

Glucose Metabolism Modulation as a Strategy to Enhance Cancer Radiotherapy

  • Shuaining Gao,
  • Xiaochang Liu,
  • Shi Chen and
  • Pingkun Zhou
Metabolites2025, 15(12), 793;https://doi.org/10.3390/metabo15120793 
(registering DOI)

12 December 2025

A systematic literature review of the PubMed database, filtering for publication dates up to and including October 2025, was conducted to identify relevant studies on glucose metabolism and radiotherapy. Radioresistance poses a major therapeutic chal...

  • Review
  • Open Access

Diagnosis and Management of Pediatric Non-Alcoholic Fatty Liver Disease: An Overview

  • Dalia Dop,
  • Vlad Pădureanu,
  • Rodica Pădureanu,
  • Carmen Elena Niculescu,
  • Ștefan Adrian Niculescu and
  • Iulia Rahela Marcu

12 December 2025

Non-alcoholic fatty liver disease (NAFLD) is the most common pediatric chronic liver disease worldwide, with an increasing prevalence, mainly due to the increase in childhood obesity and sedentary lifestyle. The pathogenesis of NAFLD is multifactoria...

  • Article
  • Open Access

12 December 2025

Background/Objectives: Cytochrome P450 (CYP) enzymes are crucial for drug metabolism, yet inter-individual variability in their activity remains a significant clinical challenge. Current phenotyping methods are often impractical or even impossible, p...

  • Article
  • Open Access
19 Views
11 Pages

Association of Oxidative Stress Biomarkers with Metabolic Parameters in Dairy Goats During the Periparturient Period

  • Giovanna Meli,
  • Valentina Fumo,
  • Wenning Chen,
  • Giovanni Savoini and
  • Guido Invernizzi

11 December 2025

Objective: This study aimed at detecting changes in redox balance (reactive oxygen species (ROS), serum antioxidant capacity (SAC) and oxidative stress index (OSi)) during the peripartum period in dairy goats and evaluating the relationship between o...

  • Article
  • Open Access
93 Views
14 Pages

Dietary Inorganic Nitrate Accelerates Cardiac Parasympathetic Recovery After Exercise in Older Women With Hypertension: A Secondary Analysis of A Randomised Crossover Study

  • Jonas Benjamim,
  • Leonardo Santos Lopes da Silva,
  • Yaritza Brito Alves Sousa,
  • Leonardo da Silva Gonçalves,
  • Guilherme da Silva Rodrigues,
  • Macário Arosti Rebelo,
  • José E. Tanus-Santos,
  • Vitor Engrácia Valenti and
  • Carlos R. Bueno

10 December 2025

Background/Objectives: Dietary inorganic nitrate (NO3−), primarily sourced from vegetables such as beetroot, has been shown to enhance nitric oxide (NO) bioavailability, with emerging evidence suggesting its potential to modulate autonomic func...

  • Article
  • Open Access
128 Views
19 Pages

Pathological Characteristics of a Quail Model with Hyperuricemia Combined with Hyperlipidemia

  • Shujia Liu,
  • Xinyu Feng,
  • Xinlong Liu,
  • Yan Lin,
  • Bing Zhang,
  • Zhijian Lin and
  • Yu Wang

10 December 2025

Objective: To explore the association between uric acid and the prevalence of hyperlipidemia via the NHANES database, a combined hyperuricemia–hyperlipidemia (HUA-HLP) quail model was subsequently established to investigate the pathological cha...

  • Article
  • Open Access
103 Views
20 Pages

Osmolytes vs. Anabolic Reserves: Contrasting Gonadal Metabolomes in Two Sympatric Mediterranean Sea Urchins

  • Estela Carbonell-Garzón,
  • Ricardo Ibanco-Cañete,
  • Pablo Sanchez-Jerez and
  • Frutos C. Marhuenda Egea

10 December 2025

Background an Objectives: The Mediterranean sea urchins Paracentrotus lividus and Arbacia lixula co-occur on shallow rocky reefs but display contrasting ecological and physiological traits. We compared their gonadal metabolomes to identify species-sp...

  • Case Report
  • Open Access
157 Views
12 Pages

Multi-Omics Characterization of a Novel SSR4 Variant in Congenital Disorders of Glycosylation

  • Nurulamin Abu Bakar,
  • Nurul Izzati Hamzan,
  • Elyssa Milus Majawit,
  • Siti Nurwani Ahmad Ridzuan,
  • Noor Hafizah Hassan,
  • Anasufiza Habib and
  • Lock-Hock Ngu

8 December 2025

Background: Congenital disorders of glycosylation (CDG) are rare inborn errors of metabolism with multisystemic manifestations. SSR4-CDG is an ultra-rare X-linked subtype caused by pathogenic variants in SSR4, a component of the translocon-associated...

  • Article
  • Open Access
177 Views
19 Pages

Investigation of Volatile Compounds in Varied Types of Gardenia White Teas Utilizing HS–SPME–GC–MS and Multivariate Analysis

  • Shenghong Zheng,
  • Chunju Peng,
  • Qi Huang,
  • Ke Zhang,
  • Zhengwen Niu,
  • Guanghui Zeng,
  • Huajing Kang and
  • Hongling Chai

5 December 2025

Gardenia tea is esteemed for its delicate and fragrant aroma. Background: However, there is a scarcity of studies focused on the aromatic properties of gardenia-scented white tea, particularly regarding how these aroma profiles evolve over different...

  • Review
  • Open Access
941 Views
21 Pages

5 December 2025

Background/Objectives: Ultra-processed foods (UPFs) have become a dominant component of the modern diet, paralleling the rise in obesity and chronic disease prevalence worldwide. This narrative review aims to synthesize evidence on how dietary proces...

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Metabolites - ISSN 2218-1989